JP2002501785A5 - - Google Patents
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- Publication number
- JP2002501785A5 JP2002501785A5 JP2000529273A JP2000529273A JP2002501785A5 JP 2002501785 A5 JP2002501785 A5 JP 2002501785A5 JP 2000529273 A JP2000529273 A JP 2000529273A JP 2000529273 A JP2000529273 A JP 2000529273A JP 2002501785 A5 JP2002501785 A5 JP 2002501785A5
- Authority
- JP
- Japan
- Prior art keywords
- biomaterial
- compound
- compound according
- biomaterial compound
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 150000001875 compounds Chemical class 0.000 claims 39
- 239000012620 biological material Substances 0.000 claims 36
- 239000000203 mixture Substances 0.000 claims 10
- 239000011575 calcium Substances 0.000 claims 7
- 241001465754 Metazoa Species 0.000 claims 5
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims 5
- 229910052791 calcium Inorganic materials 0.000 claims 5
- 229910052698 phosphorus Inorganic materials 0.000 claims 5
- 239000011574 phosphorus Substances 0.000 claims 5
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 4
- 210000000988 bone and bone Anatomy 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 4
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims 3
- 229910052710 silicon Inorganic materials 0.000 claims 3
- 239000010703 silicon Substances 0.000 claims 3
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical group [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 claims 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 210000002805 bone matrix Anatomy 0.000 claims 2
- 229910052796 boron Inorganic materials 0.000 claims 2
- 239000011248 coating agent Substances 0.000 claims 2
- 238000000576 coating method Methods 0.000 claims 2
- 210000000963 osteoblast Anatomy 0.000 claims 2
- 210000002997 osteoclast Anatomy 0.000 claims 2
- 239000001301 oxygen Substances 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims 2
- 102000008186 Collagen Human genes 0.000 claims 1
- 108010035532 Collagen Proteins 0.000 claims 1
- 235000019739 Dicalciumphosphate Nutrition 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 claims 1
- 239000000292 calcium oxide Substances 0.000 claims 1
- ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 claims 1
- 239000001506 calcium phosphate Substances 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 229920001436 collagen Polymers 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- NEFBYIFKOOEVPA-UHFFFAOYSA-K dicalcium phosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])([O-])=O NEFBYIFKOOEVPA-UHFFFAOYSA-K 0.000 claims 1
- 229910000390 dicalcium phosphate Inorganic materials 0.000 claims 1
- 229940038472 dicalcium phosphate Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 230000007774 longterm Effects 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 229910000392 octacalcium phosphate Inorganic materials 0.000 claims 1
- 230000000399 orthopedic effect Effects 0.000 claims 1
- 239000008188 pellet Substances 0.000 claims 1
- 239000006069 physical mixture Substances 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 239000011148 porous material Substances 0.000 claims 1
- 238000000197 pyrolysis Methods 0.000 claims 1
- 239000006104 solid solution Substances 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- YIGWVOWKHUSYER-UHFFFAOYSA-F tetracalcium;hydrogen phosphate;diphosphate Chemical compound [Ca+2].[Ca+2].[Ca+2].[Ca+2].OP([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O YIGWVOWKHUSYER-UHFFFAOYSA-F 0.000 claims 1
- GBNXLQPMFAUCOI-UHFFFAOYSA-H tetracalcium;oxygen(2-);diphosphate Chemical compound [O-2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O GBNXLQPMFAUCOI-UHFFFAOYSA-H 0.000 claims 1
- 229920001187 thermosetting polymer Polymers 0.000 claims 1
- 239000010409 thin film Substances 0.000 claims 1
- 230000008733 trauma Effects 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CA1998/000046 WO1999038542A1 (en) | 1998-01-29 | 1998-01-29 | A synthetic biomaterial compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002501785A JP2002501785A (ja) | 2002-01-22 |
| JP2002501785A5 true JP2002501785A5 (enExample) | 2005-06-23 |
Family
ID=4173269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000529273A Pending JP2002501785A (ja) | 1998-01-29 | 1998-01-29 | 合成生体材料化合物 |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1056486B1 (enExample) |
| JP (1) | JP2002501785A (enExample) |
| KR (1) | KR100652511B1 (enExample) |
| CN (1) | CN100569301C (enExample) |
| AU (1) | AU760561B2 (enExample) |
| BR (1) | BR9815668A (enExample) |
| CA (1) | CA2318085C (enExample) |
| DE (1) | DE69836151T2 (enExample) |
| ES (1) | ES2274563T3 (enExample) |
| NZ (1) | NZ505765A (enExample) |
| WO (1) | WO1999038542A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001259016A (ja) * | 2000-03-17 | 2001-09-25 | Olympus Optical Co Ltd | β−リン酸三カルシウム骨補填材 |
| DE60219646T2 (de) * | 2001-09-24 | 2007-12-27 | Millenium Biologix Technologies Inc., Kingston | Poröse keramische komposit-knochenimplantate |
| TW200400062A (en) * | 2002-04-03 | 2004-01-01 | Mathys Medizinaltechnik Ag | Kneadable, pliable bone replacement material |
| CA2485350C (en) * | 2002-04-08 | 2014-08-19 | Millenium Biologix Inc. | Automated tissue engineering system comprising sensors linked to a microprocessor |
| FR2842750B1 (fr) * | 2002-07-26 | 2004-10-08 | Toulouse Inst Nat Polytech | Procede permettant de recouvrir a basse temperature des surfaces par des phosphates apatitiques nanocristallins, a partir d'une suspension aqueuse de phosphate amorphe |
| WO2004096140A2 (en) | 2003-04-25 | 2004-11-11 | The Penn State Research Foundation | Method and system for systemic delivery of growth arresting, lipid-derived bioactive compounds |
| GB0311221D0 (en) | 2003-05-15 | 2003-06-18 | Orthogem Ltd | Biomaterial |
| GB0900269D0 (en) | 2009-01-08 | 2009-02-11 | Univ Aberdeen | Silicate-substituted hydroxyapatite |
| PL210026B1 (pl) * | 2009-03-17 | 2011-11-30 | Akademia Górniczo Hutnicza Im Stanisława Staszica | Sposób wytwarzania wysokoporowatego, fosforanowo-wapniowego bioaktywnego tworzywa implantacyjnego |
| JP6061415B2 (ja) * | 2010-04-30 | 2017-01-18 | 学校法人千葉工業大学 | β型リン酸三カルシウムからなる生体材料セラミックス及びその製造方法 |
| KR101423982B1 (ko) | 2012-08-10 | 2014-08-13 | 서울대학교산학협력단 | 휘트록카이트 및 그 제조 방법 |
| US9238090B1 (en) | 2014-12-24 | 2016-01-19 | Fettech, Llc | Tissue-based compositions |
| JP2017060779A (ja) * | 2016-10-08 | 2017-03-30 | 学校法人千葉工業大学 | β型リン酸三カルシウムからなる生体材料セラミックス及びその製造方法 |
| JP2024513147A (ja) * | 2021-01-26 | 2024-03-22 | メルツ ノース アメリカ，インコーポレイテッド | カルシウムハイドロキシアパタイト粒子およびその使用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4503157A (en) * | 1982-09-25 | 1985-03-05 | Ina Seito Co., Ltd. | Sintered apatite bodies and composites thereof |
| US5074916A (en) * | 1990-05-18 | 1991-12-24 | Geltech, Inc. | Alkali-free bioactive sol-gel compositions |
| FR2664501B1 (fr) * | 1990-07-16 | 1995-05-12 | Osteal Medical Laboratoires | Materiau composite pour implant osseux et procede de mise en óoeuvre comme revetement. |
| GB9310194D0 (en) * | 1993-05-18 | 1993-06-30 | Millenium Bioligix Inc | Assessment of osteoclast activity |
| GB2302656B (en) * | 1994-05-24 | 1998-03-18 | Implico Bv | A biomaterial and bone implant for bone repair and replacement |
| CA2230057C (en) * | 1995-09-01 | 2008-10-21 | Millenium Biologix, Inc. | An artificial stabilized composition of calcium phosphate phases particularly adapted for supporting bone cell activity |
| GB2316940A (en) * | 1996-08-30 | 1998-03-11 | Queen Mary & Westfield College | Silicon-substituted hydroxyapatite |
-
1998
- 1998-01-29 CN CNB98813358XA patent/CN100569301C/zh not_active Expired - Fee Related
- 1998-01-29 BR BR9815668-3A patent/BR9815668A/pt not_active Application Discontinuation
- 1998-01-29 CA CA2318085A patent/CA2318085C/en not_active Expired - Fee Related
- 1998-01-29 WO PCT/CA1998/000046 patent/WO1999038542A1/en not_active Ceased
- 1998-01-29 EP EP98901283A patent/EP1056486B1/en not_active Expired - Lifetime
- 1998-01-29 AU AU57445/98A patent/AU760561B2/en not_active Ceased
- 1998-01-29 JP JP2000529273A patent/JP2002501785A/ja active Pending
- 1998-01-29 DE DE69836151T patent/DE69836151T2/de not_active Expired - Lifetime
- 1998-01-29 NZ NZ505765A patent/NZ505765A/en unknown
- 1998-01-29 KR KR1020007008283A patent/KR100652511B1/ko not_active Expired - Lifetime
- 1998-01-29 ES ES98901283T patent/ES2274563T3/es not_active Expired - Lifetime
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