|
US6696475B2
(en)
|
1997-04-22 |
2004-02-24 |
Neurosearch A/S |
Substituted phenyl derivatives, their preparation and use
|
|
BR9814375A
(pt)
*
|
1997-12-22 |
2002-05-21 |
Bayer Ag |
Inibição de raf cinase usando difenil uréias substituìdas simétricas e assimétricas
|
|
OA11665A
(en)
*
|
1998-10-22 |
2004-12-08 |
Neurosearch As |
Substituted phenyl derivatives, their preparation and use.
|
|
WO2003000245A1
(en)
*
|
2001-06-22 |
2003-01-03 |
Poseidon Pharmaceuticals A/S |
Compounds for use in disorders associated with mast cell or basophil activity
|
|
US7087631B2
(en)
*
|
2002-07-18 |
2006-08-08 |
Inotek Pharmaceuticals Corporation |
Aryltetrazole compounds, and compositions thereof
|
|
US7078423B2
(en)
*
|
2002-07-18 |
2006-07-18 |
Inotek Pharmaceuticals Corporation |
5-Aryltetrazole compounds, compositions thereof, and uses therefor
|
|
WO2004012733A2
(en)
*
|
2002-08-01 |
2004-02-12 |
Neurosearch A/S |
Compounds useful for the treatment of diseases responsive to antiangiogenetic therapy
|
|
AU2003258491A1
(en)
*
|
2002-09-05 |
2004-03-29 |
Neurosearch A/S |
Amide derivatives and their use as chloride channel blockers
|
|
MXPA05002493A
(es)
*
|
2002-09-05 |
2005-05-27 |
Neurosearch As |
Derivados de diarilurea y su uso como bloqueadores del canal del cloro.
|
|
AU2003282920A1
(en)
*
|
2002-10-04 |
2004-05-04 |
Bristol-Myers Squibb Company |
Hydantoin derivatives as inhibitors of matrix metalloproteinases and/or tnf-alpha converting enzyme (tace)
|
|
JP2006507329A
(ja)
|
2002-11-21 |
2006-03-02 |
ニューロサーチ、アクティーゼルスカブ |
新規アリールウレイド安息香酸誘導体及びその使用
|
|
US20060229335A1
(en)
*
|
2002-12-24 |
2006-10-12 |
Bradley Teegarden |
Diarylamine and arylheteroarylamine pyrazole derivatives as modulators of 5ht2a
|
|
WO2004111017A1
(en)
*
|
2003-06-17 |
2004-12-23 |
Neurosearch A/S |
Diphenylurea derivatives and their use as chloride channel blockers
|
|
PT1558582E
(pt)
|
2003-07-22 |
2006-05-31 |
Arena Pharm Inc |
Derivados de diaril- e aril-heteroaril-ureia como moduladores do receptor de serotonina 5-ht2a uteis para a profilaxia e tratamento de desordens relacionadas com o mesmo
|
|
US7202363B2
(en)
|
2003-07-24 |
2007-04-10 |
Abbott Laboratories |
Thienopyridine and furopyridine kinase inhibitors
|
|
CA2537746A1
(en)
*
|
2003-09-04 |
2005-03-17 |
Poseidon Pharmaceuticals A/S |
Erg channel openers for the treatment of cardiac arrhythmias
|
|
WO2005023238A1
(en)
*
|
2003-09-04 |
2005-03-17 |
Poseidon Pharmaceuticals A/S |
Erg channel openers for the treatment of hyperexcitability-related neuronal diseases
|
|
WO2005040100A1
(en)
*
|
2003-10-15 |
2005-05-06 |
Bayer Healthcare Ag |
Tetrahydro-naphthalene and urea derivatives
|
|
US20090253908A1
(en)
*
|
2004-03-11 |
2009-10-08 |
Glaxo Group Limited |
Novel m3 muscarinic acetylchoine receptor antagonists
|
|
CA2559038C
(en)
*
|
2004-03-23 |
2013-09-10 |
Arena Pharmaceuticals, Inc. |
Processes for preparing substituted n-aryl-n'-[3-(1h-pyrazol-5-yl) phenyl] ureas and intermediates thereof
|
|
SA05260357B1
(ar)
*
|
2004-11-19 |
2008-09-08 |
ارينا فارماسيتو تيكالز ، أنك |
مشتقات 3_فينيل_بيرازول كمعدلات لمستقبل سيروتينين 5_ht2a مفيدة في علاج الاضطرابات المتعلقه به
|
|
WO2006071940A2
(en)
*
|
2004-12-23 |
2006-07-06 |
Deciphera Pharmaceuticals, Llc |
Enzyme modulators and treatments
|
|
CA2646076C
(en)
|
2006-05-18 |
2015-06-30 |
Arena Pharmaceuticals, Inc. |
Ethers, secondary amines and derivatives thereof as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
|
|
JP5286254B2
(ja)
|
2006-05-18 |
2013-09-11 |
アリーナ ファーマシューティカルズ, インコーポレイテッド |
5−ht2aセロトニンレセプター活性のモジュレーターとして有用なフェニルピラゾールの結晶形態および調製方法
|
|
ES2536762T3
(es)
|
2006-05-18 |
2015-05-28 |
Arena Pharmaceuticals, Inc. |
Aminas primarias y sus derivados como moduladores del receptor de la serotonina 5-HT2A útiles para el tratamiento de trastornos relacionados con este
|
|
TWI415845B
(zh)
*
|
2006-10-03 |
2013-11-21 |
Arena Pharm Inc |
用於治療與5-ht2a血清素受體相關聯病症之作為5-ht2a血清素受體之調節劑的吡唑衍生物
|
|
US7790756B2
(en)
*
|
2006-10-11 |
2010-09-07 |
Deciphera Pharmaceuticals, Llc |
Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases
|
|
US20100137381A1
(en)
|
2007-05-03 |
2010-06-03 |
Neurosearch A/S |
Acetamide derivatives as potassium channel modulators
|
|
WO2009023253A2
(en)
|
2007-08-15 |
2009-02-19 |
Arena Pharmaceuticals Inc. |
IMIDAZO[L,2-α]PYRIDINE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
|
|
WO2009123714A2
(en)
|
2008-04-02 |
2009-10-08 |
Arena Pharmaceuticals, Inc. |
Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
|
|
CN104739829B
(zh)
|
2008-10-28 |
2018-11-06 |
艾尼纳制药公司 |
用于治疗5-ht2a5-羟色胺受体相关障碍的5-ht2a5-羟色胺受体调节剂组合物
|
|
WO2010062321A1
(en)
|
2008-10-28 |
2010-06-03 |
Arena Pharmaceuticals, Inc. |
Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto
|
|
AR074481A1
(es)
|
2008-12-05 |
2011-01-19 |
Abbott Lab |
Derivados de tienopiridina como inhibidores de quinasa
|
|
WO2011075596A1
(en)
|
2009-12-18 |
2011-06-23 |
Arena Pharmaceuticals, Inc. |
Crystalline forms of certain 3-phenyl-pyrazole derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
|
|
US8436179B2
(en)
|
2011-07-20 |
2013-05-07 |
Abbvie Inc. |
Kinase inhibitor with improved solubility profile
|
|
CN103709185A
(zh)
*
|
2013-12-30 |
2014-04-09 |
大连联化医药技术有限公司 |
一种4-(n-甲基甲酰氨)苯基硼酸的制备方法
|
|
WO2016201373A1
(en)
|
2015-06-12 |
2016-12-15 |
Axovant Sciences Ltd. |
Diaryl and arylheteroaryl urea derivatives useful for the prophylaxis and treatment of rem sleep behavior disorder
|
|
WO2017011767A2
(en)
|
2015-07-15 |
2017-01-19 |
Axovant Sciences Ltd. |
Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of hallucinations associated with a neurodegenerative disease
|
|
EP3458052B1
(en)
|
2016-05-17 |
2019-11-06 |
Scandion Oncology A/S |
Combination treatment of cancer
|
|
SG11202000230VA
(en)
|
2017-07-11 |
2020-02-27 |
Vertex Pharma |
Carboxamides as modulators of sodium channels
|
|
US12441703B2
(en)
|
2019-01-10 |
2025-10-14 |
Vertex Pharmaceuticals Incorporated |
Carboxamides as modulators of sodium channels
|
|
WO2020146612A1
(en)
|
2019-01-10 |
2020-07-16 |
Vertex Pharmaceuticals Incorporated |
Esters and carbamates as modulators of sodium channels
|
|
CN117229258B
(zh)
*
|
2022-06-07 |
2024-07-19 |
杭州壹瑞医药科技有限公司 |
N-四唑基芳基脲类衍生物及其制备方法和应用
|