JP2002527387A - Ｐｕｆａサプリメント - Google Patents

Ｐｕｆａサプリメント

Info

Publication number
JP2002527387A
JP2002527387A JP2000575500A JP2000575500A JP2002527387A JP 2002527387 A JP2002527387 A JP 2002527387A JP 2000575500 A JP2000575500 A JP 2000575500A JP 2000575500 A JP2000575500 A JP 2000575500A JP 2002527387 A JP2002527387 A JP 2002527387A
Authority
JP
Japan
Prior art keywords
ara
dha
pregnant
woman
levels
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000575500A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002527387A5 (enExample
Inventor
イザベル・アントニア・マリア・ファン・ワーテルスホート
ヒューゴ・ストレークストラ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM BV
Original Assignee
DSM NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8235104&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2002527387(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by DSM NV filed Critical DSM NV
Publication of JP2002527387A publication Critical patent/JP2002527387A/ja
Publication of JP2002527387A5 publication Critical patent/JP2002527387A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Addiction (AREA)
  • Polymers & Plastics (AREA)
  • Psychiatry (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Animal Husbandry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Rheumatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Zoology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
JP2000575500A 1998-10-15 1999-10-15 Ｐｕｆａサプリメント Pending JP2002527387A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98308403.9 1998-10-15
EP98308403 1998-10-15
PCT/EP1999/007834 WO2000021524A1 (en) 1998-10-15 1999-10-15 Pufa supplements

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010268487A Division JP2011098966A (ja) 1998-10-15 2010-12-01 Ｐｕｆａサプリメント

Publications (2)

Publication Number Publication Date
JP2002527387A true JP2002527387A (ja) 2002-08-27
JP2002527387A5 JP2002527387A5 (enExample) 2006-12-07

Family

ID=8235104

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000575500A Pending JP2002527387A (ja) 1998-10-15 1999-10-15 Ｐｕｆａサプリメント
JP2010268487A Pending JP2011098966A (ja) 1998-10-15 2010-12-01 Ｐｕｆａサプリメント

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010268487A Pending JP2011098966A (ja) 1998-10-15 2010-12-01 Ｐｕｆａサプリメント

Country Status (13)

Country Link
US (2) US20070184090A1 (enExample)
EP (4) EP2308486A1 (enExample)
JP (2) JP2002527387A (enExample)
CN (3) CN1326344A (enExample)
AT (1) ATE361066T1 (enExample)
AU (2) AU775421B2 (enExample)
CA (2) CA2653503A1 (enExample)
DE (1) DE69935995T3 (enExample)
DK (1) DK1121115T4 (enExample)
ES (1) ES2284286T5 (enExample)
HK (1) HK1042441A1 (enExample)
NZ (1) NZ511071A (enExample)
WO (1) WO2000021524A1 (enExample)

Cited By (10)

* Cited by examiner, † Cited by third party
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JP2008504336A (ja) * 2004-07-01 2008-02-14 ネステク ソシエテ アノニム イヌ変形性関節症食餌製剤
JP2014513098A (ja) * 2011-04-26 2014-05-29 レトロトップ、 インコーポレイテッド 神経変性障害および筋疾患に関与するｐｕｆａ
US10052299B2 (en) 2009-10-30 2018-08-21 Retrotope, Inc. Alleviating oxidative stress disorders with PUFA derivatives
US10058522B2 (en) 2011-04-26 2018-08-28 Retrotope, Inc. Oxidative retinal diseases
US10058612B2 (en) 2011-04-26 2018-08-28 Retrotope, Inc. Impaired energy processing disorders and mitochondrial deficiency
US10154978B2 (en) 2011-04-26 2018-12-18 Retrotope, Inc. Disorders implicating PUFA oxidation
US11447441B2 (en) 2015-11-23 2022-09-20 Retrotope, Inc. Site-specific isotopic labeling of 1,4-diene systems
US11779910B2 (en) 2020-02-21 2023-10-10 Biojiva Llc Processes for isotopic modification of polyunsaturated fatty acids and derivatives thereof
US12109194B2 (en) 2021-02-05 2024-10-08 Biojiva Llc Synergistic combination therapy for treating ALS
US12673037B2 (en) 2021-02-05 2026-07-07 Biojiva Llc Methods of treating amyotrophic lateral sclerosis

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* Cited by examiner, † Cited by third party
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GB0016045D0 (en) 2000-06-29 2000-08-23 Laxdale Limited Therapeutic combinations of fatty acids
DK1911837T3 (da) 2000-09-28 2011-08-29 Bioriginal Food & Science Corp FAD5-2 fedtsyredesaturasefamiliemedlem og anvendelser deraf
CA2442692A1 (en) * 2001-03-30 2002-10-10 The Nisshin Oillio, Ltd. Bone metabolism improving agents
JP2003048831A (ja) 2001-08-02 2003-02-21 Suntory Ltd 脳機能の低下に起因する症状あるいは疾患の予防又は改善作用を有する組成物
AU778384B2 (en) * 2001-11-14 2004-12-02 Virtus Nutrition Llc Method for manufacturing fatty acid calcium salts from high glyceride content oils
KR102254453B1 (ko) * 2002-06-19 2021-05-21 디에스엠 아이피 어셋츠 비.브이. 미생물 세포와 미생물 오일용 파스퇴르살균 방법
KR101195574B1 (ko) * 2002-09-24 2012-10-30 산토리 홀딩스 가부시키가이샤 아라키돈산을 단독으로 또는 도코사헥사엔산과의 조합으로함유하는 인지 능력 향상용 조성물
US20070037885A1 (en) * 2003-04-25 2007-02-15 Sandra Edwards Biomass containing animal feed
US8633247B2 (en) 2003-08-11 2014-01-21 Hill's Pet Nutrition, Inc. Method for decreasing cartilage damage in dogs
US8633246B2 (en) 2003-08-11 2014-01-21 Hill's Pet Nutrition, Inc. Omega-3 fatty acids for osteoarthritis
EA200602014A1 (ru) 2004-04-30 2007-08-31 ВИРТУС НЬЮТРИШН ЭлЭлСи Синтез солей одновалентных и двухвалентных металлов полиненасыщенных жирных кислот
ES2253089B1 (es) * 2004-07-16 2007-08-16 Berthol Victor Laboratorios Ordesa, S.L. Complemento nutraceutico para la preparacion de leches infantiles.
JP2006083136A (ja) * 2004-09-17 2006-03-30 Suntory Ltd ストレスに起因する脳機能の低下およびそれに伴う症状あるいは疾患の予防又は改善作用を有する組成物
JP4993852B2 (ja) 2004-09-17 2012-08-08 サントリーホールディングス株式会社 ストレスに起因する行動異常を伴う症状あるいは疾患の予防又は改善作用を有する組成物
JP5967855B2 (ja) 2005-06-30 2016-08-10 サントリーホールディングス株式会社 日中活動量の低下および／又はうつ症状の改善作用を有する組成物
EP1772146A1 (en) * 2005-10-03 2007-04-11 Neuropharma, S.A. Polyunsaturated fatty acids as bace inhibitors
KR101578498B1 (ko) 2006-12-28 2015-12-18 산토리 홀딩스 가부시키가이샤 신경 재생제
US20090202672A1 (en) * 2008-02-11 2009-08-13 Monsanto Company Aquaculture feed, products, and methods comprising beneficial fatty acids
CN101259101B (zh) * 2008-04-17 2010-06-02 湖北福星生物科技有限公司 微米级花生四烯酸和二十二碳六烯酸乳状液及其制备方法
GB2460056A (en) * 2008-05-14 2009-11-18 Arab Science & Technology Foun Compositions comprising omega-6 fatty acids for use in treating schistosomiasis
EP2745706A1 (en) * 2012-12-24 2014-06-25 Abbott Laboratories, Inc. Methods for maintaining bone quality
BR112016014262B1 (pt) 2013-12-20 2022-04-05 MARA Renewables Corporation Método para recuperar lipídeos de uma população de micro-organismos
MA41611A (fr) * 2015-02-23 2018-01-02 Omthera Pharmaceuticals Inc Préparations en milli-capsules comprenant des acides gras polyinsaturés libres
US10851395B2 (en) 2016-06-10 2020-12-01 MARA Renewables Corporation Method of making lipids with improved cold flow properties
EP3559206B1 (en) 2016-12-22 2025-12-03 Mara Renewables Corporation Methods for producing biomass rich in dha, palmitic acid and protein using a eukaryotic microorganism
IL297000A (en) 2020-04-03 2022-12-01 Mara Renewables Corp Microbial oils with high levels of omega-3 fatty acids
WO2024050589A1 (en) * 2022-09-07 2024-03-14 Nourish Ingredients Pty Ltd Compositions and methods for producing meat-like aromas
WO2026020071A1 (en) * 2024-07-18 2026-01-22 Red Abbey Labs, Llc Autogenous therapeutic lipid carriers

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WO1998016119A1 (en) * 1996-10-11 1998-04-23 Suntory Limited Edible fats containing arachidonic acid and foods containing the same

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US6200624B1 (en) 1996-01-26 2001-03-13 Abbott Laboratories Enteral formula or nutritional supplement containing arachidonic and docosahexaenoic acids
DK0969728T4 (da) 1996-03-26 2012-11-19 Dsm Ip Assets Bv Sen tilsætning af PUFA ved fremstillingsproces for formulering til spædbørn
ES2177966T3 (es) 1996-03-26 2002-12-16 Dsm Nv Particulas de vehiculos solidos revestidas con acidos grasos poliinsaturados (pufa) para productos alimentarios.
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WO1998016119A1 (en) * 1996-10-11 1998-04-23 Suntory Limited Edible fats containing arachidonic acid and foods containing the same

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JP2008504336A (ja) * 2004-07-01 2008-02-14 ネステク ソシエテ アノニム イヌ変形性関節症食餌製剤
US11510888B2 (en) 2009-10-30 2022-11-29 Retrotope, Inc. Alleviating oxidative stress disorders with PUFA derivatives
US10052299B2 (en) 2009-10-30 2018-08-21 Retrotope, Inc. Alleviating oxidative stress disorders with PUFA derivatives
USRE49238E1 (en) 2009-10-30 2022-10-11 Retrotope, Inc. Alleviating oxidative stress disorders with PUFA derivatives
US10058612B2 (en) 2011-04-26 2018-08-28 Retrotope, Inc. Impaired energy processing disorders and mitochondrial deficiency
US10058522B2 (en) 2011-04-26 2018-08-28 Retrotope, Inc. Oxidative retinal diseases
US10154983B2 (en) 2011-04-26 2018-12-18 Retrotope, Inc. Neurodegenerative disorders and muscle diseases implicating PUFAs
US11241409B2 (en) 2011-04-26 2022-02-08 Retrotope, Inc. Neurodegenerative disorders and muscle diseases implicating PUFAs
US11285125B2 (en) 2011-04-26 2022-03-29 Retrotope, Inc. Oxidative retinal diseases
US12156860B2 (en) 2011-04-26 2024-12-03 Biojiva Llc Disorders implicating PUFA oxidation
JP2014513098A (ja) * 2011-04-26 2014-05-29 レトロトップ、 インコーポレイテッド 神経変性障害および筋疾患に関与するｐｕｆａ
US10154978B2 (en) 2011-04-26 2018-12-18 Retrotope, Inc. Disorders implicating PUFA oxidation
US11453637B2 (en) 2015-11-23 2022-09-27 Retrotope, Inc. Site-specific isotopic labeling of 1,4-diene systems
US12060324B2 (en) 2015-11-23 2024-08-13 Biojiva Llc Site-specific isotopic labeling of 1,4-diene systems
US11447441B2 (en) 2015-11-23 2022-09-20 Retrotope, Inc. Site-specific isotopic labeling of 1,4-diene systems
US11779910B2 (en) 2020-02-21 2023-10-10 Biojiva Llc Processes for isotopic modification of polyunsaturated fatty acids and derivatives thereof
US12109194B2 (en) 2021-02-05 2024-10-08 Biojiva Llc Synergistic combination therapy for treating ALS
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DK1121115T3 (da) 2007-07-02
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CN1326344A (zh) 2001-12-12
ATE361066T1 (de) 2007-05-15
CA2355341C (en) 2009-04-14
EP1121115A1 (en) 2001-08-08
EP2292223A1 (en) 2011-03-09
EP2308486A1 (en) 2011-04-13
DE69935995D1 (de) 2007-06-14
ES2284286T3 (es) 2007-11-01
HK1042441A1 (zh) 2002-08-16
CN101283807A (zh) 2008-10-15
CA2355341A1 (en) 2000-04-20
DK1121115T4 (da) 2011-01-10
AU2004224924A1 (en) 2004-11-25
ES2284286T5 (es) 2011-01-03
EP1121115B2 (en) 2010-08-18
NZ511071A (en) 2004-01-30
JP2011098966A (ja) 2011-05-19
US20090105342A1 (en) 2009-04-23
EP1121115B1 (en) 2007-05-02
DE69935995T2 (de) 2008-01-10
US20070184090A1 (en) 2007-08-09
AU1152000A (en) 2000-05-01
CA2653503A1 (en) 2000-04-20
AU775421B2 (en) 2004-07-29
WO2000021524A1 (en) 2000-04-20
AU2004224924B2 (en) 2008-02-28
DE69935995T3 (de) 2011-02-10

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