JP2002533133A5 - - Google Patents
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- JP2002533133A5 JP2002533133A5 JP2000591212A JP2000591212A JP2002533133A5 JP 2002533133 A5 JP2002533133 A5 JP 2002533133A5 JP 2000591212 A JP2000591212 A JP 2000591212A JP 2000591212 A JP2000591212 A JP 2000591212A JP 2002533133 A5 JP2002533133 A5 JP 2002533133A5
- Authority
- JP
- Japan
- Prior art keywords
- mutant
- aspergillus
- toxin
- polypeptide
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 241000228212 Aspergillus Species 0.000 description 15
- 238000000034 method Methods 0.000 description 15
- 108700012359 toxins Proteins 0.000 description 15
- 229920001184 polypeptide Polymers 0.000 description 12
- 108090000765 processed proteins & peptides Proteins 0.000 description 12
- 102000004196 processed proteins & peptides Human genes 0.000 description 12
- 239000003053 toxin Substances 0.000 description 10
- 231100000765 toxin Toxicity 0.000 description 9
- 239000005409 aflatoxin Substances 0.000 description 6
- 108091028043 Nucleic acid sequence Proteins 0.000 description 5
- 150000007523 nucleic acids Chemical group 0.000 description 5
- 108090000623 proteins and genes Proteins 0.000 description 5
- 229960004799 tryptophan Drugs 0.000 description 5
- 229930195730 Aflatoxin Natural products 0.000 description 4
- XWIYFDMXXLINPU-UHFFFAOYSA-N Aflatoxin G Chemical compound O=C1OCCC2=C1C(=O)OC1=C2C(OC)=CC2=C1C1C=COC1O2 XWIYFDMXXLINPU-UHFFFAOYSA-N 0.000 description 4
- 239000012634 fragment Substances 0.000 description 4
- WBLZUCOIBUDNBV-UHFFFAOYSA-N 3-nitropropanoic acid Chemical compound OC(=O)CC[N+]([O-])=O WBLZUCOIBUDNBV-UHFFFAOYSA-N 0.000 description 3
- VWDXGKUTGQJJHJ-UHFFFAOYSA-N Catenarin Natural products C1=C(O)C=C2C(=O)C3=C(O)C(C)=CC(O)=C3C(=O)C2=C1O VWDXGKUTGQJJHJ-UHFFFAOYSA-N 0.000 description 3
- CNZIQHGDUXRUJS-UHFFFAOYSA-N Cyclopiazonic acid Natural products CC(=C/1C(=O)C2C3C(Cc4cccc5[nH]cc3c45)C(C)(C)N2C1=O)O CNZIQHGDUXRUJS-UHFFFAOYSA-N 0.000 description 3
- 239000010282 Emodin Substances 0.000 description 3
- RBLJKYCRSCQLRP-UHFFFAOYSA-N Emodin-dianthron Natural products O=C1C2=CC(C)=CC(O)=C2C(=O)C2=C1CC(=O)C=C2O RBLJKYCRSCQLRP-UHFFFAOYSA-N 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- YOOXNSPYGCZLAX-UHFFFAOYSA-N Helminthosporin Natural products C1=CC(O)=C2C(=O)C3=CC(C)=CC(O)=C3C(=O)C2=C1O YOOXNSPYGCZLAX-UHFFFAOYSA-N 0.000 description 3
- RNCGDQLZIATDOU-UHFFFAOYSA-N Malformin Chemical compound N1C(=O)C(C(C)CC)NC(=O)C(CC(C)C)NC(=O)C(C(C)C)NC(=O)C2CSSCC1C(=O)N2 RNCGDQLZIATDOU-UHFFFAOYSA-N 0.000 description 3
- NTGIIKCGBNGQAR-UHFFFAOYSA-N Rheoemodin Natural products C1=C(O)C=C2C(=O)C3=CC(O)=CC(O)=C3C(=O)C2=C1O NTGIIKCGBNGQAR-UHFFFAOYSA-N 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- CNZIQHGDUXRUJS-DQYPLSBCSA-N alpha-cyclopiazonic acid Natural products CC(O)=C1C(=O)[C@@H]2[C@@H]3[C@@H](Cc4cccc5[nH]cc3c45)C(C)(C)N2C1=O CNZIQHGDUXRUJS-DQYPLSBCSA-N 0.000 description 3
- ZKSIPEYIAHUPNM-ZEQRLZLVSA-N butobendine Chemical compound C([C@H](CC)N(C)CCN(C)[C@@H](CC)COC(=O)C=1C=C(OC)C(OC)=C(OC)C=1)OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 ZKSIPEYIAHUPNM-ZEQRLZLVSA-N 0.000 description 3
- RHMXXJGYXNZAPX-UHFFFAOYSA-N emodin Chemical compound C1=C(O)C=C2C(=O)C3=CC(C)=CC(O)=C3C(=O)C2=C1O RHMXXJGYXNZAPX-UHFFFAOYSA-N 0.000 description 3
- VASFLQKDXBAWEL-UHFFFAOYSA-N emodin Natural products OC1=C(OC2=C(C=CC(=C2C1=O)O)O)C1=CC=C(C=C1)O VASFLQKDXBAWEL-UHFFFAOYSA-N 0.000 description 3
- 229940088598 enzyme Drugs 0.000 description 3
- BEJNERDRQOWKJM-UHFFFAOYSA-N kojic acid Chemical compound OCC1=CC(=O)C(O)=CO1 BEJNERDRQOWKJM-UHFFFAOYSA-N 0.000 description 3
- 229960004705 kojic acid Drugs 0.000 description 3
- WZNJWVWKTVETCG-UHFFFAOYSA-N kojic acid Natural products OC(=O)C(N)CN1C=CC(=O)C(O)=C1 WZNJWVWKTVETCG-UHFFFAOYSA-N 0.000 description 3
- 229930191655 malformin Natural products 0.000 description 3
- 229930183344 ochratoxin Natural products 0.000 description 3
- PKUBGLYEOAJPEG-UHFFFAOYSA-N physcion Natural products C1=C(C)C=C2C(=O)C3=CC(C)=CC(O)=C3C(=O)C2=C1O PKUBGLYEOAJPEG-UHFFFAOYSA-N 0.000 description 3
- 101100462165 Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167) omtA gene Proteins 0.000 description 2
- 240000006439 Aspergillus oryzae Species 0.000 description 2
- 101100215645 Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) aflP gene Proteins 0.000 description 2
- 241001136487 Eurotium Species 0.000 description 2
- 241000130738 Hemicarpenteles Species 0.000 description 2
- 108091005804 Peptidases Proteins 0.000 description 2
- 239000004365 Protease Substances 0.000 description 2
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 2
- 101150118680 aflR gene Proteins 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000002243 precursor Substances 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- HCUOEKSZWPGJIM-YBRHCDHNSA-N (e,2e)-2-hydroxyimino-6-methoxy-4-methyl-5-nitrohex-3-enamide Chemical compound COCC([N+]([O-])=O)\C(C)=C\C(=N/O)\C(N)=O HCUOEKSZWPGJIM-YBRHCDHNSA-N 0.000 description 1
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 1
- 108010011619 6-Phytase Proteins 0.000 description 1
- 102000004400 Aminopeptidases Human genes 0.000 description 1
- 108090000915 Aminopeptidases Proteins 0.000 description 1
- 239000004382 Amylase Substances 0.000 description 1
- 108010065511 Amylases Proteins 0.000 description 1
- 102000013142 Amylases Human genes 0.000 description 1
- 101710152845 Arabinogalactan endo-beta-1,4-galactanase Proteins 0.000 description 1
- 235000002247 Aspergillus oryzae Nutrition 0.000 description 1
- 101100162199 Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) aflC gene Proteins 0.000 description 1
- 101100162200 Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) aflD gene Proteins 0.000 description 1
- 101100162203 Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) aflG gene Proteins 0.000 description 1
- 101100029917 Bacillus subtilis (strain 168) pksL gene Proteins 0.000 description 1
- 102100032487 Beta-mannosidase Human genes 0.000 description 1
- 102000005367 Carboxypeptidases Human genes 0.000 description 1
- 108010006303 Carboxypeptidases Proteins 0.000 description 1
- 102000016938 Catalase Human genes 0.000 description 1
- 108010053835 Catalase Proteins 0.000 description 1
- 102000030523 Catechol oxidase Human genes 0.000 description 1
- 108010031396 Catechol oxidase Proteins 0.000 description 1
- 108010059892 Cellulase Proteins 0.000 description 1
- 108010022172 Chitinases Proteins 0.000 description 1
- 102000012286 Chitinases Human genes 0.000 description 1
- 229920000858 Cyclodextrin Polymers 0.000 description 1
- 108010053770 Deoxyribonucleases Proteins 0.000 description 1
- 102000016911 Deoxyribonucleases Human genes 0.000 description 1
- 101100272070 Dothistroma septosporum (strain NZE10 / CBS 128990) avnA gene Proteins 0.000 description 1
- 101710147028 Endo-beta-1,4-galactanase Proteins 0.000 description 1
- 102000005593 Endopeptidases Human genes 0.000 description 1
- 108010059378 Endopeptidases Proteins 0.000 description 1
- 108090000371 Esterases Proteins 0.000 description 1
- 102000018389 Exopeptidases Human genes 0.000 description 1
- 108010091443 Exopeptidases Proteins 0.000 description 1
- 108010073178 Glucan 1,4-alpha-Glucosidase Proteins 0.000 description 1
- 102100022624 Glucoamylase Human genes 0.000 description 1
- 108010055629 Glucosyltransferases Proteins 0.000 description 1
- 102000000340 Glucosyltransferases Human genes 0.000 description 1
- 102000009127 Glutaminase Human genes 0.000 description 1
- 108010073324 Glutaminase Proteins 0.000 description 1
- 108010029541 Laccase Proteins 0.000 description 1
- 108090001060 Lipase Proteins 0.000 description 1
- 239000004367 Lipase Substances 0.000 description 1
- 102000004882 Lipase Human genes 0.000 description 1
- 108090000856 Lyases Proteins 0.000 description 1
- 102000004317 Lyases Human genes 0.000 description 1
- 102100024295 Maltase-glucoamylase Human genes 0.000 description 1
- 108010054377 Mannosidases Proteins 0.000 description 1
- 102000001696 Mannosidases Human genes 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- 102000004020 Oxygenases Human genes 0.000 description 1
- 108090000417 Oxygenases Proteins 0.000 description 1
- 101150078289 PKSA gene Proteins 0.000 description 1
- 102000003992 Peroxidases Human genes 0.000 description 1
- 108010059820 Polygalacturonase Proteins 0.000 description 1
- 102000006382 Ribonucleases Human genes 0.000 description 1
- 108010083644 Ribonucleases Proteins 0.000 description 1
- 108010030291 alpha-Galactosidase Proteins 0.000 description 1
- 102000005840 alpha-Galactosidase Human genes 0.000 description 1
- 108010028144 alpha-Glucosidases Proteins 0.000 description 1
- 150000001413 amino acids Chemical group 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- 108010051210 beta-Fructofuranosidase Proteins 0.000 description 1
- 108010005774 beta-Galactosidase Proteins 0.000 description 1
- 102000005936 beta-Galactosidase Human genes 0.000 description 1
- 108010047754 beta-Glucosidase Proteins 0.000 description 1
- 102000006995 beta-Glucosidase Human genes 0.000 description 1
- 108010055059 beta-Mannosidase Proteins 0.000 description 1
- 108010089934 carbohydrase Proteins 0.000 description 1
- 229940106157 cellulase Drugs 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 108010005400 cutinase Proteins 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 108010000165 exo-1,3-alpha-glucanase Proteins 0.000 description 1
- 108010093305 exopolygalacturonase Proteins 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000001573 invertase Substances 0.000 description 1
- 235000011073 invertase Nutrition 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 235000019421 lipase Nutrition 0.000 description 1
- 108010087558 pectate lyase Proteins 0.000 description 1
- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- 229940085127 phytase Drugs 0.000 description 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK199801726 | 1998-12-23 | ||
| DKPA199801726 | 1998-12-23 | ||
| DK199900745 | 1999-05-27 | ||
| DKPA199900745 | 1999-05-27 | ||
| PCT/DK1999/000726 WO2000039322A1 (en) | 1998-12-23 | 1999-12-22 | Methods for producing polypeptides in aspergillus mutant cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011103808A Division JP5453343B2 (ja) | 1998-12-23 | 2011-05-06 | アスペルギルス変異体細胞におけるポリペプチドの生産方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002533133A JP2002533133A (ja) | 2002-10-08 |
| JP2002533133A5 true JP2002533133A5 (https=) | 2007-02-15 |
Family
ID=26064565
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000591212A Withdrawn JP2002533133A (ja) | 1998-12-23 | 1999-12-22 | アスペルギルス変異体細胞におけるポリペプチドの生産方法 |
| JP2011103808A Expired - Lifetime JP5453343B2 (ja) | 1998-12-23 | 2011-05-06 | アスペルギルス変異体細胞におけるポリペプチドの生産方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011103808A Expired - Lifetime JP5453343B2 (ja) | 1998-12-23 | 2011-05-06 | アスペルギルス変異体細胞におけるポリペプチドの生産方法 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1141371B1 (https=) |
| JP (2) | JP2002533133A (https=) |
| CN (1) | CN100529096C (https=) |
| AT (1) | ATE414782T1 (https=) |
| AU (1) | AU1774000A (https=) |
| DE (1) | DE69939947D1 (https=) |
| DK (1) | DK1141371T3 (https=) |
| ES (1) | ES2317706T3 (https=) |
| WO (1) | WO2000039322A1 (https=) |
Families Citing this family (83)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003206684A1 (en) * | 2002-02-20 | 2003-09-09 | Novozymes A/S | Plant polypeptide production |
| US7396670B2 (en) | 2002-10-11 | 2008-07-08 | Novozymes A/S | Asparaginases and method of preparing a heat-treated product |
| WO2004090549A1 (en) * | 2003-04-11 | 2004-10-21 | Novozymes A/S | Method of screening for secreted glycosylated polypeptides |
| DK1620551T3 (da) | 2003-04-28 | 2014-01-13 | Chr Hansen As | Phospholipase og fremgangsmåde til fremstilling deraf |
| ATE516347T1 (de) | 2003-10-23 | 2011-07-15 | Novozymes As | Protease mit verbesserter stabilität in detergentien |
| WO2006053565A2 (en) | 2004-11-19 | 2006-05-26 | Novozymes A/S | Polypeptides having antimicrobial activity and polynucleotides encoding same |
| EP1831384B1 (en) | 2004-12-22 | 2015-08-12 | Novozymes A/S | Polypeptides having glucoamylase activity and polynucleotides encoding same |
| US7888489B2 (en) | 2005-01-24 | 2011-02-15 | Dsm Ip Assets B.V. | Method for producing a compound of interest in a filamentous fungal cell |
| EP1739428A1 (en) * | 2005-07-01 | 2007-01-03 | Institut Pasteur | In vitro diagnostic method and kit for an aspergillus infection |
| EP1941025B1 (en) | 2005-10-17 | 2011-06-29 | Novozymes A/S | Use of fungal mutants for expression of antibodies |
| WO2008000632A1 (en) | 2006-06-29 | 2008-01-03 | Dsm Ip Assets B.V. | A method for achieving improved polypeptide expression |
| EP2059590B1 (en) | 2006-07-14 | 2014-12-31 | Novozymes, Inc. | Methods for producing secreted polypeptides having biological activity |
| WO2009051152A1 (ja) * | 2007-10-19 | 2009-04-23 | Noda Institute For Scientific Research | ポリケタイドシンターゼ・ノンリボゾーマルペプチドシンテターゼ遺伝子 |
| EP2857515B1 (en) | 2008-11-20 | 2018-02-21 | Novozymes Inc. | Polypeptides having amylolytic enhancing activity and polynucleotides encoding same |
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| EP2421986A1 (en) | 2009-04-22 | 2012-02-29 | DSM IP Assets B.V. | Process for the production of a recombinant polypeptide of interest |
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| EP3293264A1 (en) | 2009-07-22 | 2018-03-14 | DSM IP Assets B.V. | Improved host cell for the production of a compound of interest |
| US8586829B2 (en) | 2009-09-30 | 2013-11-19 | Novozymes A/S | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
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| US9267125B2 (en) | 2009-11-06 | 2016-02-23 | Novozymes, Inc. | Polypeptides having cellobiohydrolase activity and polynucleotides encoding same |
| US9133448B2 (en) | 2010-02-11 | 2015-09-15 | Dsm Ip Assets B.V. | Polypeptide having cellobiohydrolase activity and uses thereof |
| EA201201125A1 (ru) | 2010-02-11 | 2013-03-29 | ДСМ АйПи АССЕТС Б.В. | Клетка-хозяин, способная продуцировать ферменты, пригодные для деградации лигноцеллюлозного материала |
| WO2011161208A1 (en) | 2010-06-25 | 2011-12-29 | Novozymes A/S | Polynucleotides having promoter activity |
| CN103068988A (zh) | 2010-06-25 | 2013-04-24 | 诺维信公司 | 具有启动子活性的多核苷酸 |
| CN103068978B (zh) | 2010-06-25 | 2017-01-18 | 诺维信公司 | 具有前导序列功能的多核苷酸 |
| DK2588603T3 (en) | 2010-06-29 | 2017-07-03 | Dsm Ip Assets Bv | POLYPEPTIDE THAT HAS OR CONTRIBUTES TO CARBOHYDRATE MATERIAL DEGRADING ACTIVITIES AND APPLICATIONS THEREOF |
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| WO2012000886A1 (en) | 2010-06-29 | 2012-01-05 | Dsm Ip Assets B.V. | Polypeptide having beta-glucosidase activity and uses thereof |
| EP2588604B1 (en) | 2010-06-30 | 2016-06-29 | Novozymes, Inc. | Polypeptides having beta-glucosidase activity and polynucleotides encoding same |
| AU2011273351A1 (en) | 2010-07-01 | 2013-01-17 | Dsm Ip Assets B.V. | A method for the production of a compound of interest |
| BR112013002979A2 (pt) | 2010-08-12 | 2016-06-07 | Novozymes Inc | composição, e, método para degradar ou converter um material celulósico, para produzir um produto de fermentação, e para fermentar um material celulósico. |
| US9187742B2 (en) | 2010-08-30 | 2015-11-17 | Novozymes, Inc. | Polypeptides having cellobiohydrolase activity and polynucleotides encoding same |
| US9267126B2 (en) | 2010-08-30 | 2016-02-23 | Novozymes, Inc. | Polypeptides having endoglucanase activity and polynucleotides encoding same |
| BR112013009026A2 (pt) | 2010-11-12 | 2016-07-12 | Novozymes Inc | polipeptídeo isolado, célula hospedeira recombinante, métodos para produzir um polipeptídeo, um mutante de uma célula precursora, uma proteína, e um produto de fermentação, para inibir a expressão de um polipeptídeo, para degradar ou converter um material celulósico, e método para fermentar um material celulósico, planta transgênica, parte de planta ou célula de planta, molécula de rna inibidora de filamento duplo, polinucleotídeo isolado, e, formulação de caldo integral ou composição de cultura de célula |
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| MX2013007720A (es) | 2011-01-26 | 2013-08-09 | Novozymes As | Polipeptidos que tienen actividad celobiohidrolasa y polinucleotidos que codifican para los mismos. |
| EP2668270B1 (en) | 2011-01-26 | 2018-11-21 | Novozymes A/S | Polypeptides having cellobiohydrolase activity and polynucleotides encoding same |
| US8759023B2 (en) | 2011-01-26 | 2014-06-24 | Novozymes Inc. | Polypeptides having cellobiohydrolase activity and polynucleotides encoding same |
| CN103608461B (zh) | 2011-03-09 | 2016-08-03 | 诺维信公司 | 增加多肽的纤维素分解增强活性的方法 |
| EP2702153B1 (en) | 2011-04-28 | 2018-12-12 | Novozymes, Inc. | Polypeptides having endoglucanase activity and polynucleotides encoding same |
| DK2702162T3 (da) | 2011-04-29 | 2020-05-18 | Novozymes Inc | Fremgangsmåder til forbedring af nedbrydningen eller omdannelsen af celluloseholdigt materiale |
| EP2527448A1 (en) | 2011-05-23 | 2012-11-28 | Novozymes A/S | Simultaneous site-specific integrations of multiple gene-copies in filamentous fungi |
| CN102321700A (zh) * | 2011-08-03 | 2012-01-18 | 无锡赛德生物工程有限公司 | 一种曲酸发酵工艺及发酵设备 |
| US9663772B2 (en) | 2011-08-24 | 2017-05-30 | Novozymes, Inc. | Aspergillus fumigatus cellulolytic enzyme compositions and uses thereof |
| WO2013064075A1 (en) | 2011-10-31 | 2013-05-10 | Novozymes, Inc. | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| US10351834B2 (en) | 2011-11-21 | 2019-07-16 | Novozymes, Inc. | GH61 polypeptide variants and polynucleotides encoding same |
| US10227579B2 (en) | 2012-04-27 | 2019-03-12 | Novozymes A/S | GH61 polypeptide variants and polynucleotides encoding same |
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| WO2014092832A2 (en) | 2012-09-19 | 2014-06-19 | Novozymes, Inc. | Methods for enhancing the degradation or conversion of cellulosic material |
| EP3586610B1 (en) | 2012-10-08 | 2024-09-25 | Novozymes A/S | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| WO2014066141A2 (en) | 2012-10-24 | 2014-05-01 | Novozymes A/S | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| BR112015013421A2 (pt) | 2012-12-14 | 2017-11-14 | Novozymes As E Novozymes Inc | célula hospedeira microbiana transgênica, polipeptídeo isolado, métodos de produção de um polipeptídeo e de uma proteína, processos de degradação de um material celulósico, de produção de um produto de fermentação e de fermentação de um material celulósico, construção de ácido nucleico ou vetor de expressão, polipeptídeo isolado, e polinucleotídeo isolado |
| CN105164254B (zh) | 2013-03-08 | 2019-06-28 | 诺维信公司 | 纤维二糖水解酶变体和编码它们的多核苷酸 |
| DK2994529T3 (en) | 2013-05-10 | 2019-03-04 | Novozymes As | Polypeptides with xylanase activity and polynucleotides encoding them |
| EP3594335B1 (en) | 2014-09-05 | 2024-05-01 | Novozymes A/S | Carbohydrate binding module variants and polynucleotides encoding same |
| MX383142B (es) | 2014-12-19 | 2025-03-13 | Novozymes As | Composiciones que comprenden polipéptidos que tienen actividad xilanasa y polipéptidos que tienen actividad arabinofuranosidasa. |
| US10557127B2 (en) | 2015-02-24 | 2020-02-11 | Novozymes A/S | Cellobiohydrolase variants and polynucleotides encoding same |
| BR112017021489A2 (pt) | 2015-05-27 | 2018-07-03 | Novozymes A/S | polipeptídeo tendo atividade de celobio-hidrolase, composição, formulação de caldo inteiro ou composição de cultura de células, polinucleotídeo, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, métodos de produção do polipeptídeo. |
| US10479984B2 (en) | 2015-09-22 | 2019-11-19 | Novozymes A/S | Polypeptides having cellobiohydrolase activity and polynucleotides encoding same |
| US11242507B2 (en) * | 2017-06-07 | 2022-02-08 | Ptt Global Chemical Public Company Limited | Mutant strain Aspergillus aculeatus for producing cellulase and xylanase and preparation method thereof |
| MY208100A (en) | 2017-08-25 | 2025-04-15 | Novozymes As | Enzyme assisted crude palm oil extraction |
| DK3775222T5 (da) | 2018-03-26 | 2024-08-19 | Novozymes As | Chaperoneproteiner fra svampe |
| CN108753748B (zh) * | 2018-06-08 | 2021-12-10 | 中国中医科学院中药研究所 | 大黄素糖基转移酶蛋白FtUGT75R2及其编码基因与应用 |
| CN108795903B (zh) * | 2018-06-08 | 2020-12-15 | 南京林业大学 | 一种高酶活淀粉酶的表达方法 |
| CN108823178B (zh) * | 2018-06-08 | 2021-12-10 | 中国中医科学院中药研究所 | 大黄素糖基转移酶蛋白FtUGT73BE5及其编码基因与应用 |
| BR112021011384A2 (pt) | 2018-12-12 | 2022-05-17 | Novozymes As | Polipeptídeo isolado, composição de enzimas, formulação de caldo inteiro ou composição de cultura de células, polinucleotídeo isolado, célula hospedeira recombinante, método de produção de um polipeptídeo, planta, parte da planta ou célula da planta transgênica, e, processos para degradação de um material celulósico ou hemicelulósico, para produção de um produto de fermentação e de fermentação de um material celulósico ou hemicelulósico |
| CN113316641B (zh) | 2018-12-21 | 2025-01-28 | 诺维信公司 | 串联蛋白表达 |
| CN110218750B (zh) * | 2019-04-24 | 2023-04-11 | 郑州轻工业学院 | 杂色曲霉菌株在发酵生产曲酸中应用 |
| CN110108874B (zh) * | 2019-04-30 | 2022-09-20 | 中国农业科学院油料作物研究所 | 快速检测环匹阿尼酸的胶体金免疫分析试纸条、制备及其应用 |
| CN110106152B (zh) * | 2019-04-30 | 2021-08-17 | 中国农业科学院油料作物研究所 | 杂交瘤细胞株ytt-2及其产生的抗环匹阿尼酸单克隆抗体 |
| CN114391038A (zh) | 2019-07-25 | 2022-04-22 | 诺维信公司 | 丝状真菌表达系统 |
| CN111139189B (zh) * | 2020-01-14 | 2022-04-19 | 浙江工业大学 | 曲霉wbx-38及其在生产环匹阿尼酸中的应用 |
| CN116024096B (zh) * | 2022-07-14 | 2025-06-03 | 浙江树人学院 | 泡盛曲霉sr3-28及其在从朱砂七提取大黄素中的应用 |
| CN120476196A (zh) | 2022-12-21 | 2025-08-12 | 诺维信公司 | 用于细胞分离的微生物蛋白酶 |
| CN116064437B (zh) * | 2023-02-20 | 2025-09-23 | 武汉轻工大学 | 用于降解黄曲霉毒素的复合酶制剂、复合酶制剂溶液及其制备方法和应用 |
| WO2025133003A2 (en) | 2023-12-19 | 2025-06-26 | 21St.Bio A/S | Non-animal bovine beta lactoglobulin |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2178007A1 (en) * | 1993-12-01 | 1995-06-08 | Randy M. Berka | Aspergillus expression system |
| CA2178008A1 (en) * | 1993-12-01 | 1995-06-08 | Randy M. Berka | Aspergillus foetidus expression system |
| JP4436934B2 (ja) * | 1996-09-13 | 2010-03-24 | ノボザイムス，インコーポレイティド | 変更された量のポリペプチドを生成するｄｎａ挿入突然変異を有する細胞 |
| EP0956338B1 (en) * | 1996-09-19 | 2005-12-21 | Novozymes A/S | Host cells and methods of producing proteins |
-
1999
- 1999-12-22 AU AU17740/00A patent/AU1774000A/en not_active Abandoned
- 1999-12-22 WO PCT/DK1999/000726 patent/WO2000039322A1/en not_active Ceased
- 1999-12-22 ES ES99960956T patent/ES2317706T3/es not_active Expired - Lifetime
- 1999-12-22 DE DE69939947T patent/DE69939947D1/de not_active Expired - Lifetime
- 1999-12-22 DK DK99960956T patent/DK1141371T3/da active
- 1999-12-22 CN CNB99815766XA patent/CN100529096C/zh not_active Expired - Lifetime
- 1999-12-22 EP EP99960956A patent/EP1141371B1/en not_active Expired - Lifetime
- 1999-12-22 AT AT99960956T patent/ATE414782T1/de active
- 1999-12-22 JP JP2000591212A patent/JP2002533133A/ja not_active Withdrawn
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2011
- 2011-05-06 JP JP2011103808A patent/JP5453343B2/ja not_active Expired - Lifetime
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