ATE219062T1 - Phenylalkyl imidazole derivate als h3 rezeptor liganden - Google Patents
Phenylalkyl imidazole derivate als h3 rezeptor ligandenInfo
- Publication number
- ATE219062T1 ATE219062T1 AT98956442T AT98956442T ATE219062T1 AT E219062 T1 ATE219062 T1 AT E219062T1 AT 98956442 T AT98956442 T AT 98956442T AT 98956442 T AT98956442 T AT 98956442T AT E219062 T1 ATE219062 T1 AT E219062T1
- Authority
- AT
- Austria
- Prior art keywords
- phenylalkyl
- receptor ligands
- imidazole derivatives
- imidazole
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US96634497A | 1997-11-07 | 1997-11-07 | |
US12971198A | 1998-08-05 | 1998-08-05 | |
PCT/US1998/023223 WO1999024405A1 (en) | 1997-11-07 | 1998-11-05 | H3 receptor ligands of the phenyl-alkyl-imidazoles type |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE219062T1 true ATE219062T1 (de) | 2002-06-15 |
Family
ID=26827847
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98956442T ATE219062T1 (de) | 1997-11-07 | 1998-11-05 | Phenylalkyl imidazole derivate als h3 rezeptor liganden |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP1028947B8 (de) |
JP (1) | JP2001522835A (de) |
KR (1) | KR20010031724A (de) |
CN (1) | CN1130349C (de) |
AR (1) | AR016672A1 (de) |
AT (1) | ATE219062T1 (de) |
AU (1) | AU1296699A (de) |
CA (1) | CA2308586A1 (de) |
CO (1) | CO5011065A1 (de) |
DE (1) | DE69806042T2 (de) |
ES (1) | ES2174510T3 (de) |
HK (1) | HK1025968A1 (de) |
HU (1) | HUP0004292A3 (de) |
IL (1) | IL135729A0 (de) |
NZ (1) | NZ504124A (de) |
PE (1) | PE134399A1 (de) |
TW (1) | TW421645B (de) |
WO (1) | WO1999024405A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20020507A1 (es) | 2000-10-17 | 2002-06-25 | Schering Corp | Compuestos no-imidazoles como antagonistas del receptor histamina h3 |
JP4522651B2 (ja) | 2001-03-13 | 2010-08-11 | シェーリング コーポレイション | 新規非イミダゾール化合物 |
PL374758A1 (en) * | 2002-10-24 | 2005-10-31 | Merck Patent Gmbh | Methylene urea derivatives |
WO2006076706A1 (en) | 2005-01-14 | 2006-07-20 | Millennium Pharmaceuticals, Inc. | Cinnamide and hydrocinnamide derivatives with raf-kinase inhibitory activity |
EP1749523A1 (de) * | 2005-07-29 | 2007-02-07 | Neuropharma, S.A. | GSK-3 Inhibitoren |
EP1931665A1 (de) | 2005-09-20 | 2008-06-18 | Schering Corporation | Als histamin-h3-antagonist geeignetes 1-[[1-[(2-amin0-6-methyl-4-pyridinyl)methyl]-4-fluor-4-piperidinyl]carbonyl]-4-[2-(2-pyridinyl)-3h-imidazo[4,5-b]pyridin-3-yl]piperidin |
JP2015530378A (ja) * | 2012-08-29 | 2015-10-15 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | 変形性関節症の処置のためのddr2インヒビター |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2686084B1 (fr) * | 1992-01-10 | 1995-12-22 | Bioprojet Soc Civ | Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques. |
ATE234290T1 (de) * | 1993-11-15 | 2003-03-15 | Schering Corp | Phenylalkyl-imidazole als h3-rezeptor- antagonisten |
FR2732017B1 (fr) * | 1995-03-21 | 2000-09-22 | Inst Nat Sante Rech Med | Nouveaux derives de l'imidazole antagonistes et/ou agonistes du recepteur h3 de l'histamine, leur preparation et leurs applications therapeutiques |
WO1998006394A1 (en) * | 1996-08-16 | 1998-02-19 | Schering Corporation | Treatment of upper airway allergic responses with a combination of histamine receptor antagonists |
-
1998
- 1998-11-05 ES ES98956442T patent/ES2174510T3/es not_active Expired - Lifetime
- 1998-11-05 HU HU0004292A patent/HUP0004292A3/hu unknown
- 1998-11-05 EP EP98956442A patent/EP1028947B8/de not_active Expired - Lifetime
- 1998-11-05 TW TW087118436A patent/TW421645B/zh not_active IP Right Cessation
- 1998-11-05 WO PCT/US1998/023223 patent/WO1999024405A1/en not_active Application Discontinuation
- 1998-11-05 IL IL13572998A patent/IL135729A0/xx unknown
- 1998-11-05 CA CA002308586A patent/CA2308586A1/en not_active Abandoned
- 1998-11-05 JP JP2000520419A patent/JP2001522835A/ja not_active Ceased
- 1998-11-05 NZ NZ504124A patent/NZ504124A/xx unknown
- 1998-11-05 AT AT98956442T patent/ATE219062T1/de not_active IP Right Cessation
- 1998-11-05 DE DE69806042T patent/DE69806042T2/de not_active Expired - Fee Related
- 1998-11-05 AU AU12966/99A patent/AU1296699A/en not_active Abandoned
- 1998-11-05 KR KR1020007004787A patent/KR20010031724A/ko not_active Application Discontinuation
- 1998-11-05 CN CN98812981A patent/CN1130349C/zh not_active Expired - Fee Related
- 1998-11-06 CO CO98065582A patent/CO5011065A1/es unknown
- 1998-11-06 PE PE1998001070A patent/PE134399A1/es not_active Application Discontinuation
- 1998-11-06 AR ARP980105622A patent/AR016672A1/es unknown
-
2000
- 2000-08-25 HK HK00105336A patent/HK1025968A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1028947A1 (de) | 2000-08-23 |
ES2174510T3 (es) | 2002-11-01 |
AU1296699A (en) | 1999-05-31 |
NZ504124A (en) | 2002-10-25 |
AR016672A1 (es) | 2001-07-25 |
EP1028947B8 (de) | 2004-01-28 |
TW421645B (en) | 2001-02-11 |
PE134399A1 (es) | 2000-01-10 |
CN1285822A (zh) | 2001-02-28 |
IL135729A0 (en) | 2001-05-20 |
WO1999024405A1 (en) | 1999-05-20 |
EP1028947B1 (de) | 2002-06-12 |
HUP0004292A3 (en) | 2001-12-28 |
DE69806042T2 (de) | 2003-01-23 |
HK1025968A1 (en) | 2000-12-01 |
JP2001522835A (ja) | 2001-11-20 |
KR20010031724A (ko) | 2001-04-16 |
CA2308586A1 (en) | 1999-05-20 |
CO5011065A1 (es) | 2001-02-28 |
DE69806042D1 (de) | 2002-07-18 |
HUP0004292A2 (hu) | 2001-11-28 |
CN1130349C (zh) | 2003-12-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |