JP2002539089A - 成長ホルモン分泌促進薬 - Google Patents

成長ホルモン分泌促進薬

Info

Publication number
JP2002539089A
JP2002539089A JP2000599774A JP2000599774A JP2002539089A JP 2002539089 A JP2002539089 A JP 2002539089A JP 2000599774 A JP2000599774 A JP 2000599774A JP 2000599774 A JP2000599774 A JP 2000599774A JP 2002539089 A JP2002539089 A JP 2002539089A
Authority
JP
Japan
Prior art keywords
mmol
product
preparation
give
embedded image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000599774A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002539089A5 (es
Inventor
ジェフリー・アラン・ドッジ
チャールズ・ウィリス・ラガー・ザ・サード
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of JP2002539089A publication Critical patent/JP2002539089A/ja
Publication of JP2002539089A5 publication Critical patent/JP2002539089A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
JP2000599774A 1999-02-19 2000-02-18 成長ホルモン分泌促進薬 Pending JP2002539089A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12081399P 1999-02-19 1999-02-19
US60/120,813 1999-02-19
PCT/US2000/004274 WO2000049037A1 (en) 1999-02-19 2000-02-18 Growth hormone secretagogues

Publications (2)

Publication Number Publication Date
JP2002539089A true JP2002539089A (ja) 2002-11-19
JP2002539089A5 JP2002539089A5 (es) 2007-07-05

Family

ID=22392709

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000599774A Pending JP2002539089A (ja) 1999-02-19 2000-02-18 成長ホルモン分泌促進薬

Country Status (13)

Country Link
EP (1) EP1153034B1 (es)
JP (1) JP2002539089A (es)
CN (1) CN1179972C (es)
AR (1) AR023369A1 (es)
AT (1) ATE375996T1 (es)
AU (1) AU765642B2 (es)
BR (1) BR0008321A (es)
CA (1) CA2362303A1 (es)
CO (1) CO5160260A1 (es)
DE (1) DE60036785D1 (es)
IL (1) IL144350A0 (es)
PE (1) PE20001468A1 (es)
WO (1) WO2000049037A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6639076B1 (en) 1998-08-18 2003-10-28 Eli Lilly And Company Growth hormone secretagogues
US6828331B1 (en) 1999-02-19 2004-12-07 Eli Lilly And Company Growth hormone secretagogues
AU2001264977B2 (en) 2000-05-30 2005-04-14 Merck & Co., Inc. Melanocortin receptor agonists
US6756385B2 (en) * 2000-07-31 2004-06-29 Pfizer Inc. Imidazole derivatives
GT200100147A (es) * 2000-07-31 2002-06-25 Derivados de imidazol
WO2002032878A1 (en) * 2000-10-13 2002-04-25 Eli Lilly And Company Resolution process for preparation of substantially pure (r) and (s) enantiomers of 2-(4-nitroimidazolyl)-4-methoxyphenylpropionic acid and salts thereof
KR100593510B1 (ko) * 2001-01-23 2006-06-28 가도르 에스.에이. 골의 대사성 질병의 예방 및/또는 치료를 위한비스포스포네이트 함유 조성물, 그 조성물의 제조방법 및그의 이용
US7125840B2 (en) 2001-10-09 2006-10-24 Eli Lilly And Company Substituted dipeptides as growth hormone secretagogues
ES2271557T3 (es) 2002-04-09 2007-04-16 Eli Lilly And Company Secretagogos dipeptidicos de la hormona del crecimiento.
RS50595B (sr) * 2004-03-23 2010-05-07 Pfizer Products Incorporated Jedinjenja imidazola za lečenje neurodegenerativnih poremećaja
EP1940802A2 (en) 2005-09-22 2008-07-09 Pfizer Products Inc. Imidazole compounds for the treatment of neurological disorders
US10590087B1 (en) 2019-08-09 2020-03-17 Pfizer Inc. Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof
US11884634B2 (en) 2019-08-09 2024-01-30 Pfizer Inc. Compositions of solid forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4- tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide
US11504354B1 (en) 2021-09-08 2022-11-22 SpringWorks Therapeutics Inc.. Chlorinated tetralin compounds and pharmaceutical compositions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL107836A (en) * 1992-12-11 1998-01-04 Merck & Co Inc Spiro piperidines and homologues, their preparation and pharmaceutical preparations containing them
SK282166B6 (sk) * 1992-12-11 2001-11-06 Merck & Co., Inc. Spiropiperidínové deriváty, spôsob ich výroby a farmaceutický prostriedok s ich obsahom
US5721250A (en) * 1993-12-23 1998-02-24 Merck & Co. Inc. Di-and tri-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone
WO1998016527A1 (en) * 1996-10-15 1998-04-23 Fujisawa Pharmaceutical Co., Ltd. Benzoxepine derivatives which promote release of growth hormone
ZA987385B (en) * 1997-08-19 2000-04-18 Lilly Co Eli Growth hormone secretagogues.
ZA987383B (en) * 1997-08-19 2000-02-17 Lilly Co Eli Treatment of congestive heart failure with growth hormone secretagogues.

Also Published As

Publication number Publication date
CO5160260A1 (es) 2002-05-30
DE60036785D1 (de) 2007-11-29
CN1347420A (zh) 2002-05-01
AU765642B2 (en) 2003-09-25
IL144350A0 (en) 2002-05-23
AR023369A1 (es) 2002-09-04
EP1153034A1 (en) 2001-11-14
CN1179972C (zh) 2004-12-15
BR0008321A (pt) 2002-01-29
AU3496800A (en) 2000-09-04
ATE375996T1 (de) 2007-11-15
EP1153034B1 (en) 2007-10-17
CA2362303A1 (en) 2000-08-24
WO2000049037A1 (en) 2000-08-24
PE20001468A1 (es) 2000-12-20

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