JP2002529705A5 - - Google Patents
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- Publication number
- JP2002529705A5 JP2002529705A5 JP2000580001A JP2000580001A JP2002529705A5 JP 2002529705 A5 JP2002529705 A5 JP 2002529705A5 JP 2000580001 A JP2000580001 A JP 2000580001A JP 2000580001 A JP2000580001 A JP 2000580001A JP 2002529705 A5 JP2002529705 A5 JP 2002529705A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- fragment
- antigen
- derivative
- aptamer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000012634 fragment Substances 0.000 description 49
- 238000000034 method Methods 0.000 description 37
- 108091023037 Aptamer Proteins 0.000 description 31
- 239000000427 antigen Substances 0.000 description 16
- 108091007433 antigens Proteins 0.000 description 16
- 102000036639 antigens Human genes 0.000 description 16
- 241000124008 Mammalia Species 0.000 description 15
- 239000002253 acid Substances 0.000 description 10
- 244000005700 microbiome Species 0.000 description 9
- 102000004169 proteins and genes Human genes 0.000 description 8
- 108090000623 proteins and genes Proteins 0.000 description 8
- 241000590002 Helicobacter pylori Species 0.000 description 7
- 108091028043 Nucleic acid sequence Proteins 0.000 description 7
- 230000015572 biosynthetic process Effects 0.000 description 7
- 229940037467 helicobacter pylori Drugs 0.000 description 6
- 239000000203 mixture Substances 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 5
- 239000006166 lysate Substances 0.000 description 5
- 108090000765 processed proteins & peptides Proteins 0.000 description 5
- 102100038222 60 kDa heat shock protein, mitochondrial Human genes 0.000 description 4
- 101710154868 60 kDa heat shock protein, mitochondrial Proteins 0.000 description 4
- 102000007456 Peroxiredoxin Human genes 0.000 description 4
- 108010046334 Urease Proteins 0.000 description 4
- 210000003608 fece Anatomy 0.000 description 4
- 108030002458 peroxiredoxin Proteins 0.000 description 4
- 101710087887 Alkyl hydroperoxide reductase C Proteins 0.000 description 3
- 101000609456 Beet necrotic yellow vein virus (isolate Japan/S) Protein P26 Proteins 0.000 description 3
- 108010004889 Heat-Shock Proteins Proteins 0.000 description 3
- 102000002812 Heat-Shock Proteins Human genes 0.000 description 3
- 238000004113 cell culture Methods 0.000 description 3
- 230000009918 complex formation Effects 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 210000001035 gastrointestinal tract Anatomy 0.000 description 3
- 210000004408 hybridoma Anatomy 0.000 description 3
- 230000000813 microbial effect Effects 0.000 description 3
- 238000009629 microbiological culture Methods 0.000 description 3
- 101710112984 20 kDa protein Proteins 0.000 description 2
- 241000589876 Campylobacter Species 0.000 description 2
- 238000002965 ELISA Methods 0.000 description 2
- 102000001390 Fructose-Bisphosphate Aldolase Human genes 0.000 description 2
- 108010068561 Fructose-Bisphosphate Aldolase Proteins 0.000 description 2
- 206010019375 Helicobacter infections Diseases 0.000 description 2
- 101710159910 Movement protein Proteins 0.000 description 2
- 101001086866 Sus scrofa Pulmonary surfactant-associated protein B Proteins 0.000 description 2
- 101710090398 Viral interleukin-10 homolog Proteins 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 210000000440 neutrophil Anatomy 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 238000003127 radioimmunoassay Methods 0.000 description 2
- 108091026890 Coding region Proteins 0.000 description 1
- 241000589989 Helicobacter Species 0.000 description 1
- 241001453258 Helicobacter hepaticus Species 0.000 description 1
- 241000186359 Mycobacterium Species 0.000 description 1
- 241000187479 Mycobacterium tuberculosis Species 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 238000003317 immunochromatography Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000001262 western blot Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98120687.3 | 1998-06-11 | ||
| EP98120517.2 | 1998-10-29 | ||
| EP98120517 | 1998-10-29 | ||
| EP98120687 | 1998-11-06 | ||
| PCT/EP1999/008212 WO2000026671A1 (de) | 1998-10-29 | 1999-10-29 | Nachweis von säure-resistenten mikroorganismen im stuhl |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002529705A JP2002529705A (ja) | 2002-09-10 |
| JP2002529705A5 true JP2002529705A5 (enExample) | 2006-12-21 |
Family
ID=26149749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000580001A Ceased JP2002529705A (ja) | 1998-10-29 | 1999-10-29 | 糞便中の耐酸性微生物を検出するための新規方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7122320B2 (enExample) |
| EP (2) | EP1734366A3 (enExample) |
| JP (1) | JP2002529705A (enExample) |
| AT (1) | ATE334395T1 (enExample) |
| AU (1) | AU1157100A (enExample) |
| DE (1) | DE59913716D1 (enExample) |
| DK (1) | DK1125130T3 (enExample) |
| ES (1) | ES2270638T3 (enExample) |
| WO (1) | WO2000026671A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1734366A3 (de) * | 1998-10-29 | 2007-11-07 | Oxoid (Ely) Limited | Neues Verfahren zum Nachweis von Säure-resistenten Mikroorganismen im Stuhl |
| EP1232392B2 (de) * | 1999-10-12 | 2014-04-02 | Oxoid (Ely) Limited | Verbessertes verfahren zum nachweis von säure-resistenten bakterien der gattung helicobacter im stuhl |
| JP3504633B2 (ja) | 1999-10-29 | 2004-03-08 | わかもと製薬株式会社 | ヘリコバクター・ピロリへの感染を判定する検査方法及び検査試薬 |
| EP1227159B1 (en) | 1999-10-29 | 2011-04-20 | Wakamoto Pharmaceutical Co., Ltd. | Monoclonal antibody, hybridoma, immunoassay method and diagnosis kit |
| DE60138981D1 (de) * | 2000-05-18 | 2009-07-30 | Meridian Bioscience Inc | Immunoassay für H. pylori in Fäkalienproben mit Hilfe von gattungsspezifischen Antikörpern |
| DE10043161A1 (de) * | 2000-09-01 | 2002-03-14 | Connex Ges Zur Optimierung Von | Lösung zur Aufbereitung von Stuhlproben für diagnostische Zwecke |
| BR0207068A (pt) * | 2001-01-26 | 2004-12-21 | Inhibitex Inc | Anticorpo monoclonal para a protéina clfa, anti-soro isolado, anticorpo isolado e anticorpo humanizado contendo o referido anticorpo, kit diagnóstico compreendendo o referido anticorpo, método para diagnóstico de uma infecção por s.aureus, composição farmacêutica para o tratamento ou prevenção da referida infecção, método para indução de de uma resposta imunológica, método para identificação de anticorpos monoclonais para a protéina clfa e fragmento ativo isolado a partir do domìnio a da protéina clfa do s.aureus |
| FI118061B (fi) | 2001-09-24 | 2007-06-15 | Beanor Oy | Menetelmä ja bioanturi analyysiä varten |
| FI115166B (fi) | 2001-12-31 | 2005-03-15 | Biofons Oy | Diagnostisia menetelmiä |
| US20040023415A1 (en) * | 2002-03-05 | 2004-02-05 | Konstantin Sokolov | Biospecific contrast agents |
| DE10219741A1 (de) * | 2002-05-02 | 2003-11-13 | Georg S Wengler | Verfahren zur Vorbehandlung von Stuhlproben |
| GB0210783D0 (en) * | 2002-05-10 | 2002-06-19 | Polonelli Luciano | Anti-microbial polypeptides |
| US20090191213A9 (en) | 2003-07-02 | 2009-07-30 | Novo Nordisk A/S | Compositions and methods for regulating NK cell activity |
| KR20060079180A (ko) * | 2003-07-02 | 2006-07-05 | 노보 노르디스크 에이/에스 | Ｎｋ 세포 활성을 조절하기 위한 조성물 및 방법 |
| DK2287195T3 (da) * | 2004-07-01 | 2019-08-19 | Innate Pharma | Pan-kir2dl nk-receptor-antistoffer og anvendelse heraf i diagnostik og terapi |
| DE602005026538D1 (de) * | 2004-07-01 | 2011-04-07 | Innate Pharma | An die rezeptoren kir2dl1, -2, -3, jedoch nicht kir2ds4, bindende antikörper und deren therapeutische verwendung |
| JP4625318B2 (ja) * | 2004-12-06 | 2011-02-02 | 財団法人野田産業科学研究所 | 相同組換え頻度が上昇した形質転換菌 |
| PL1836225T3 (pl) | 2005-01-06 | 2012-05-31 | Novo Nordisk As | Czynniki wiążące kir i sposoby ich stosowania |
| WO2009088460A2 (en) * | 2008-01-03 | 2009-07-16 | Ask Diagnostics, Inc. | Methods of diagnosing latent and active malignancies |
| US20110065086A1 (en) * | 2008-02-21 | 2011-03-17 | Otc Biotechnologies, Llc | Methods of producing homogeneous plastic-adherent aptamer-magnetic bead-fluorophore and other sandwich assays |
| CA2871081A1 (en) * | 2011-04-21 | 2012-10-26 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Peptide and conjugate vaccines for fungal infections |
| WO2016176176A1 (en) * | 2015-04-29 | 2016-11-03 | 3M Innovative Properties Company | Culture device for anaerobic microorganisms |
| CN109628457B (zh) * | 2019-02-03 | 2021-12-10 | 淮海工学院 | 单链dna核酸适配体及其筛选方法与用途 |
| CN110618270B (zh) * | 2019-09-10 | 2020-08-25 | 深圳市鸿美诊断技术有限公司 | 一种用于定量测定粪便中幽门螺杆菌抗原试剂的制备方法 |
| EP4204003A4 (en) * | 2020-08-28 | 2024-08-21 | Board of Regents, The University of Texas System | ANTIBODIES SPECIFIC TO CCL21 AND METHODS OF USE |
| TW202317188A (zh) * | 2021-06-22 | 2023-05-01 | 美商通用醫院公司 | 於癌症中治療靶向鈣黏蛋白11 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4879213A (en) * | 1986-12-05 | 1989-11-07 | Scripps Clinic And Research Foundation | Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse |
| JPS63273497A (ja) * | 1986-12-26 | 1988-11-10 | Meiji Seika Kaisha Ltd | 抗カンピロバクターモノクローナル抗体 |
| US5200344A (en) * | 1990-11-13 | 1993-04-06 | Blaser Martin J | Diagnostic testing for campylobacter jejuni or campylobacter coli infections using novel antigens |
| WO1996034624A1 (en) * | 1995-05-02 | 1996-11-07 | Institut Pasteur | Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions, and nucleic acid sequences encoding said polypeptides |
| GB2307987A (en) * | 1995-12-06 | 1997-06-11 | Univ Manchester | Epitopes of the urease of Helicobacter pylori as dignostic agents; pharmaceuticals comprising such epitopes or the antibodies thereto |
| US5716791A (en) * | 1996-05-09 | 1998-02-10 | Meridian Diagnostics, Inc. | Immunoassay for H. pylori in fecal specimens |
| US5932430A (en) * | 1996-05-09 | 1999-08-03 | Meridian Diagnostics, Inc. | Immunoassay for H. pylori in fecal specimens |
| US6383763B1 (en) * | 1996-07-26 | 2002-05-07 | Case Western Reserve University | Detection of mycobacteria |
| IT1289578B1 (it) * | 1996-12-06 | 1998-10-15 | Sanitaria Scaligera Spa | Immunopurificazione di un antigene dall'apparente peso molecolare di 16 +- 2 kda dell' helicobacter pylori e metodi per la sua |
| EP1734366A3 (de) * | 1998-10-29 | 2007-11-07 | Oxoid (Ely) Limited | Neues Verfahren zum Nachweis von Säure-resistenten Mikroorganismen im Stuhl |
-
1999
- 1999-10-29 EP EP06015257A patent/EP1734366A3/de not_active Withdrawn
- 1999-10-29 AU AU11571/00A patent/AU1157100A/en not_active Abandoned
- 1999-10-29 AT AT99971515T patent/ATE334395T1/de not_active IP Right Cessation
- 1999-10-29 DK DK99971515T patent/DK1125130T3/da active
- 1999-10-29 JP JP2000580001A patent/JP2002529705A/ja not_active Ceased
- 1999-10-29 DE DE59913716T patent/DE59913716D1/de not_active Expired - Lifetime
- 1999-10-29 EP EP99971515A patent/EP1125130B1/de not_active Expired - Lifetime
- 1999-10-29 WO PCT/EP1999/008212 patent/WO2000026671A1/de not_active Ceased
- 1999-10-29 ES ES99971515T patent/ES2270638T3/es not_active Expired - Lifetime
-
2001
- 2001-04-27 US US09/842,776 patent/US7122320B2/en not_active Expired - Lifetime
-
2006
- 2006-08-31 US US11/513,129 patent/US7736859B2/en not_active Expired - Fee Related
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