ATE260655T1 - Verwendung von stickstoffhaltigen aromatischen heterozyklusderivaten zur topischen behandlung von epithelerkrankungen - Google Patents
Verwendung von stickstoffhaltigen aromatischen heterozyklusderivaten zur topischen behandlung von epithelerkrankungenInfo
- Publication number
- ATE260655T1 ATE260655T1 AT98937464T AT98937464T ATE260655T1 AT E260655 T1 ATE260655 T1 AT E260655T1 AT 98937464 T AT98937464 T AT 98937464T AT 98937464 T AT98937464 T AT 98937464T AT E260655 T1 ATE260655 T1 AT E260655T1
- Authority
- AT
- Austria
- Prior art keywords
- diseases
- topical treatment
- epitheral
- nitrogen
- aromatic heterocycle
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 230000000699 topical effect Effects 0.000 title abstract 2
- 206010009900 Colitis ulcerative Diseases 0.000 abstract 2
- 201000004681 Psoriasis Diseases 0.000 abstract 2
- 201000006704 Ulcerative Colitis Diseases 0.000 abstract 2
- 210000000936 intestine Anatomy 0.000 abstract 2
- 208000011231 Crohn disease Diseases 0.000 abstract 1
- 206010012438 Dermatitis atopic Diseases 0.000 abstract 1
- 201000008937 atopic dermatitis Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 210000002615 epidermis Anatomy 0.000 abstract 1
- 210000000981 epithelium Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cosmetics (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT97MI001329A IT1292092B1 (it) | 1997-06-05 | 1997-06-05 | Impiego di derivati eterociclici aromatici azotati nel trattamento topico di affezioni di tessuti epiteliali |
| PCT/EP1998/003497 WO1998055118A2 (en) | 1997-06-05 | 1998-06-04 | Use of nitrogen heterocyclic aromatic derivatives in the topical treatment of the epithelial tissues diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE260655T1 true ATE260655T1 (de) | 2004-03-15 |
Family
ID=11377302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98937464T ATE260655T1 (de) | 1997-06-05 | 1998-06-04 | Verwendung von stickstoffhaltigen aromatischen heterozyklusderivaten zur topischen behandlung von epithelerkrankungen |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6323230B1 (enExample) |
| EP (1) | EP0986386B1 (enExample) |
| JP (1) | JP2002502410A (enExample) |
| AT (1) | ATE260655T1 (enExample) |
| AU (1) | AU8625598A (enExample) |
| CA (1) | CA2294547A1 (enExample) |
| DE (1) | DE69822153T2 (enExample) |
| DK (1) | DK0986386T3 (enExample) |
| ES (1) | ES2215315T3 (enExample) |
| IT (1) | IT1292092B1 (enExample) |
| PT (1) | PT986386E (enExample) |
| WO (1) | WO1998055118A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6221897B1 (en) | 1998-06-10 | 2001-04-24 | Aventis Pharma Deutschland Gmbh | Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use |
| US6930114B2 (en) | 2000-12-13 | 2005-08-16 | Bayer Pharmaceuticals Corporation | Pyrrolo (2.1a)dihydroisoquinolines and their use as phosphodiesterase 10a inhibitors |
| WO2003014115A1 (en) * | 2001-08-06 | 2003-02-20 | Bayer Aktiengesellschaft | 3-substituted pyrrolo (2.1-a) isoquinoline derivatives |
| US6797722B2 (en) * | 2002-05-03 | 2004-09-28 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole for the treatment of autoimmune diseases |
| AU2006205797A1 (en) * | 2005-01-12 | 2006-07-20 | 4Sc Ag | Pyrrolodihydroisoquinolines as antiproliferative agents |
| ES2375877T3 (es) | 2006-10-31 | 2012-03-07 | Pfizer Products Inc. | Compuestos de pirazolina como antagonistas de receptores de mineralocorticoides. |
| JP5697446B2 (ja) | 2007-05-22 | 2015-04-08 | ワイス・エルエルシー | ヒドラジドを製造するための改善されたプロセス |
| TWI490214B (zh) | 2008-05-30 | 2015-07-01 | 艾德克 上野股份有限公司 | 苯或噻吩衍生物及該等作為ｖａｐ－１抑制劑之用途 |
| EA038594B1 (ru) | 2011-10-28 | 2021-09-21 | Шайр Хьюман Дженетик Терапис, Инк. | Ингибиторы рециркуляции желчных кислот для лечения гиперхолемии и холестатического заболевания печени |
| JP6217938B2 (ja) | 2011-10-28 | 2017-10-25 | ルメナ ファーマシューティカルズ エルエルシー | 小児の胆汁うっ滞性肝疾患の処置のための胆汁酸再循環阻害剤 |
| CN116514801B (zh) * | 2022-01-20 | 2024-11-08 | 四川大学 | 2-苯基-[1,2,4]三唑并[1,5-a]吡啶类化合物、其氮氧化物及用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1579352A (en) * | 1977-05-06 | 1980-11-19 | Lepetit Spa | 3,5-disubstituted-1h-1,2,4-triazoles |
| EP0011129B1 (en) | 1978-10-30 | 1981-11-11 | Gruppo Lepetit S.P.A. | New 1,2,4-triazole derivatives, a process for their manufacture and pharmaceutical compositions containing them |
| FI64151C (fi) | 1978-10-30 | 1983-10-10 | Lepetit Spa | Nya vid foedelsekontroll av daeggdjur anvaendbara 1h-1,2,4-triatzolderivat |
| US4379155A (en) * | 1979-06-11 | 1983-04-05 | Gruppo Lepetit S.P.A. | 3,5-Disubstituted-1H-1,2,4-triazole derivatives |
| AU557034B2 (en) | 1981-10-20 | 1986-12-04 | Gruppo Lepetit S.P.A. | 3,5-diphenyl-1h-1,2,4-trazoles with contragestational |
| SE9300127L (sv) | 1993-01-19 | 1994-07-20 | Eyvind Langvad | Tricyliska kondenserade 1,2,4-triazoloderivat användbara såsom antiinflammatoriska medel |
| DE4320801A1 (de) * | 1993-06-23 | 1995-01-05 | Fahlberg List Pharma Gmbh | 2-Hydroxyphenylsubstituierte 1,2,4-Triazole und 1,2,4-Oxadiazole, ihre Verwendung als pharmazeutische Wirkstoffe und sie enthaltende Arzneimittel |
| WO1995013268A1 (en) * | 1993-11-12 | 1995-05-18 | Gyógyszerkutató Intézet Kft. | Ulcer-inhibiting triazole derivatives, pharmaceutical compositions containing them and process for preparing same |
-
1997
- 1997-06-05 IT IT97MI001329A patent/IT1292092B1/it active IP Right Grant
-
1998
- 1998-06-04 CA CA002294547A patent/CA2294547A1/en not_active Abandoned
- 1998-06-04 DE DE69822153T patent/DE69822153T2/de not_active Expired - Fee Related
- 1998-06-04 WO PCT/EP1998/003497 patent/WO1998055118A2/en not_active Ceased
- 1998-06-04 EP EP98937464A patent/EP0986386B1/en not_active Expired - Lifetime
- 1998-06-04 JP JP50160699A patent/JP2002502410A/ja not_active Ceased
- 1998-06-04 ES ES98937464T patent/ES2215315T3/es not_active Expired - Lifetime
- 1998-06-04 PT PT98937464T patent/PT986386E/pt unknown
- 1998-06-04 DK DK98937464T patent/DK0986386T3/da active
- 1998-06-04 AT AT98937464T patent/ATE260655T1/de not_active IP Right Cessation
- 1998-06-04 US US09/445,219 patent/US6323230B1/en not_active Expired - Fee Related
- 1998-06-04 AU AU86255/98A patent/AU8625598A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PT986386E (pt) | 2004-07-30 |
| JP2002502410A (ja) | 2002-01-22 |
| EP0986386A2 (en) | 2000-03-22 |
| DE69822153D1 (de) | 2004-04-08 |
| WO1998055118A2 (en) | 1998-12-10 |
| IT1292092B1 (it) | 1999-01-25 |
| DE69822153T2 (de) | 2005-01-27 |
| WO1998055118A3 (en) | 1999-04-15 |
| ITMI971329A1 (it) | 1998-12-05 |
| US6323230B1 (en) | 2001-11-27 |
| ES2215315T3 (es) | 2004-10-01 |
| EP0986386B1 (en) | 2004-03-03 |
| AU8625598A (en) | 1998-12-21 |
| CA2294547A1 (en) | 1998-12-10 |
| DK0986386T3 (da) | 2004-07-12 |
| ITMI971329A0 (enExample) | 1997-06-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0986386 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |