JP2002514204A - 粘着性、抗菌性および／または修復的象牙質刺激歯科用組成物およびこれらの組成物の生成および使用方法 - Google Patents
粘着性、抗菌性および／または修復的象牙質刺激歯科用組成物およびこれらの組成物の生成および使用方法Info
- Publication number
- JP2002514204A JP2002514204A JP53669998A JP53669998A JP2002514204A JP 2002514204 A JP2002514204 A JP 2002514204A JP 53669998 A JP53669998 A JP 53669998A JP 53669998 A JP53669998 A JP 53669998A JP 2002514204 A JP2002514204 A JP 2002514204A
- Authority
- JP
- Japan
- Prior art keywords
- dental composition
- composition
- antimicrobial
- adhesive
- methacrylate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- -1 alkyl methacrylate Chemical compound 0.000 claims abstract description 44
- 239000004599 antimicrobial Substances 0.000 claims abstract description 23
- 244000005700 microbiome Species 0.000 claims abstract description 14
- 239000003242 anti bacterial agent Substances 0.000 claims abstract description 12
- 238000011065 in-situ storage Methods 0.000 claims abstract description 9
- 239000003505 polymerization initiator Substances 0.000 claims abstract description 7
- 150000008044 alkali metal hydroxides Chemical class 0.000 claims abstract description 5
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- 229910000287 alkaline earth metal oxide Inorganic materials 0.000 claims abstract description 4
- 229940088710 antibiotic agent Drugs 0.000 claims abstract description 4
- 238000006116 polymerization reaction Methods 0.000 claims description 34
- 239000000463 material Substances 0.000 claims description 19
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- WMFOQBRAJBCJND-UHFFFAOYSA-M Lithium hydroxide Chemical compound [Li+].[OH-] WMFOQBRAJBCJND-UHFFFAOYSA-M 0.000 claims description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 6
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- 238000007789 sealing Methods 0.000 claims description 5
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- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims description 4
- QVQLCTNNEUAWMS-UHFFFAOYSA-N barium oxide Chemical compound [Ba]=O QVQLCTNNEUAWMS-UHFFFAOYSA-N 0.000 claims description 4
- YWILDZMVBIMXID-KGHBUBBXSA-N (4s,4as,5as,6s,12ar)-n-[[4-[n-(diaminomethylidene)carbamimidoyl]piperazin-1-yl]methyl]-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;dihydrochloride Chemical compound Cl.Cl.OC([C@@]1(O)C(=O)C=2[C@@H]([C@](C3=CC=CC(O)=C3C=2O)(C)O)C[C@H]1[C@@H](C1=O)N(C)C)=C1C(=O)NCN1CCN(C(=N)N=C(N)N)CC1 YWILDZMVBIMXID-KGHBUBBXSA-N 0.000 claims description 3
- YKXAYLPDMSGWEV-UHFFFAOYSA-N 4-hydroxybutyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCCCO YKXAYLPDMSGWEV-UHFFFAOYSA-N 0.000 claims description 3
- MIFYHUACUWQUKT-UHFFFAOYSA-N Isopenicillin N Natural products OC(=O)C1C(C)(C)SC2C(NC(=O)CCCC(N)C(O)=O)C(=O)N21 MIFYHUACUWQUKT-UHFFFAOYSA-N 0.000 claims description 3
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- MINDHVHHQZYEEK-HBBNESRFSA-N mupirocin Chemical compound C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC(O)=O)OC1 MINDHVHHQZYEEK-HBBNESRFSA-N 0.000 claims description 3
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- QAQSNXHKHKONNS-UHFFFAOYSA-N 1-ethyl-2-hydroxy-4-methyl-6-oxopyridine-3-carboxamide Chemical compound CCN1C(O)=C(C(N)=O)C(C)=CC1=O QAQSNXHKHKONNS-UHFFFAOYSA-N 0.000 claims description 2
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 claims description 2
- 229960004328 azidocillin Drugs 0.000 claims description 2
- RQPZNWPYLFFXCP-UHFFFAOYSA-L barium dihydroxide Chemical compound [OH-].[OH-].[Ba+2] RQPZNWPYLFFXCP-UHFFFAOYSA-L 0.000 claims description 2
- 229910001863 barium hydroxide Inorganic materials 0.000 claims description 2
- 229960000686 benzalkonium chloride Drugs 0.000 claims description 2
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 claims description 2
- BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 claims description 2
- 239000000292 calcium oxide Substances 0.000 claims description 2
- ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 claims description 2
- 238000005520 cutting process Methods 0.000 claims description 2
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- TYQXKHPOXXXCTP-CSLYCKPJSA-N erythromycin A 2'-propanoate Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)OC(=O)CC)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 TYQXKHPOXXXCTP-CSLYCKPJSA-N 0.000 claims description 2
- VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 claims description 2
- 239000000347 magnesium hydroxide Substances 0.000 claims description 2
- 229910001862 magnesium hydroxide Inorganic materials 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- XDWLRMBWIWKFNC-HNQUOIGGSA-N nifurprazine Chemical compound N1=NC(N)=CC=C1\C=C\C1=CC=C([N+]([O-])=O)O1 XDWLRMBWIWKFNC-HNQUOIGGSA-N 0.000 claims description 2
- 150000002923 oximes Chemical class 0.000 claims description 2
- 150000003014 phosphoric acid esters Chemical class 0.000 claims description 2
- UUCCCPNEFXQJEL-UHFFFAOYSA-L strontium dihydroxide Chemical compound [OH-].[OH-].[Sr+2] UUCCCPNEFXQJEL-UHFFFAOYSA-L 0.000 claims description 2
- 229910001866 strontium hydroxide Inorganic materials 0.000 claims description 2
- 230000001678 irradiating effect Effects 0.000 claims 6
- 125000000217 alkyl group Chemical group 0.000 claims 3
- WDFFWUVELIFAOP-UHFFFAOYSA-N 2,6-difluoro-4-nitroaniline Chemical compound NC1=C(F)C=C([N+]([O-])=O)C=C1F WDFFWUVELIFAOP-UHFFFAOYSA-N 0.000 claims 2
- AOOOGDNZPXWIMU-UHFFFAOYSA-N 3-hydroxypropyl 2-methylprop-2-enoate phosphoric acid Chemical compound P(=O)(O)(O)O.C(C(=C)C)(=O)OCCCO AOOOGDNZPXWIMU-UHFFFAOYSA-N 0.000 claims 2
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 claims 2
- YCMLQMDWSXFTIF-UHFFFAOYSA-N 2-methylbenzenesulfonimidic acid Chemical compound CC1=CC=CC=C1S(N)(=O)=O YCMLQMDWSXFTIF-UHFFFAOYSA-N 0.000 claims 1
- UMAFYWRLCSIUBO-UHFFFAOYSA-N 4-hydroxybutyl 2-methylprop-2-enoate phosphoric acid Chemical compound P(=O)(O)(O)O.C(C(=C)C)(=O)OCCCCO UMAFYWRLCSIUBO-UHFFFAOYSA-N 0.000 claims 1
- 229950008560 almecillin Drugs 0.000 claims 1
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- 206010062544 Tooth fracture Diseases 0.000 description 1
- XUBKPYAWPSXPDZ-UHFFFAOYSA-N [Ba].OS(O)(=O)=O Chemical compound [Ba].OS(O)(=O)=O XUBKPYAWPSXPDZ-UHFFFAOYSA-N 0.000 description 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 125000003282 alkyl amino group Chemical group 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 125000005605 benzo group Chemical group 0.000 description 1
- RWCCWEUUXYIKHB-UHFFFAOYSA-N benzophenone Chemical compound C=1C=CC=CC=1C(=O)C1=CC=CC=C1 RWCCWEUUXYIKHB-UHFFFAOYSA-N 0.000 description 1
- 239000012965 benzophenone Substances 0.000 description 1
- 235000019400 benzoyl peroxide Nutrition 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 239000000805 composite resin Substances 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 210000003298 dental enamel Anatomy 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- LSXWFXONGKSEMY-UHFFFAOYSA-N di-tert-butyl peroxide Chemical compound CC(C)(C)OOC(C)(C)C LSXWFXONGKSEMY-UHFFFAOYSA-N 0.000 description 1
- VFHVQBAGLAREND-UHFFFAOYSA-N diphenylphosphoryl-(2,4,6-trimethylphenyl)methanone Chemical compound CC1=CC(C)=CC(C)=C1C(=O)P(=O)(C=1C=CC=CC=1)C1=CC=CC=C1 VFHVQBAGLAREND-UHFFFAOYSA-N 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000005530 etching Methods 0.000 description 1
- STVZJERGLQHEKB-UHFFFAOYSA-N ethylene glycol dimethacrylate Chemical compound CC(=C)C(=O)OCCOC(=O)C(C)=C STVZJERGLQHEKB-UHFFFAOYSA-N 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 239000000665 guar gum Substances 0.000 description 1
- 235000010417 guar gum Nutrition 0.000 description 1
- 229960002154 guar gum Drugs 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- BHEPBYXIRTUNPN-UHFFFAOYSA-N hydridophosphorus(.) (triplet) Chemical group [PH] BHEPBYXIRTUNPN-UHFFFAOYSA-N 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 1
- 230000009610 hypersensitivity Effects 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000028709 inflammatory response Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000008011 inorganic excipient Substances 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229910000000 metal hydroxide Inorganic materials 0.000 description 1
- 150000004692 metal hydroxides Chemical class 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 229960002900 methylcellulose Drugs 0.000 description 1
- 235000010981 methylcellulose Nutrition 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- GYVGXEWAOAAJEU-UHFFFAOYSA-N n,n,4-trimethylaniline Chemical compound CN(C)C1=CC=C(C)C=C1 GYVGXEWAOAAJEU-UHFFFAOYSA-N 0.000 description 1
- XZSZONUJSGDIFI-UHFFFAOYSA-N n-(4-hydroxyphenyl)-2-methylprop-2-enamide Chemical compound CC(=C)C(=O)NC1=CC=C(O)C=C1 XZSZONUJSGDIFI-UHFFFAOYSA-N 0.000 description 1
- AUONHKJOIZSQGR-UHFFFAOYSA-N oxophosphane Chemical compound P=O AUONHKJOIZSQGR-UHFFFAOYSA-N 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 229940049954 penicillin Drugs 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- NHARPDSAXCBDDR-UHFFFAOYSA-N propyl 2-methylprop-2-enoate Chemical compound CCCOC(=O)C(C)=C NHARPDSAXCBDDR-UHFFFAOYSA-N 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000005067 remediation Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 229910052814 silicon oxide Inorganic materials 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 229910052712 strontium Inorganic materials 0.000 description 1
- CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 210000005239 tubule Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/70—Preparations for dentistry comprising inorganic additives
- A61K6/71—Fillers
- A61K6/76—Fillers comprising silicon-containing compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/60—Preparations for dentistry comprising organic or organo-metallic additives
- A61K6/69—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/70—Preparations for dentistry comprising inorganic additives
- A61K6/71—Fillers
Landscapes
- Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Dental Preparations (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/803,602 | 1997-02-19 | ||
| US08/803,602 US6071528A (en) | 1997-02-19 | 1997-02-19 | Adhesive antimicrobial and/or reparative dentin stimulating dental compositions and methods for forming and using such compositions |
| PCT/US1998/002503 WO1998036639A1 (en) | 1997-02-19 | 1998-02-09 | Adhesive, antimicrobial and/or reparative dentin stimulating dental compositions and methods for forming and using such compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002514204A true JP2002514204A (ja) | 2002-05-14 |
| JP2002514204A5 JP2002514204A5 (enExample) | 2005-10-06 |
Family
ID=25186976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP53669998A Ceased JP2002514204A (ja) | 1997-02-19 | 1998-02-09 | 粘着性、抗菌性および／または修復的象牙質刺激歯科用組成物およびこれらの組成物の生成および使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US6071528A (enExample) |
| EP (1) | EP0981273A4 (enExample) |
| JP (1) | JP2002514204A (enExample) |
| AU (1) | AU6322498A (enExample) |
| WO (1) | WO1998036639A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012087070A (ja) * | 2010-10-15 | 2012-05-10 | Tokuyama Dental Corp | 重合性単量体 |
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| AU3191599A (en) * | 1998-03-18 | 1999-10-11 | Lxr Biotechnology Inc. | Compositions containing lysophosphatidic acids which inhibit apoptosis and uses thereof |
| US6353041B1 (en) * | 1999-10-22 | 2002-03-05 | Kerr Corporation | Dental compositions |
| US6309221B1 (en) * | 2000-10-13 | 2001-10-30 | Ultradent Products, Inc. | Compositions, methods and kits for hemostasis and sealing of pulp during invasive dental procedures |
| US20040053201A1 (en) * | 2002-09-17 | 2004-03-18 | Dovgan Joseph S. | Antibacterial sponges for use in endodontic procedures and methods of use |
| US7288615B2 (en) * | 2003-03-14 | 2007-10-30 | Marquette University | Modified dental prosthesis |
| US7309232B2 (en) * | 2003-10-10 | 2007-12-18 | Dentigenix Inc. | Methods for treating dental conditions using tissue scaffolds |
| DE10359338B4 (de) * | 2003-12-17 | 2007-07-19 | Heraeus Kulzer Gmbh | Antimikrobieller Nanosilber-Zusatz für polymerisierbare Dentalmaterialien |
| US20070183986A1 (en) * | 2006-02-06 | 2007-08-09 | Ultradent Products, Inc. | Methods and systems for mixing a multi-part fluoride varnish composition |
| FR2898043B1 (fr) * | 2006-03-02 | 2008-06-06 | Rech S Tech Dentaires R T D Sa | Element prothetique dentaire antimicrobien et procede de fabrication |
| US7776010B2 (en) * | 2006-05-01 | 2010-08-17 | Ultradent Products, Inc. | Syringe-in-syringe hollow inner barrel/plunger with integral seal and rupturable membrane and related kits, systems, and methods |
| US8454558B2 (en) | 2007-02-09 | 2013-06-04 | Ultradent Products, Inc. | Syringe-in-syringe hollow inner barrel/plunger with integral seal and rupturable membrane and related kits, systems and methods |
| US8383163B2 (en) * | 2008-01-29 | 2013-02-26 | Ultradent Products, Inc. | Fluoride varnish compositions including an organo phosphoric acid adhesion promoting agent |
| US20100150985A1 (en) * | 2008-04-24 | 2010-06-17 | George Just | Dental Implant, Endodontic Instrument, and Dental Filling Material Coated with a Peptide-Based Antimicrobial and Methods of Using and Making the Same |
| US9028878B2 (en) | 2009-02-03 | 2015-05-12 | Microbion Corporation | Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses |
| CA2751386C (en) | 2009-02-03 | 2018-03-06 | Microbion Corporation | Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications |
| US9408393B2 (en) | 2010-02-03 | 2016-08-09 | Microbion Corporation | Bismuth-thiols as antiseptics for agricultural, industrial and other uses |
| US9486393B2 (en) * | 2009-12-18 | 2016-11-08 | Cao Group, Inc. | Single component tooth root sealer |
| EP2384733B1 (de) * | 2010-05-07 | 2016-07-27 | Ivoclar Vivadent AG | Antimikrobielle Dentalwerkstoffe |
| WO2013090204A2 (en) * | 2011-12-12 | 2013-06-20 | Loma Linda University | Composition and method for reducing bacterial biofilm formation in connection with a dental procedure |
| TWI630003B (zh) * | 2012-05-07 | 2018-07-21 | 國立成功大學 | 抗菌製劑及使用其製作一骨頭植入物的方法 |
| US10219986B2 (en) | 2015-03-04 | 2019-03-05 | Modern Ideas LLC | Stabilized calcium phosphate and methods of forming same |
| US9956314B2 (en) | 2016-01-26 | 2018-05-01 | Modern Ideas LLC | Adhesive for use with bone and bone-like structures |
| CA3015172A1 (en) | 2016-02-18 | 2017-08-24 | Privo Technologies, Inc. | Two-stage microparticle-based therapeutic delivery system and method |
| WO2018106912A1 (en) | 2016-12-08 | 2018-06-14 | The Board Of Regents Of The University Of Oklahoma | Compositions with doped titanium dioxide nanoparticles and methods of use |
| WO2018151849A1 (en) * | 2017-02-17 | 2018-08-23 | Privo Technologies, Inc. | Particle-based multi-layer therapeutic delivery device and method |
| US10478403B1 (en) | 2017-05-03 | 2019-11-19 | Privo Technologies, Inc. | Intraoperative topically-applied non-implantable rapid release patch |
| MX2021001276A (es) | 2018-07-31 | 2021-07-15 | Microbion Corp | Composiciones de bismuto-tiol y metodos para tratar heridas. |
| EP3829307A4 (en) | 2018-07-31 | 2022-08-03 | Microbion Corporation | BISMUTH-THIOL COMPOSITIONS AND METHODS OF USE |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3997504A (en) * | 1971-04-01 | 1976-12-14 | Plymale Richard W | Composition and method for treating teeth |
| US3882600A (en) * | 1971-04-01 | 1975-05-13 | Richard W Plymale | Composition in method for treating teeth |
| GB1569021A (en) * | 1976-03-17 | 1980-06-11 | Kuraray Co | Adhesive cementing agents containing partial phosphonic orphosphonic acid esters |
| JPS53134037A (en) * | 1977-04-27 | 1978-11-22 | Kuraray Co Ltd | Adhesive for human hard tissue with good adhesiveness |
| DE3041904C2 (de) * | 1980-11-06 | 1984-11-22 | Henkel KGaA, 4000 Düsseldorf | Borverbindungen enthaltende lagerstabile Reaktionsklebstoffe |
| JPS57134493A (en) * | 1981-02-12 | 1982-08-19 | Sankin Kogyo Kk | Phosphoric ester derivative |
| US4669983A (en) * | 1981-02-13 | 1987-06-02 | Minnesota Mining And Manufacturing Company | Dentin and enamel adhesive |
| US4670576A (en) * | 1981-02-13 | 1987-06-02 | Minnesota Mining And Manufacturing Company | Polymerizable phosphorus esters |
| US5177121A (en) * | 1981-02-13 | 1993-01-05 | Minnesota Mining And Manufacturing Company | Dentin and enamel adhesive |
| US4929746A (en) * | 1981-02-13 | 1990-05-29 | Minnesota Mining And Manufacturing Company | Dentin and enamel adhesive |
| US4539382A (en) * | 1981-07-29 | 1985-09-03 | Kuraray Co., Ltd. | Adhesive composition |
| US4650847A (en) * | 1981-07-29 | 1987-03-17 | Kuraray Co., Ltd. | Adhesive composition |
| JPS59135272A (ja) * | 1983-01-21 | 1984-08-03 | Kuraray Co Ltd | 接着剤 |
| JPS59137404A (ja) * | 1983-01-27 | 1984-08-07 | Kuraray Co Ltd | 歯科用接着剤 |
| JPS59140276A (ja) * | 1983-01-31 | 1984-08-11 | Kuraray Co Ltd | 新規な接着剤 |
| JPS6045510A (ja) * | 1983-08-23 | 1985-03-12 | Kuraray Co Ltd | 歯科用接着剤 |
| US4966934A (en) * | 1984-11-29 | 1990-10-30 | Dentsply Research & Development Corp. | Biological compatible adhesive containing a phosphorous adhesion promoter and accelerator |
| US4657941A (en) * | 1984-11-29 | 1987-04-14 | Dentsply Research & Development Corp. | Biologically compatible adhesive containing a phosphorus adhesion promoter and a sulfinic accelerator |
| JPS61151104A (ja) * | 1984-12-25 | 1986-07-09 | Tokuyama Soda Co Ltd | 歯科用接着性被膜形成材 |
| CA1292338C (en) * | 1985-01-29 | 1991-11-19 | Dentsply International Inc. | Non-toxic organic compositions and calcium hydroxide compositions thereof |
| DE3536076A1 (de) * | 1985-10-09 | 1987-04-09 | Muehlbauer Ernst Kg | Polymerisierbare zementmischungen |
| DE3536077A1 (de) * | 1985-10-09 | 1987-04-09 | Muehlbauer Ernst Kg | Polymerisierbare saeure und saeurederivate enthaltende verbindungen, dieselben enthaltende mischungen und ihre verwendung |
| US4814423A (en) * | 1987-11-06 | 1989-03-21 | Dentsply Research & Development Corp. | Dual bonding adhesive composition |
| US5055497A (en) * | 1988-03-17 | 1991-10-08 | Kuraray Company, Ltd. | Curable resinous composition |
| JPH0667816B2 (ja) * | 1988-11-11 | 1994-08-31 | 株式会社クラレ | 歯科用修復材 |
| JP2780722B2 (ja) * | 1989-10-02 | 1998-07-30 | 三井化学株式会社 | アクリル系共重合体、その製法およびその用途 |
| ATE88337T1 (de) * | 1989-10-19 | 1993-05-15 | Heraeus Kulzer Gmbh | Dentales haftmittel. |
| US5141560A (en) * | 1989-12-01 | 1992-08-25 | National Research Development Corporation | Dental cement |
| JP2634276B2 (ja) * | 1990-02-15 | 1997-07-23 | 株式会社松風 | プライマー組成物 |
| US5306338A (en) * | 1991-04-17 | 1994-04-26 | Sankin Kogyo K.K. | Dental restoration composition |
| US5367002A (en) * | 1992-02-06 | 1994-11-22 | Dentsply Research & Development Corp. | Dental composition and method |
| US5558517A (en) * | 1992-02-24 | 1996-09-24 | Clemson University | Polymeric prosthesis having a phosphonylated surface |
| US5227413A (en) * | 1992-02-27 | 1993-07-13 | Minnesota Mining And Manufacturing Company | Cements from β-dicarbonyl polymers |
| US5362769A (en) * | 1992-05-07 | 1994-11-08 | Ormco Corporation | Orthodontic adhesives |
| US5554669A (en) * | 1992-05-27 | 1996-09-10 | Mitsui Petrochemical Industries, Ltd. | Emulsion of polymer having (meth)acrylate unit and adhesive compositions containing the emulsion |
| US5338773A (en) * | 1993-04-19 | 1994-08-16 | Dentsply Research & Development Corp. | Dental composition and method |
-
1997
- 1997-02-19 US US08/803,602 patent/US6071528A/en not_active Expired - Fee Related
-
1998
- 1998-02-09 JP JP53669998A patent/JP2002514204A/ja not_active Ceased
- 1998-02-09 WO PCT/US1998/002503 patent/WO1998036639A1/en not_active Ceased
- 1998-02-09 AU AU63224/98A patent/AU6322498A/en not_active Abandoned
- 1998-02-09 EP EP98907410A patent/EP0981273A4/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012087070A (ja) * | 2010-10-15 | 2012-05-10 | Tokuyama Dental Corp | 重合性単量体 |
Also Published As
| Publication number | Publication date |
|---|---|
| US6071528A (en) | 2000-06-06 |
| AU6322498A (en) | 1998-09-09 |
| EP0981273A4 (en) | 2004-12-01 |
| EP0981273A1 (en) | 2000-03-01 |
| WO1998036639A1 (en) | 1998-08-27 |
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