JP2002522009A - Ste−20関連蛋白質キナーゼ - Google Patents

Ste−20関連蛋白質キナーゼ

Info

Publication number
JP2002522009A
JP2002522009A JP2000543584A JP2000543584A JP2002522009A JP 2002522009 A JP2002522009 A JP 2002522009A JP 2000543584 A JP2000543584 A JP 2000543584A JP 2000543584 A JP2000543584 A JP 2000543584A JP 2002522009 A JP2002522009 A JP 2002522009A
Authority
JP
Japan
Prior art keywords
seq
positions
kinase
sequence
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2000543584A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002522009A5 (https=
Inventor
グレゴリー プロウマン
リカルド マルティネーズ
デイビッド ホイット
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sugen LLC
Original Assignee
Sugen LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sugen LLC filed Critical Sugen LLC
Publication of JP2002522009A publication Critical patent/JP2002522009A/ja
Publication of JP2002522009A5 publication Critical patent/JP2002522009A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2000543584A 1998-04-14 1999-04-13 Ste−20関連蛋白質キナーゼ Withdrawn JP2002522009A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8178498P 1998-04-14 1998-04-14
US60/081,784 1998-04-14
PCT/US1999/008150 WO1999053036A2 (en) 1998-04-14 1999-04-13 Ste20-related protein kinases

Publications (2)

Publication Number Publication Date
JP2002522009A true JP2002522009A (ja) 2002-07-23
JP2002522009A5 JP2002522009A5 (https=) 2006-05-25

Family

ID=22166386

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000543584A Withdrawn JP2002522009A (ja) 1998-04-14 1999-04-13 Ste−20関連蛋白質キナーゼ

Country Status (10)

Country Link
US (5) US6680170B2 (https=)
EP (1) EP1073723B1 (https=)
JP (1) JP2002522009A (https=)
AT (1) ATE302269T1 (https=)
AU (1) AU3642499A (https=)
CA (1) CA2369172A1 (https=)
DE (1) DE69926742T2 (https=)
DK (1) DK1073723T3 (https=)
ES (1) ES2248997T3 (https=)
WO (1) WO1999053036A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006507835A (ja) 2002-11-27 2006-03-09 スージェン・インコーポレーテッド リン酸特異的pak抗体および診断キット
JP2012023006A (ja) * 2010-07-15 2012-02-02 Hyundai Motor Co Ltd リチウム二次電池用陽極材料及びその製造方法並びにその材料を含むリチウム二次電池

Families Citing this family (29)

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US7078182B1 (en) * 1998-04-14 2006-07-18 Board Of Regents, The University Of Texas System TAO protein kinase polypeptides and methods of use therefor
US6013500A (en) * 1998-05-21 2000-01-11 The Trustees Of Columbia University In The City Of New York PAK4, a novel gene encoding a serine/threonine kinase
JP2002525058A (ja) * 1998-09-10 2002-08-13 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー プロテインキナーゼkiaa0551の薬剤としての使用
CA2362936A1 (en) * 1999-02-19 2000-08-24 Mcmaster University A caspase activated protein kinase
WO2000060062A2 (en) * 1999-04-01 2000-10-12 Astrazeneca Uk Limited Human signal transduction serine/threonine protein kinase
US6558903B1 (en) * 1999-06-30 2003-05-06 Millennium Pharmaceuticals, Inc. Kinases and uses thereof
AU6181000A (en) * 1999-07-29 2001-02-19 Chugai Research Institute For Molecular Medicine, Inc. Novel genes encoding protein kinase/protein phosphatase
US20030104622A1 (en) * 1999-09-01 2003-06-05 Robbins Paul D. Identification of peptides that facilitate uptake and cytoplasmic and/or nuclear transport of proteins, DNA and viruses
US6861239B1 (en) 1999-09-20 2005-03-01 New York University Genes and polynucleotides associated with ultraviolet radiation-mediated skin damage and uses thereof
US7005285B1 (en) 1999-11-15 2006-02-28 Pharmacia & Italia S.P.A. Human p21-activated kinase 5 polypeptide
AU2001234544A1 (en) * 2000-01-25 2001-08-07 Sugen, Inc. Novel human protein kinases and protein kinase-like enzymes
AU2002223950A1 (en) * 2000-09-20 2002-04-02 Qlt Inc. Cancer associated protein kinases and their uses
AU2002243539A1 (en) * 2001-01-12 2002-07-24 Incyte Genomics, Inc. Molecules for disease detection and treatment
US7265214B2 (en) * 2001-10-19 2007-09-04 Rigel Pharmaceuticals, Inc. Germinal center kinase proteins, compositions and methods of use
US7482138B2 (en) 2001-12-28 2009-01-27 The Trustees Of Columbia University In The City Of New York PAK5-related compositions and methods
JP4522855B2 (ja) * 2002-07-05 2010-08-11 スージェン, インク. GEF−H1b:バイオマーカー,その複合体,アッセイおよび治療用途
GB0220770D0 (en) * 2002-09-06 2002-10-16 Ares Trading Sa Proteins
EP1597361A2 (en) * 2002-12-23 2005-11-23 Devgen NV Kinase sequences useful for developing compounds for the prevention and/or treatment of metabolic diseases and nucleotide sequences encoding such kinase sequences
GB2396615A (en) * 2002-12-23 2004-06-30 Devgen Nv Kinase sequences useful for developing compounds for the prevention and/or treatment of metabolic diseases
US20040242461A1 (en) * 2003-04-08 2004-12-02 Schneider Michael D. Modulators of telomere stability
US20060035242A1 (en) * 2004-08-13 2006-02-16 Michelitsch Melissa D Prion-specific peptide reagents
NZ580256A (en) * 2003-08-13 2011-07-29 Novartis Vaccines & Diagnostic Prion-specific peptide reagents comprising the sequence KKRPKPGG
AU2004275876B2 (en) * 2003-09-25 2011-03-31 Coley Pharmaceutical Gmbh Nucleic acid-lipophilic conjugates
WO2005111234A2 (en) * 2004-05-12 2005-11-24 Sugen, Inc. Methods of using zc1 and zc3 kinase substrate phosphorylation as biomarkers
US20090130774A1 (en) * 2005-01-13 2009-05-21 David Peretz Elisa assays using prion-specific peptide reagents
WO2006076497A2 (en) * 2005-01-13 2006-07-20 Novartis Vaccines And Diagnostics Inc. Osplation of pathogenic prions
WO2006076683A2 (en) * 2005-01-13 2006-07-20 Novartis Vaccines And Diagnostics Inc. Isolation and detection of pathogenic prions
EP1931695B1 (en) * 2005-09-09 2013-04-10 Novartis AG Prion-specific peptoid reagents
EP2282753A1 (en) * 2008-04-30 2011-02-16 Novartis AG Assay for pathogenic conformers

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Publication number Priority date Publication date Assignee Title
US4343940A (en) 1979-02-13 1982-08-10 Mead Johnson & Company Anti-tumor quinazoline compounds
DE3069468D1 (en) 1979-12-19 1984-11-22 Nat Res Dev Quinazoline derivatives, processes for their preparation, compositions containing them and their use as anti-cancer agents
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
DE3611194A1 (de) 1986-04-04 1987-10-08 Bayer Ag Cancerostatisches mittel
US5217999A (en) 1987-12-24 1993-06-08 Yissum Research Development Company Of The Hebrew University Of Jerusalem Styryl compounds which inhibit EGF receptor protein tyrosine kinase
DE3920029C2 (de) 1988-06-30 1999-05-20 Clariant Finance Bvi Ltd Farbstoffe zum Färben von Kunststoffen
WO1991015495A1 (en) 1990-04-02 1991-10-17 Pfizer Inc. Benzylphosphonic acid tyrosine kinase inhibitors
US5302606A (en) 1990-04-16 1994-04-12 Rhone-Poulenc Rorer Pharmaceuticals Inc. Styryl-substituted pyridyl compounds which inhibit EGF receptor tyrosine kinase
SG64322A1 (en) 1991-05-10 1999-04-27 Rhone Poulenc Rorer Int Bis mono and bicyclic aryl and heteroaryl compounds which inhibit egf and/or pdgf receptor tyrosine kinase
FI935279L (fi) 1991-05-29 1993-11-26 Pfizer Tricykliska polyhydroxyltyrosinkinasininhibitorer
NZ243082A (en) 1991-06-28 1995-02-24 Ici Plc 4-anilino-quinazoline derivatives; pharmaceutical compositions, preparatory processes, and use thereof
US5298422A (en) 1991-11-06 1994-03-29 Baylor College Of Medicine Myogenic vector systems
GB9300059D0 (en) 1992-01-20 1993-03-03 Zeneca Ltd Quinazoline derivatives
GB9205320D0 (en) 1992-03-11 1992-04-22 Ici Plc Anti-tumour compounds
WO1994003427A1 (en) 1992-08-06 1994-02-17 Warner-Lambert Company 2-thioindoles (selenoindoles) and related disulfides (selenides) which inhibit protein tyrosine kinases and which have antitumor properties
US5330992A (en) 1992-10-23 1994-07-19 Sterling Winthrop Inc. 1-cyclopropyl-4-pyridyl-quinolinones
US5366889A (en) * 1992-11-30 1994-11-22 The General Hospital Corporation DNA encoding a protein-coupled receptor kinase
GB9226855D0 (en) 1992-12-23 1993-02-17 Erba Carlo Spa Vinylene-azaindole derivatives and process for their preparation
GB9501567D0 (en) 1995-01-26 1995-03-15 Pharmacia Spa Hydrosoluble 3-arylidene-2-oxindole derivatives as tyrosine kinase inhibitors
AU3118297A (en) * 1996-05-07 1997-11-26 General Hospital Corporation, The Sok-1 and methods of use
WO1998015635A2 (en) 1996-10-04 1998-04-16 Connaught Laboratories Limited Treatment of cancer using a recombinant poxvirus containing a nucleic acid sequence encoding a cytokine
AU8296698A (en) * 1997-07-08 1999-02-08 Cadus Pharmaceutical Corporation (kds) protein kinase molecules and uses related thereto
WO1999007854A2 (en) * 1997-08-11 1999-02-18 Ontogeny, Inc. Serine/threonine kinase, and uses related thereto
GB9719920D0 (en) * 1997-09-19 1997-11-19 Zeneca Ltd Human Ste20-Like Stress Activated Serine/Threonine Kinase
GB9726851D0 (en) * 1997-12-19 1998-02-18 Zeneca Ltd Human signal transduction serine/threonine kinase
US6013500A (en) * 1998-05-21 2000-01-11 The Trustees Of Columbia University In The City Of New York PAK4, a novel gene encoding a serine/threonine kinase

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006507835A (ja) 2002-11-27 2006-03-09 スージェン・インコーポレーテッド リン酸特異的pak抗体および診断キット
JP2012023006A (ja) * 2010-07-15 2012-02-02 Hyundai Motor Co Ltd リチウム二次電池用陽極材料及びその製造方法並びにその材料を含むリチウム二次電池

Also Published As

Publication number Publication date
US6680170B2 (en) 2004-01-20
US20070072261A1 (en) 2007-03-29
US20030050230A1 (en) 2003-03-13
US20040224323A1 (en) 2004-11-11
AU3642499A (en) 1999-11-01
US6656716B1 (en) 2003-12-02
EP1073723A2 (en) 2001-02-07
ATE302269T1 (de) 2005-09-15
WO1999053036A9 (en) 2000-02-17
CA2369172A1 (en) 1999-10-21
EP1073723B1 (en) 2005-08-17
DE69926742D1 (de) 2005-09-22
WO1999053036A2 (en) 1999-10-21
ES2248997T3 (es) 2006-03-16
WO1999053036A3 (en) 2000-05-11
DE69926742T2 (de) 2006-06-14
DK1073723T3 (da) 2006-01-02
US20050142625A1 (en) 2005-06-30

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