JP2002519154A - 生体再吸収性ポリマーのブレンド - Google Patents
生体再吸収性ポリマーのブレンドInfo
- Publication number
- JP2002519154A JP2002519154A JP2000557872A JP2000557872A JP2002519154A JP 2002519154 A JP2002519154 A JP 2002519154A JP 2000557872 A JP2000557872 A JP 2000557872A JP 2000557872 A JP2000557872 A JP 2000557872A JP 2002519154 A JP2002519154 A JP 2002519154A
- Authority
- JP
- Japan
- Prior art keywords
- bioresorbable
- polymer
- composition according
- bioresorbable polymer
- block
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 229920002959 polymer blend Polymers 0.000 title description 4
- 239000000203 mixture Substances 0.000 claims abstract description 73
- 229920000642 polymer Polymers 0.000 claims abstract description 72
- 238000004519 manufacturing process Methods 0.000 claims abstract description 19
- 229920001577 copolymer Polymers 0.000 claims abstract description 10
- 239000004626 polylactic acid Substances 0.000 claims description 28
- 229920000747 poly(lactic acid) Polymers 0.000 claims description 26
- 229920001400 block copolymer Polymers 0.000 claims description 21
- 229920000954 Polyglycolide Polymers 0.000 claims description 15
- 238000000926 separation method Methods 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 9
- 239000000178 monomer Substances 0.000 claims description 8
- YFHICDDUDORKJB-UHFFFAOYSA-N trimethylene carbonate Chemical compound O=C1OCCCO1 YFHICDDUDORKJB-UHFFFAOYSA-N 0.000 claims description 7
- 125000004122 cyclic group Chemical group 0.000 claims description 6
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 claims description 6
- 239000004633 polyglycolic acid Substances 0.000 claims description 6
- PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical compound O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 claims description 5
- VPVXHAANQNHFSF-UHFFFAOYSA-N 1,4-dioxan-2-one Chemical compound O=C1COCCO1 VPVXHAANQNHFSF-UHFFFAOYSA-N 0.000 claims description 4
- 239000000155 melt Substances 0.000 claims description 4
- 229920000515 polycarbonate Polymers 0.000 claims description 4
- 239000004417 polycarbonate Substances 0.000 claims description 4
- 229920005604 random copolymer Polymers 0.000 claims description 4
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 claims description 3
- 241001465754 Metazoa Species 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- -1 polytrimethylene carbonate Polymers 0.000 claims description 3
- 229920003232 aliphatic polyester Polymers 0.000 claims description 2
- 150000001408 amides Chemical class 0.000 claims description 2
- 150000008064 anhydrides Chemical class 0.000 claims description 2
- 150000001720 carbohydrates Chemical class 0.000 claims description 2
- 230000002950 deficient Effects 0.000 claims description 2
- 150000002148 esters Chemical class 0.000 claims description 2
- 229920001519 homopolymer Polymers 0.000 claims description 2
- 150000002905 orthoesters Chemical class 0.000 claims description 2
- 229920000728 polyester Polymers 0.000 claims description 2
- 229920000166 polytrimethylene carbonate Polymers 0.000 claims description 2
- 229920006395 saturated elastomer Polymers 0.000 claims description 2
- 238000001356 surgical procedure Methods 0.000 claims description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 239000007943 implant Substances 0.000 abstract description 2
- 230000015556 catabolic process Effects 0.000 description 35
- 238000006731 degradation reaction Methods 0.000 description 35
- 239000000463 material Substances 0.000 description 20
- MFRCZYUUKMFJQJ-UHFFFAOYSA-N 1,4-dioxane-2,5-dione;1,3-dioxan-2-one Chemical compound O=C1OCCCO1.O=C1COC(=O)CO1 MFRCZYUUKMFJQJ-UHFFFAOYSA-N 0.000 description 17
- 229920002988 biodegradable polymer Polymers 0.000 description 12
- 239000004621 biodegradable polymer Substances 0.000 description 12
- 238000012360 testing method Methods 0.000 description 12
- 239000004632 polycaprolactone Substances 0.000 description 9
- 229920001610 polycaprolactone Polymers 0.000 description 9
- 210000001519 tissue Anatomy 0.000 description 7
- 238000004627 transmission electron microscopy Methods 0.000 description 7
- 208000034530 PLAA-associated neurodevelopmental disease Diseases 0.000 description 5
- 238000005191 phase separation Methods 0.000 description 5
- 230000008901 benefit Effects 0.000 description 4
- 239000012467 final product Substances 0.000 description 4
- 238000002347 injection Methods 0.000 description 4
- 239000007924 injection Substances 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 238000012937 correction Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000001727 in vivo Methods 0.000 description 3
- 239000011159 matrix material Substances 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 239000008363 phosphate buffer Substances 0.000 description 3
- 239000011148 porous material Substances 0.000 description 3
- 230000008439 repair process Effects 0.000 description 3
- 238000001878 scanning electron micrograph Methods 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- SJZRECIVHVDYJC-UHFFFAOYSA-M 4-hydroxybutyrate Chemical compound OCCCC([O-])=O SJZRECIVHVDYJC-UHFFFAOYSA-M 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 description 2
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000000354 decomposition reaction Methods 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 230000009477 glass transition Effects 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 229920002463 poly(p-dioxanone) polymer Polymers 0.000 description 2
- 239000000622 polydioxanone Substances 0.000 description 2
- 238000007142 ring opening reaction Methods 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- ORILYTVJVMAKLC-UHFFFAOYSA-N Adamantane Natural products C1C(C2)CC3CC1CC2C3 ORILYTVJVMAKLC-UHFFFAOYSA-N 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 230000002925 chemical effect Effects 0.000 description 1
- 239000007857 degradation product Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 229920006158 high molecular weight polymer Polymers 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 239000011256 inorganic filler Substances 0.000 description 1
- 229910003475 inorganic filler Inorganic materials 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- VUZPPFZMUPKLLV-UHFFFAOYSA-N methane;hydrate Chemical compound C.O VUZPPFZMUPKLLV-UHFFFAOYSA-N 0.000 description 1
- 229920006113 non-polar polymer Polymers 0.000 description 1
- 210000004197 pelvis Anatomy 0.000 description 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229920006112 polar polymer Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000009103 reabsorption Effects 0.000 description 1
- 239000013557 residual solvent Substances 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/06—At least partially resorbable materials
- A61L17/10—At least partially resorbable materials containing macromolecular materials
- A61L17/12—Homopolymers or copolymers of glycolic acid or lactic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/041—Mixtures of macromolecular compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
- C08L67/04—Polyesters derived from hydroxycarboxylic acids, e.g. lactones
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L69/00—Compositions of polycarbonates; Compositions of derivatives of polycarbonates
- C08L69/005—Polyester-carbonates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Polymers & Plastics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Materials For Medical Uses (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Medicinal Preparation (AREA)
- Graft Or Block Polymers (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9814609.5 | 1998-07-07 | ||
| GBGB9814609.5A GB9814609D0 (en) | 1998-07-07 | 1998-07-07 | Polymers |
| PCT/GB1999/002154 WO2000001426A1 (en) | 1998-07-07 | 1999-07-05 | Blend of bioresorbable polymers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002519154A true JP2002519154A (ja) | 2002-07-02 |
| JP2002519154A5 JP2002519154A5 (https=) | 2006-03-09 |
Family
ID=10835016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000557872A Ceased JP2002519154A (ja) | 1998-07-07 | 1999-07-05 | 生体再吸収性ポリマーのブレンド |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6583232B1 (https=) |
| EP (1) | EP1094850B1 (https=) |
| JP (1) | JP2002519154A (https=) |
| AT (1) | ATE265239T1 (https=) |
| AU (1) | AU740835B2 (https=) |
| CA (1) | CA2335637A1 (https=) |
| DE (1) | DE69916839T2 (https=) |
| GB (1) | GB9814609D0 (https=) |
| WO (1) | WO2000001426A1 (https=) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003531927A (ja) * | 2000-04-27 | 2003-10-28 | マクロメド・インコーポレーテッド | トリブロックポリエステルポリエチレングリコールコポリマーの混合物 |
| JP2009532087A (ja) * | 2006-03-31 | 2009-09-10 | アボット カーディオヴァスキュラー システムズ インコーポレイテッド | 連続相及び不連続相を有する分解性ポリマーの埋込み型医療デバイス |
| JP2010504817A (ja) * | 2006-09-29 | 2010-02-18 | アボット カーディオヴァスキュラー システムズ インコーポレイテッド | ポリマーブレンド−バイオセラミック複合体製の埋込型医用デバイス |
| JP2011530331A (ja) * | 2008-08-06 | 2011-12-22 | メドトロニック，インコーポレイテッド | 生物分解性ポリマーのブレンドを含む医療デバイスおよび方法 |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0116341D0 (en) | 2001-07-04 | 2001-08-29 | Smith & Nephew | Biodegradable polymer systems |
| US7070610B2 (en) | 2002-03-30 | 2006-07-04 | Samyang Corporation | Monofilament suture and manufacturing method thereof |
| US20070265582A1 (en) * | 2002-06-12 | 2007-11-15 | University Of Southern California | Injection Devices for Unimpeded Target Location Testing |
| AU2003236525A1 (en) * | 2002-06-12 | 2003-12-31 | Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California | Injection devices and methods for testing implants and for unimpeded target location testing |
| US7012106B2 (en) | 2003-03-28 | 2006-03-14 | Ethicon, Inc. | Reinforced implantable medical devices |
| US7172814B2 (en) * | 2003-06-03 | 2007-02-06 | Bio-Tec Biologische Naturverpackungen Gmbh & Co | Fibrous sheets coated or impregnated with biodegradable polymers or polymers blends |
| US8529625B2 (en) | 2003-08-22 | 2013-09-10 | Smith & Nephew, Inc. | Tissue repair and replacement |
| US8016865B2 (en) | 2003-09-29 | 2011-09-13 | Depuy Mitek, Inc. | Method of performing anterior cruciate ligament reconstruction using biodegradable interference screw |
| GB0329654D0 (en) | 2003-12-23 | 2004-01-28 | Smith & Nephew | Tunable segmented polyacetal |
| US20060120994A1 (en) * | 2004-10-29 | 2006-06-08 | Cotton Nicholas J | Bioabsorbable polymers |
| US8545866B2 (en) | 2004-10-29 | 2013-10-01 | Smith & Nephew, Inc. | Bioabsorbable polymers |
| US7150929B2 (en) * | 2004-12-29 | 2006-12-19 | Utc Fuel Cells, Llc | Fuel cell coolers with inverse flow and condensation zone |
| US8128670B2 (en) * | 2005-04-15 | 2012-03-06 | Biodynamics Llc | Surgical expansion fasteners |
| US7579413B2 (en) * | 2005-04-29 | 2009-08-25 | Board Of Trustees Of Michigan State University | Hyperbranched polymer modified biopolymers, their biobased materials and process for the preparation thereof |
| US7655584B2 (en) * | 2005-07-29 | 2010-02-02 | Gore Enterprise Holdings, Inc. | Highly porous self-cohered web materials |
| US20070026040A1 (en) * | 2005-07-29 | 2007-02-01 | Crawley Jerald M | Composite self-cohered web materials |
| US7850810B2 (en) * | 2005-07-29 | 2010-12-14 | Gore Enterprise Holdings, Inc. | Method of making porous self-cohered web materials |
| US20070027551A1 (en) * | 2005-07-29 | 2007-02-01 | Farnsworth Ted R | Composite self-cohered web materials |
| US7604668B2 (en) * | 2005-07-29 | 2009-10-20 | Gore Enterprise Holdings, Inc. | Composite self-cohered web materials |
| US7655288B2 (en) * | 2005-07-29 | 2010-02-02 | Gore Enterprise Holdings, Inc. | Composite self-cohered web materials |
| US8048503B2 (en) * | 2005-07-29 | 2011-11-01 | Gore Enterprise Holdings, Inc. | Highly porous self-cohered web materials |
| US20070026039A1 (en) * | 2005-07-29 | 2007-02-01 | Drumheller Paul D | Composite self-cohered web materials |
| US20070036842A1 (en) * | 2005-08-15 | 2007-02-15 | Concordia Manufacturing Llc | Non-woven scaffold for tissue engineering |
| JP2009504929A (ja) * | 2005-08-18 | 2009-02-05 | スミス アンド ネフュー ピーエルシー | 高強度デバイス及び複合材料 |
| US7833253B2 (en) | 2006-01-17 | 2010-11-16 | Biodynamics Llc | Craniotomy closures and plugs |
| CA2637606C (en) | 2006-01-19 | 2013-03-19 | Osteotech, Inc. | Porous osteoimplant |
| US9163141B2 (en) * | 2006-04-27 | 2015-10-20 | Cryovac, Inc. | Polymeric blend comprising polylactic acid |
| US8206796B2 (en) | 2006-04-27 | 2012-06-26 | Cryovac, Inc. | Multilayer film comprising polylactic acid |
| US20080033540A1 (en) * | 2006-08-01 | 2008-02-07 | Yunbing Wang | Methods to prepare polymer blend implantable medical devices |
| EP2142353A1 (en) | 2007-04-18 | 2010-01-13 | Smith & Nephew PLC | Expansion moulding of shape memory polymers |
| WO2008130954A2 (en) | 2007-04-19 | 2008-10-30 | Smith & Nephew, Inc. | Graft fixation |
| JP5520814B2 (ja) * | 2007-04-19 | 2014-06-11 | スミス アンド ネフュー インコーポレーテッド | マルチモーダル形状記憶ポリマー |
| US8802126B2 (en) | 2008-06-30 | 2014-08-12 | Abbott Cardiovascular Systems Inc. | Polyester implantable medical device with controlled in vivo biodegradability |
| US9399086B2 (en) * | 2009-07-24 | 2016-07-26 | Warsaw Orthopedic, Inc | Implantable medical devices |
| US9173978B2 (en) | 2010-09-22 | 2015-11-03 | Ethicon, Inc. | Bioabsorbable polymeric compositions, processing methods, and medical devices therefrom |
| SG194441A1 (en) | 2011-04-15 | 2013-12-30 | Polyone Corp | Flame retardant polylactic acid compounds |
| WO2012151432A1 (en) | 2011-05-03 | 2012-11-08 | Biodynamics, Llc | Craniotomy plugs |
| US9309403B2 (en) | 2012-10-17 | 2016-04-12 | Polyone Corporation | Heat resistant, flame retardant polylactic acid compounds |
| WO2014062573A1 (en) | 2012-10-17 | 2014-04-24 | Polyone Corporation | Flame retardant polylactic acid compounds |
| US20140172013A1 (en) * | 2012-12-14 | 2014-06-19 | Ecd Medical | Vascular Closure Devices |
| US20170225395A1 (en) * | 2014-08-05 | 2017-08-10 | University Of Washington | Three-dimensional printed mechanoresponsive materials and related methods |
| CA3104950A1 (en) | 2018-06-29 | 2020-01-02 | Evonik Operations Gmbh | Biodegradable polymer blends for manufacturing medical devices |
| WO2025099063A1 (en) | 2023-11-06 | 2025-05-15 | Evonik Operations Gmbh | Multilayer nerve regeneration guidance tube |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04226527A (ja) * | 1990-07-06 | 1992-08-17 | American Cyanamid Co | 生吸収性セグメント化コポリマー |
| JPH08504850A (ja) * | 1992-11-06 | 1996-05-28 | リュークスニベルシテイト テ グロニンゲン | ゴム変性されたポリラクチドおよび／またはグリコリド組成物 |
| JPH08198957A (ja) * | 1995-01-26 | 1996-08-06 | Takasago Internatl Corp | 生分解性高分子用可塑剤 |
| JPH10204720A (ja) * | 1997-01-14 | 1998-08-04 | Gunze Ltd | 生分解性フラットヤーン |
| JP2001518364A (ja) * | 1997-10-02 | 2001-10-16 | ゴア エンタープライズ ホールディングス，インコーポレイティド | 自己凝集性の連続フィラメントの不織ウェブ |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4243775A (en) * | 1978-11-13 | 1981-01-06 | American Cyanamid Company | Synthetic polyester surgical articles |
| US4429080A (en) * | 1982-07-01 | 1984-01-31 | American Cyanamid Company | Synthetic copolymer surgical articles and method of manufacturing the same |
| US4844854A (en) * | 1987-09-22 | 1989-07-04 | United States Surgical Corporation | Process for making a surgical device using two-phase compositions |
| US5120802A (en) * | 1987-12-17 | 1992-06-09 | Allied-Signal Inc. | Polycarbonate-based block copolymers and devices |
| EP0390860B1 (en) * | 1987-12-17 | 1995-04-12 | United States Surgical Corporation | Medical devices fabricated from homopolymers and copolymers having recurring carbonate units |
| US5252642A (en) * | 1989-03-01 | 1993-10-12 | Biopak Technology, Ltd. | Degradable impact modified polyactic acid |
| US5080665A (en) * | 1990-07-06 | 1992-01-14 | American Cyanamid Company | Deformable, absorbable surgical device |
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- 1999-07-05 US US09/719,857 patent/US6583232B1/en not_active Expired - Fee Related
- 1999-07-05 WO PCT/GB1999/002154 patent/WO2000001426A1/en not_active Ceased
- 1999-07-05 DE DE69916839T patent/DE69916839T2/de not_active Expired - Fee Related
- 1999-07-05 JP JP2000557872A patent/JP2002519154A/ja not_active Ceased
- 1999-07-05 EP EP99929576A patent/EP1094850B1/en not_active Expired - Lifetime
- 1999-07-05 CA CA002335637A patent/CA2335637A1/en not_active Abandoned
- 1999-07-05 AT AT99929576T patent/ATE265239T1/de not_active IP Right Cessation
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| JPH04226527A (ja) * | 1990-07-06 | 1992-08-17 | American Cyanamid Co | 生吸収性セグメント化コポリマー |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003531927A (ja) * | 2000-04-27 | 2003-10-28 | マクロメド・インコーポレーテッド | トリブロックポリエステルポリエチレングリコールコポリマーの混合物 |
| JP4895457B2 (ja) * | 2000-04-27 | 2012-03-14 | プロセリックス・ソルト・レイク・シティ，インコーポレーテッド | トリブロックポリエステルポリエチレングリコールコポリマーの混合物 |
| JP2009532087A (ja) * | 2006-03-31 | 2009-09-10 | アボット カーディオヴァスキュラー システムズ インコーポレイテッド | 連続相及び不連続相を有する分解性ポリマーの埋込み型医療デバイス |
| JP2010504817A (ja) * | 2006-09-29 | 2010-02-18 | アボット カーディオヴァスキュラー システムズ インコーポレイテッド | ポリマーブレンド−バイオセラミック複合体製の埋込型医用デバイス |
| JP2011530331A (ja) * | 2008-08-06 | 2011-12-22 | メドトロニック，インコーポレイテッド | 生物分解性ポリマーのブレンドを含む医療デバイスおよび方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| DE69916839D1 (de) | 2004-06-03 |
| US6583232B1 (en) | 2003-06-24 |
| AU740835B2 (en) | 2001-11-15 |
| EP1094850B1 (en) | 2004-04-28 |
| GB9814609D0 (en) | 1998-09-02 |
| EP1094850A1 (en) | 2001-05-02 |
| CA2335637A1 (en) | 2000-01-13 |
| WO2000001426A1 (en) | 2000-01-13 |
| ATE265239T1 (de) | 2004-05-15 |
| AU4636299A (en) | 2000-01-24 |
| DE69916839T2 (de) | 2005-04-14 |
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