JP2002504503A5 - - Google Patents

Download PDF

Info

Publication number
JP2002504503A5
JP2002504503A5 JP2000533087A JP2000533087A JP2002504503A5 JP 2002504503 A5 JP2002504503 A5 JP 2002504503A5 JP 2000533087 A JP2000533087 A JP 2000533087A JP 2000533087 A JP2000533087 A JP 2000533087A JP 2002504503 A5 JP2002504503 A5 JP 2002504503A5
Authority
JP
Japan
Prior art keywords
medical composition
cells
stromal cells
disease
isolated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000533087A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002504503A (ja
JP4748855B2 (ja
Filing date
Publication date
Priority claimed from US09/028,395 external-priority patent/US6653134B2/en
Application filed filed Critical
Publication of JP2002504503A publication Critical patent/JP2002504503A/ja
Publication of JP2002504503A5 publication Critical patent/JP2002504503A5/ja
Application granted granted Critical
Publication of JP4748855B2 publication Critical patent/JP4748855B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2000533087A 1998-02-24 1999-02-24 中枢神経系の疾病の処置における使用のための単離されたストロマ細胞 Expired - Fee Related JP4748855B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/028,395 US6653134B2 (en) 1995-03-28 1998-02-24 Isolated stromal cells for use in the treatment of diseases of the central nervous system
US09/028,395 1998-02-24
PCT/US1999/003897 WO1999043286A2 (en) 1998-02-24 1999-02-24 Isolated stromal cells for use in the treatment of diseases of the central nervous system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010075872A Division JP2010209074A (ja) 1998-02-24 2010-03-29 中枢神経系の疾病の処置における使用のための単離されたストロマ細胞

Publications (3)

Publication Number Publication Date
JP2002504503A JP2002504503A (ja) 2002-02-12
JP2002504503A5 true JP2002504503A5 (https=) 2006-04-20
JP4748855B2 JP4748855B2 (ja) 2011-08-17

Family

ID=21843237

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000533087A Expired - Fee Related JP4748855B2 (ja) 1998-02-24 1999-02-24 中枢神経系の疾病の処置における使用のための単離されたストロマ細胞
JP2010075872A Pending JP2010209074A (ja) 1998-02-24 2010-03-29 中枢神経系の疾病の処置における使用のための単離されたストロマ細胞

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010075872A Pending JP2010209074A (ja) 1998-02-24 2010-03-29 中枢神経系の疾病の処置における使用のための単離されたストロマ細胞

Country Status (10)

Country Link
US (3) US6653134B2 (https=)
EP (2) EP1815862A1 (https=)
JP (2) JP4748855B2 (https=)
AT (1) ATE394110T1 (https=)
AU (1) AU2782499A (https=)
CA (1) CA2321883A1 (https=)
DE (1) DE69938653D1 (https=)
ES (1) ES2307332T3 (https=)
PT (1) PT1059929E (https=)
WO (1) WO1999043286A2 (https=)

Families Citing this family (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6653134B2 (en) * 1995-03-28 2003-11-25 Cp Hahnemann University Isolated stromal cells for use in the treatment of diseases of the central nervous system
US7022321B2 (en) 1997-04-10 2006-04-04 Eglitis Martin A Use of marrow-derived glial progenitor cells as gene delivery vehicles into the central nervous system
WO1999056759A1 (en) * 1998-05-07 1999-11-11 University Of South Florida Bone marrow cells as a source of neurons for brain and spinal cord repair
US7001746B1 (en) 1999-01-29 2006-02-21 Artecel Sciences, Inc. Methods and compositions for the differentiation of human preadipocytes into adipocytes
US20030082152A1 (en) 1999-03-10 2003-05-01 Hedrick Marc H. Adipose-derived stem cells and lattices
JP2002544234A (ja) * 1999-05-14 2002-12-24 ヘンリー フォード ヘルス システム 発作の処置のための骨髄移植
US8017112B2 (en) 1999-05-14 2011-09-13 Henry Ford Health System Transplantation of bone marrow stromal cells for treatment of neurodegenerative diseases
US7838289B2 (en) * 2001-02-14 2010-11-23 Abt Holding Company Assay utilizing multipotent adult stem cells
US7927587B2 (en) * 1999-08-05 2011-04-19 Regents Of The University Of Minnesota MAPC administration for the treatment of lysosomal storage disorders
US7015037B1 (en) 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
US8609412B2 (en) * 1999-08-05 2013-12-17 Regents Of The University Of Minnesota Mapc generation of lung tissue
EP2348104A1 (en) * 1999-08-05 2011-07-27 Mcl Llc Multipotent adult stem cells and methods for isolation
US10638734B2 (en) 2004-01-05 2020-05-05 Abt Holding Company Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
US8075881B2 (en) * 1999-08-05 2011-12-13 Regents Of The University Of Minnesota Use of multipotent adult stem cells in treatment of myocardial infarction and congestive heart failure
US8252280B1 (en) 1999-08-05 2012-08-28 Regents Of The University Of Minnesota MAPC generation of muscle
US6555374B1 (en) 1999-08-19 2003-04-29 Artecel Sciences, Inc. Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof
ES2292564T3 (es) 2000-02-11 2008-03-16 Philadelphia Health And Education Corporation Diferenciacion de celulas de la medula osea en celulas neuronales y usos asociados.
ES2300320T3 (es) 2000-02-26 2008-06-16 Artecel, Inc. Celulas madre pluripotentes generadas a partir de celulas del estroma derivadas de tejido adiposo y sus usos.
US7582292B2 (en) * 2000-02-26 2009-09-01 Artecel, Inc. Adipose tissue derived stromal cells for the treatment of neurological disorders
EP1263930A4 (en) * 2000-03-09 2004-07-21 Saneron Ccel Therapeutics Inc HUMAN CORD BLOOD BLOOD AS A SOURCE FOR NEURAL TISSUE FOR HEALING THE BRAIN AND BACK MARK
WO2001078753A2 (en) * 2000-04-12 2001-10-25 Children's Hospital Of Philadelphia Therapeutic uses for mesenchymal stromal cells
US6673606B1 (en) 2000-04-12 2004-01-06 The Children's Hospital Of Philadelphia Therapeutic uses for mesenchymal stromal cells
CA2413910A1 (en) * 2000-06-26 2002-12-27 Renomedix Institute Inc. Cell fractions containing cells capable of differentating into neural cells
WO2002034889A2 (en) * 2000-10-24 2002-05-02 Children's Hospital Of Philadelphia Therapeutic uses for mesenchymal stromal cells
US20030003090A1 (en) 2001-05-31 2003-01-02 Prockop Darwin J. Directed in vitro differentiation of marrow stromal cells into neural cell progenitors
DE10144326B4 (de) * 2001-09-10 2005-09-22 Siemens Ag Verfahren und System zur Überwachung eines Reifenluftdrucks
US9969980B2 (en) * 2001-09-21 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
US7771716B2 (en) 2001-12-07 2010-08-10 Cytori Therapeutics, Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
US20050048035A1 (en) 2001-12-07 2005-03-03 Fraser John K. Methods of using regenerative cells in the treatment of stroke and related diseases and disorders
US9597395B2 (en) 2001-12-07 2017-03-21 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
US20050095228A1 (en) 2001-12-07 2005-05-05 Fraser John K. Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders
EP1471970A4 (en) 2002-01-14 2006-08-02 Univ Illinois NOVEL MULTIPOTENT STEM CELLS OF MAMMALIAN ORIGIN, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION OF SAID CELLS
US20060104962A1 (en) * 2002-07-25 2006-05-18 The Scripps Research Institute Transfected hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith
US9969977B2 (en) * 2002-09-20 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
CN100572535C (zh) 2002-10-22 2009-12-23 卫材R&D管理有限公司 在分裂停止后的产多巴胺型神经元前体细胞中特异性表达的基因
US20060228798A1 (en) 2002-11-27 2006-10-12 Catherine Verfaillie Homologous recombination in multipotent adult progenitor cells
US7485460B2 (en) 2003-05-21 2009-02-03 Tulane University Health Sciences Center Enhanced growth of adult stem cells with Dkk-1
US8426200B2 (en) * 2003-07-02 2013-04-23 Regents Of The University Of Minnesota Neuronal differentiation of stem cells
US20050002904A1 (en) * 2003-07-03 2005-01-06 Wary Kishore K. Uses of vascular endothelial growth factor and type I collagen inducible protein (VCIP)
AU2004296848A1 (en) 2003-12-04 2005-06-23 Regents Of The University Of Minnesota Compositions and methods for the treatment of lysosomal storage disorders
EP2298864B1 (en) * 2004-03-22 2017-10-11 Mesoblast International Sàrl Mesenchymal stem cells and uses therefor
EP1737950B9 (en) 2004-04-12 2012-04-18 Sanbio, Inc. Cells exhibiting neuronal progenitor cell characteristics
CA2574177C (en) 2004-07-22 2019-01-08 Eisai Co., Ltd. Lrp4/corin dopaminergic neuron progenitor cell markers
WO2006046583A1 (ja) * 2004-10-26 2006-05-04 Santen Pharmaceutical Co., Ltd. 視細胞またはその機能を再生させるための材料
US20090010873A1 (en) * 2004-11-29 2009-01-08 Yeda Research And Development Co. Ltd. Methods of Cell Therapy, Neurogenesis and Oligodendrogenesis
EP2428563A1 (en) * 2005-02-10 2012-03-14 Regents Of The University Of Minnesota Vascular/lymphatic endothelial cells
CN101218341A (zh) * 2005-05-05 2008-07-09 明尼苏达大学董事会 Nk细胞抑制作用用于促进定植的mhc-i阴性细胞持续存在的用途
WO2006121454A2 (en) * 2005-05-05 2006-11-16 Regents Of The University Of Minnesota Use of mapc or progeny therefrom to populate lymphohematopoietic tissues
JP2006345726A (ja) * 2005-06-14 2006-12-28 Hamamatsu Univ School Of Medicine 脳腫瘍治療用発現ベクター
EP1893747B1 (en) * 2005-06-16 2014-09-03 Ramot at Tel Aviv University Ltd. Isolated cells and populations comprising same for the treatment of cns diseases
WO2007117262A2 (en) * 2005-07-29 2007-10-18 Athersys, Inc. Culture of non-embryonic cells at high cell density
EP1950292A4 (en) 2005-08-18 2009-01-21 Eisai R&D Man Co Ltd Nato3, DOPAMINE PRODUCER NEURONE GROWTH PROGENITOR CELL MARKER
KR101022401B1 (ko) * 2005-09-29 2011-03-15 아주대학교산학협력단 자살유전자를 발현하는 중간엽 줄기세포를 포함하는 암치료용 조성물
CN101310012B (zh) * 2005-10-14 2012-05-09 明尼苏达大学董事会 非胚胎干细胞分化成具有胰腺表型的细胞
US20080286249A1 (en) * 2006-01-12 2008-11-20 Varney Timothy R Use of mesenchymal stem cells for treating genetic diseases and disorders
GB0600972D0 (en) * 2006-01-18 2006-03-01 Univ Leeds Enrichment of cells
US20080038237A1 (en) * 2006-02-28 2008-02-14 Sapolsky Robert M Trojan horse immunotherapy
CA2649250A1 (en) 2006-04-11 2007-10-25 Eisai R & D Management Co., Ltd. Dopaminergic neuron progenitor cell marker 187a5
JP2009535347A (ja) * 2006-04-28 2009-10-01 テュレーン・ユニバーシティ・ヘルス・サイエンシーズ・センター 糖尿病の治療方法
NZ582616A (en) * 2007-06-15 2012-07-27 Garnet Biotherapeutics Inc Treatment of diseases and disorders using self-renewing colony forming cells cultured and expanded in vitro
EP2245141B1 (en) * 2008-01-18 2018-03-14 Regents of the University of Minnesota Stem cell aggregates and methods for making and using
WO2009129497A2 (en) * 2008-04-18 2009-10-22 Arizona Board Of Regents, A Body Corp. Of The State Of Arizona, Acting For And On Behalf Of The University Of Arizona Methods and compositions for treating and identifying compounds to treat age-related macular degeneration
EP2620493B1 (en) 2008-05-28 2019-03-27 Ramot at Tel Aviv University Ltd. Mesenchymal stem cells for the treatment of CNS diseases
WO2010021993A1 (en) 2008-08-19 2010-02-25 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease
US9057051B2 (en) 2008-10-31 2015-06-16 Katholieke Universiteit Leuven Optimized methods for differentiation of cells into cells with hepatocyte progenitor phenotypes, cells produced by the methods, and methods of using the cells
SG178064A1 (en) * 2009-07-21 2012-03-29 Abt Holding Co Use of stem cells to reduce leukocyte extravasation
EP2456860B1 (en) * 2009-07-21 2018-09-05 ABT Holding Company Use of stem cells to reduce leukocyte extravasation
US20110206647A1 (en) * 2010-02-25 2011-08-25 Abt Holding Company Modulation of Angiogenesis
WO2011106476A1 (en) * 2010-02-25 2011-09-01 Abt Holding Company Modulation of microglia activation
WO2011143415A1 (en) 2010-05-12 2011-11-17 Abt Holding Company Modulation of splenocytes in cell therapy
US9090878B2 (en) 2010-06-17 2015-07-28 Katholieke Universiteit Leuven Methods for differentiating cells into hepatic stellate cells and hepatic sinusoidal endothelial cells, cells produced by the methods, and methods for using the cells
EP2609191B1 (en) 2010-08-24 2017-11-22 Regents Of The University Of Minnesota Non-static suspension culture of cell aggregates
US20120087933A1 (en) 2010-10-08 2012-04-12 Samson Tom Enhanced msc preparations
EP2625264B1 (en) 2010-10-08 2022-12-07 Terumo BCT, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
WO2012156968A2 (en) 2011-05-19 2012-11-22 Ariel - University Research And Development Company, Ltd. Use of mesenchymal stem cells for the improvement of affective and cognitive function
JP6090937B2 (ja) 2011-07-27 2017-03-08 国立大学法人京都大学 新規ドーパミン産生神経前駆細胞マーカー
JP6156889B2 (ja) 2013-02-06 2017-07-05 Ｎｃメディカルリサーチ株式会社 神経変性の治療のための不均質な骨髄細胞の亜集団を調製する方法
JP6666240B2 (ja) 2013-04-12 2020-03-13 フランチェスカ， サベリオ ラ 移植のための臓器の改良
JP6633522B2 (ja) 2013-11-16 2020-01-22 テルモ ビーシーティー、インコーポレーテッド バイオリアクターにおける細胞増殖
WO2015148704A1 (en) 2014-03-25 2015-10-01 Terumo Bct, Inc. Passive replacement of media
CN104161771A (zh) * 2014-04-09 2014-11-26 大连医科大学 骨髓间充质干细胞来源的神经细胞作为治疗正己烷致周围性神经病的药物的应用
US20160090569A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled Feed
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
KR20180102661A (ko) 2016-01-21 2018-09-17 에이비티 홀딩 컴퍼니 상처 치유를 위한 줄기 세포
JP7034949B2 (ja) 2016-05-25 2022-03-14 テルモ ビーシーティー、インコーポレーテッド 細胞の増殖
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
CN117247899A (zh) 2017-03-31 2023-12-19 泰尔茂比司特公司 细胞扩增
US11464804B1 (en) 2017-11-15 2022-10-11 Enrico Stazzone Intrathecal multifactorial infusion of heterogeneous autologous cell therapy
CN119033819A (zh) 2017-11-22 2024-11-29 迈索布拉斯特国际有限公司 细胞组合物及治疗方法
GB2619893A (en) 2021-03-23 2023-12-20 Terumo Bct Inc Cell capture and expansion
US12152699B2 (en) 2022-02-28 2024-11-26 Terumo Bct, Inc. Multiple-tube pinch valve assembly
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4391909A (en) 1979-03-28 1983-07-05 Damon Corporation Microcapsules containing viable tissue cells
JPS6030654B2 (ja) * 1980-12-31 1985-07-17 株式会社林原生物化学研究所 ヒトコロニ−刺激因子の製造方法
US4806355A (en) 1983-06-06 1989-02-21 Connaught Laboratories Limited Microencapsulation of living tissue and cells
US4609551A (en) * 1984-03-20 1986-09-02 Arnold Caplan Process of and material for stimulating growth of cartilage and bony tissue at anatomical sites
US4608199A (en) * 1984-03-20 1986-08-26 Arnold Caplan Bone protein purification process
US4620327A (en) * 1984-07-05 1986-11-04 Caplan Arnold I Process of adapting soluble bone protein for use in stimulating osteoinduction
US4666828A (en) * 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4801531A (en) * 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US4678470A (en) * 1985-05-29 1987-07-07 American Hospital Supply Corporation Bone-grafting material
US4902295A (en) 1985-08-26 1990-02-20 Hana Biologics, Inc. Transplantable artificial tissue
US4997443A (en) 1985-08-26 1991-03-05 Hana Biologics, Inc. Transplantable artificial tissue and process
US4942129A (en) 1987-07-28 1990-07-17 Queen's University At Kingston Multiple membrane microencapsulation
US5283187A (en) * 1987-11-17 1994-02-01 Brown University Research Foundation Cell culture-containing tubular capsule produced by co-extrusion
US4904259A (en) 1988-04-29 1990-02-27 Samuel Itay Compositions and methods for repair of cartilage and bone
US5272057A (en) * 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5082670A (en) 1988-12-15 1992-01-21 The Regents Of The University Of California Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system
DE69012601T2 (de) 1989-02-02 1995-01-19 Joel S Greenberger Gentherapie durch stützgewebebezügliche Zellen.
US5192659A (en) * 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
US5612211A (en) * 1990-06-08 1997-03-18 New York University Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors
US5344454A (en) 1991-07-24 1994-09-06 Baxter International Inc. Closed porous chambers for implanting tissue in a host
US5314471A (en) 1991-07-24 1994-05-24 Baxter International Inc. Tissue inplant systems and methods for sustaining viable high cell densities within a host
US5197985A (en) * 1990-11-16 1993-03-30 Caplan Arnold I Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5226914A (en) * 1990-11-16 1993-07-13 Caplan Arnold I Method for treating connective tissue disorders
US5851832A (en) * 1991-07-08 1998-12-22 Neurospheres, Ltd. In vitro growth and proliferation of multipotent neural stem cells and their progeny
US5750376A (en) * 1991-07-08 1998-05-12 Neurospheres Holdings Ltd. In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
US5334640A (en) 1992-04-08 1994-08-02 Clover Consolidated, Ltd. Ionically covalently crosslinked and crosslinkable biocompatible encapsulation compositions and methods
JPH08509215A (ja) * 1993-04-13 1996-10-01 アメリカ合衆国 移植治療のための神経由来胎児セルラインの使用
US5591625A (en) * 1993-11-24 1997-01-07 Case Western Reserve University Transduced mesenchymal stem cells
US5571083A (en) * 1994-02-18 1996-11-05 Lemelson; Jerome H. Method and system for cell transplantation
US5736396A (en) * 1995-01-24 1998-04-07 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
US6126936A (en) * 1995-03-10 2000-10-03 Biohybrid Technologies Llc Microcapsules and composite microreactors for immunoisolation of cells
DK0871457T3 (da) * 1995-03-28 2003-07-28 Univ Jefferson Isolerede stromaceller og fremgangsmåder til anvendelse heraf
US6653134B2 (en) * 1995-03-28 2003-11-25 Cp Hahnemann University Isolated stromal cells for use in the treatment of diseases of the central nervous system
US5716616A (en) * 1995-03-28 1998-02-10 Thomas Jefferson University Isolated stromal cells for treating diseases, disorders or conditions characterized by bone defects
US5842477A (en) * 1996-02-21 1998-12-01 Advanced Tissue Sciences, Inc. Method for repairing cartilage
US6342479B1 (en) * 1997-04-08 2002-01-29 Societe De Counseils De Recherches Et D'applications Scientifiques, Sas Prolonging survival of transplanted pancreatic cells
WO1999056759A1 (en) * 1998-05-07 1999-11-11 University Of South Florida Bone marrow cells as a source of neurons for brain and spinal cord repair
JP2002544234A (ja) * 1999-05-14 2002-12-24 ヘンリー フォード ヘルス システム 発作の処置のための骨髄移植
US20050169896A1 (en) * 1999-05-14 2005-08-04 Henry Ford Health System Bone marrow transplantation for treatment of stroke
US8017112B2 (en) * 1999-05-14 2011-09-13 Henry Ford Health System Transplantation of bone marrow stromal cells for treatment of neurodegenerative diseases
WO2007106200A2 (en) * 2006-01-10 2007-09-20 Theradigm, Inc. Expansion and differentiation of neural stem cells under low oxygen conditions

Similar Documents

Publication Publication Date Title
JP2002504503A5 (https=)
JP4848538B2 (ja) ヒトｃｎｓ神経幹細胞の培養
AU755657B2 (en) Lineage-restricted neuronal precursors
Studer et al. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats
JP4090692B2 (ja) 神経前駆細胞、その製造方法および神経性欠陥治療におけるその使用
JP4023822B2 (ja) ドーパミン作動性細胞のインビトロ誘導
JP3583778B2 (ja) 神経幹細胞の遺伝子修飾
Philips et al. Survival and integration of transplanted postmitotic human neurons following experimental brain injury in immunocompetent rats
US7361506B2 (en) Differentiation of specialized dermal and epidermal cells into neuronal cells
JPH08509215A (ja) 移植治療のための神経由来胎児セルラインの使用
US20130017179A1 (en) Lineage-Restricted Neuronal Precursors
JP2010209074A5 (https=)
US20020098584A1 (en) Postmortem stem cells
JP2004121258A (ja) 神経芽細胞の産生方法
CN1192781A (zh) 神经衍生胎儿细胞系在移植治疗中的应用
EP1278529B1 (en) Therapeutic uses for mesenchymal stromal cells
La Gamma et al. Genetically modified primary astrocytes as cellular vehicles for gene therapy in the brain
US6254865B1 (en) Method of treating huntington's disease using HNT neurons
KR100985191B1 (ko) 가역적으로 불멸화된 후각 초성 세포 및 신경세포 재생을촉진시키기 위한 그의 용도
US20040147020A1 (en) Dopamine neurons from human embryonic stem cells
EP2518141A1 (en) Stem cells derived from the carotid body and uses thereof
EP1231263A1 (en) Multipotent O-2A progenitors from the neurohypophysis
Cords 1.1. Ventral Horn Implants of hNT Neurons Improve Motor Function in a Transgenic Mouse Model of ALS. AE
EP1161523A1 (en) Cells, cell populations, and methods of making and using same