JPH08504850A - ゴム変性されたポリラクチドおよび/またはグリコリド組成物 - Google Patents
ゴム変性されたポリラクチドおよび/またはグリコリド組成物Info
- Publication number
- JPH08504850A JPH08504850A JP6511944A JP51194494A JPH08504850A JP H08504850 A JPH08504850 A JP H08504850A JP 6511944 A JP6511944 A JP 6511944A JP 51194494 A JP51194494 A JP 51194494A JP H08504850 A JPH08504850 A JP H08504850A
- Authority
- JP
- Japan
- Prior art keywords
- rubber
- lactide
- matrix
- composition according
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
- C08L67/04—Polyesters derived from hydroxycarboxylic acids, e.g. lactones
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
- C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
- C08G63/08—Lactones or lactides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/64—Polyesters containing both carboxylic ester groups and carbonate groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polyesters Or Polycarbonates (AREA)
- Biological Depolymerization Polymers (AREA)
- Materials For Medical Uses (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.マトリックスおよび別個のゴム相から成り、該マトリックスはラクチドお よび/またはグリコリド(共)重合体を基材としており、そして別個の相として 存在する分解性のゴム相を組成物基準で少なくとも5重量%含んで成り、高々1 0℃のガラス転移温度を有し、さらに破断時の延びが少なくとも120%である ことを特徴とするゴム変性された組成物。 2.ゴムがトリメチレンカーボネートを基材とする請求項1記載の組成物。 3.ゴムがε−カプロラクトンを基材とする請求項1または2記載の組成物。 4.ゴムがポリ(トリメチレン)カーボネート、L−ラクチドとε−カプロラ クトンの共重合体、グリコリドとε−カプロラクトンの共重合体、トリメチレン カーボネートとε−カプロラクトンの共重合体、δ−バレロラクトンとε−カプ ロラクトンの共重合体ならびにポリオールおよび前記の成分の一つまたはそれ以 上を基材とするゴムから成る群より選ばれる請求項1〜3記載の組成物。 5.ラクチドマトリックスが星型またはブロックゴムの存在下の重合により得 られる請求項1〜4記載の組成物。 6.ポリラクチドマトリックスおよび生物分解性ゴムが、互いに混和されてい る請求項1〜4記載の組成物。 7.ポリラクチドマトリックスが、ポリ(L−ラクチド)から成る請求項1〜 6記載の組成物。 8.ポリラクチドマトリックスが実質的に無定形であり、少なくとも15%の D−ラクチドを有するL−およびD−ラクチドの共重合体から成る請求項1〜6 記載の組成物。 9.ポリラクチドマトリックスが実質的に無定形で結晶化可能であり、そして 15%以下のD−ラクチドを有するD−ラクチドとL−ラクチドの共重合体を基 材とする請求項1〜6記載の組成物。 10.請求項1〜9記載の組成物の医療分野での用途。 11.請求項1〜9記載の組成物で全部または一部を製造された製品。 12.少なくとも一つの活性水素を有する化合物の存在下で、一つまたはそれ以 上のゴム形成モノマを重合し機能性ゴムを形成し、次いでマトリックスポリマを 機能性ゴムに添加し、そしてこれを該ゴムの存在下で重合することから成る請求 項1〜9記載の組成物を製造する方法。 13.ポリオールが少なくとも一つの活性水素を 有する化合物として用いられる請求項12記載の方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL9201949 | 1992-11-06 | ||
NL9201949A NL9201949A (nl) | 1992-11-06 | 1992-11-06 | Met rubber gemodificeerde polylactide-samenstelling. |
PCT/NL1993/000235 WO1994011441A1 (en) | 1992-11-06 | 1993-11-08 | Rubber-modified polylactide and/or glycolide composition |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH08504850A true JPH08504850A (ja) | 1996-05-28 |
JP3328285B2 JP3328285B2 (ja) | 2002-09-24 |
Family
ID=19861492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP51194494A Expired - Fee Related JP3328285B2 (ja) | 1992-11-06 | 1993-11-08 | ゴム変性されたポリラクチドおよび/またはグリコリド組成物 |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0667885B1 (ja) |
JP (1) | JP3328285B2 (ja) |
AU (1) | AU5577894A (ja) |
DE (1) | DE69312312T2 (ja) |
NL (1) | NL9201949A (ja) |
WO (1) | WO1994011441A1 (ja) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002519154A (ja) * | 1998-07-07 | 2002-07-02 | スミス アンド ネフュー ピーエルシー | 生体再吸収性ポリマーのブレンド |
JP2007046050A (ja) * | 2005-07-15 | 2007-02-22 | National Institute Of Advanced Industrial & Technology | 医療用樹脂組成物とその製造方法および成形体 |
KR100730432B1 (ko) * | 2001-05-17 | 2007-06-19 | 이니온 오위 | 재흡수가능한 고분자 조성물 |
WO2009041335A1 (ja) * | 2007-09-27 | 2009-04-02 | Toray Industries, Inc. | ポリマーアロイとその製造方法 |
JP2009532087A (ja) * | 2006-03-31 | 2009-09-10 | アボット カーディオヴァスキュラー システムズ インコーポレイテッド | 連続相及び不連続相を有する分解性ポリマーの埋込み型医療デバイス |
JP2010504817A (ja) * | 2006-09-29 | 2010-02-18 | アボット カーディオヴァスキュラー システムズ インコーポレイテッド | ポリマーブレンド−バイオセラミック複合体製の埋込型医用デバイス |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5641501A (en) * | 1994-10-11 | 1997-06-24 | Ethicon, Inc. | Absorbable polymer blends |
US5714573A (en) | 1995-01-19 | 1998-02-03 | Cargill, Incorporated | Impact modified melt-stable lactide polymer compositions and processes for manufacture thereof |
CN1136922C (zh) * | 1995-05-01 | 2004-02-04 | 株式会社三养社 | 可植入的可生物再吸收的膜及其制备方法 |
US5633342A (en) * | 1995-10-27 | 1997-05-27 | Chronopol, Inc. | Method for the synthesis of environmentally degradable block copolymers |
IT1282585B1 (it) * | 1996-02-08 | 1998-03-31 | Europ | Copolimeri a blocchi poliesterepolicarbonato contenenti segmenti di poli(caprolattone)e loro uso per la preparazione di matrici |
US5756651A (en) * | 1996-07-17 | 1998-05-26 | Chronopol, Inc. | Impact modified polylactide |
DE19641335A1 (de) * | 1996-10-08 | 1998-04-09 | Inst Textil & Faserforschung | Triblockterpolymer, seine Verwendung für chirurgisches Nahtmaterial und Verfahren zur Herstellung |
DE19641334A1 (de) * | 1996-10-08 | 1998-04-09 | Inst Textil & Faserforschung | Triblockterpolymer, seine Verwendung für medizinische Produkte und Verfahren zur Herstellung |
US5854383A (en) * | 1997-10-06 | 1998-12-29 | Ethicon, Inc. | Aliphatic polyesters of trimethylene carbonate epsilon-caprolactone and glycolide |
DE69913074T2 (de) * | 1998-10-01 | 2004-08-26 | Toyota Jidosha Kabushiki Kaisha, Toyota | Biodegradierbare Polyester/Polyestercarbonat-Mischung |
US6342065B1 (en) | 1999-03-17 | 2002-01-29 | Poly-Med, Inc. | High strength fibers of L-lactide copolymers ε-caprolactone and trimethylene carbonate and absorbable medical constructs thereof |
US6710135B2 (en) * | 2000-08-02 | 2004-03-23 | Mitsui Chemicals, Inc. | Resin composition and use thereof |
DE10041684A1 (de) | 2000-08-24 | 2002-03-07 | Inst Textil & Faserforschung | Beschichtungsmaterial zur medizinischen Behandlung aus resorbierbarem synthetischem Material, Verfahren zu seiner Herstellung und Verwendung in der Medizin |
EP1236753A1 (en) | 2001-03-02 | 2002-09-04 | Hycail B.V. | Environmentally degradable polymeric compounds, their preparation and use as hot melt adhesive |
KR100354828B1 (ko) | 2001-03-12 | 2002-10-05 | 주식회사 씨엠리서치 | 생분해성 폴리에스테르의 제조방법 및 그에 의해 제조된생분해성 폴리에스테르 |
EA005626B1 (ru) | 2001-03-23 | 2005-04-28 | Гумлинк А/С | Покрытая оболочкой разлагающаяся жевательная резинка с улучшенным сроком хранения и способ ее получения |
WO2002076228A1 (en) * | 2001-03-23 | 2002-10-03 | Gumlink A/S | Degradable resin substitute for chewing gum |
EP1370154B1 (en) * | 2001-03-23 | 2008-01-09 | Gumlink A/S | Degradable elastomers for chewing gum base |
US7122037B2 (en) * | 2001-05-17 | 2006-10-17 | Inion Ltd. | Bone fracture fastener and material for production thereof |
CA2501059C (en) * | 2002-09-24 | 2011-03-01 | Gumlink A/S | Degradable chewing gum polymer |
MXPA05002961A (es) | 2002-09-24 | 2005-06-03 | Gumlink As | Goma de mascar que comprende al menos dos diferentes polimeros biodegradables. |
US8591967B2 (en) | 2002-09-24 | 2013-11-26 | Gumlink A/S | Biodegradable chewing gum comprising at least one high molecular weight biodegradable polymer |
EP3047860A1 (en) | 2006-07-20 | 2016-07-27 | OrbusNeich Medical, Inc. | Bioabsorbable polymeric composition for a medical device |
US8691321B2 (en) | 2006-10-20 | 2014-04-08 | Orbusneich Medical, Inc. | Bioabsorbable polymeric composition and medical device background |
CN103249770A (zh) * | 2010-10-13 | 2013-08-14 | 道达尔研究技术弗吕公司 | 聚碳酸酯作为用于聚丙交酯的成核剂 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990001521A1 (en) * | 1988-08-08 | 1990-02-22 | Battelle Memorial Institute | Degradable thermoplastic from lactides |
DE3937272A1 (de) * | 1989-11-09 | 1991-05-16 | Boehringer Ingelheim Kg | Neue copolymere aus trimethylencarbonat und optisch inaktiven laktiden |
US5227415A (en) * | 1990-04-06 | 1993-07-13 | Director-General Of Agency Of Industrial Science And Technology | Biodegradable plastic composition |
US5080665A (en) * | 1990-07-06 | 1992-01-14 | American Cyanamid Company | Deformable, absorbable surgical device |
JPH04173746A (ja) * | 1990-11-07 | 1992-06-22 | Unitika Ltd | 徐放性機能を有する薬剤・ポリマー複合体 |
-
1992
- 1992-11-06 NL NL9201949A patent/NL9201949A/nl not_active Application Discontinuation
-
1993
- 1993-11-08 WO PCT/NL1993/000235 patent/WO1994011441A1/en active IP Right Grant
- 1993-11-08 JP JP51194494A patent/JP3328285B2/ja not_active Expired - Fee Related
- 1993-11-08 AU AU55778/94A patent/AU5577894A/en not_active Abandoned
- 1993-11-08 EP EP94901070A patent/EP0667885B1/en not_active Expired - Lifetime
- 1993-11-08 DE DE69312312T patent/DE69312312T2/de not_active Expired - Lifetime
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002519154A (ja) * | 1998-07-07 | 2002-07-02 | スミス アンド ネフュー ピーエルシー | 生体再吸収性ポリマーのブレンド |
KR100730432B1 (ko) * | 2001-05-17 | 2007-06-19 | 이니온 오위 | 재흡수가능한 고분자 조성물 |
JP2007046050A (ja) * | 2005-07-15 | 2007-02-22 | National Institute Of Advanced Industrial & Technology | 医療用樹脂組成物とその製造方法および成形体 |
JP2009532087A (ja) * | 2006-03-31 | 2009-09-10 | アボット カーディオヴァスキュラー システムズ インコーポレイテッド | 連続相及び不連続相を有する分解性ポリマーの埋込み型医療デバイス |
JP2010504817A (ja) * | 2006-09-29 | 2010-02-18 | アボット カーディオヴァスキュラー システムズ インコーポレイテッド | ポリマーブレンド−バイオセラミック複合体製の埋込型医用デバイス |
WO2009041335A1 (ja) * | 2007-09-27 | 2009-04-02 | Toray Industries, Inc. | ポリマーアロイとその製造方法 |
EP2194100A1 (en) * | 2007-09-27 | 2010-06-09 | Toray Industries, Inc. | Polymer alloy and process for producing the same |
US8338547B2 (en) | 2007-09-27 | 2012-12-25 | Toray Industries, Inc. | Polymer alloy and production method thereof |
Also Published As
Publication number | Publication date |
---|---|
DE69312312T2 (de) | 1998-01-08 |
JP3328285B2 (ja) | 2002-09-24 |
DE69312312D1 (de) | 1997-08-21 |
EP0667885A1 (en) | 1995-08-23 |
AU5577894A (en) | 1994-06-08 |
EP0667885B1 (en) | 1997-07-16 |
NL9201949A (nl) | 1994-06-01 |
WO1994011441A1 (en) | 1994-05-26 |
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