JP2002518011A - 殺菌性／透過性増加タンパク質（ｂｐｉ）欠失アナログ - Google Patents
殺菌性／透過性増加タンパク質（ｂｐｉ）欠失アナログInfo
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- JP2002518011A JP2002518011A JP2000554853A JP2000554853A JP2002518011A JP 2002518011 A JP2002518011 A JP 2002518011A JP 2000554853 A JP2000554853 A JP 2000554853A JP 2000554853 A JP2000554853 A JP 2000554853A JP 2002518011 A JP2002518011 A JP 2002518011A
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4742—Bactericidal/Permeability-increasing protein [BPI]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/099,725 | 1998-06-19 | ||
| US09/099,725 US6013631A (en) | 1998-06-19 | 1998-06-19 | Bactericidal/permeability-increasing protein (BPI) deletion analogs |
| PCT/US1999/013860 WO1999066044A1 (en) | 1998-06-19 | 1999-06-18 | Bactericidal/permeability-increasing protein (bpi) deletion analogs |
Publications (2)
| Publication Number | Publication Date |
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| JP2002518011A true JP2002518011A (ja) | 2002-06-25 |
| JP2002518011A5 JP2002518011A5 (enExample) | 2006-06-29 |
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| JP2000554853A Pending JP2002518011A (ja) | 1998-06-19 | 1999-06-18 | 殺菌性／透過性増加タンパク質（ｂｐｉ）欠失アナログ |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US6013631A (enExample) |
| EP (1) | EP1086230A1 (enExample) |
| JP (1) | JP2002518011A (enExample) |
| CN (1) | CN1273598C (enExample) |
| AU (1) | AU755624B2 (enExample) |
| CA (1) | CA2331880A1 (enExample) |
| MX (1) | MXPA00011398A (enExample) |
| NZ (1) | NZ508816A (enExample) |
| WO (1) | WO1999066044A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2004075913A1 (ja) * | 2003-02-28 | 2006-06-01 | 中外製薬株式会社 | タンパク質含有安定化製剤 |
| CN115777018A (zh) * | 2020-07-10 | 2023-03-10 | 株式会社绿十字 | 用于产生水痘-带状疱疹病毒表面蛋白抗原的方法 |
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| US5198541A (en) * | 1987-08-11 | 1993-03-30 | New York University | Dna encoding bactericidal/permeability-increasing proteins |
| US6013631A (en) * | 1998-06-19 | 2000-01-11 | Xoma Corporation | Bactericidal/permeability-increasing protein (BPI) deletion analogs |
| EP1181039A2 (en) * | 1999-05-24 | 2002-02-27 | Xoma (US) LLC | Therapeutic uses of bpi protein products in humans with otitis media with effusion |
| CA2430588A1 (en) * | 2000-12-01 | 2002-07-18 | Xoma Technology Ltd. | Modulation of pericyte proliferation using bpi protein products or bpi inhibitors |
| WO2004033693A1 (en) | 2002-03-29 | 2004-04-22 | Xoma Technology Ltd. | Methods vectors plasmids and methods for increasing expression of recombinant polypeptides |
| JP2008541746A (ja) * | 2005-06-03 | 2008-11-27 | ビオヴィトルム・アクチボラゲット（プブリクト） | 新規プロセス |
| EP1741440A1 (en) | 2005-07-08 | 2007-01-10 | Mellitus S.L. | Use of BPI protein for the treatment of disorders of the metabolism and cardiovascular disorders |
| US8338376B2 (en) * | 2006-10-20 | 2012-12-25 | Biogen Idec Ma Inc. | Compositions comprising variant LT-B-R-IG fusion proteins |
| WO2008112325A2 (en) * | 2007-03-15 | 2008-09-18 | Biogen Idec Ma Inc. | Treatment of autoimmune disorders |
| CN103648515B (zh) | 2011-04-05 | 2018-01-02 | 达纳-法伯癌症研究所有限公司 | 作为辐射缓和剂和辐射防护剂的bpi和其同源物 |
| GB201319621D0 (en) | 2013-11-06 | 2013-12-18 | Norwegian University Of Science And Technology | Antimicrobial agents and their use in therapy |
| GB201319620D0 (en) | 2013-11-06 | 2013-12-18 | Norwegian University Of Science And Technology | Immunosuppressive agents and their use in therapy |
| CN115947868A (zh) * | 2022-09-28 | 2023-04-11 | 安君(北京)基因科技有限责任公司 | Cxcl-bpi融合蛋白及其用途 |
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| US5198541A (en) * | 1987-08-11 | 1993-03-30 | New York University | Dna encoding bactericidal/permeability-increasing proteins |
| US5576292A (en) * | 1987-08-11 | 1996-11-19 | New York University | Biologically active bactericidal/permeability-increasing protein fragments |
| US5334584A (en) * | 1989-02-14 | 1994-08-02 | Incyte Pharamaceuticals, Inc. | Recombinant, non-glycosylated bpi protein and uses thereof |
| US5234912A (en) * | 1989-02-14 | 1993-08-10 | Incyte Pharmaceuticals, Inc. | Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof |
| US5089274A (en) * | 1989-02-14 | 1992-02-18 | Incyte Pharmaceuticals, Inc. | Use of bactericidal/permeability increasing protein or biologically active analogs thereof to treat endotoxin-related disorders |
| US5171739A (en) * | 1989-02-14 | 1992-12-15 | Incyte Pharmaceuticals, Inc. | Treatment of endotoxin-associated shock and preventation thereof using a BPI protein |
| US5308834A (en) * | 1989-02-14 | 1994-05-03 | Incyte Pharmaceuticals, Inc. | Treatment of endotoxin-associated shock and prevention thereof using a BPI protein |
| US5770694A (en) * | 1990-08-13 | 1998-06-23 | Incyte Pharmaceuticals, Inc. | Genetically engineered BPI variant proteins |
| DE69128968T2 (de) * | 1990-12-03 | 1998-10-08 | Univ New York | Biologisch aktive bakterizide/permeabilitätserhöhende proteinbruchstücke |
| JPH07502642A (ja) * | 1991-09-26 | 1995-03-23 | インサイト ファーマシューティカルズ，インコーポレイテッド | 新規な形態のリポ糖結合性タンパク質（ｌｂｐ） |
| AU669723B2 (en) * | 1992-05-19 | 1996-06-20 | Xoma Corporation | Improved methods for the preparation of endotoxin-binding proteins |
| US5643570A (en) * | 1992-05-19 | 1997-07-01 | Xoma Corporation | BPI-immunoglobulin fusion proteins |
| US5488034A (en) * | 1993-02-02 | 1996-01-30 | Xoma Corporation | Pharmaceutical composition comprising BPI proteins |
| US5420019A (en) * | 1993-02-02 | 1995-05-30 | Xoma Corporation | Stable bactericidal/permeability-increasing protein muteins |
| CA2152925A1 (en) | 1993-02-18 | 1994-09-01 | Raymond Baker | Azacyclic compounds compositions containing them and their use as tachykinin antagonists |
| US5348942A (en) * | 1993-03-12 | 1994-09-20 | Xoma Corporation | Therapeutic uses of bactericidal/permeability increasing protein products |
| WO1994020129A1 (en) * | 1993-03-12 | 1994-09-15 | Xoma Corporation | Treatment of mycobacterial diseases by administration of bactericidal/permeability-increasing protein products |
| CA2158058C (en) * | 1993-03-12 | 2000-08-01 | Roger G. Ii Little | Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof |
| US5733872A (en) * | 1993-03-12 | 1998-03-31 | Xoma Corporation | Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof |
| US5652332A (en) * | 1993-03-12 | 1997-07-29 | Xoma | Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof |
| ES2157981T3 (es) * | 1993-03-12 | 2001-09-01 | Xoma Technology Ltd | Usos terapeuticos de productos proteicos bactericidas/aumentadores de la permeabilidad. |
| WO1994021280A1 (en) * | 1993-03-22 | 1994-09-29 | Incyte Pharmaceuticals, Inc. | Use of bactericidal/permeability increasing protein and lipopolysaccharide binding protein levels and ratios thereof in diagnosis |
| JPH08511682A (ja) * | 1993-04-30 | 1996-12-10 | インサイト ファーマシューティカルズ，インク． | 組み換えｂｐｉ蛋白およびｌｂｐ蛋白、それをコードする核酸分子、その生産方法並びにそれらの使用 |
| US5731415A (en) * | 1993-06-17 | 1998-03-24 | Xoma Corporation | Lipopolysaccharide binding protein derivatives |
| DE69431922T2 (de) * | 1993-07-02 | 2003-11-13 | Incyte Pharmaceuticals, Inc. | Glycosilierte und nichtglycolisierte bakterizide/die permeabilität erhoehende proteine und methoden zu ihrer herstellung |
| WO1995002414A1 (en) * | 1993-07-14 | 1995-01-26 | Xoma Corporation | Method for potentiating bpi protein product bactericidal activity by administration of lbp protein products |
| US5770561A (en) * | 1993-07-14 | 1998-06-23 | Xoma Corporation | Method for potentiating BPI protein product bactericidal activity by administration of LBP protein products |
| CN1133634A (zh) * | 1993-09-22 | 1996-10-16 | 爱克斯欧玛公司 | 定量体液中的bpi的方法 |
| US5466580A (en) * | 1993-09-22 | 1995-11-14 | Xoma Corporation | Method for quantifying BPI in body fluids |
| NZ275205A (en) * | 1993-09-22 | 1998-03-25 | Xoma Corp | Use of bactericidal/permeability-increasing protein in treating gram-negative bacterial infection |
| CA2173611C (en) * | 1993-10-05 | 2005-07-26 | Paul A. M. Van Leeuwen | Method of treating depressed reticuloendothelial system function |
| DK0754050T3 (da) * | 1994-01-14 | 2002-10-21 | Xoma Technology Ltd | Anti-gram-positive bakterielle fremgangsmåder og materialer |
| CN1112933C (zh) * | 1994-01-14 | 2003-07-02 | 爱克索马技术有限公司 | 抗真菌的方法和物质 |
| US5643875A (en) * | 1994-01-24 | 1997-07-01 | Friedmann; Nadav | Human therapeutic uses of bactericidal/permeability increasing (BPI) protein products |
| US5484705A (en) * | 1994-01-24 | 1996-01-16 | Xoma Corporation | Method for quantifying lipopolysaccharide binding protein |
| US5447913A (en) * | 1994-03-11 | 1995-09-05 | Xoma Corporation | Therapeutic uses of bactericidal/permeability-increasing protein dimer products |
| US5786324A (en) * | 1994-03-24 | 1998-07-28 | Regents Of The University Of Minnesota | Synthetic peptides with bactericidal activity and endotoxin neutralizing activity for gram negative bacteria and methods for their use |
| US5578568A (en) * | 1994-04-22 | 1996-11-26 | Xoma Corporation | Method of treating conditions associated with intestinal ischemia/reperfusion |
| US5532216A (en) * | 1994-06-24 | 1996-07-02 | Incyte Pharmaceuticals, Inc. | Neutralization of non-lipopolysaccharide compounds by bactericidal/permeability-increasing protein |
| US5646114A (en) * | 1994-07-11 | 1997-07-08 | Xoma Corporation | Anti-protozoan methods |
| DE69532302D1 (de) * | 1994-09-15 | 2004-01-22 | Xoma Technology Ltd | Peptide gegen pilzen |
| US5912228A (en) * | 1995-01-13 | 1999-06-15 | Xoma Corporation | Therapeutic compositions comprising bactericidal/permeability-increasing (BPI) protein products |
| US5494896A (en) * | 1995-03-31 | 1996-02-27 | Xoma Corporation | Method of treating conditions associated with burn injuries |
| WO1997004008A1 (en) * | 1995-07-20 | 1997-02-06 | Xoma Corporation | Anti-fungal peptides |
| EP0861088A1 (en) * | 1995-11-14 | 1998-09-02 | Xoma Corporation | Bactericidal permeability increasing protein (bpi) for treating conditions associated with corneal injury |
| US5686414A (en) * | 1995-11-14 | 1997-11-11 | Xoma Corporation | Methods of treating conditions associated with corneal transplantation |
| CA2253837C (en) * | 1996-05-10 | 2002-07-02 | Xoma Corporation | Therapeutic uses of bpi protein products for human meningococcemia |
| US5741779A (en) * | 1996-05-10 | 1998-04-21 | Xoma Corporation | Antithrombotic materials and methods |
| WO1997044056A1 (en) * | 1996-05-23 | 1997-11-27 | Xoma Corporation | Therapeutic uses of bpi protein products in humans with hemorrhage due to trauma |
| US5888973A (en) * | 1996-08-09 | 1999-03-30 | Xoma Corporation | Anti-chlamydial uses of BPI protein products |
| ATE229812T1 (de) * | 1996-11-01 | 2003-01-15 | Xoma Technology Ltd | Therapeutische verwendung von bpi proteineprodukten bei patienten mit zystischer fibrose |
| US6013631A (en) * | 1998-06-19 | 2000-01-11 | Xoma Corporation | Bactericidal/permeability-increasing protein (BPI) deletion analogs |
-
1998
- 1998-06-19 US US09/099,725 patent/US6013631A/en not_active Expired - Lifetime
-
1999
- 1999-06-18 CA CA002331880A patent/CA2331880A1/en not_active Abandoned
- 1999-06-18 AU AU46976/99A patent/AU755624B2/en not_active Ceased
- 1999-06-18 JP JP2000554853A patent/JP2002518011A/ja active Pending
- 1999-06-18 US US09/336,402 patent/US6087126A/en not_active Expired - Fee Related
- 1999-06-18 EP EP99930432A patent/EP1086230A1/en not_active Withdrawn
- 1999-06-18 WO PCT/US1999/013860 patent/WO1999066044A1/en not_active Ceased
- 1999-06-18 CN CNB998097268A patent/CN1273598C/zh not_active Expired - Fee Related
- 1999-06-18 MX MXPA00011398A patent/MXPA00011398A/es unknown
- 1999-06-18 NZ NZ508816A patent/NZ508816A/xx unknown
-
2000
- 2000-05-25 US US09/579,403 patent/US6599880B1/en not_active Expired - Fee Related
-
2003
- 2003-07-29 US US10/629,516 patent/US20050130889A1/en not_active Abandoned
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2004075913A1 (ja) * | 2003-02-28 | 2006-06-01 | 中外製薬株式会社 | タンパク質含有安定化製剤 |
| CN115777018A (zh) * | 2020-07-10 | 2023-03-10 | 株式会社绿十字 | 用于产生水痘-带状疱疹病毒表面蛋白抗原的方法 |
| JP2023533160A (ja) * | 2020-07-10 | 2023-08-02 | グリーン・クロス・コーポレイション | 水痘帯状疱疹ウイルス表面タンパク質抗原を生産するための方法 |
| JP7487858B2 (ja) | 2020-07-10 | 2024-05-21 | グリーン・クロス・コーポレイション | 水痘帯状疱疹ウイルス表面タンパク質抗原を生産するための方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1312858A (zh) | 2001-09-12 |
| CN1273598C (zh) | 2006-09-06 |
| CA2331880A1 (en) | 1999-12-23 |
| MXPA00011398A (es) | 2003-04-22 |
| EP1086230A1 (en) | 2001-03-28 |
| AU4697699A (en) | 2000-01-05 |
| NZ508816A (en) | 2003-03-28 |
| US6087126A (en) | 2000-07-11 |
| AU755624B2 (en) | 2002-12-19 |
| WO1999066044A1 (en) | 1999-12-23 |
| US6013631A (en) | 2000-01-11 |
| US20050130889A1 (en) | 2005-06-16 |
| US6599880B1 (en) | 2003-07-29 |
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