JP2002518011A5 - - Google Patents

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Publication number
JP2002518011A5
JP2002518011A5 JP2000554853A JP2000554853A JP2002518011A5 JP 2002518011 A5 JP2002518011 A5 JP 2002518011A5 JP 2000554853 A JP2000554853 A JP 2000554853A JP 2000554853 A JP2000554853 A JP 2000554853A JP 2002518011 A5 JP2002518011 A5 JP 2002518011A5
Authority
JP
Japan
Prior art keywords
bpi
analog
host cell
deleted
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000554853A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002518011A (ja
Filing date
Publication date
Priority claimed from US09/099,725 external-priority patent/US6013631A/en
Application filed filed Critical
Publication of JP2002518011A publication Critical patent/JP2002518011A/ja
Publication of JP2002518011A5 publication Critical patent/JP2002518011A5/ja
Pending legal-status Critical Current

Links

JP2000554853A 1998-06-19 1999-06-18 殺菌性／透過性増加タンパク質（ｂｐｉ）欠失アナログ Pending JP2002518011A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/099,725 US6013631A (en) 1998-06-19 1998-06-19 Bactericidal/permeability-increasing protein (BPI) deletion analogs
US09/099,725 1998-06-19
PCT/US1999/013860 WO1999066044A1 (en) 1998-06-19 1999-06-18 Bactericidal/permeability-increasing protein (bpi) deletion analogs

Publications (2)

Publication Number Publication Date
JP2002518011A JP2002518011A (ja) 2002-06-25
JP2002518011A5 true JP2002518011A5 (enExample) 2006-06-29

Family

ID=22276330

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000554853A Pending JP2002518011A (ja) 1998-06-19 1999-06-18 殺菌性／透過性増加タンパク質（ｂｐｉ）欠失アナログ

Country Status (9)

Country Link
US (4) US6013631A (enExample)
EP (1) EP1086230A1 (enExample)
JP (1) JP2002518011A (enExample)
CN (1) CN1273598C (enExample)
AU (1) AU755624B2 (enExample)
CA (1) CA2331880A1 (enExample)
MX (1) MXPA00011398A (enExample)
NZ (1) NZ508816A (enExample)
WO (1) WO1999066044A1 (enExample)

Families Citing this family (15)

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US5198541A (en) * 1987-08-11 1993-03-30 New York University Dna encoding bactericidal/permeability-increasing proteins
US6013631A (en) * 1998-06-19 2000-01-11 Xoma Corporation Bactericidal/permeability-increasing protein (BPI) deletion analogs
CA2373262A1 (en) * 1999-05-24 2000-11-30 Xoma (Us) Llc Therapeutic uses of bpi protein products in humans with otitis media with effusion
AU2002241589B2 (en) * 2000-12-01 2007-07-19 Xoma Technology Ltd. Modulation of pericyte proliferation using BPI protein products or BPI inhibitors
JP4554370B2 (ja) 2002-03-29 2010-09-29 ゾーマ テクノロジー リミテッド 多重遺伝子プラスミドおよび組み換えポリペプチドの発現増加法
JP4607010B2 (ja) * 2003-02-28 2011-01-05 中外製薬株式会社 タンパク質含有安定化製剤
JP2008541746A (ja) * 2005-06-03 2008-11-27 ビオヴィトルム・アクチボラゲット（プブリクト） 新規プロセス
EP1741440A1 (en) 2005-07-08 2007-01-10 Mellitus S.L. Use of BPI protein for the treatment of disorders of the metabolism and cardiovascular disorders
US8338376B2 (en) * 2006-10-20 2012-12-25 Biogen Idec Ma Inc. Compositions comprising variant LT-B-R-IG fusion proteins
WO2008112325A2 (en) * 2007-03-15 2008-09-18 Biogen Idec Ma Inc. Treatment of autoimmune disorders
CN108042807B (zh) 2011-04-05 2020-10-16 达纳-法伯癌症研究所有限公司 作为辐射缓和剂和辐射防护剂的bpi和其同源物的用途
GB201319620D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Immunosuppressive agents and their use in therapy
GB201319621D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Antimicrobial agents and their use in therapy
KR102270048B1 (ko) * 2020-07-10 2021-06-28 주식회사 녹십자 바리셀라 조스터 바이러스 표면 단백질 항원의 생산 방법
CN115947868A (zh) * 2022-09-28 2023-04-11 安君(北京)基因科技有限责任公司 Cxcl-bpi融合蛋白及其用途

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US5576292A (en) * 1987-08-11 1996-11-19 New York University Biologically active bactericidal/permeability-increasing protein fragments
US5198541A (en) * 1987-08-11 1993-03-30 New York University Dna encoding bactericidal/permeability-increasing proteins
US5334584A (en) * 1989-02-14 1994-08-02 Incyte Pharamaceuticals, Inc. Recombinant, non-glycosylated bpi protein and uses thereof
US5089274A (en) * 1989-02-14 1992-02-18 Incyte Pharmaceuticals, Inc. Use of bactericidal/permeability increasing protein or biologically active analogs thereof to treat endotoxin-related disorders
US5171739A (en) * 1989-02-14 1992-12-15 Incyte Pharmaceuticals, Inc. Treatment of endotoxin-associated shock and preventation thereof using a BPI protein
US5308834A (en) * 1989-02-14 1994-05-03 Incyte Pharmaceuticals, Inc. Treatment of endotoxin-associated shock and prevention thereof using a BPI protein
US5234912A (en) * 1989-02-14 1993-08-10 Incyte Pharmaceuticals, Inc. Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof
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WO1995002414A1 (en) * 1993-07-14 1995-01-26 Xoma Corporation Method for potentiating bpi protein product bactericidal activity by administration of lbp protein products
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US5643875A (en) * 1994-01-24 1997-07-01 Friedmann; Nadav Human therapeutic uses of bactericidal/permeability increasing (BPI) protein products
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US5447913A (en) * 1994-03-11 1995-09-05 Xoma Corporation Therapeutic uses of bactericidal/permeability-increasing protein dimer products
US5786324A (en) * 1994-03-24 1998-07-28 Regents Of The University Of Minnesota Synthetic peptides with bactericidal activity and endotoxin neutralizing activity for gram negative bacteria and methods for their use
US5578568A (en) * 1994-04-22 1996-11-26 Xoma Corporation Method of treating conditions associated with intestinal ischemia/reperfusion
US5532216A (en) * 1994-06-24 1996-07-02 Incyte Pharmaceuticals, Inc. Neutralization of non-lipopolysaccharide compounds by bactericidal/permeability-increasing protein
US5646114A (en) * 1994-07-11 1997-07-08 Xoma Corporation Anti-protozoan methods
JPH10508576A (ja) * 1994-09-15 1998-08-25 ゾーマ コーポレイション 抗真菌性ペプチド
US5912228A (en) * 1995-01-13 1999-06-15 Xoma Corporation Therapeutic compositions comprising bactericidal/permeability-increasing (BPI) protein products
US5494896A (en) * 1995-03-31 1996-02-27 Xoma Corporation Method of treating conditions associated with burn injuries
EP0839156A1 (en) * 1995-07-20 1998-05-06 Xoma Corporation Anti-fungal peptides
US5686414A (en) * 1995-11-14 1997-11-11 Xoma Corporation Methods of treating conditions associated with corneal transplantation
CA2235626C (en) * 1995-11-14 2002-01-01 Xoma Corporation Bactericidal permeability increasing protein (bpi) for treating conditions associated with corneal injury
EP0914144B1 (en) * 1996-05-10 2000-12-13 XOMA Technology Ltd. Therapeutic uses of bpi protein products for human meningococcemia
US5741779A (en) * 1996-05-10 1998-04-21 Xoma Corporation Antithrombotic materials and methods
US5945399A (en) * 1996-05-23 1999-08-31 Xoma Corporation Therapeutic uses of BPI protein products in humans with hemorrhage due to trauma
US5888973A (en) * 1996-08-09 1999-03-30 Xoma Corporation Anti-chlamydial uses of BPI protein products
EP0938331B1 (en) * 1996-11-01 2002-12-18 XOMA Technology Ltd. Therapeutic uses of bpi protein products in cystic fibrosis patients
US6013631A (en) * 1998-06-19 2000-01-11 Xoma Corporation Bactericidal/permeability-increasing protein (BPI) deletion analogs

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