JP2002523106A - 誘導的発現系 - Google Patents
誘導的発現系Info
- Publication number
- JP2002523106A JP2002523106A JP2000567726A JP2000567726A JP2002523106A JP 2002523106 A JP2002523106 A JP 2002523106A JP 2000567726 A JP2000567726 A JP 2000567726A JP 2000567726 A JP2000567726 A JP 2000567726A JP 2002523106 A JP2002523106 A JP 2002523106A
- Authority
- JP
- Japan
- Prior art keywords
- expression system
- adenovirus vector
- receptor
- expression
- vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Obesity (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9810842A FR2782732A1 (fr) | 1998-08-28 | 1998-08-28 | Systeme d'expression inductible |
FR98/10842 | 1998-08-28 | ||
PCT/FR1999/002051 WO2000012741A2 (fr) | 1998-08-28 | 1999-08-27 | Systeme d'expression inductible |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2002523106A true JP2002523106A (ja) | 2002-07-30 |
Family
ID=9529972
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000567726A Pending JP2002523106A (ja) | 1998-08-28 | 1999-08-27 | 誘導的発現系 |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1108051A2 (fr) |
JP (1) | JP2002523106A (fr) |
AU (1) | AU5426299A (fr) |
CA (1) | CA2341775A1 (fr) |
FR (1) | FR2782732A1 (fr) |
WO (1) | WO2000012741A2 (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU3642601A (en) * | 1999-11-05 | 2001-05-30 | Avigen, Inc. | Ecdysone-inducible adeno-associated virus expression vectors |
ATE525091T1 (de) * | 2000-03-13 | 2011-10-15 | Engene Inc | Zusammensetzungen und verfahren zur regulierten proteinexpression im darm |
AU2003216407A1 (en) * | 2002-02-25 | 2003-09-09 | University Of Rochester | Dna construct for inducible expression of angiogenic protein and use thereof |
EP1531666B1 (fr) * | 2002-05-29 | 2013-10-23 | Regeneron Pharmaceuticals, Inc. | Systeme d'expression eucaryote inductible |
US8673589B2 (en) | 2002-05-29 | 2014-03-18 | Regeneron Pharmaceuticals, Inc. | Inducible eukaryotic expression system |
PL376397A1 (en) * | 2002-10-14 | 2005-12-27 | F.Hoffmann-La Roche Ag | Transplantable cell |
JP4842128B2 (ja) | 2003-07-21 | 2011-12-21 | トランジェーヌ、ソシエテ、アノニム | 新規多機能性サイトカイン |
NZ571965A (en) | 2006-03-30 | 2012-02-24 | Engene Inc | Chitosan-based nanoparticles and methods for transfecting gut cells in vivo |
EP3587455A1 (fr) | 2012-10-23 | 2020-01-01 | Emory University | Conjugués de gm-csf et d'il-4, compositions et procédés associés |
WO2016081927A2 (fr) * | 2014-11-21 | 2016-05-26 | University Of Florida Research Foundation, Inc. | Vecteurs viraux adéno-associés recombinés au génome modifié |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1309044C (fr) * | 1987-11-09 | 1992-10-20 | Toshiya Takano | Methode de production de genes etrangers |
FR2732348B1 (fr) * | 1995-03-31 | 1997-04-30 | Rhone Poulenc Rorer Sa | Systeme d'expression conditionnel |
FR2745008A1 (fr) * | 1996-02-20 | 1997-08-22 | Ass Pour Le Dev De La Rech En | Recepteur nucleaire de glucocorticoides modifie, fragments d'adn codant pour ledit recepteur et procedes dans lesquels ils sont mis en oeuvre |
CN1215432A (zh) * | 1996-04-05 | 1999-04-28 | 索尔克生物学研究所 | 调节外源性基因在哺乳动物系统中表达的激素介导的方法及其相关产物 |
FR2748753B1 (fr) * | 1996-05-20 | 1998-08-14 | Transgene Sa | Nouveaux vecteurs adenoviraux pour la therapie genique |
WO1998037185A2 (fr) * | 1997-02-20 | 1998-08-27 | The Board Of Regents Of The University Of Texas System | Vecteurs pour expression genique regulee |
-
1998
- 1998-08-28 FR FR9810842A patent/FR2782732A1/fr active Pending
-
1999
- 1999-08-27 AU AU54262/99A patent/AU5426299A/en not_active Abandoned
- 1999-08-27 CA CA002341775A patent/CA2341775A1/fr not_active Abandoned
- 1999-08-27 WO PCT/FR1999/002051 patent/WO2000012741A2/fr not_active Application Discontinuation
- 1999-08-27 EP EP99940240A patent/EP1108051A2/fr not_active Withdrawn
- 1999-08-27 JP JP2000567726A patent/JP2002523106A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
FR2782732A1 (fr) | 2000-03-03 |
AU5426299A (en) | 2000-03-21 |
CA2341775A1 (fr) | 2000-03-09 |
WO2000012741A3 (fr) | 2000-05-04 |
WO2000012741A9 (fr) | 2001-03-29 |
WO2000012741A2 (fr) | 2000-03-09 |
EP1108051A2 (fr) | 2001-06-20 |
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