JP2002505309A - 腫瘍治療のための組成物および方法 - Google Patents
腫瘍治療のための組成物および方法Info
- Publication number
- JP2002505309A JP2002505309A JP2000534245A JP2000534245A JP2002505309A JP 2002505309 A JP2002505309 A JP 2002505309A JP 2000534245 A JP2000534245 A JP 2000534245A JP 2000534245 A JP2000534245 A JP 2000534245A JP 2002505309 A JP2002505309 A JP 2002505309A
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- egfr
- cells
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- erbb
- tumor
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- A61K2039/507—Comprising a combination of two or more separate antibodies
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- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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Applications Claiming Priority (5)
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| US7678898P | 1998-03-04 | 1998-03-04 | |
| US60/076,788 | 1998-03-04 | ||
| US09/111,681 US6417168B1 (en) | 1998-03-04 | 1998-07-08 | Compositions and methods of treating tumors |
| US09/111,681 | 1998-07-08 | ||
| PCT/US1999/004777 WO1999044645A1 (en) | 1998-03-04 | 1999-03-04 | Compositions and methods of treating tumors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| JP2011224347A Division JP5719270B2 (ja) | 1998-03-04 | 2011-10-11 | 腫瘍治療のための組成物および方法 |
Publications (2)
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| JP2002505309A true JP2002505309A (ja) | 2002-02-19 |
| JP2002505309A5 JP2002505309A5 (cg-RX-API-DMAC7.html) | 2012-06-14 |
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| JP2000534245A Pending JP2002505309A (ja) | 1998-03-04 | 1999-03-04 | 腫瘍治療のための組成物および方法 |
| JP2011224347A Expired - Lifetime JP5719270B2 (ja) | 1998-03-04 | 2011-10-11 | 腫瘍治療のための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
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| JP2011224347A Expired - Lifetime JP5719270B2 (ja) | 1998-03-04 | 2011-10-11 | 腫瘍治療のための組成物および方法 |
Country Status (13)
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| US (8) | US6417168B1 (cg-RX-API-DMAC7.html) |
| EP (2) | EP1058562B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2002505309A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE334702T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU757237C (cg-RX-API-DMAC7.html) |
| CA (1) | CA2322592A1 (cg-RX-API-DMAC7.html) |
| CY (1) | CY1105475T1 (cg-RX-API-DMAC7.html) |
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| HK (1) | HK1225997A1 (cg-RX-API-DMAC7.html) |
| PT (1) | PT1058562E (cg-RX-API-DMAC7.html) |
| WO (1) | WO1999044645A1 (cg-RX-API-DMAC7.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017522047A (ja) * | 2014-06-27 | 2017-08-10 | アンジオクライン・バイオサイエンス・インコーポレイテッドＡｎｇｉｏｃｒｉｎｅ Ｂｉｏｓｃｉｅｎｃｅ， Ｉｎｃ． | アデノウイルスｅ４ｑｒｆ１を発現する神経系細胞、並びに、その製造および使用方法 |
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| US20030108545A1 (en) * | 1994-02-10 | 2003-06-12 | Patricia Rockwell | Combination methods of inhibiting tumor growth with a vascular endothelial growth factor receptor antagonist |
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| IL122614A0 (en) | 1995-06-15 | 1998-08-16 | Introgene Bv | Packaging systems for human recombinant adenovirus to be used in gene therapy |
| EP1745799B1 (en) | 1998-03-04 | 2015-09-02 | The Trustees of The University of Pennsylvania | Compositions and methods of treating tumors |
| US6417168B1 (en) | 1998-03-04 | 2002-07-09 | The Trustees Of The University Of Pennsylvania | Compositions and methods of treating tumors |
| US20030224001A1 (en) * | 1998-03-19 | 2003-12-04 | Goldstein Neil I. | Antibody and antibody fragments for inhibiting the growth of tumors |
| ZA200007412B (en) * | 1998-05-15 | 2002-03-12 | Imclone Systems Inc | Treatment of human tumors with radiation and inhibitors of growth factor receptor tyrosine kinases. |
| US6929946B1 (en) * | 1998-11-20 | 2005-08-16 | Crucell Holland B.V. | Gene delivery vectors provided with a tissue tropism for smooth muscle cells, and/or endothelial cells |
| US7396810B1 (en) * | 2000-08-14 | 2008-07-08 | Oregon Health Sciences University | Compositions and methods for treating cancer by modulating HER-2 and EGF receptors |
| US7393823B1 (en) | 1999-01-20 | 2008-07-01 | Oregon Health And Science University | HER-2 binding antagonists |
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| PL365999A1 (en) * | 1999-05-14 | 2005-01-24 | Imclone Systems Incorporated | Treatment of refractory human tumors with epidermal growth factor receptor antagonists |
| US6913922B1 (en) * | 1999-05-18 | 2005-07-05 | Crucell Holland B.V. | Serotype of adenovirus and uses thereof |
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| AU757237B2 (en) | 2003-02-06 |
| PT1058562E (pt) | 2006-11-30 |
| US20130204069A1 (en) | 2013-08-08 |
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