JP2002508767A5 - - Google Patents

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Publication number
JP2002508767A5
JP2002508767A5 JP1999505154A JP50515499A JP2002508767A5 JP 2002508767 A5 JP2002508767 A5 JP 2002508767A5 JP 1999505154 A JP1999505154 A JP 1999505154A JP 50515499 A JP50515499 A JP 50515499A JP 2002508767 A5 JP2002508767 A5 JP 2002508767A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP1999505154A
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English (en)
Japanese (ja)
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JP4686696B2 (ja
JP2002508767A (ja
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Publication date
Priority claimed from AUPO7550A external-priority patent/AUPO755097A0/en
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Publication of JP2002508767A publication Critical patent/JP2002508767A/ja
Publication of JP2002508767A5 publication Critical patent/JP2002508767A5/ja
Application granted granted Critical
Publication of JP4686696B2 publication Critical patent/JP4686696B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP50515499A 1997-06-25 1998-06-25 C5a受容体およびGタンパク質結合受容体の環状アゴニストおよびアンタゴニスト Expired - Fee Related JP4686696B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU7550 1997-06-25
AUPO7550 1997-06-25
AUPO7550A AUPO755097A0 (en) 1997-06-25 1997-06-25 Receptor agonist and antagonist
PCT/AU1998/000490 WO1999000406A1 (en) 1997-06-25 1998-06-25 CYCLIC AGONISTS AND ANTAGONISTS OF C5a RECEPTORS AND G PROTEIN-COUPLED RECEPTORS

Publications (3)

Publication Number Publication Date
JP2002508767A JP2002508767A (ja) 2002-03-19
JP2002508767A5 true JP2002508767A5 (cg-RX-API-DMAC7.html) 2006-09-21
JP4686696B2 JP4686696B2 (ja) 2011-05-25

Family

ID=3801840

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50515499A Expired - Fee Related JP4686696B2 (ja) 1997-06-25 1998-06-25 C5a受容体およびGタンパク質結合受容体の環状アゴニストおよびアンタゴニスト

Country Status (11)

Country Link
US (5) US6821950B1 (cg-RX-API-DMAC7.html)
EP (1) EP1017713B1 (cg-RX-API-DMAC7.html)
JP (1) JP4686696B2 (cg-RX-API-DMAC7.html)
AT (1) ATE377606T1 (cg-RX-API-DMAC7.html)
AU (2) AUPO755097A0 (cg-RX-API-DMAC7.html)
CY (1) CY1107133T1 (cg-RX-API-DMAC7.html)
DE (1) DE69838678T2 (cg-RX-API-DMAC7.html)
DK (1) DK1017713T3 (cg-RX-API-DMAC7.html)
ES (1) ES2294816T3 (cg-RX-API-DMAC7.html)
PT (1) PT1017713E (cg-RX-API-DMAC7.html)
WO (1) WO1999000406A1 (cg-RX-API-DMAC7.html)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
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AUPO755097A0 (en) 1997-06-25 1997-07-17 University Of Queensland, The Receptor agonist and antagonist
AUPQ339899A0 (en) 1999-10-13 1999-11-04 University Of Queensland, The Novel molecules
ES2353077T3 (es) 2000-08-10 2011-02-25 Mitsubishi Tanabe Pharma Corporation Derivados de urea con sustitución en posición 3 y uso medicinal de los mismos.
CN1474803B (zh) 2000-09-14 2012-11-21 田边三菱制药株式会社 酰胺衍生物及其制备药物的用途
AUPR833401A0 (en) * 2001-10-17 2001-11-08 University Of Queensland, The G protein-coupled receptor antagonists
US8524862B2 (en) 2002-03-19 2013-09-03 Cincinnati Children's Hospital Medical Center Muteins of C5a anaphylatoxin and methods of inhibiting C5a
US20040014782A1 (en) * 2002-03-29 2004-01-22 Krause James E. Combination therapy for the treatment of diseases involving inflammatory components
AUPS160602A0 (en) * 2002-04-08 2002-05-16 University Of Queensland, The Therapeutic method
AU2002950657A0 (en) 2002-08-08 2002-09-12 Alchemia Limited Derivatives of monosaccharides for drug discovery
AU2002951995A0 (en) * 2002-10-11 2002-10-31 Alchemia Limited Classes of compounds that interact with gpcrs
AU2003266858B2 (en) * 2002-10-11 2006-09-14 Vast Bioscience Pty Limited Classes of compounds that interact with GPCRs
AU2002952086A0 (en) * 2002-10-16 2002-11-07 The University Of Queensland Treatment of osteoarthritis
WO2004035078A1 (en) * 2002-10-16 2004-04-29 The University Of Queensland Treatment of inflammatory bowel disease
AU2002952129A0 (en) * 2002-10-17 2002-10-31 The University Of Queensland Treatment of hypersensitivity conditions
AU2003902354A0 (en) * 2003-05-15 2003-05-29 Harkin, Denis W. Treatment of haemorrhagic shock
AU2003902586A0 (en) * 2003-05-26 2003-06-12 The University Of Queensland Treatment of burns
WO2005014849A2 (en) * 2003-07-03 2005-02-17 Euro-Celtique, S.A. Genes associated with responses to neuropathic pain
EP1498422A1 (de) * 2003-07-17 2005-01-19 Jerini AG C5a-Rezeptor-Antagonisten
CN101036057A (zh) * 2004-10-04 2007-09-12 阿尔卡米亚有限公司 选择性抑制剂
JP2008526915A (ja) * 2005-01-17 2008-07-24 イエリニ・アクチェンゲゼルシャフト C5a受容体アンタゴニスト
EP1861114B1 (en) * 2005-03-11 2011-02-02 Potentia Pharmaceuticals, Inc. Compositions comprising modulators of g-protein-coupled receptor for treatment of macular degeneration
EP1739078A1 (de) 2005-05-30 2007-01-03 Jerini AG C5a-Rezeptor-Antagonisten
US20070292421A1 (en) * 2005-07-28 2007-12-20 Feinberg Bruce B Method for treating preeclampsia
US8168584B2 (en) 2005-10-08 2012-05-01 Potentia Pharmaceuticals, Inc. Methods of treating age-related macular degeneration by compstatin and analogs thereof
PL2148691T3 (pl) 2007-02-05 2015-12-31 Apellis Pharmaceuticals Inc Analogi kompstatyny do stosowania w leczeniu stanów zapalnych układu oddechowego
US20110092446A1 (en) * 2007-07-20 2011-04-21 Cedric Francois Compositions and methods for treatment of trauma
EP2278987A4 (en) * 2008-03-28 2012-08-22 Apellis Ag MODULATION AND REPLY / IMPROVEMENT OF THE COMPLEMENTARY SYSTEM IN THE TREATMENT OF TRAUMATISM
JP2011526738A (ja) * 2008-07-02 2011-10-13 サンゴバン・パフォーマンス・プラスティックス・シェンヌー 枠付き装置、封止材およびその製造方法
BRPI0921237A2 (pt) 2008-11-10 2015-09-22 Alexion Pharma Inc métodos e composições para o tratamento de distúrbios associados ao complemento
EP2525814A4 (en) * 2010-01-22 2013-09-11 Univ Louisville Res Found METHODS OF TREATING OR PREVENTING PERIODONTITIS AND PARODONTIST-RELATED DISEASES
WO2011137395A1 (en) 2010-04-30 2011-11-03 Rother Russell P Anti-c5a antibodies and methods for using the antibodies
EP2588121A4 (en) * 2010-06-29 2013-12-04 Univ Nebraska C5A ANALOGUE AND USE METHOD THEREFOR
EP2468295A1 (en) 2010-12-21 2012-06-27 Affiris AG Vaccines based on peptides of the complement protein C5a
BR112013033272A2 (pt) 2011-06-22 2020-11-10 Apellis Pharmaceuticals, Inc. composição farmaceutica compreendendo um inibidor do complemento e um agente anti-th17, e usos dos mesmos
US9289467B2 (en) 2011-08-10 2016-03-22 Case Western Reserve University Compositions and methods for treating bone conditions
WO2014043223A1 (en) * 2012-09-11 2014-03-20 Hospital For Special Surgery Irhom2 inhibition for the treatment of complement mediated disorders
ES2879430T3 (es) 2012-11-15 2021-11-22 Apellis Pharmaceuticals Inc Análogos de compstatina de acción prolongada y composiciones y métodos relacionados
WO2014152391A1 (en) 2013-03-15 2014-09-25 Apellis Pharmaceuticals, Inc. Cell-penetrating compstatin analogs and uses thereof
AU2014248252A1 (en) * 2013-04-02 2015-10-29 M. Reza Ghadiri Uses of cyclic peptides for treating and preventing atherosclerosis
EP3290922A1 (en) 2013-08-07 2018-03-07 Alexion Pharmaceuticals, Inc. Atypical hemolytic uremic syndrome (ahus) biomarker proteins
FI3359555T3 (fi) 2015-10-07 2024-03-20 Apellis Pharmaceuticals Inc Annostusohjeet
MA45770A (fr) 2016-07-29 2019-06-05 Pfizer Peptides cycliques en tant qu'antagonistes du récepteur c5
JP7128182B2 (ja) 2016-10-27 2022-08-30 アレクシオン ファーマシューティカルズ, インコーポレイテッド 補体関連障害におけるC5b-9沈着に関するアッセイ
ES2893769T3 (es) 2017-04-03 2022-02-10 Inflarx Gmbh Tratamiento de enfermedades inflamatorias con inhibidores de la actividad de C5a
US10376595B2 (en) 2017-04-03 2019-08-13 Inflarx Gmbh Treatment of inflammatory diseases with inhibitors of C5a activity
JP2020516607A (ja) 2017-04-07 2020-06-11 アペリス・ファーマシューティカルズ・インコーポレイテッドApellis Pharmaceuticals,Inc. 投与レジメンならびに関連組成物および方法
EP3642230A1 (en) 2017-06-23 2020-04-29 InflaRx GmbH Treatment of inflammatory diseases with inhibitors of c5a activity
WO2019118938A1 (en) 2017-12-15 2019-06-20 Apellis Pharmaceuticals, Inc. Dosing regimens and related compositions and methods
WO2021067526A1 (en) 2019-10-02 2021-04-08 Alexion Pharmaceuticals, Inc. Complement inhibitors for treating drug-induced complement-mediated response
EP4126222A1 (en) 2020-03-27 2023-02-08 InflaRx GmbH Inhibitors of c5a for the treatment of corona virus infection
CN115667925A (zh) 2020-05-15 2023-01-31 阿雷克森制药公司 使用细胞外囊泡来检测补体激活的方法以及其用于评估和/或监测补体介导的疾病的治疗的用途
WO2024238421A1 (en) 2023-05-12 2024-11-21 Alexion Pharmaceuticals, Inc. Use of biomarkers for the identification and treatment of complement-mediated disorders
WO2024238422A1 (en) 2023-05-12 2024-11-21 Alexion Pharmaceuticals, Inc. Use of a panel of lectins for detection of complement biomarkers in urine extracellular vesicles
US12180274B2 (en) 2023-05-26 2024-12-31 Inflarx Gmbh Treatment of pneumonia and ARDS with inhibitors of C5a and IL-6 activity

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
US5386011A (en) 1990-12-27 1995-01-31 Abbott Laboratories Hexapeptide anaphylatoxin-receptor ligands
FI962319A7 (fi) * 1993-12-06 1996-06-03 Novartis Ag C5a-reseptorin antagonistit, joilla ei ole olennaista agonistiaktiivis uutta
US5807824A (en) * 1993-12-06 1998-09-15 Ciba-Geigy Corporation C5A receptor antagonists having substantially no agonist activity
US5614370A (en) * 1994-03-18 1997-03-25 Merck & Co., Inc. Assay to identify human C5a antagonists and agonists
US5696230A (en) * 1994-08-31 1997-12-09 The Board Of Regents Of The University Of Nebraska High-affinity response-selective C-terminal analogs of C5a anaphylatoxin
AUPO755097A0 (en) 1997-06-25 1997-07-17 University Of Queensland, The Receptor agonist and antagonist
AUPR833401A0 (en) 2001-10-17 2001-11-08 University Of Queensland, The G protein-coupled receptor antagonists
AUPS160602A0 (en) * 2002-04-08 2002-05-16 University Of Queensland, The Therapeutic method
AU2002952086A0 (en) * 2002-10-16 2002-11-07 The University Of Queensland Treatment of osteoarthritis

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