JP2001522835A5 - - Google Patents
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- Publication number
- JP2001522835A5 JP2001522835A5 JP2000520419A JP2000520419A JP2001522835A5 JP 2001522835 A5 JP2001522835 A5 JP 2001522835A5 JP 2000520419 A JP2000520419 A JP 2000520419A JP 2000520419 A JP2000520419 A JP 2000520419A JP 2001522835 A5 JP2001522835 A5 JP 2001522835A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- descarboethoxyloratadine
- fexofenadine
- loratadine
- cetirizine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000001875 compounds Chemical class 0.000 description 2
- 239000000938 histamine H1 antagonist Substances 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- ZKLPARSLTMPFCP-UHFFFAOYSA-N Cetirizine Chemical compound C1CN(CCOCC(=O)O)CCN1C(C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 ZKLPARSLTMPFCP-UHFFFAOYSA-N 0.000 description 1
- JAUOIFJMECXRGI-UHFFFAOYSA-N Neoclaritin Chemical compound C=1C(Cl)=CC=C2C=1CCC1=CC=CN=C1C2=C1CCNCC1 JAUOIFJMECXRGI-UHFFFAOYSA-N 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 229960001803 cetirizine Drugs 0.000 description 1
- 229960001271 desloratadine Drugs 0.000 description 1
- 229960003592 fexofenadine Drugs 0.000 description 1
- RWTNPBWLLIMQHL-UHFFFAOYSA-N fexofenadine Chemical compound C1=CC(C(C)(C(O)=O)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 RWTNPBWLLIMQHL-UHFFFAOYSA-N 0.000 description 1
- 229960003088 loratadine Drugs 0.000 description 1
- JCCNYMKQOSZNPW-UHFFFAOYSA-N loratadine Chemical group C1CN(C(=O)OCC)CCC1=C1C2=NC=CC=C2CCC2=CC(Cl)=CC=C21 JCCNYMKQOSZNPW-UHFFFAOYSA-N 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000012453 solvate Substances 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96634497A | 1997-11-07 | 1997-11-07 | |
| US12971198A | 1998-08-05 | 1998-08-05 | |
| US08/966,344 | 1998-08-05 | ||
| US09/129,711 | 1998-08-05 | ||
| PCT/US1998/023223 WO1999024405A1 (en) | 1997-11-07 | 1998-11-05 | H3 receptor ligands of the phenyl-alkyl-imidazoles type |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001522835A JP2001522835A (ja) | 2001-11-20 |
| JP2001522835A5 true JP2001522835A5 (https=) | 2006-01-05 |
Family
ID=26827847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000520419A Ceased JP2001522835A (ja) | 1997-11-07 | 1998-11-05 | フェニル−アルキル−イミダゾール型のｈ３レセプターリガンド |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1028947B8 (https=) |
| JP (1) | JP2001522835A (https=) |
| KR (1) | KR20010031724A (https=) |
| CN (1) | CN1130349C (https=) |
| AR (1) | AR016672A1 (https=) |
| AT (1) | ATE219062T1 (https=) |
| AU (1) | AU1296699A (https=) |
| CA (1) | CA2308586A1 (https=) |
| CO (1) | CO5011065A1 (https=) |
| DE (1) | DE69806042T2 (https=) |
| ES (1) | ES2174510T3 (https=) |
| HU (1) | HUP0004292A3 (https=) |
| IL (1) | IL135729A0 (https=) |
| NZ (1) | NZ504124A (https=) |
| PE (1) | PE134399A1 (https=) |
| TW (1) | TW421645B (https=) |
| WO (1) | WO1999024405A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20020507A1 (es) | 2000-10-17 | 2002-06-25 | Schering Corp | Compuestos no-imidazoles como antagonistas del receptor histamina h3 |
| EP1373251A2 (en) | 2001-03-13 | 2004-01-02 | Schering Corporation | Non-imidazole compounds as histamine h3 antagonists |
| JP4690889B2 (ja) * | 2002-10-24 | 2011-06-01 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | メチレン尿素誘導体 |
| AU2006204724A1 (en) | 2005-01-14 | 2006-07-20 | Millennium Pharmaceuticals, Inc. | Cinnamide and hydrocinnamide derivatives with raf-kinase inhibitory activity |
| EP1749523A1 (en) * | 2005-07-29 | 2007-02-07 | Neuropharma, S.A. | GSK-3 inhibitors |
| JP4860700B2 (ja) | 2005-09-20 | 2012-01-25 | シェーリング コーポレイション | ヒスタミンＨ３アンタゴニストとして有用な、１−［［１−［（２−アミノ−６−メチル−４−ピリジニル）メチル］−４−フルオロ−４−ピペリジニル］カルボニル］−４−［２−（２−ピリジニル）−３Ｈ−イミダゾ［４，５−ｂ］ピリジン−３−イル］ピペリジン |
| US20150225369A1 (en) * | 2012-08-29 | 2015-08-13 | Merck Patent Gmbh | Ddr2 inhibitors for the treatment of osteoarthritis |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2686084B1 (fr) * | 1992-01-10 | 1995-12-22 | Bioprojet Soc Civ | Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques. |
| ATE234290T1 (de) * | 1993-11-15 | 2003-03-15 | Schering Corp | Phenylalkyl-imidazole als h3-rezeptor- antagonisten |
| FR2732017B1 (fr) * | 1995-03-21 | 2000-09-22 | Inst Nat Sante Rech Med | Nouveaux derives de l'imidazole antagonistes et/ou agonistes du recepteur h3 de l'histamine, leur preparation et leurs applications therapeutiques |
| EP0920315B1 (en) * | 1996-08-16 | 2005-12-28 | Schering Corporation | Treatment of upper airway allergic responses with a combination of histamine receptor antagonists |
-
1998
- 1998-11-05 CA CA002308586A patent/CA2308586A1/en not_active Abandoned
- 1998-11-05 EP EP98956442A patent/EP1028947B8/en not_active Expired - Lifetime
- 1998-11-05 IL IL13572998A patent/IL135729A0/xx unknown
- 1998-11-05 WO PCT/US1998/023223 patent/WO1999024405A1/en not_active Ceased
- 1998-11-05 KR KR1020007004787A patent/KR20010031724A/ko not_active Withdrawn
- 1998-11-05 HU HU0004292A patent/HUP0004292A3/hu unknown
- 1998-11-05 DE DE69806042T patent/DE69806042T2/de not_active Expired - Fee Related
- 1998-11-05 ES ES98956442T patent/ES2174510T3/es not_active Expired - Lifetime
- 1998-11-05 CN CN98812981A patent/CN1130349C/zh not_active Expired - Fee Related
- 1998-11-05 AT AT98956442T patent/ATE219062T1/de not_active IP Right Cessation
- 1998-11-05 NZ NZ504124A patent/NZ504124A/xx unknown
- 1998-11-05 TW TW087118436A patent/TW421645B/zh not_active IP Right Cessation
- 1998-11-05 AU AU12966/99A patent/AU1296699A/en not_active Abandoned
- 1998-11-05 JP JP2000520419A patent/JP2001522835A/ja not_active Ceased
- 1998-11-06 PE PE1998001070A patent/PE134399A1/es not_active Application Discontinuation
- 1998-11-06 CO CO98065582A patent/CO5011065A1/es unknown
- 1998-11-06 AR ARP980105622A patent/AR016672A1/es unknown
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