CA2286548A1 - Fibroblasts with a foreign gene-containing composition for treating wounds - Google Patents

Fibroblasts with a foreign gene-containing composition for treating wounds Download PDF

Info

Publication number
CA2286548A1
CA2286548A1 CA002286548A CA2286548A CA2286548A1 CA 2286548 A1 CA2286548 A1 CA 2286548A1 CA 002286548 A CA002286548 A CA 002286548A CA 2286548 A CA2286548 A CA 2286548A CA 2286548 A1 CA2286548 A1 CA 2286548A1
Authority
CA
Canada
Prior art keywords
fibroblasts
composition according
growth factor
gene
egf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002286548A
Other languages
English (en)
French (fr)
Inventor
Roland Mertelsmann
Felicia Rosenthal
Peter Kulmburg
Bjorn Stark
Eszter Tanczos
Jurgen Kopp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitaetsklinikum Freiburg
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2286548A1 publication Critical patent/CA2286548A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0656—Adult fibroblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA002286548A 1997-04-17 1998-04-08 Fibroblasts with a foreign gene-containing composition for treating wounds Abandoned CA2286548A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19716098.0 1997-04-17
DE19716098A DE19716098A1 (de) 1997-04-17 1997-04-17 Fibroblasten mit einem Fremdgen enthaltende Zusammensetzung zur Behandlung von Wunden
PCT/EP1998/002038 WO1998048012A1 (de) 1997-04-17 1998-04-08 Fibroblasten mit einem fremdgen enthaltende zusammensetzung zur behandlung von wunden

Publications (1)

Publication Number Publication Date
CA2286548A1 true CA2286548A1 (en) 1998-10-29

Family

ID=7826816

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002286548A Abandoned CA2286548A1 (en) 1997-04-17 1998-04-08 Fibroblasts with a foreign gene-containing composition for treating wounds

Country Status (7)

Country Link
EP (1) EP0975756A1 (de)
JP (1) JP2002501491A (de)
AU (1) AU739125B2 (de)
CA (1) CA2286548A1 (de)
DE (1) DE19716098A1 (de)
IL (1) IL131636A0 (de)
WO (1) WO1998048012A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007201342B2 (en) * 2000-05-24 2009-01-08 Universitatsklinikum Freiburg Transfection System

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6277368B1 (en) 1996-07-25 2001-08-21 The Regents Of The University Of California Cancer immunotherapy using autologous tumor cells combined with cells expressing a membrane cytokine
AU5301100A (en) 1999-05-28 2000-12-18 Pacgen Technologies Llc A method of using autologous fibroblasts to promote healing of wounds and fistulas
WO2014105913A1 (en) * 2012-12-26 2014-07-03 The Regents Of The University Of California Cellular compositions for tissue engineering

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4609551A (en) * 1984-03-20 1986-09-02 Arnold Caplan Process of and material for stimulating growth of cartilage and bony tissue at anatomical sites
EP0213908A3 (de) * 1985-08-26 1989-03-22 Hana Biologics, Inc. Transplantierbares Kunstgewebe und Verfahren
US5196196A (en) * 1986-06-03 1993-03-23 Incyte Pharmaceuticals, Inc. Use of protease nexin-I in wound dressings
ATE197800T1 (de) * 1989-01-31 2000-12-15 Jeffrey S Rubin Dns kodierend für einen für epithelzellen spezifischen wachstumsfaktor
WO1992015676A1 (en) * 1991-03-08 1992-09-17 The Salk Institute For Biological Studies Somatic cell gene therapy
JP2829405B2 (ja) * 1991-10-14 1998-11-25 寳酒造株式会社 機能性ポリペプチド
JPH09504786A (ja) * 1993-09-07 1997-05-13 シドニー キンメル キャンサー センター ハプロタイプ適合サイトカイン分泌細胞および免疫応答を刺激するための使用方法
DE4406073A1 (de) * 1994-02-24 1995-08-31 Univ Ludwigs Albert Verfahren zur Herstellung von humanen, klonogenen Fibroblasten, Verfahren zur Gentransfizierung von Fibroblasten und so erhaltene Fibroblasten

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007201342B2 (en) * 2000-05-24 2009-01-08 Universitatsklinikum Freiburg Transfection System

Also Published As

Publication number Publication date
IL131636A0 (en) 2001-01-28
WO1998048012A1 (de) 1998-10-29
DE19716098A1 (de) 1998-10-22
AU739125B2 (en) 2001-10-04
EP0975756A1 (de) 2000-02-02
JP2002501491A (ja) 2002-01-15
AU7215098A (en) 1998-11-13

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Legal Events

Date Code Title Description
FZDE Discontinued