JP2002505888A - 唾液分析による新生物の検出 - Google Patents
唾液分析による新生物の検出Info
- Publication number
- JP2002505888A JP2002505888A JP2000535774A JP2000535774A JP2002505888A JP 2002505888 A JP2002505888 A JP 2002505888A JP 2000535774 A JP2000535774 A JP 2000535774A JP 2000535774 A JP2000535774 A JP 2000535774A JP 2002505888 A JP2002505888 A JP 2002505888A
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- nucleic acid
- target nucleic
- sequence
- dna
- oligonucleotide
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
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- C—CHEMISTRY; METALLURGY
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
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- C—CHEMISTRY; METALLURGY
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- A61B10/0051—Devices for taking samples of body liquids for taking saliva or sputum samples
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
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| PCT/US1999/005220 WO1999046408A1 (en) | 1998-03-10 | 1999-03-10 | Detection of neoplasia by analysis of saliva |
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| US7511131B2 (en) * | 2002-11-13 | 2009-03-31 | Genzyme Corporation | Antisense modulation of apolipoprotein B expression |
| US20060009410A1 (en) * | 2002-11-13 | 2006-01-12 | Crooke Rosanne M | Effects of apolipoprotein B inhibition on gene expression profiles in animals |
| JP5686493B2 (ja) | 2003-01-24 | 2015-03-18 | ユニバーシティ・オブ・ユタＵｎｉｖｅｒｓｉｔｙ Ｏｆ Ｕｔａｈ | テロメアの長さを決定することによって死亡の危険性を予測する方法 |
| CA2558649A1 (en) * | 2004-03-17 | 2005-09-29 | The Johns Hopkins University | Neoplasia diagnostic compositions and methods of use |
| US20050287558A1 (en) | 2004-05-05 | 2005-12-29 | Crooke Rosanne M | SNPs of apolipoprotein B and modulation of their expression |
| ES2663810T3 (es) * | 2004-08-10 | 2018-04-17 | Kastle Therapeutics, Llc | Métodos para modular los niveles de lipoproteínas y colesterol en humanos |
| EP2505646A1 (en) | 2006-05-05 | 2012-10-03 | Isis Pharmaceuticals, Inc. | Compounds and methods for modulating expression of CRP |
| US8088591B2 (en) * | 2006-05-12 | 2012-01-03 | University Of Miami | Biomarkers for detection and diagnosis of head and neck squamous cell carcinoma |
| KR20150090284A (ko) * | 2007-03-24 | 2015-08-05 | 젠자임 코포레이션 | 인간 아포리포프로틴 ｂ에 상보적인 안티센스 올리고뉴클레오타이드 투여 |
| US20090023138A1 (en) * | 2007-07-17 | 2009-01-22 | Zila Biotechnology, Inc. | Oral cancer markers and their detection |
| US8012678B2 (en) * | 2007-07-24 | 2011-09-06 | Wisconsin Alumni Research Foundation | Biomarkers for human papilloma virus-associated cancer |
| CA2748265C (en) | 2008-12-22 | 2018-04-03 | University Of Utah Research Foundation | Monochrome multiplex quantitative pcr |
| US9107933B2 (en) | 2009-03-16 | 2015-08-18 | Isis Pharmaceuticals, Inc. | Compositions and methods of targeting apolipoprotein B for the reduction of apolipoprotein C-III |
| ITBO20090554A1 (it) * | 2009-08-27 | 2011-02-28 | Maria Gabriella Fornaro | Metodo per individuare la predisposizione al carcinoma della prostata. |
| WO2011119934A2 (en) * | 2010-03-26 | 2011-09-29 | Mayo Foundation For Medical Education And Research | Methods and materials for detecting colorectal neoplasm |
| BR112014011563B1 (pt) | 2011-11-15 | 2022-05-24 | University Of Miami | Método para determinar um risco aumentado de carcinoma de células escamosas de cabeça e pescoço (hnscc) em um indivíduo humano infectado com papiloma vírus humano (hpv), e kit |
| CN104105798A (zh) * | 2011-12-31 | 2014-10-15 | 端粒健康公司 | 源自唾液的端粒丰度的量度和样本收集装置 |
| US9994911B2 (en) | 2013-03-14 | 2018-06-12 | Mayo Foundation For Medical Education And Research | Detecting neoplasm |
| ES2762860T3 (es) | 2013-05-22 | 2020-05-26 | Telomere Diagnostics Inc | Medidas de abundancia de telómeros cortos |
| US10301680B2 (en) | 2014-03-31 | 2019-05-28 | Mayo Foundation For Medical Education And Research | Detecting colorectal neoplasm |
| US10184154B2 (en) | 2014-09-26 | 2019-01-22 | Mayo Foundation For Medical Education And Research | Detecting cholangiocarcinoma |
| CA2971169A1 (en) | 2014-12-30 | 2016-07-07 | Telomere Diagnostics, Inc. | Multiplex quantitative pcr |
| US10030272B2 (en) | 2015-02-27 | 2018-07-24 | Mayo Foundation For Medical Education And Research | Detecting gastrointestinal neoplasms |
| US10435755B2 (en) | 2015-03-27 | 2019-10-08 | Exact Sciences Development Company, Llc | Detecting esophageal disorders |
| KR20250172724A (ko) | 2015-08-31 | 2025-12-09 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 위 신생물 검출 방법 |
| CA3020628A1 (en) | 2016-04-14 | 2017-10-19 | Mayo Foundation For Medical Education And Research | Detecting pancreatic high-grade dysplasia |
| US10370726B2 (en) | 2016-04-14 | 2019-08-06 | Mayo Foundation For Medical Education And Research | Detecting colorectal neoplasia |
| KR102747156B1 (ko) | 2017-02-28 | 2024-12-26 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 전립선 암의 검출 |
| US10975443B2 (en) | 2017-11-30 | 2021-04-13 | Mayo Foundation For Medical Education And Research | Detecting breast cancer |
| US12246067B2 (en) | 2018-06-19 | 2025-03-11 | Biontech Us Inc. | Neoantigens and uses thereof |
| CN114885938A (zh) * | 2022-02-25 | 2022-08-12 | 厦门迈威生物科技有限公司 | 一种浆膜腔积液脱落细胞保存液及其生产方法 |
| USD1034632S1 (en) * | 2022-05-03 | 2024-07-09 | SimpliSafe, Inc. | Display screen with graphical user interface |
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| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| DE69032864T3 (de) | 1989-03-29 | 2013-01-31 | The Johns Hopkins University | Nachweis des Ausfalls des Wildtyps des p53-Gens |
| US5527676A (en) | 1989-03-29 | 1996-06-18 | The Johns Hopkins University | Detection of loss of the wild-type P53 gene and kits therefor |
| AU8221191A (en) | 1990-06-27 | 1992-01-23 | Princeton University | Probes for detecting mutant p53 |
| AU662906B2 (en) | 1991-06-26 | 1995-09-21 | F. Hoffmann-La Roche Ag | Methods for detection of carcinoma metastases by nucleic acid amplification |
| DE69333289T2 (de) | 1992-04-01 | 2004-08-26 | The Johns Hopkins University School Of Medicine | Verfahren zur bestimmung von säugetier nukleinsäuren aus stuhlproben und dafür benötigte reagenzien |
| EP0655090B1 (en) | 1992-04-27 | 2000-12-27 | The Trustees Of Dartmouth College | Detection of gene sequences in biological fluids |
| US6235470B1 (en) | 1993-11-12 | 2001-05-22 | The Johns Hopkins University School Of Medicine | Detection of neoplasia by analysis of saliva |
| US5561041A (en) | 1993-11-12 | 1996-10-01 | The Johns Hopkins University School Of Medicine | Nucleic acid mutation detection by analysis of sputum |
| CH686982A5 (fr) * | 1993-12-16 | 1996-08-15 | Maurice Stroun | Méthode pour le diagnostic de cancers. |
| US5589579A (en) | 1994-07-19 | 1996-12-31 | Cytoclonal Pharmaceutics, Inc. | Gene sequence and probe for a marker of non-small cell lung carinoma |
| JPH10506527A (ja) * | 1994-08-31 | 1998-06-30 | ザ ジョーンズ ホプキンス ユニバーシティー スクール オブ メディシン | 組織中の高変異可能な核酸配列の検出 |
| EP0956365A4 (en) * | 1996-08-28 | 2004-08-25 | Univ Johns Hopkins Med | METHOD FOR DETECTING CELL PROLIFERATIVE DEREGULATIONS |
| DE19712332A1 (de) * | 1997-03-25 | 1998-10-01 | Boehringer Mannheim Gmbh | Verfahren zum Nachweis von Mikrosatelliten-Instabilität zur Tumordiagnostik |
| US6309827B1 (en) * | 1997-03-28 | 2001-10-30 | Orasure Technologies, Inc. | Simultaneous collection of DNA and non-nucleic analytes |
-
1998
- 1998-03-10 US US09/038,637 patent/US6235470B1/en not_active Expired - Lifetime
-
1999
- 1999-03-10 DE DE69940969T patent/DE69940969D1/de not_active Expired - Lifetime
- 1999-03-10 AT AT99911289T patent/ATE433498T1/de not_active IP Right Cessation
- 1999-03-10 EP EP99911289A patent/EP1062366B1/en not_active Expired - Lifetime
- 1999-03-10 AU AU29969/99A patent/AU769035B2/en not_active Expired
- 1999-03-10 CA CA002323060A patent/CA2323060A1/en not_active Abandoned
- 1999-03-10 WO PCT/US1999/005220 patent/WO1999046408A1/en not_active Ceased
- 1999-03-10 JP JP2000535774A patent/JP2002505888A/ja active Pending
-
2000
- 2000-09-08 NO NO20004504A patent/NO20004504L/no unknown
-
2001
- 2001-05-22 US US09/863,806 patent/US20020197608A1/en not_active Abandoned
-
2004
- 2004-01-05 JP JP2004000679A patent/JP2004159661A/ja active Pending
- 2004-01-09 US US10/754,478 patent/US7279312B2/en not_active Expired - Fee Related
-
2007
- 2007-10-08 US US11/868,683 patent/US7601521B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1062366B1 (en) | 2009-06-10 |
| HK1033765A1 (en) | 2001-09-21 |
| NO20004504L (no) | 2000-11-08 |
| US7279312B2 (en) | 2007-10-09 |
| EP1062366A4 (en) | 2002-05-08 |
| AU2996999A (en) | 1999-09-27 |
| WO1999046408A1 (en) | 1999-09-16 |
| DE69940969D1 (de) | 2009-07-23 |
| JP2004159661A (ja) | 2004-06-10 |
| US20050009040A1 (en) | 2005-01-13 |
| CA2323060A1 (en) | 1999-09-16 |
| AU769035B2 (en) | 2004-01-15 |
| US7601521B2 (en) | 2009-10-13 |
| AU2003266475A1 (en) | 2004-01-22 |
| US20020197608A1 (en) | 2002-12-26 |
| EP1062366A1 (en) | 2000-12-27 |
| ATE433498T1 (de) | 2009-06-15 |
| US20080124729A1 (en) | 2008-05-29 |
| NO20004504D0 (no) | 2000-09-08 |
| US6235470B1 (en) | 2001-05-22 |
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