JP2002535407A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2002535407A5 JP2002535407A5 JP2000596008A JP2000596008A JP2002535407A5 JP 2002535407 A5 JP2002535407 A5 JP 2002535407A5 JP 2000596008 A JP2000596008 A JP 2000596008A JP 2000596008 A JP2000596008 A JP 2000596008A JP 2002535407 A5 JP2002535407 A5 JP 2002535407A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pharmaceutically acceptable
- formula
- acceptable salt
- triazolo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9901744.4 | 1999-01-27 | ||
| GBGB9901743.6A GB9901743D0 (en) | 1999-01-27 | 1999-01-27 | Therapeutic agents |
| GB9901743.6 | 1999-01-27 | ||
| GBGB9901744.4A GB9901744D0 (en) | 1999-01-27 | 1999-01-27 | Therapeutic agents |
| GBGB9912429.9A GB9912429D0 (en) | 1999-05-27 | 1999-05-27 | Therapeutic agents |
| GB9912429.9 | 1999-05-27 | ||
| PCT/GB2000/000183 WO2000044752A1 (en) | 1999-01-27 | 2000-01-19 | Triazolo-pyridazine derivatives as ligands for gaba receptors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002535407A JP2002535407A (ja) | 2002-10-22 |
| JP2002535407A5 true JP2002535407A5 (enExample) | 2007-03-08 |
Family
ID=27269629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000596008A Withdrawn JP2002535407A (ja) | 1999-01-27 | 2000-01-19 | Ｇａｂａ受容体のリガンドとしてのトリアゾロピリダジン誘導体 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6500828B1 (enExample) |
| EP (1) | EP1149102B1 (enExample) |
| JP (1) | JP2002535407A (enExample) |
| AT (1) | ATE284403T1 (enExample) |
| AU (1) | AU772947B2 (enExample) |
| CA (1) | CA2359008C (enExample) |
| DE (1) | DE60016566T2 (enExample) |
| ES (1) | ES2232416T3 (enExample) |
| WO (1) | WO2000044752A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0000564D0 (en) | 2000-01-11 | 2000-03-01 | Merck Sharp & Dohme | Therapeutic agents |
| WO2002083139A1 (en) | 2001-04-10 | 2002-10-24 | Merck & Co., Inc. | Inhibitors of akt activity |
| US6958334B2 (en) | 2001-04-10 | 2005-10-25 | Merck & Co., Inc. | Inhibitors of Akt activity |
| AU2002251266A1 (en) | 2001-04-10 | 2002-10-28 | Merck Sharp And Dohme Limited | Inhibitors of akt activity |
| DE60315876T2 (de) * | 2002-11-28 | 2008-05-21 | Neurosearch A/S | Verfahren zum screening für verbindungen mit sedativer oder anxiolytischer potenz |
| WO2006061428A2 (en) * | 2004-12-10 | 2006-06-15 | Universität Zürich | Gaba-a alpha 2 and alpha 3 receptor agonists for treating neuropathic, inflammatory and migraine associated pain |
| EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
| EP2275095A3 (en) | 2005-08-26 | 2011-08-17 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| CA2625153A1 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| CA2625210A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| US7678808B2 (en) | 2006-05-09 | 2010-03-16 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
| JP2009536669A (ja) | 2006-05-09 | 2009-10-15 | ブレインセルス，インコーポレイティド | アンジオテンシン調節による神経新生 |
| AU2007292848A1 (en) | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| BRPI0912928A2 (pt) | 2008-08-29 | 2015-08-04 | Concert Pharmaceuticals Inc | "composto, e, composição isenta de pirogênio" |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| WO2011005520A1 (en) | 2009-06-23 | 2011-01-13 | Concert Pharmaceuticals, Inc. | Deuterium-modified triazolo-pyridazine derivatives as gaba-a receptor modulators |
| WO2011047315A1 (en) | 2009-10-15 | 2011-04-21 | Concert Pharmaceuticals, Inc. | Subsitituted benzimidazoles |
| WO2013170241A1 (en) * | 2012-05-11 | 2013-11-14 | Concert Pharmaceuticals, Inc. | Polymorphs of 7-(tert-butyl-d9)-3-(2,5-difluorophenyl)-6-((1-methyl-1h-1,2,4-triazol-5-yl)methoxy)-[1,2,4]triazolol[4,3b]pyridazine |
| US20150099753A1 (en) * | 2012-05-11 | 2015-04-09 | Concert Pharmaceuticals Inc. | Form 5 polymorph of 7-(tert-butyl-d9)-3-(2,5-difluorophenyl)-6-((1-methyl-1h-1,2,4-triazol-5-yl)methoxy)-[1,2,4]triazolo[4,3-b]pyridazine |
| JP2015516440A (ja) * | 2012-05-11 | 2015-06-11 | コンサート ファーマシューティカルズ インコーポレイテッド | ７−（ｔｅｒｔ−ブチル−ｄ９）−３−（２，５−ジフルオロフェニル）−６−（（１−メチル−１Ｈ−１，２，４−トリアゾール−５−イル）メトキシ）−［１，２，４］トリアゾロ［４，３−ｂ］ピリダジンの２型多形 |
| WO2015095549A1 (en) * | 2013-12-18 | 2015-06-25 | Concert Pharmaceuticals, Inc. | Dosage regimen for gabaa receptor subtype selective drug |
| IL281335B2 (en) | 2018-09-13 | 2024-07-01 | Saniona As | A gabaa receptor ligand |
| AU2023258030A1 (en) * | 2022-04-20 | 2024-10-17 | Engrail Therapeutics, Inc. | Gabaa receptor modulator salts, particles, and uses thereof |
| CN115837022B (zh) * | 2023-02-20 | 2023-04-25 | 中山大学附属第八医院（深圳福田） | 1,2,4三唑并4,3-b哒嗪衍生物在制备抗衰老药物中的应用 |
| WO2025141131A1 (en) | 2023-12-27 | 2025-07-03 | Saniona A/S | A gabaa receptor ligand and the use thereof in medicine, in particular in the treatment of epilepsy |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4216905B2 (ja) * | 1996-07-25 | 2009-01-28 | メルク シヤープ エンド ドーム リミテツド | Ｇａｂａ受容体に対するリガンドとしての置換トリアゾローピリダジン誘導体 |
-
2000
- 2000-01-19 ES ES00900748T patent/ES2232416T3/es not_active Expired - Lifetime
- 2000-01-19 AT AT00900748T patent/ATE284403T1/de not_active IP Right Cessation
- 2000-01-19 US US09/890,000 patent/US6500828B1/en not_active Expired - Fee Related
- 2000-01-19 DE DE60016566T patent/DE60016566T2/de not_active Expired - Fee Related
- 2000-01-19 EP EP00900748A patent/EP1149102B1/en not_active Expired - Lifetime
- 2000-01-19 CA CA002359008A patent/CA2359008C/en not_active Expired - Fee Related
- 2000-01-19 AU AU30669/00A patent/AU772947B2/en not_active Ceased
- 2000-01-19 WO PCT/GB2000/000183 patent/WO2000044752A1/en not_active Ceased
- 2000-01-19 JP JP2000596008A patent/JP2002535407A/ja not_active Withdrawn
-
2002
- 2002-12-20 US US10/324,968 patent/US20030158203A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2002535407A5 (enExample) | ||
| JP2004531563A5 (enExample) | ||
| CN110049987B (zh) | 制备化合物及其盐的方法 | |
| RU2000104863A (ru) | Производные 1,2,4-триазоло[4,3-b]пиридо[3,2-d]пиридазина и фармацевтические композиции, содержащие их | |
| JP2006513268A5 (ja) | アンタゴニスト活性を有するベンゾアゾリルピペラジン誘導体 | |
| RU2000113729A (ru) | Гетероциклические соединения для ингибирования секреции желудочной кислоты, способы их получения и их фармацевтические компоозиции | |
| JP2004514663A5 (enExample) | ||
| JP2003128673A5 (enExample) | ||
| JP2003532731A5 (enExample) | ||
| JP2003516363A (ja) | 勃起機能不全の処置のためのホスホジエステラーゼインヒビターの経粘膜投与 | |
| RU2006144075A (ru) | ДИФЕНИЛИМИДАЗОПИРИМИДИН И -ИМИДАЗОЛАМИНЫ КАК ИНГИБИТОРЫ β-СЕКРЕТАЗЫ | |
| JP2003531210A5 (enExample) | ||
| JP2004517070A5 (enExample) | ||
| JP2005047930A5 (enExample) | ||
| JP2008518890A5 (enExample) | ||
| JP2001525359A5 (enExample) | ||
| JP2007507494A5 (enExample) | ||
| JP2008509187A5 (enExample) | ||
| JP2008001722A5 (enExample) | ||
| JP2003507479A5 (enExample) | ||
| JP2002518502A5 (enExample) | ||
| JP2002527474A5 (ja) | 躁病および双極性障害の治療のための医薬 | |
| CA2617817A1 (en) | Thiazole derivatives for treating or preventing sleep disorders | |
| JP2005530779A5 (enExample) | ||
| MY124341A (en) | A substituted triazolo-pyridazine derivative, pharmaceutical compositions made therefrom |