DE69836151T2 - Synthetisches biomaterial - Google Patents
Synthetisches biomaterial Download PDFInfo
- Publication number
- DE69836151T2 DE69836151T2 DE69836151T DE69836151T DE69836151T2 DE 69836151 T2 DE69836151 T2 DE 69836151T2 DE 69836151 T DE69836151 T DE 69836151T DE 69836151 T DE69836151 T DE 69836151T DE 69836151 T2 DE69836151 T2 DE 69836151T2
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- biomaterial
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- 239000012620 biological material Substances 0.000 title claims description 69
- 150000001875 compounds Chemical class 0.000 claims description 134
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 87
- 239000000843 powder Substances 0.000 claims description 72
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- 210000000988 bone and bone Anatomy 0.000 claims description 65
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 56
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- YIGWVOWKHUSYER-UHFFFAOYSA-F tetracalcium;hydrogen phosphate;diphosphate Chemical compound [Ca+2].[Ca+2].[Ca+2].[Ca+2].OP([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O YIGWVOWKHUSYER-UHFFFAOYSA-F 0.000 claims description 7
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- NEFBYIFKOOEVPA-UHFFFAOYSA-K dicalcium phosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])([O-])=O NEFBYIFKOOEVPA-UHFFFAOYSA-K 0.000 claims description 4
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B35/00—Boron; Compounds thereof
- C01B35/08—Compounds containing boron and nitrogen, phosphorus, oxygen, sulfur, selenium or tellurium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/32—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B33/00—Silicon; Compounds thereof
- C01B33/20—Silicates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
- A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
- A61F2310/00796—Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Silicates, Zeolites, And Molecular Sieves (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CA1998/000046 WO1999038542A1 (en) | 1998-01-29 | 1998-01-29 | A synthetic biomaterial compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69836151D1 DE69836151D1 (de) | 2006-11-23 |
| DE69836151T2 true DE69836151T2 (de) | 2007-02-01 |
Family
ID=4173269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69836151T Expired - Lifetime DE69836151T2 (de) | 1998-01-29 | 1998-01-29 | Synthetisches biomaterial |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1056486B1 (enExample) |
| JP (1) | JP2002501785A (enExample) |
| KR (1) | KR100652511B1 (enExample) |
| CN (1) | CN100569301C (enExample) |
| AU (1) | AU760561B2 (enExample) |
| BR (1) | BR9815668A (enExample) |
| CA (1) | CA2318085C (enExample) |
| DE (1) | DE69836151T2 (enExample) |
| ES (1) | ES2274563T3 (enExample) |
| NZ (1) | NZ505765A (enExample) |
| WO (1) | WO1999038542A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001259016A (ja) * | 2000-03-17 | 2001-09-25 | Olympus Optical Co Ltd | β−リン酸三カルシウム骨補填材 |
| DE60219646T2 (de) * | 2001-09-24 | 2007-12-27 | Millenium Biologix Technologies Inc., Kingston | Poröse keramische komposit-knochenimplantate |
| TW200400062A (en) * | 2002-04-03 | 2004-01-01 | Mathys Medizinaltechnik Ag | Kneadable, pliable bone replacement material |
| CA2485350C (en) * | 2002-04-08 | 2014-08-19 | Millenium Biologix Inc. | Automated tissue engineering system comprising sensors linked to a microprocessor |
| FR2842750B1 (fr) * | 2002-07-26 | 2004-10-08 | Toulouse Inst Nat Polytech | Procede permettant de recouvrir a basse temperature des surfaces par des phosphates apatitiques nanocristallins, a partir d'une suspension aqueuse de phosphate amorphe |
| WO2004096140A2 (en) | 2003-04-25 | 2004-11-11 | The Penn State Research Foundation | Method and system for systemic delivery of growth arresting, lipid-derived bioactive compounds |
| GB0311221D0 (en) | 2003-05-15 | 2003-06-18 | Orthogem Ltd | Biomaterial |
| GB0900269D0 (en) | 2009-01-08 | 2009-02-11 | Univ Aberdeen | Silicate-substituted hydroxyapatite |
| PL210026B1 (pl) * | 2009-03-17 | 2011-11-30 | Akademia Górniczo Hutnicza Im Stanisława Staszica | Sposób wytwarzania wysokoporowatego, fosforanowo-wapniowego bioaktywnego tworzywa implantacyjnego |
| JP6061415B2 (ja) * | 2010-04-30 | 2017-01-18 | 学校法人千葉工業大学 | β型リン酸三カルシウムからなる生体材料セラミックス及びその製造方法 |
| KR101423982B1 (ko) | 2012-08-10 | 2014-08-13 | 서울대학교산학협력단 | 휘트록카이트 및 그 제조 방법 |
| US9238090B1 (en) | 2014-12-24 | 2016-01-19 | Fettech, Llc | Tissue-based compositions |
| JP2017060779A (ja) * | 2016-10-08 | 2017-03-30 | 学校法人千葉工業大学 | β型リン酸三カルシウムからなる生体材料セラミックス及びその製造方法 |
| JP2024513147A (ja) * | 2021-01-26 | 2024-03-22 | メルツ ノース アメリカ，インコーポレイテッド | カルシウムハイドロキシアパタイト粒子およびその使用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4503157A (en) * | 1982-09-25 | 1985-03-05 | Ina Seito Co., Ltd. | Sintered apatite bodies and composites thereof |
| US5074916A (en) * | 1990-05-18 | 1991-12-24 | Geltech, Inc. | Alkali-free bioactive sol-gel compositions |
| FR2664501B1 (fr) * | 1990-07-16 | 1995-05-12 | Osteal Medical Laboratoires | Materiau composite pour implant osseux et procede de mise en óoeuvre comme revetement. |
| GB9310194D0 (en) * | 1993-05-18 | 1993-06-30 | Millenium Bioligix Inc | Assessment of osteoclast activity |
| GB2302656B (en) * | 1994-05-24 | 1998-03-18 | Implico Bv | A biomaterial and bone implant for bone repair and replacement |
| CA2230057C (en) * | 1995-09-01 | 2008-10-21 | Millenium Biologix, Inc. | An artificial stabilized composition of calcium phosphate phases particularly adapted for supporting bone cell activity |
| GB2316940A (en) * | 1996-08-30 | 1998-03-11 | Queen Mary & Westfield College | Silicon-substituted hydroxyapatite |
-
1998
- 1998-01-29 CN CNB98813358XA patent/CN100569301C/zh not_active Expired - Fee Related
- 1998-01-29 BR BR9815668-3A patent/BR9815668A/pt not_active Application Discontinuation
- 1998-01-29 CA CA2318085A patent/CA2318085C/en not_active Expired - Fee Related
- 1998-01-29 WO PCT/CA1998/000046 patent/WO1999038542A1/en not_active Ceased
- 1998-01-29 EP EP98901283A patent/EP1056486B1/en not_active Expired - Lifetime
- 1998-01-29 AU AU57445/98A patent/AU760561B2/en not_active Ceased
- 1998-01-29 JP JP2000529273A patent/JP2002501785A/ja active Pending
- 1998-01-29 DE DE69836151T patent/DE69836151T2/de not_active Expired - Lifetime
- 1998-01-29 NZ NZ505765A patent/NZ505765A/en unknown
- 1998-01-29 KR KR1020007008283A patent/KR100652511B1/ko not_active Expired - Lifetime
- 1998-01-29 ES ES98901283T patent/ES2274563T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU5744598A (en) | 1999-08-16 |
| DE69836151D1 (de) | 2006-11-23 |
| ES2274563T3 (es) | 2007-05-16 |
| BR9815668A (pt) | 2001-01-30 |
| AU760561B2 (en) | 2003-05-15 |
| NZ505765A (en) | 2003-09-26 |
| CA2318085C (en) | 2012-05-01 |
| WO1999038542A1 (en) | 1999-08-05 |
| JP2002501785A (ja) | 2002-01-22 |
| EP1056486A1 (en) | 2000-12-06 |
| KR100652511B1 (ko) | 2006-11-30 |
| EP1056486B1 (en) | 2006-10-11 |
| CN100569301C (zh) | 2009-12-16 |
| CA2318085A1 (en) | 1999-08-05 |
| KR20010106090A (ko) | 2001-11-29 |
| CN1307490A (zh) | 2001-08-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: MILLENIUM BIOLOGIX TECHNOLOGIES INC., KINGSTON, CA |
|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: WARSAW ORTHOPEDIC, INC., MINNEAPOLIS, MINN., US |