PE20001468A1 - Compuestos no peptidicos como secretagogos de la hormona del crecimiento - Google Patents
Compuestos no peptidicos como secretagogos de la hormona del crecimientoInfo
- Publication number
- PE20001468A1 PE20001468A1 PE2000000127A PE0001272000A PE20001468A1 PE 20001468 A1 PE20001468 A1 PE 20001468A1 PE 2000000127 A PE2000000127 A PE 2000000127A PE 0001272000 A PE0001272000 A PE 0001272000A PE 20001468 A1 PE20001468 A1 PE 20001468A1
- Authority
- PE
- Peru
- Prior art keywords
- growth hormone
- secretagogs
- peptidic compounds
- refers
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Physical Education & Sports Medicine (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
SE REFIERE A UN COMPUESTO NO PEPTIDICOS DE FORMULA I DONDE R1 ES C6H5CH2OCH2-, C6H5(CH2)3-, INDOL-3-ILMETILO; Y ES PIRROLIDINILO, 4-METILPIPERIDINILO, NR2R2; R2 ES ALQUILO C1-C6; R3 ES 2-NAFTILO, FENILO SUSTITUIDO CON W; W ES H, F, CF3, ALCOXI C1-C6, FENILO; R4 ES H, CH3. SE REFIERE TAMBIEN A UNA FORMULACION ADEMAS CONTIENE UN AGENTE DE ANTIREABSORCION OSEA TAL COMO BISFOSFONATO. LOS COMPUESTOS NO PEPTIDICOS TIENEN ACTIVIDAD COMO SECRETAGOGOS DE LA HORMONA DE CRECIMIENTO POR LO QUE PUEDEN SER UTIL PARA EL TRATAMIENTO DE LA DEFICIENCIAS EN HORMONA DEL CRECIMIENTO EN VACAS, OVEJAS, AVES DE CORRAL
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12081399P | 1999-02-19 | 1999-02-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20001468A1 true PE20001468A1 (es) | 2000-12-20 |
Family
ID=22392709
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2000000127A PE20001468A1 (es) | 1999-02-19 | 2000-02-18 | Compuestos no peptidicos como secretagogos de la hormona del crecimiento |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1153034B1 (es) |
JP (1) | JP2002539089A (es) |
CN (1) | CN1179972C (es) |
AR (1) | AR023369A1 (es) |
AT (1) | ATE375996T1 (es) |
AU (1) | AU765642B2 (es) |
BR (1) | BR0008321A (es) |
CA (1) | CA2362303A1 (es) |
CO (1) | CO5160260A1 (es) |
DE (1) | DE60036785D1 (es) |
IL (1) | IL144350A0 (es) |
PE (1) | PE20001468A1 (es) |
WO (1) | WO2000049037A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6639076B1 (en) | 1998-08-18 | 2003-10-28 | Eli Lilly And Company | Growth hormone secretagogues |
US6828331B1 (en) | 1999-02-19 | 2004-12-07 | Eli Lilly And Company | Growth hormone secretagogues |
AU2001264977B2 (en) | 2000-05-30 | 2005-04-14 | Merck & Co., Inc. | Melanocortin receptor agonists |
US6756385B2 (en) * | 2000-07-31 | 2004-06-29 | Pfizer Inc. | Imidazole derivatives |
GT200100147A (es) * | 2000-07-31 | 2002-06-25 | Derivados de imidazol | |
WO2002032878A1 (en) * | 2000-10-13 | 2002-04-25 | Eli Lilly And Company | Resolution process for preparation of substantially pure (r) and (s) enantiomers of 2-(4-nitroimidazolyl)-4-methoxyphenylpropionic acid and salts thereof |
KR100593510B1 (ko) * | 2001-01-23 | 2006-06-28 | 가도르 에스.에이. | 골의 대사성 질병의 예방 및/또는 치료를 위한비스포스포네이트 함유 조성물, 그 조성물의 제조방법 및그의 이용 |
US7125840B2 (en) | 2001-10-09 | 2006-10-24 | Eli Lilly And Company | Substituted dipeptides as growth hormone secretagogues |
ES2271557T3 (es) | 2002-04-09 | 2007-04-16 | Eli Lilly And Company | Secretagogos dipeptidicos de la hormona del crecimiento. |
RS50595B (sr) * | 2004-03-23 | 2010-05-07 | Pfizer Products Incorporated | Jedinjenja imidazola za lečenje neurodegenerativnih poremećaja |
EP1940802A2 (en) | 2005-09-22 | 2008-07-09 | Pfizer Products Inc. | Imidazole compounds for the treatment of neurological disorders |
US10590087B1 (en) | 2019-08-09 | 2020-03-17 | Pfizer Inc. | Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof |
US11884634B2 (en) | 2019-08-09 | 2024-01-30 | Pfizer Inc. | Compositions of solid forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4- tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide |
US11504354B1 (en) | 2021-09-08 | 2022-11-22 | SpringWorks Therapeutics Inc.. | Chlorinated tetralin compounds and pharmaceutical compositions |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL107836A (en) * | 1992-12-11 | 1998-01-04 | Merck & Co Inc | Spiro piperidines and homologues, their preparation and pharmaceutical preparations containing them |
SK282166B6 (sk) * | 1992-12-11 | 2001-11-06 | Merck & Co., Inc. | Spiropiperidínové deriváty, spôsob ich výroby a farmaceutický prostriedok s ich obsahom |
US5721250A (en) * | 1993-12-23 | 1998-02-24 | Merck & Co. Inc. | Di-and tri-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone |
WO1998016527A1 (en) * | 1996-10-15 | 1998-04-23 | Fujisawa Pharmaceutical Co., Ltd. | Benzoxepine derivatives which promote release of growth hormone |
ZA987385B (en) * | 1997-08-19 | 2000-04-18 | Lilly Co Eli | Growth hormone secretagogues. |
ZA987383B (en) * | 1997-08-19 | 2000-02-17 | Lilly Co Eli | Treatment of congestive heart failure with growth hormone secretagogues. |
-
2000
- 2000-02-17 CO CO00011043A patent/CO5160260A1/es unknown
- 2000-02-18 PE PE2000000127A patent/PE20001468A1/es not_active Application Discontinuation
- 2000-02-18 IL IL14435000A patent/IL144350A0/xx unknown
- 2000-02-18 CN CNB008037035A patent/CN1179972C/zh not_active Expired - Fee Related
- 2000-02-18 DE DE60036785T patent/DE60036785D1/de not_active Expired - Lifetime
- 2000-02-18 WO PCT/US2000/004274 patent/WO2000049037A1/en active IP Right Grant
- 2000-02-18 BR BR0008321-6A patent/BR0008321A/pt not_active IP Right Cessation
- 2000-02-18 AT AT00913536T patent/ATE375996T1/de not_active IP Right Cessation
- 2000-02-18 JP JP2000599774A patent/JP2002539089A/ja active Pending
- 2000-02-18 AU AU34968/00A patent/AU765642B2/en not_active Ceased
- 2000-02-18 EP EP00913536A patent/EP1153034B1/en not_active Expired - Lifetime
- 2000-02-18 CA CA002362303A patent/CA2362303A1/en not_active Abandoned
- 2000-02-18 AR ARP000100708A patent/AR023369A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
CO5160260A1 (es) | 2002-05-30 |
DE60036785D1 (de) | 2007-11-29 |
CN1347420A (zh) | 2002-05-01 |
AU765642B2 (en) | 2003-09-25 |
IL144350A0 (en) | 2002-05-23 |
AR023369A1 (es) | 2002-09-04 |
EP1153034A1 (en) | 2001-11-14 |
CN1179972C (zh) | 2004-12-15 |
BR0008321A (pt) | 2002-01-29 |
AU3496800A (en) | 2000-09-04 |
ATE375996T1 (de) | 2007-11-15 |
EP1153034B1 (en) | 2007-10-17 |
JP2002539089A (ja) | 2002-11-19 |
CA2362303A1 (en) | 2000-08-24 |
WO2000049037A1 (en) | 2000-08-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application declared void or lapsed |