JP2002502410A - 上皮組織疾患の局所治療における窒素複素環式芳香族誘導体の使用 - Google Patents
上皮組織疾患の局所治療における窒素複素環式芳香族誘導体の使用Info
- Publication number
- JP2002502410A JP2002502410A JP50160699A JP50160699A JP2002502410A JP 2002502410 A JP2002502410 A JP 2002502410A JP 50160699 A JP50160699 A JP 50160699A JP 50160699 A JP50160699 A JP 50160699A JP 2002502410 A JP2002502410 A JP 2002502410A
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- JP
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- Prior art keywords
- derivative
- alkyl
- nitrogen
- general formula
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT97A001329 | 1997-06-05 | ||
| IT97MI001329A IT1292092B1 (it) | 1997-06-05 | 1997-06-05 | Impiego di derivati eterociclici aromatici azotati nel trattamento topico di affezioni di tessuti epiteliali |
| PCT/EP1998/003497 WO1998055118A2 (en) | 1997-06-05 | 1998-06-04 | Use of nitrogen heterocyclic aromatic derivatives in the topical treatment of the epithelial tissues diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2002502410A true JP2002502410A (ja) | 2002-01-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| JP50160699A Ceased JP2002502410A (ja) | 1997-06-05 | 1998-06-04 | 上皮組織疾患の局所治療における窒素複素環式芳香族誘導体の使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6323230B1 (enExample) |
| EP (1) | EP0986386B1 (enExample) |
| JP (1) | JP2002502410A (enExample) |
| AT (1) | ATE260655T1 (enExample) |
| AU (1) | AU8625598A (enExample) |
| CA (1) | CA2294547A1 (enExample) |
| DE (1) | DE69822153T2 (enExample) |
| DK (1) | DK0986386T3 (enExample) |
| ES (1) | ES2215315T3 (enExample) |
| IT (1) | IT1292092B1 (enExample) |
| PT (1) | PT986386E (enExample) |
| WO (1) | WO1998055118A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005529904A (ja) * | 2002-05-03 | 2005-10-06 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ | 自己免疫疾患の治療のための（３−（２−エチルフェニル）−５−メトキシフェニル）−１ｈ−［１，２，４］−トリアゾールの使用 |
| JP2014205687A (ja) * | 2008-05-30 | 2014-10-30 | 株式会社アールテック・ウエノ | ベンゼンまたはチオフェン誘導体およびｖａｐ−１阻害剤としてのその使用 |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6221897B1 (en) | 1998-06-10 | 2001-04-24 | Aventis Pharma Deutschland Gmbh | Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use |
| WO2002048144A1 (en) | 2000-12-13 | 2002-06-20 | Bayer Aktiengesellschaft | Pyrrolo (2.1-a) dihydroisoquinolines and their use as phosphodiesterase 10a inhibitors |
| WO2003014115A1 (en) * | 2001-08-06 | 2003-02-20 | Bayer Aktiengesellschaft | 3-substituted pyrrolo (2.1-a) isoquinoline derivatives |
| EP1838708A2 (en) * | 2005-01-12 | 2007-10-03 | Nycomed GmbH | Pyrrolodihydroisoquinolines as antiproliferative agents |
| HRP20120078T1 (hr) | 2006-10-31 | 2012-02-29 | Pfizer Products Inc. | Pirazolinski spojevi kao antagonisti mineralokortikoidnih receptora |
| PE20090305A1 (es) | 2007-05-22 | 2009-03-15 | Wyeth Corp | Proceso mejorado para la elaboracion de hidrazidas |
| EA030839B1 (ru) | 2011-10-28 | 2018-10-31 | ЛУМЕНА ФАРМАСЬЮТИКАЛС ЭлЭлСи | Ингибиторы рециклинга желчных кислот при лечении холестатических заболеваний печени у детей |
| WO2013063526A1 (en) | 2011-10-28 | 2013-05-02 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of hypercholemia and cholestatic liver disease |
| CN116514801B (zh) * | 2022-01-20 | 2024-11-08 | 四川大学 | 2-苯基-[1,2,4]三唑并[1,5-a]吡啶类化合物、其氮氧化物及用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1579352A (en) * | 1977-05-06 | 1980-11-19 | Lepetit Spa | 3,5-disubstituted-1h-1,2,4-triazoles |
| DE2961326D1 (en) | 1978-10-30 | 1982-01-14 | Lepetit Spa | New 1,2,4-triazole derivatives, a process for their manufacture and pharmaceutical compositions containing them |
| FI64151C (fi) | 1978-10-30 | 1983-10-10 | Lepetit Spa | Nya vid foedelsekontroll av daeggdjur anvaendbara 1h-1,2,4-triatzolderivat |
| US4379155A (en) * | 1979-06-11 | 1983-04-05 | Gruppo Lepetit S.P.A. | 3,5-Disubstituted-1H-1,2,4-triazole derivatives |
| AU557034B2 (en) * | 1981-10-20 | 1986-12-04 | Gruppo Lepetit S.P.A. | 3,5-diphenyl-1h-1,2,4-trazoles with contragestational |
| SE9300127L (sv) | 1993-01-19 | 1994-07-20 | Eyvind Langvad | Tricyliska kondenserade 1,2,4-triazoloderivat användbara såsom antiinflammatoriska medel |
| DE4320801A1 (de) | 1993-06-23 | 1995-01-05 | Fahlberg List Pharma Gmbh | 2-Hydroxyphenylsubstituierte 1,2,4-Triazole und 1,2,4-Oxadiazole, ihre Verwendung als pharmazeutische Wirkstoffe und sie enthaltende Arzneimittel |
| WO1995013268A1 (en) * | 1993-11-12 | 1995-05-18 | Gyógyszerkutató Intézet Kft. | Ulcer-inhibiting triazole derivatives, pharmaceutical compositions containing them and process for preparing same |
-
1997
- 1997-06-05 IT IT97MI001329A patent/IT1292092B1/it active IP Right Grant
-
1998
- 1998-06-04 AU AU86255/98A patent/AU8625598A/en not_active Abandoned
- 1998-06-04 WO PCT/EP1998/003497 patent/WO1998055118A2/en not_active Ceased
- 1998-06-04 DK DK98937464T patent/DK0986386T3/da active
- 1998-06-04 CA CA002294547A patent/CA2294547A1/en not_active Abandoned
- 1998-06-04 ES ES98937464T patent/ES2215315T3/es not_active Expired - Lifetime
- 1998-06-04 US US09/445,219 patent/US6323230B1/en not_active Expired - Fee Related
- 1998-06-04 PT PT98937464T patent/PT986386E/pt unknown
- 1998-06-04 AT AT98937464T patent/ATE260655T1/de not_active IP Right Cessation
- 1998-06-04 EP EP98937464A patent/EP0986386B1/en not_active Expired - Lifetime
- 1998-06-04 DE DE69822153T patent/DE69822153T2/de not_active Expired - Fee Related
- 1998-06-04 JP JP50160699A patent/JP2002502410A/ja not_active Ceased
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005529904A (ja) * | 2002-05-03 | 2005-10-06 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ | 自己免疫疾患の治療のための（３−（２−エチルフェニル）−５−メトキシフェニル）−１ｈ−［１，２，４］−トリアゾールの使用 |
| JP2014205687A (ja) * | 2008-05-30 | 2014-10-30 | 株式会社アールテック・ウエノ | ベンゼンまたはチオフェン誘導体およびｖａｐ−１阻害剤としてのその使用 |
| US9603833B2 (en) | 2008-05-30 | 2017-03-28 | R-Tech Ueno, Ltd. | Benzene or thiophene derivative and use thereof as VAP-1 inhibitor |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2294547A1 (en) | 1998-12-10 |
| US6323230B1 (en) | 2001-11-27 |
| ITMI971329A0 (enExample) | 1997-06-05 |
| DK0986386T3 (da) | 2004-07-12 |
| ES2215315T3 (es) | 2004-10-01 |
| ATE260655T1 (de) | 2004-03-15 |
| EP0986386B1 (en) | 2004-03-03 |
| DE69822153T2 (de) | 2005-01-27 |
| WO1998055118A3 (en) | 1999-04-15 |
| IT1292092B1 (it) | 1999-01-25 |
| ITMI971329A1 (it) | 1998-12-05 |
| WO1998055118A2 (en) | 1998-12-10 |
| DE69822153D1 (de) | 2004-04-08 |
| AU8625598A (en) | 1998-12-21 |
| EP0986386A2 (en) | 2000-03-22 |
| PT986386E (pt) | 2004-07-30 |
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