AU769035B2 - Detection of neoplasia by analysis of saliva - Google Patents

Detection of neoplasia by analysis of saliva Download PDF

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Publication number
AU769035B2
AU769035B2 AU29969/99A AU2996999A AU769035B2 AU 769035 B2 AU769035 B2 AU 769035B2 AU 29969/99 A AU29969/99 A AU 29969/99A AU 2996999 A AU2996999 A AU 2996999A AU 769035 B2 AU769035 B2 AU 769035B2
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AU
Australia
Prior art keywords
seq
nucleic acid
linear
base pairs
length
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU29969/99A
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English (en)
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AU2996999A (en
Inventor
David Sidransky
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Johns Hopkins University
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Johns Hopkins University
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Filing date
Publication date
Application filed by Johns Hopkins University filed Critical Johns Hopkins University
Publication of AU2996999A publication Critical patent/AU2996999A/en
Priority to AU2003266475A priority Critical patent/AU2003266475B2/en
Application granted granted Critical
Publication of AU769035B2 publication Critical patent/AU769035B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B10/0051—Devices for taking samples of body liquids for taking saliva or sputum samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
AU29969/99A 1998-03-10 1999-03-10 Detection of neoplasia by analysis of saliva Expired AU769035B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003266475A AU2003266475B2 (en) 1998-03-10 2003-12-04 Detection of neoplasia by analysis of saliva

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/038637 1998-03-10
US09/038,637 US6235470B1 (en) 1993-11-12 1998-03-10 Detection of neoplasia by analysis of saliva
PCT/US1999/005220 WO1999046408A1 (en) 1998-03-10 1999-03-10 Detection of neoplasia by analysis of saliva

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2003266475A Division AU2003266475B2 (en) 1998-03-10 2003-12-04 Detection of neoplasia by analysis of saliva

Publications (2)

Publication Number Publication Date
AU2996999A AU2996999A (en) 1999-09-27
AU769035B2 true AU769035B2 (en) 2004-01-15

Family

ID=21901047

Family Applications (1)

Application Number Title Priority Date Filing Date
AU29969/99A Expired AU769035B2 (en) 1998-03-10 1999-03-10 Detection of neoplasia by analysis of saliva

Country Status (9)

Country Link
US (4) US6235470B1 (enExample)
EP (1) EP1062366B1 (enExample)
JP (2) JP2002505888A (enExample)
AT (1) ATE433498T1 (enExample)
AU (1) AU769035B2 (enExample)
CA (1) CA2323060A1 (enExample)
DE (1) DE69940969D1 (enExample)
NO (1) NO20004504L (enExample)
WO (1) WO1999046408A1 (enExample)

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US6235470B1 (en) * 1993-11-12 2001-05-22 The Johns Hopkins University School Of Medicine Detection of neoplasia by analysis of saliva
CA2410120A1 (en) * 1996-08-28 1998-03-05 The Johns Hopkins University School Of Medicine Method for detecting cell proliferative disorders
US7888324B2 (en) * 2001-08-01 2011-02-15 Genzyme Corporation Antisense modulation of apolipoprotein B expression
US7407943B2 (en) * 2001-08-01 2008-08-05 Isis Pharmaceuticals, Inc. Antisense modulation of apolipoprotein B expression
CA2457907A1 (en) * 2001-12-14 2003-09-04 Zila, Inc. Stain-directed molecular analysis for cancer prognosis and diagnosis
US7511131B2 (en) * 2002-11-13 2009-03-31 Genzyme Corporation Antisense modulation of apolipoprotein B expression
US20060009410A1 (en) * 2002-11-13 2006-01-12 Crooke Rosanne M Effects of apolipoprotein B inhibition on gene expression profiles in animals
WO2004068110A2 (en) 2003-01-24 2004-08-12 University Of Utah Methods of predicting mortality risk by determining telomere length
US20090023134A1 (en) * 2004-03-17 2009-01-22 The Johns Hopkins University Neoplasia diagnostic compositions and methods of use
US20050287558A1 (en) 2004-05-05 2005-12-29 Crooke Rosanne M SNPs of apolipoprotein B and modulation of their expression
SI2409713T1 (sl) * 2004-08-10 2015-10-30 Genzyme Corporation Oligonukleotidi za uporabo pri uravnavanju nivojev lipoproteinov in holesterola pri ljudeh
EP2505646A1 (en) 2006-05-05 2012-10-03 Isis Pharmaceuticals, Inc. Compounds and methods for modulating expression of CRP
EP2032716A4 (en) * 2006-05-12 2010-03-17 Univ Miami BIOMARKERS FOR THE DETECTION AND DIAGNOSIS OF PANELEPITHELIN CARCINOMAS IN THE HEAD AND NECK
US9347061B2 (en) * 2007-03-24 2016-05-24 Genzyme Corporation Administering antisense oligonucleotides complementary to human apolipoprotein B
US20090023138A1 (en) * 2007-07-17 2009-01-22 Zila Biotechnology, Inc. Oral cancer markers and their detection
US8012678B2 (en) 2007-07-24 2011-09-06 Wisconsin Alumni Research Foundation Biomarkers for human papilloma virus-associated cancer
ES2433718T3 (es) 2008-12-22 2013-12-12 University Of Utah Research Foundation PCR multiplex monocromática cuantitativa
EP2408796B1 (en) 2009-03-16 2020-04-22 Ionis Pharmaceuticals, Inc. Targeting Apolipoprotein B for the reduction of Apolipoprotein C-III
ITBO20090554A1 (it) * 2009-08-27 2011-02-28 Maria Gabriella Fornaro Metodo per individuare la predisposizione al carcinoma della prostata.
EP2553463B1 (en) * 2010-03-26 2017-05-03 Hongzhi Zou Methods and materials for detecting colorectal neoplasm
AU2012340441A1 (en) 2011-11-15 2014-05-29 University Of Miami Methods for detecting human papillomavirus and providing prognosis for head and neck squamous cell carcinoma
TW201343919A (zh) * 2011-12-31 2013-11-01 Telome Health Inc 唾液衍生之端粒豐度計量及樣本收集裝置
EP2971179B1 (en) 2013-03-14 2019-01-09 Mayo Foundation for Medical Education and Research Detecting neoplasm
JP6546158B2 (ja) 2013-05-22 2019-07-17 テロメア ダイアグノスティクス インコーポレイテッド 短いテロメアの存在量の測定
US10301680B2 (en) 2014-03-31 2019-05-28 Mayo Foundation For Medical Education And Research Detecting colorectal neoplasm
US10184154B2 (en) 2014-09-26 2019-01-22 Mayo Foundation For Medical Education And Research Detecting cholangiocarcinoma
WO2016108954A1 (en) 2014-12-30 2016-07-07 Telomere Diagnostics, Inc. Multiplex quantitative pcr
US10030272B2 (en) 2015-02-27 2018-07-24 Mayo Foundation For Medical Education And Research Detecting gastrointestinal neoplasms
WO2016160454A1 (en) 2015-03-27 2016-10-06 Exact Sciences Corporation Detecting esophageal disorders
JP6871926B2 (ja) 2015-08-31 2021-05-19 マヨ ファウンデーション フォア メディカル エデュケーション アンド リサーチＭａｙｏ Ｆｏｕｎｄａｔｉｏｎ ｆｏｒ Ｍｅｄｉｃａｌ Ｅｄｕｃａｔｉｏｎ ａｎｄ Ｒｅｓｅａｒｃｈ 胃の新生物を検出すること
CN109153993B (zh) 2016-04-14 2023-02-17 梅约医学教育与研究基金会 检测胰腺高度异型增生
US10370726B2 (en) 2016-04-14 2019-08-06 Mayo Foundation For Medical Education And Research Detecting colorectal neoplasia
US10934592B2 (en) 2017-02-28 2021-03-02 Mayo Foundation For Medical Education And Research Detecting prostate cancer
AU2018374176B2 (en) 2017-11-30 2024-12-12 Exact Sciences Corporation Detecting breast cancer
SG11202012653XA (en) 2018-06-19 2021-01-28 Biontech Us Inc Neoantigens and uses thereof
CN114885938A (zh) * 2022-02-25 2022-08-12 厦门迈威生物科技有限公司 一种浆膜腔积液脱落细胞保存液及其生产方法
USD1034632S1 (en) * 2022-05-03 2024-07-09 SimpliSafe, Inc. Display screen with graphical user interface

Citations (3)

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Publication number Priority date Publication date Assignee Title
WO1996006951A1 (en) * 1994-08-31 1996-03-07 The Johns Hopkins University School Of Medicine Detection of hypermutable nucleic acid sequence in tissue
US5561041A (en) * 1993-11-12 1996-10-01 The Johns Hopkins University School Of Medicine Nucleic acid mutation detection by analysis of sputum
WO1998008980A1 (en) * 1996-08-28 1998-03-05 The Johns Hopkins University School Of Medicine Method for detecting cell proliferative disorders

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US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
EP0390323B2 (en) 1989-03-29 2012-08-08 Johns Hopkins University Detection of loss of the wild-type p53 gene
US5527676A (en) 1989-03-29 1996-06-18 The Johns Hopkins University Detection of loss of the wild-type P53 gene and kits therefor
DE69133528T2 (de) 1990-06-27 2006-09-07 Princeton University Proteinkomplex p53/p90
AU662906B2 (en) 1991-06-26 1995-09-21 F. Hoffmann-La Roche Ag Methods for detection of carcinoma metastases by nucleic acid amplification
JP3633932B2 (ja) 1992-04-01 2005-03-30 ザ ジョーンズ ホプキンズ ユニバーシティー スクール オブ メディシン 糞便試料から単離した哺乳類の核酸を検出する方法、およびその検出用試薬
CA2134552A1 (en) 1992-04-27 1993-11-11 George D. Sorenson Detection of gene sequences in biological fluids
US6235470B1 (en) * 1993-11-12 2001-05-22 The Johns Hopkins University School Of Medicine Detection of neoplasia by analysis of saliva
CH686982A5 (fr) * 1993-12-16 1996-08-15 Maurice Stroun Méthode pour le diagnostic de cancers.
US5589579A (en) 1994-07-19 1996-12-31 Cytoclonal Pharmaceutics, Inc. Gene sequence and probe for a marker of non-small cell lung carinoma
DE19712332A1 (de) * 1997-03-25 1998-10-01 Boehringer Mannheim Gmbh Verfahren zum Nachweis von Mikrosatelliten-Instabilität zur Tumordiagnostik
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Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
US5561041A (en) * 1993-11-12 1996-10-01 The Johns Hopkins University School Of Medicine Nucleic acid mutation detection by analysis of sputum
WO1996006951A1 (en) * 1994-08-31 1996-03-07 The Johns Hopkins University School Of Medicine Detection of hypermutable nucleic acid sequence in tissue
WO1998008980A1 (en) * 1996-08-28 1998-03-05 The Johns Hopkins University School Of Medicine Method for detecting cell proliferative disorders

Also Published As

Publication number Publication date
US6235470B1 (en) 2001-05-22
AU2003266475A1 (en) 2004-01-22
JP2004159661A (ja) 2004-06-10
EP1062366B1 (en) 2009-06-10
NO20004504D0 (no) 2000-09-08
HK1033765A1 (en) 2001-09-21
AU2996999A (en) 1999-09-27
US20080124729A1 (en) 2008-05-29
US20050009040A1 (en) 2005-01-13
JP2002505888A (ja) 2002-02-26
EP1062366A4 (en) 2002-05-08
US20020197608A1 (en) 2002-12-26
ATE433498T1 (de) 2009-06-15
CA2323060A1 (en) 1999-09-16
US7279312B2 (en) 2007-10-09
US7601521B2 (en) 2009-10-13
EP1062366A1 (en) 2000-12-27
DE69940969D1 (de) 2009-07-23
NO20004504L (no) 2000-11-08
WO1999046408A1 (en) 1999-09-16

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired