ATE375996T1 - Sekretionsfordermittel fur wachtumshormon - Google Patents

Sekretionsfordermittel fur wachtumshormon

Info

Publication number
ATE375996T1
ATE375996T1 AT00913536T AT00913536T ATE375996T1 AT E375996 T1 ATE375996 T1 AT E375996T1 AT 00913536 T AT00913536 T AT 00913536T AT 00913536 T AT00913536 T AT 00913536T AT E375996 T1 ATE375996 T1 AT E375996T1
Authority
AT
Austria
Prior art keywords
growth hormone
secretion promoters
promoters
secretion
hormone
Prior art date
Application number
AT00913536T
Other languages
English (en)
Inventor
Jeffrey Dodge
Charles Lugar
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE375996T1 publication Critical patent/ATE375996T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT00913536T 1999-02-19 2000-02-18 Sekretionsfordermittel fur wachtumshormon ATE375996T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12081399P 1999-02-19 1999-02-19

Publications (1)

Publication Number Publication Date
ATE375996T1 true ATE375996T1 (de) 2007-11-15

Family

ID=22392709

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00913536T ATE375996T1 (de) 1999-02-19 2000-02-18 Sekretionsfordermittel fur wachtumshormon

Country Status (13)

Country Link
EP (1) EP1153034B1 (de)
JP (1) JP2002539089A (de)
CN (1) CN1179972C (de)
AR (1) AR023369A1 (de)
AT (1) ATE375996T1 (de)
AU (1) AU765642B2 (de)
BR (1) BR0008321A (de)
CA (1) CA2362303A1 (de)
CO (1) CO5160260A1 (de)
DE (1) DE60036785D1 (de)
IL (1) IL144350A0 (de)
PE (1) PE20001468A1 (de)
WO (1) WO2000049037A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6639076B1 (en) 1998-08-18 2003-10-28 Eli Lilly And Company Growth hormone secretagogues
US6828331B1 (en) 1999-02-19 2004-12-07 Eli Lilly And Company Growth hormone secretagogues
JP2003534377A (ja) 2000-05-30 2003-11-18 メルク エンド カムパニー インコーポレーテッド メラノコルチン受容体作働薬
US6756385B2 (en) * 2000-07-31 2004-06-29 Pfizer Inc. Imidazole derivatives
GT200100147A (es) * 2000-07-31 2002-06-25 Derivados de imidazol
US20040106665A1 (en) * 2000-10-13 2004-06-03 Kress Thomas Joseph Resolution process for preparation of substantially pure (r) and (s) enantiomers of 2-(4-nitroimidazolyl)-4-methodxyphenylpropionic acid and salts thereof
US7560490B2 (en) 2001-01-23 2009-07-14 Gador S.A. Composition comprising bisphosphonates for prevention and/or treatment of metabolic diseases of bones, process for preparing such composition and use thereof
US7125840B2 (en) 2001-10-09 2006-10-24 Eli Lilly And Company Substituted dipeptides as growth hormone secretagogues
DE60306636T2 (de) * 2002-04-09 2007-07-05 Eli Lilly And Co., Indianapolis Wachstumhormonsekretionsförderer
RS50595B (sr) * 2004-03-23 2010-05-07 Pfizer Products Incorporated Jedinjenja imidazola za lečenje neurodegenerativnih poremećaja
EP1940802A2 (de) 2005-09-22 2008-07-09 Pfizer Products Inc. Imidazolverbindungen zur behandlung neurologischer erkrankungen
US11884634B2 (en) 2019-08-09 2024-01-30 Pfizer Inc. Compositions of solid forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4- tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide
KR20250030524A (ko) 2019-08-09 2025-03-05 화이자 인코포레이티드 (s)-2-(((s)-6,8-디플루오로-1,2,3,4-테트라하이드로나프탈렌-2-일)아미노)-n-(1-(2-메틸-1-(네오펜틸아미노)프로판-2-일)-1h-이미다졸-4-일)펜탄아미드의고체 상태 형태 및 이의 용도
JP2024530795A (ja) 2021-09-01 2024-08-23 スプリングワークス、セラピューティクス、インコーポレイテッド ニロガセスタットの合成
US11504354B1 (en) 2021-09-08 2022-11-22 SpringWorks Therapeutics Inc.. Chlorinated tetralin compounds and pharmaceutical compositions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT72076A (en) * 1992-12-11 1996-03-28 Merck & Co Inc Process for preparing spiro piperidines and homologs which promote release of growth hormone and pharmaceutical compositions containing them
IL107836A (en) * 1992-12-11 1998-01-04 Merck & Co Inc Spiro piperidines and homologues, their preparation and pharmaceutical preparations containing them
US5721250A (en) * 1993-12-23 1998-02-24 Merck & Co. Inc. Di-and tri-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone
JP2001502319A (ja) * 1996-10-15 2001-02-20 藤沢薬品工業株式会社 成長ホルモンの放出を促進するベンズオキセピン誘導体
ZA987385B (en) * 1997-08-19 2000-04-18 Lilly Co Eli Growth hormone secretagogues.
ZA987383B (en) * 1997-08-19 2000-02-17 Lilly Co Eli Treatment of congestive heart failure with growth hormone secretagogues.

Also Published As

Publication number Publication date
AU3496800A (en) 2000-09-04
AU765642B2 (en) 2003-09-25
PE20001468A1 (es) 2000-12-20
AR023369A1 (es) 2002-09-04
DE60036785D1 (de) 2007-11-29
EP1153034A1 (de) 2001-11-14
CA2362303A1 (en) 2000-08-24
EP1153034B1 (de) 2007-10-17
IL144350A0 (en) 2002-05-23
CN1179972C (zh) 2004-12-15
JP2002539089A (ja) 2002-11-19
CN1347420A (zh) 2002-05-01
CO5160260A1 (es) 2002-05-30
WO2000049037A1 (en) 2000-08-24
BR0008321A (pt) 2002-01-29

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties