JP2002501491A - 外来・異種遺伝子を有する繊維芽細胞を含んでなる創傷治癒組成物 - Google Patents

外来・異種遺伝子を有する繊維芽細胞を含んでなる創傷治癒組成物

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Publication number
JP2002501491A
JP2002501491A JP54493298A JP54493298A JP2002501491A JP 2002501491 A JP2002501491 A JP 2002501491A JP 54493298 A JP54493298 A JP 54493298A JP 54493298 A JP54493298 A JP 54493298A JP 2002501491 A JP2002501491 A JP 2002501491A
Authority
JP
Japan
Prior art keywords
composition
fibroblast
gene
growth factor
egf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP54493298A
Other languages
English (en)
Japanese (ja)
Inventor
メーテルスマン、ローラント
ローゼンタール、フェリシア
クルムブルク、ペーター
スターク、ビョルン・ゲー
タンチョス、エスツター
コップ、ユルゲン
Original Assignee
クリニクーム・デア・アルバート−ルドヴィッヒス−ウニヴェルズィテート・フライブルク
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by クリニクーム・デア・アルバート−ルドヴィッヒス−ウニヴェルズィテート・フライブルク filed Critical クリニクーム・デア・アルバート−ルドヴィッヒス−ウニヴェルズィテート・フライブルク
Publication of JP2002501491A publication Critical patent/JP2002501491A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0656Adult fibroblasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP54493298A 1997-04-17 1998-04-08 外来・異種遺伝子を有する繊維芽細胞を含んでなる創傷治癒組成物 Pending JP2002501491A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19716098.0 1997-04-17
DE19716098A DE19716098A1 (de) 1997-04-17 1997-04-17 Fibroblasten mit einem Fremdgen enthaltende Zusammensetzung zur Behandlung von Wunden
PCT/EP1998/002038 WO1998048012A1 (de) 1997-04-17 1998-04-08 Fibroblasten mit einem fremdgen enthaltende zusammensetzung zur behandlung von wunden

Publications (1)

Publication Number Publication Date
JP2002501491A true JP2002501491A (ja) 2002-01-15

Family

ID=7826816

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54493298A Pending JP2002501491A (ja) 1997-04-17 1998-04-08 外来・異種遺伝子を有する繊維芽細胞を含んでなる創傷治癒組成物

Country Status (7)

Country Link
EP (1) EP0975756A1 (de)
JP (1) JP2002501491A (de)
AU (1) AU739125B2 (de)
CA (1) CA2286548A1 (de)
DE (1) DE19716098A1 (de)
IL (1) IL131636A0 (de)
WO (1) WO1998048012A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6277368B1 (en) 1996-07-25 2001-08-21 The Regents Of The University Of California Cancer immunotherapy using autologous tumor cells combined with cells expressing a membrane cytokine
AU5301100A (en) 1999-05-28 2000-12-18 Pacgen Technologies Llc A method of using autologous fibroblasts to promote healing of wounds and fistulas
DE10025609A1 (de) * 2000-05-24 2001-12-13 Univ Ludwigs Albert Transfektionssystem
WO2014105913A1 (en) * 2012-12-26 2014-07-03 The Regents Of The University Of California Cellular compositions for tissue engineering

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4609551A (en) * 1984-03-20 1986-09-02 Arnold Caplan Process of and material for stimulating growth of cartilage and bony tissue at anatomical sites
EP0213908A3 (de) * 1985-08-26 1989-03-22 Hana Biologics, Inc. Transplantierbares Kunstgewebe und Verfahren
US5196196A (en) * 1986-06-03 1993-03-23 Incyte Pharmaceuticals, Inc. Use of protease nexin-I in wound dressings
ATE197800T1 (de) * 1989-01-31 2000-12-15 Jeffrey S Rubin Dns kodierend für einen für epithelzellen spezifischen wachstumsfaktor
WO1992015676A1 (en) * 1991-03-08 1992-09-17 The Salk Institute For Biological Studies Somatic cell gene therapy
JP2829405B2 (ja) * 1991-10-14 1998-11-25 寳酒造株式会社 機能性ポリペプチド
JPH09504786A (ja) * 1993-09-07 1997-05-13 シドニー キンメル キャンサー センター ハプロタイプ適合サイトカイン分泌細胞および免疫応答を刺激するための使用方法
DE4406073A1 (de) * 1994-02-24 1995-08-31 Univ Ludwigs Albert Verfahren zur Herstellung von humanen, klonogenen Fibroblasten, Verfahren zur Gentransfizierung von Fibroblasten und so erhaltene Fibroblasten

Also Published As

Publication number Publication date
IL131636A0 (en) 2001-01-28
WO1998048012A1 (de) 1998-10-29
DE19716098A1 (de) 1998-10-22
AU739125B2 (en) 2001-10-04
CA2286548A1 (en) 1998-10-29
EP0975756A1 (de) 2000-02-02
AU7215098A (en) 1998-11-13

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