ATE165976T1 - Behandlung von mycobakteriellen erkrankungen durch verabreichung von bakrerientötende, durchlässigkeitserhöhende proteinfragmente - Google Patents
Behandlung von mycobakteriellen erkrankungen durch verabreichung von bakrerientötende, durchlässigkeitserhöhende proteinfragmenteInfo
- Publication number
- ATE165976T1 ATE165976T1 AT94910876T AT94910876T ATE165976T1 AT E165976 T1 ATE165976 T1 AT E165976T1 AT 94910876 T AT94910876 T AT 94910876T AT 94910876 T AT94910876 T AT 94910876T AT E165976 T1 ATE165976 T1 AT E165976T1
- Authority
- AT
- Austria
- Prior art keywords
- permeability
- bacreriacidal
- administration
- treatment
- protein fragments
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 239000012634 fragment Substances 0.000 title 1
- 208000027531 mycobacterial infectious disease Diseases 0.000 title 1
- 241000186362 Mycobacterium leprae Species 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000035699 permeability Effects 0.000 abstract 1
- 201000008827 tuberculosis Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A61K38/1751—Bactericidal/permeability-increasing protein [BPI]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Marine Sciences & Fisheries (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3114593A | 1993-03-12 | 1993-03-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE165976T1 true ATE165976T1 (de) | 1998-05-15 |
Family
ID=21857874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94910876T ATE165976T1 (de) | 1993-03-12 | 1994-03-11 | Behandlung von mycobakteriellen erkrankungen durch verabreichung von bakrerientötende, durchlässigkeitserhöhende proteinfragmente |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0690721B1 (de) |
| AT (1) | ATE165976T1 (de) |
| AU (1) | AU6361894A (de) |
| CA (1) | CA2157925C (de) |
| DE (1) | DE69410254T2 (de) |
| DK (1) | DK0690721T3 (de) |
| ES (1) | ES2119185T3 (de) |
| GR (1) | GR3027620T3 (de) |
| WO (1) | WO1994020129A1 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5420019A (en) | 1993-02-02 | 1995-05-30 | Xoma Corporation | Stable bactericidal/permeability-increasing protein muteins |
| US5858974A (en) * | 1995-07-20 | 1999-01-12 | Xoma Corporation | Anti-fungal peptides |
| US5652332A (en) * | 1993-03-12 | 1997-07-29 | Xoma | Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof |
| US6214789B1 (en) | 1993-03-12 | 2001-04-10 | Xoma Corporation | Treatment of mycobacterial diseases by administration of bactericidal/permeability-increasing protein products |
| WO1995000641A1 (en) | 1993-06-17 | 1995-01-05 | Xoma Corporation | Lipopolysaccharide binding protein derivatives |
| US5770561A (en) * | 1993-07-14 | 1998-06-23 | Xoma Corporation | Method for potentiating BPI protein product bactericidal activity by administration of LBP protein products |
| WO1995002414A1 (en) * | 1993-07-14 | 1995-01-26 | Xoma Corporation | Method for potentiating bpi protein product bactericidal activity by administration of lbp protein products |
| US6759203B1 (en) | 1993-09-22 | 2004-07-06 | Xoma Corporation | Method for quantifying BPI in body fluids |
| CN1133634A (zh) * | 1993-09-22 | 1996-10-16 | 爱克斯欧玛公司 | 定量体液中的bpi的方法 |
| DE69430823T2 (de) * | 1993-09-22 | 2003-02-20 | Xoma Technology Ltd., Berkeley | Verfahren zur behandlung von gram-negativen bakterien infektion durch verabreichung von bakterientötendem/durchlässigkeiterhöhendem (bpi) proteinprodukt und antibiotikum |
| PT754050E (pt) * | 1994-01-14 | 2002-11-29 | Xoma Technology Ltd | Metodos e materiais contra bacterias gram-positivas |
| DE69526216T2 (de) * | 1994-01-14 | 2002-11-14 | Xoma Technology Ltd., Berkeley | Antifungaleverfahren und mitteln |
| US5447913A (en) | 1994-03-11 | 1995-09-05 | Xoma Corporation | Therapeutic uses of bactericidal/permeability-increasing protein dimer products |
| US6271203B1 (en) | 1994-07-07 | 2001-08-07 | Xoma Corporation | Anti-protozoan methods and materials |
| US5646114A (en) * | 1994-07-11 | 1997-07-08 | Xoma Corporation | Anti-protozoan methods |
| US5494896A (en) * | 1995-03-31 | 1996-02-27 | Xoma Corporation | Method of treating conditions associated with burn injuries |
| JP2000510845A (ja) * | 1996-05-10 | 2000-08-22 | ゾーマ コーポレイション | ヒト髄膜炎菌血症のためのｂｐｉタンパク質産物の治療用途 |
| US5741779A (en) | 1996-05-10 | 1998-04-21 | Xoma Corporation | Antithrombotic materials and methods |
| JP2000511190A (ja) * | 1996-05-23 | 2000-08-29 | ゾーマ コーポレイション | 外傷に起因する出血に見舞われたヒトにおけるｂｐｉタンパク質産物の治療用途 |
| US5888973A (en) | 1996-08-09 | 1999-03-30 | Xoma Corporation | Anti-chlamydial uses of BPI protein products |
| US6482796B2 (en) | 1996-11-01 | 2002-11-19 | Xoma Corporation | Therapeutic uses of N-terminal BPI protein products in ANCA-positive patients |
| EP1304118A3 (de) * | 1996-11-01 | 2004-01-14 | XOMA Technology Ltd. | Therapeutische Verwendung von BPI Proteineprodukten |
| US6093573A (en) * | 1997-06-20 | 2000-07-25 | Xoma | Three-dimensional structure of bactericidal/permeability-increasing protein (BPI) |
| US6013631A (en) * | 1998-06-19 | 2000-01-11 | Xoma Corporation | Bactericidal/permeability-increasing protein (BPI) deletion analogs |
| EP1741440A1 (de) | 2005-07-08 | 2007-01-10 | Mellitus S.L. | Verwendung von BPI-proteine zur Behandlung von stoffwechselbedingten Erkrankungen und Herzkreislaufstörungen |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5171739A (en) * | 1989-02-14 | 1992-12-15 | Incyte Pharmaceuticals, Inc. | Treatment of endotoxin-associated shock and preventation thereof using a BPI protein |
| AU9127591A (en) * | 1990-12-03 | 1992-06-25 | New York University | Biologically active bactericidal/permeability-increasing protein fragments |
-
1994
- 1994-03-11 EP EP94910876A patent/EP0690721B1/de not_active Expired - Lifetime
- 1994-03-11 DE DE69410254T patent/DE69410254T2/de not_active Expired - Fee Related
- 1994-03-11 ES ES94910876T patent/ES2119185T3/es not_active Expired - Lifetime
- 1994-03-11 AT AT94910876T patent/ATE165976T1/de not_active IP Right Cessation
- 1994-03-11 AU AU63618/94A patent/AU6361894A/en not_active Abandoned
- 1994-03-11 WO PCT/US1994/002463 patent/WO1994020129A1/en not_active Ceased
- 1994-03-11 DK DK94910876T patent/DK0690721T3/da active
- 1994-03-11 CA CA002157925A patent/CA2157925C/en not_active Expired - Fee Related
-
1998
- 1998-08-07 GR GR980401798T patent/GR3027620T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK0690721T3 (da) | 1999-03-08 |
| WO1994020129A1 (en) | 1994-09-15 |
| DE69410254D1 (de) | 1998-06-18 |
| GR3027620T3 (en) | 1998-11-30 |
| DE69410254T2 (de) | 1998-12-17 |
| EP0690721A1 (de) | 1996-01-10 |
| HK1010983A1 (en) | 1999-07-02 |
| CA2157925A1 (en) | 1994-09-15 |
| ES2119185T3 (es) | 1998-10-01 |
| EP0690721B1 (de) | 1998-05-13 |
| AU6361894A (en) | 1994-09-26 |
| CA2157925C (en) | 2000-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |