JP2001513821A5 - - Google Patents

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Publication number
JP2001513821A5
JP2001513821A5 JP1998538772A JP53877298A JP2001513821A5 JP 2001513821 A5 JP2001513821 A5 JP 2001513821A5 JP 1998538772 A JP1998538772 A JP 1998538772A JP 53877298 A JP53877298 A JP 53877298A JP 2001513821 A5 JP2001513821 A5 JP 2001513821A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998538772A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001513821A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1998/004254 external-priority patent/WO1998039303A1/en
Publication of JP2001513821A publication Critical patent/JP2001513821A/ja
Publication of JP2001513821A5 publication Critical patent/JP2001513821A5/ja
Ceased legal-status Critical Current

Links

JP53877298A 1997-03-03 1998-03-03 炎症性疾患の治療に有用な小分子 Ceased JP2001513821A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4001197P 1997-03-03 1997-03-03
US60/040,011 1997-03-03
PCT/US1998/004254 WO1998039303A1 (en) 1997-03-03 1998-03-03 Small molecules useful in the treatment of inflammatory disease

Publications (2)

Publication Number Publication Date
JP2001513821A JP2001513821A (ja) 2001-09-04
JP2001513821A5 true JP2001513821A5 (https=) 2005-11-10

Family

ID=21908586

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53877298A Ceased JP2001513821A (ja) 1997-03-03 1998-03-03 炎症性疾患の治療に有用な小分子

Country Status (22)

Country Link
EP (1) EP0966447B1 (https=)
JP (1) JP2001513821A (https=)
KR (1) KR20000075893A (https=)
CN (1) CN1249748A (https=)
AT (1) ATE233738T1 (https=)
AU (1) AU6541898A (https=)
BG (1) BG103711A (https=)
BR (1) BR9811260A (https=)
CA (1) CA2278547A1 (https=)
DE (1) DE69811867T2 (https=)
DK (1) DK0966447T3 (https=)
EA (1) EA199900758A1 (https=)
EE (1) EE9900481A (https=)
ES (1) ES2191286T3 (https=)
HU (1) HUP0002347A2 (https=)
IL (1) IL130931A0 (https=)
NO (1) NO994256L (https=)
PL (1) PL336580A1 (https=)
PT (1) PT966447E (https=)
SK (1) SK117499A3 (https=)
TR (1) TR199902124T2 (https=)
WO (1) WO1998039303A1 (https=)

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US6878700B1 (en) 1998-12-29 2005-04-12 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds
US6867203B2 (en) 1998-12-29 2005-03-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds
EP1399155B1 (en) 1999-07-21 2008-05-28 Boehringer Ingelheim Pharmaceuticals Inc. Small molecules useful in the treatment of inflammatory disease
US6353013B1 (en) 1999-07-21 2002-03-05 Boehringer Ingelheim Pharmaceuticals, Inc. Small molecules useful in the treatment of inflammatory disease
US6492408B1 (en) * 1999-07-21 2002-12-10 Boehringer Ingelheim Pharmaceuticals, Inc. Small molecules useful in the treatment of inflammatory disease
US6365615B1 (en) 1999-07-21 2002-04-02 Boehringer Ingelheim Pharmaceuticals, Inc. Small molecules useful in the treatment of inflammatory disease
US6897225B1 (en) 1999-10-20 2005-05-24 Tanabe Seiyaku Co., Ltd. Inhibitors of αLβ2 mediated cell adhesion
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US7001911B2 (en) 2000-06-28 2006-02-21 Bristol-Myers Squibb Company Fused cyclic modulators of nuclear hormone receptor function
US20040077605A1 (en) 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
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US6521619B2 (en) 2000-06-29 2003-02-18 Icos Corporation Aryl phenylcyclopropyl sulfide derivatives and their use as cell adhesion inhibiting anti-inflammatory and immune suppressive agents
US6846643B2 (en) * 2000-08-14 2005-01-25 Boehringer Ingelheim Pharmaceuticals, Inc. Methods and molecules useful for identifying molecules that bind LFA-1 and for determining receptor occupancy
US6953679B2 (en) 2000-09-19 2005-10-11 Bristol-Myers Squibb Company Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof
WO2002044181A1 (en) * 2000-12-01 2002-06-06 Bristol-Myers Squibb Company Hydantoin compounds useful as anti-inflammatory agents
US20030008848A1 (en) * 2000-12-19 2003-01-09 Fleck Roman Wolfgang Small molecules useful in the treatment of inflammatory disease
US7544812B2 (en) * 2001-11-30 2009-06-09 Eli Lilly And Company Peroxisome proliferator activated receptor agonists
DE60228330D1 (de) 2001-12-19 2008-09-25 Bristol Myers Squibb Co Kondensierte heterocyclische verbindungen und deren analoga; modulatoren der funktion von nukleären hormonrezeptoren
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MY139983A (en) 2002-03-12 2009-11-30 Janssen Alzheimer Immunotherap Humanized antibodies that recognize beta amyloid peptide
KR101011373B1 (ko) 2002-07-11 2011-01-28 비큐론 파마슈티컬스 인코포레이티드 항균작용을 갖는 n-히드록시아미드 유도체
WO2004032861A2 (en) 2002-10-11 2004-04-22 Bristol-Myers Squibb Company Hexahydro-benzimidazolone compounds useful as anti-inflammatory agents
US6852748B1 (en) 2002-10-30 2005-02-08 Boehringer Ingelheim Pharmaceuticals, Inc. Derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonyl]-pyrrolidine-2-carboxylic acid amide
US6844360B2 (en) 2002-10-30 2005-01-18 Boehringer Ingelheim Pharmaceuticals, Inc. Derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonylamino]-propionamide
FR2850652B1 (fr) * 2003-01-31 2008-05-30 Aventis Pharma Sa Nouveaux derives d'uree cyclique, leur preparation et leur utilisation pharmaceutique comme inhibiteurs de kinases
US7354933B2 (en) 2003-01-31 2008-04-08 Aventis Pharma Sa Cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
SI2384753T1 (sl) 2003-08-29 2016-06-30 The Brigham And Women's Hospital, Inc. Hidantoinski derivati kot inhibitorji celične nekroze
US7199125B2 (en) 2003-10-02 2007-04-03 Bristol-Myers Squibb Company Spiro-cyclic compounds useful as anti-inflammatory agents
DOP2005000123A (es) * 2004-07-02 2011-07-15 Merck Sharp & Dohme Inhibidores de cetp
ATE478864T1 (de) * 2004-07-16 2010-09-15 Schering Corp Hydantoinderivate zur behandlung von entzündlichen erkrankungen
EP1621535A1 (en) * 2004-07-27 2006-02-01 Aventis Pharma S.A. Substituted cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
KR20070047798A (ko) * 2004-07-27 2007-05-07 베링거 인겔하임 인터내셔날 게엠베하 6,7-디하이드로-5H-이미다조[1,2-a]이미다졸-3-설폰산아미드의 합성
US7375237B2 (en) 2004-08-18 2008-05-20 Bristol-Myers Squibb Company Pyrrolizine compounds useful as anti-inflammatory agents
TW200616634A (en) 2004-10-01 2006-06-01 Bristol Myers Squibb Co Crystalline forms and process for preparing spiro-hydantoin compounds
JPWO2006051937A1 (ja) * 2004-11-15 2008-05-29 塩野義製薬株式会社 ヘテロ5員環誘導体
US7186727B2 (en) 2004-12-14 2007-03-06 Bristol-Myers Squibb Company Pyridyl-substituted spiro-hydantoin compounds and use thereof
WO2006066089A1 (en) 2004-12-15 2006-06-22 Neuralab Limited Humanized amyloid beta antibodies for use in improving cognition
CN101166743A (zh) 2005-05-19 2008-04-23 贝林格尔·英格海姆国际有限公司 6,7-二氢-5H-咪唑并[1,2-α]咪唑-3-磺酸的衍生物
KR20080066949A (ko) * 2005-10-11 2008-07-17 인터뮨, 인크. 바이러스 복제 억제제
US8784810B2 (en) 2006-04-18 2014-07-22 Janssen Alzheimer Immunotherapy Treatment of amyloidogenic diseases
US8168667B2 (en) 2006-05-31 2012-05-01 Galapagos Nv Imidazolidine derivatives, uses therefor, preparation thereof and compositions comprising such
US8003097B2 (en) 2007-04-18 2011-08-23 Janssen Alzheimer Immunotherapy Treatment of cerebral amyloid angiopathy
PT2182983E (pt) 2007-07-27 2014-09-01 Janssen Alzheimer Immunotherap Tratamento de doenças amiloidogénicas com anticorpos anti-abeta humanizados
JO3076B1 (ar) 2007-10-17 2017-03-15 Janssen Alzheimer Immunotherap نظم العلاج المناعي المعتمد على حالة apoe
MY151004A (en) 2007-11-29 2014-03-31 Boehringer Ingelheim Int Derivatives of 6,7-dihydro-5h-imidazo[1,2-?]imidazole-3-carboxylic acid amides
GB2463514C (en) * 2008-09-11 2018-09-26 Galapagos Nv Imidazolidine compounds and uses therefor
US9067981B1 (en) 2008-10-30 2015-06-30 Janssen Sciences Ireland Uc Hybrid amyloid-beta antibodies
CA2772760A1 (en) 2008-12-23 2010-07-01 President And Fellows Of Harvard College Small molecule inhibitors of necroptosis
ITBO20090078A1 (it) * 2009-02-13 2010-08-14 Consiglio Nazionale Ricerche Composti per il trattamento del tumore alla prostata e procedimenti per la loro sintesi
WO2010141330A1 (en) 2009-06-02 2010-12-09 Boehringer Ingelheim International Gmbh DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES
EA019990B1 (ru) 2009-06-02 2014-07-30 Бёрингер Ингельхайм Интернациональ Гмбх ПРОИЗВОДНЫЕ АМИДОВ 6,7-ДИГИДРО-5H-ИМИДАЗО[1,2-a]ИМИДАЗОЛ-3-КАРБОНОВОЙ КИСЛОТЫ
CN102731525A (zh) * 2011-04-08 2012-10-17 上海艾力斯医药科技有限公司 苯并吗啉衍生物
US9725452B2 (en) 2013-03-15 2017-08-08 Presidents And Fellows Of Harvard College Substituted indoles and pyrroles as RIP kinase inhibitors
US10077238B2 (en) * 2014-06-12 2018-09-18 Allocyte Pharmaceuticals Ag Small molecule LFA-1 inhibitors
AR102942A1 (es) 2014-12-11 2017-04-05 Bayer Cropscience Ag Derivados de arilsulfuro y arilsulfóxido de cinco miembros c-n-conectados, como plaguicidas
EP3229807A4 (en) 2014-12-11 2018-10-17 President and Fellows of Harvard College Inhibitors of cellular necrosis and related methods
CN113024513A (zh) * 2021-03-22 2021-06-25 中国药科大学 新型雄激素受体降解剂、制备方法和医药用途
WO2026045350A1 (en) * 2024-09-02 2026-03-05 Innocare Pharma Inc. Heterocyclic vav1 degraders

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FR2015493A1 (https=) * 1968-08-12 1970-04-30 Sumitomo Chemical Co
DK123717B (da) * 1968-11-25 1972-07-24 Sumitomo Chemical Co 3-(3',5'-Dihalogenphenyl)-imidazolidin-2,4-dionderivater med mirobicid virkning.
DE3382406D1 (de) * 1982-04-08 1991-10-17 Shell Int Research Neue hydantoine, ihre herstellung und verwendung.
IE62214B1 (en) * 1988-05-25 1995-01-11 Warner Lambert Co Arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflammatory agents
EP0545478A1 (en) * 1991-12-03 1993-06-09 MERCK SHARP & DOHME LTD. Heterocyclic compounds as tachykinin antagonists
TW521073B (en) * 1994-01-05 2003-02-21 Hoechst Marion Roussel Inc New optionally substituted phenylimidazolidines, their preparation process, their use as anti-androgenic agent and the pharmaceutical compositions containing them

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