JP2002516568A5 - - Google Patents

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Publication number
JP2002516568A5
JP2002516568A5 JP1998538676A JP53867698A JP2002516568A5 JP 2002516568 A5 JP2002516568 A5 JP 2002516568A5 JP 1998538676 A JP1998538676 A JP 1998538676A JP 53867698 A JP53867698 A JP 53867698A JP 2002516568 A5 JP2002516568 A5 JP 2002516568A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998538676A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002516568A (ja
Filing date
Publication date
Priority claimed from US09/033,428 external-priority patent/US6254862B1/en
Application filed filed Critical
Publication of JP2002516568A publication Critical patent/JP2002516568A/ja
Publication of JP2002516568A5 publication Critical patent/JP2002516568A5/ja
Ceased legal-status Critical Current

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JP53867698A 1997-03-03 1998-03-03 α−フェトタンパク質を発現する細胞に特異的なアデノウイルスベクターおよびその使用の方法 Ceased JP2002516568A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US3959797P 1997-03-03 1997-03-03
US60/039,597 1997-03-03
US09/033,428 1998-03-02
US09/033,428 US6254862B1 (en) 1997-03-03 1998-03-02 Adenovirus vectors specific for cells expressing alpha-fetoprotein and methods of use thereof
PCT/US1998/004084 WO1998039465A2 (en) 1997-03-03 1998-03-03 Adenovirus vectors specific for cells expressing alpha-fetoprotein and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2002516568A JP2002516568A (ja) 2002-06-04
JP2002516568A5 true JP2002516568A5 (https=) 2005-11-10

Family

ID=21906330

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53867698A Ceased JP2002516568A (ja) 1997-03-03 1998-03-03 α−フェトタンパク質を発現する細胞に特異的なアデノウイルスベクターおよびその使用の方法

Country Status (10)

Country Link
US (2) US6254862B1 (https=)
EP (1) EP0972063B1 (https=)
JP (1) JP2002516568A (https=)
KR (1) KR20000075924A (https=)
CN (1) CN100390292C (https=)
AT (1) ATE385256T1 (https=)
AU (1) AU745560B2 (https=)
CA (1) CA2282706C (https=)
DE (1) DE69839071T2 (https=)
WO (1) WO1998039465A2 (https=)

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US6254862B1 (en) * 1997-03-03 2001-07-03 Calydon, Inc. Adenovirus vectors specific for cells expressing alpha-fetoprotein and methods of use thereof
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US6495130B1 (en) * 1998-12-30 2002-12-17 Calydon, Inc. Target cell-specific adenoviral vectors containing E3 and methods of use thereof
US20060024273A1 (en) * 1998-12-30 2006-02-02 Henderson Daniel R Target cell-specific adenoviral vectors containing E3 and methods of use thereof
US7589069B1 (en) * 1999-07-12 2009-09-15 Saint Louis University Replication-competent anti-cancer vectors
US6627190B2 (en) * 1999-07-12 2003-09-30 Saint Louis University Recombinant adenovirus vectors that are replication-competent in tert-expressing cells
AU1071701A (en) 1999-09-29 2001-04-30 Trustees Of The University Of Pennsylvania, The Methods for rapid peg-modification of viral vectors, compositions for enhanced gene transduction, compositions with enhanced physical stability, and uses therefor
CA2403795A1 (en) * 2000-03-21 2001-09-27 The University Of Virginia Patent Foundation Osteocalcin promoter directed adenovirus replicaton for therapy
US6692736B2 (en) 2000-03-24 2004-02-17 Cell Genesys, Inc. Cell-specific adenovirus vectors comprising an internal ribosome entry site
ATE419338T1 (de) 2000-03-24 2009-01-15 Cell Genesys Inc Menschliche zellspezifische urotheliale regulatorische sequenzen der transkription des uroplakins, dessen vektoren und verwendungsverfahren
US6911200B2 (en) * 2000-03-24 2005-06-28 Cell Genesys, Inc. Methods of treating neoplasia with combination of target-cell specific adenovirus, chemotherapy and radiation
US7048920B2 (en) 2000-03-24 2006-05-23 Cell Genesys, Inc. Recombinant oncolytic adenovirus for human melanoma
US6673614B2 (en) 2000-06-27 2004-01-06 Cell Genesys, Inc. Rapid methods and kits for detection and semi-quantitation of anti-adenovirus antibody
AU2003222427B8 (en) 2000-11-17 2010-04-29 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
US8071740B2 (en) 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
WO2002068627A2 (en) * 2001-02-23 2002-09-06 Novartis Ag Vector constucts
CA2463816C (en) 2001-10-19 2014-07-08 Vascular Biogenics Ltd. Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
US20030086903A1 (en) * 2001-11-02 2003-05-08 Genvec, Inc. Therapeutic regimen for treating cancer
EP1605053A1 (en) * 2002-03-26 2005-12-14 Oncolytics Biotech Inc. Use of adenoviruses mutated in the VA genes for cancer treatment
US7364727B2 (en) * 2002-07-22 2008-04-29 Cell Genesys, Inc. Metastatic colon cancer specific promoter and uses thereof
RU2393221C2 (ru) * 2002-10-15 2010-06-27 Пер Сонне ХОЛЬМ Аденовирус с обращенной генной экспрессией и его применение
WO2005017149A1 (en) * 2003-06-03 2005-02-24 Cell Genesys, Inc. Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site
US20050136035A1 (en) * 2003-06-03 2005-06-23 Derek Ko Cell specific replication-competent viral vectors comprising a self processing peptide cleavage site
US20050186178A1 (en) * 2003-08-28 2005-08-25 Ennist David L. Oncolytic adenoviral vectors encoding GM-CSF
CN100420742C (zh) * 2003-09-29 2008-09-24 中国人民解放军军事医学科学院基础医学研究所 一种肝癌靶向性溶瘤腺病毒，其制备方法及用途
US7482156B2 (en) 2003-10-15 2009-01-27 Cell Genesys, Inc. Hepatocellular carcinoma specific promoter and uses thereof
DE602004025726D1 (de) * 2003-11-14 2010-04-08 Genvec Inc Pharmazeutische verbindung zur behandlung von lokal fortgeschrittenem primär inoperablen pankreaskarzinom (lapc).
US7473418B2 (en) 2004-03-25 2009-01-06 Cell Genesys, Inc. Pan cancer oncolytic vectors and methods of use thereof
ES2292271B1 (es) * 2004-05-20 2009-02-16 Proyecto De Biomedicina Cima, S.L. Un vector hibrido adenovirus-alfavirus para la administracion eficaz y expresion de genes terapeuticos en celulas tumorales.
TWI293307B (en) * 2004-09-30 2008-02-11 Ind Tech Res Inst A liver-specific chimeric regulatory sequence and use thereof
DE102005055128B4 (de) * 2005-11-15 2015-04-02 Universität Rostock Viraler Vektor, dessen Verwendung zur Therapie von Leberzellkarzinomen und pharmazeutische Mittel umfassend den Vektor
EP1900749A1 (en) * 2006-09-12 2008-03-19 Institut National De La Sante Et De La Recherche Medicale (Inserm) Nucleic acids for expressing a polynucleotide of interest in mammalian cancer cells
US20080089890A1 (en) * 2006-09-29 2008-04-17 Canji, Inc. Methods of polypeptide production
CN102268457B (zh) * 2007-04-23 2013-06-26 深圳益世康宁生物科技有限公司 一种afp重组腺相关病毒载体及其构建方法与应用
US9782565B2 (en) 2008-10-01 2017-10-10 Covidien Lp Endoscopic ultrasound-guided biliary access system
US11298113B2 (en) 2008-10-01 2022-04-12 Covidien Lp Device for needle biopsy with integrated needle protection
US9332973B2 (en) 2008-10-01 2016-05-10 Covidien Lp Needle biopsy device with exchangeable needle and integrated needle protection
US9186128B2 (en) 2008-10-01 2015-11-17 Covidien Lp Needle biopsy device
US8968210B2 (en) 2008-10-01 2015-03-03 Covidien LLP Device for needle biopsy with integrated needle protection
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