DE60036785D1 - Sekretionsfordermittel fur wachtumshormon - Google Patents

Sekretionsfordermittel fur wachtumshormon

Info

Publication number
DE60036785D1
DE60036785D1 DE60036785T DE60036785T DE60036785D1 DE 60036785 D1 DE60036785 D1 DE 60036785D1 DE 60036785 T DE60036785 T DE 60036785T DE 60036785 T DE60036785 T DE 60036785T DE 60036785 D1 DE60036785 D1 DE 60036785D1
Authority
DE
Germany
Prior art keywords
hormon
guardian
secretion
requirements
secretion requirements
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60036785T
Other languages
English (en)
Inventor
Jeffrey Alan Dodge
Charles Willis Lugar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE60036785D1 publication Critical patent/DE60036785D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE60036785T 1999-02-19 2000-02-18 Sekretionsfordermittel fur wachtumshormon Expired - Lifetime DE60036785D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12081399P 1999-02-19 1999-02-19
PCT/US2000/004274 WO2000049037A1 (en) 1999-02-19 2000-02-18 Growth hormone secretagogues

Publications (1)

Publication Number Publication Date
DE60036785D1 true DE60036785D1 (de) 2007-11-29

Family

ID=22392709

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60036785T Expired - Lifetime DE60036785D1 (de) 1999-02-19 2000-02-18 Sekretionsfordermittel fur wachtumshormon

Country Status (13)

Country Link
EP (1) EP1153034B1 (de)
JP (1) JP2002539089A (de)
CN (1) CN1179972C (de)
AR (1) AR023369A1 (de)
AT (1) ATE375996T1 (de)
AU (1) AU765642B2 (de)
BR (1) BR0008321A (de)
CA (1) CA2362303A1 (de)
CO (1) CO5160260A1 (de)
DE (1) DE60036785D1 (de)
IL (1) IL144350A0 (de)
PE (1) PE20001468A1 (de)
WO (1) WO2000049037A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6639076B1 (en) 1998-08-18 2003-10-28 Eli Lilly And Company Growth hormone secretagogues
US6828331B1 (en) 1999-02-19 2004-12-07 Eli Lilly And Company Growth hormone secretagogues
AU2001264977B2 (en) 2000-05-30 2005-04-14 Merck & Co., Inc. Melanocortin receptor agonists
US6756385B2 (en) * 2000-07-31 2004-06-29 Pfizer Inc. Imidazole derivatives
GT200100147A (es) * 2000-07-31 2002-06-25 Derivados de imidazol
WO2002032878A1 (en) * 2000-10-13 2002-04-25 Eli Lilly And Company Resolution process for preparation of substantially pure (r) and (s) enantiomers of 2-(4-nitroimidazolyl)-4-methoxyphenylpropionic acid and salts thereof
KR100593510B1 (ko) 2001-01-23 2006-06-28 가도르 에스.에이. 골의 대사성 질병의 예방 및/또는 치료를 위한비스포스포네이트 함유 조성물, 그 조성물의 제조방법 및그의 이용
US7125840B2 (en) 2001-10-09 2006-10-24 Eli Lilly And Company Substituted dipeptides as growth hormone secretagogues
ATE338767T1 (de) * 2002-04-09 2006-09-15 Lilly Co Eli Dipeptidische wachstumshormonsekretionsförderern
GEP20084420B (en) * 2004-03-23 2008-07-10 Pfizer Prod Inc Use of imidazole compounds for the treatment of neurodegenerative disorders
KR20080040010A (ko) 2005-09-22 2008-05-07 화이자 프로덕츠 인코포레이티드 신경계 질환 치료용 이미다졸 화합물
US11884634B2 (en) 2019-08-09 2024-01-30 Pfizer Inc. Compositions of solid forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4- tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide
US10590087B1 (en) 2019-08-09 2020-03-17 Pfizer Inc. Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof
AR126961A1 (es) 2021-09-01 2023-12-06 Springworks Therapeutics Inc Sintesis de nirogacestat
US11504354B1 (en) 2021-09-08 2022-11-22 SpringWorks Therapeutics Inc.. Chlorinated tetralin compounds and pharmaceutical compositions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL107836A (en) * 1992-12-11 1998-01-04 Merck & Co Inc Spiro piperidines and homologues, their preparation and pharmaceutical preparations containing them
CZ151495A3 (en) * 1992-12-11 1995-12-13 Merck & Co Inc Spiropiperidine derivatives, process of their preparation and a pharmaceutical composition containing thereof
US5721250A (en) * 1993-12-23 1998-02-24 Merck & Co. Inc. Di-and tri-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone
JP2001502319A (ja) * 1996-10-15 2001-02-20 藤沢薬品工業株式会社 成長ホルモンの放出を促進するベンズオキセピン誘導体
ZA987385B (en) * 1997-08-19 2000-04-18 Lilly Co Eli Growth hormone secretagogues.
ZA987383B (en) * 1997-08-19 2000-02-17 Lilly Co Eli Treatment of congestive heart failure with growth hormone secretagogues.

Also Published As

Publication number Publication date
PE20001468A1 (es) 2000-12-20
AU765642B2 (en) 2003-09-25
AU3496800A (en) 2000-09-04
EP1153034B1 (de) 2007-10-17
AR023369A1 (es) 2002-09-04
JP2002539089A (ja) 2002-11-19
IL144350A0 (en) 2002-05-23
CO5160260A1 (es) 2002-05-30
ATE375996T1 (de) 2007-11-15
CN1179972C (zh) 2004-12-15
EP1153034A1 (de) 2001-11-14
CA2362303A1 (en) 2000-08-24
BR0008321A (pt) 2002-01-29
WO2000049037A1 (en) 2000-08-24
CN1347420A (zh) 2002-05-01

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Legal Events

Date Code Title Description
8332 No legal effect for de