JP2001509361A5 - - Google Patents
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- Publication number
- JP2001509361A5 JP2001509361A5 JP2000500926A JP2000500926A JP2001509361A5 JP 2001509361 A5 JP2001509361 A5 JP 2001509361A5 JP 2000500926 A JP2000500926 A JP 2000500926A JP 2000500926 A JP2000500926 A JP 2000500926A JP 2001509361 A5 JP2001509361 A5 JP 2001509361A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- differentiated
- chimeric
- unit
- developing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 description 52
- 210000004027 cell Anatomy 0.000 description 15
- 210000003855 cell nucleus Anatomy 0.000 description 13
- 210000004962 mammalian cell Anatomy 0.000 description 9
- 210000001161 mammalian embryo Anatomy 0.000 description 9
- 210000003754 fetus Anatomy 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 4
- 210000000287 oocyte Anatomy 0.000 description 4
- 230000009261 transgenic effect Effects 0.000 description 4
- 241000124008 Mammalia Species 0.000 description 2
- BVIAOQMSVZHOJM-UHFFFAOYSA-N N(6),N(6)-dimethyladenine Chemical compound CN(C)C1=NC=NC2=C1N=CN2 BVIAOQMSVZHOJM-UHFFFAOYSA-N 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 230000004913 activation Effects 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 241000283690 Bos taurus Species 0.000 description 1
- 241000283707 Capra Species 0.000 description 1
- 241000283086 Equidae Species 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 241000282887 Suidae Species 0.000 description 1
- 238000010367 cloning Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 238000004520 electroporation Methods 0.000 description 1
- 210000002308 embryonic cell Anatomy 0.000 description 1
- 230000007159 enucleation Effects 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 210000002443 helper t lymphocyte Anatomy 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000000520 microinjection Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88828397A | 1997-07-03 | 1997-07-03 | |
| US08/888,283 | 1997-07-03 | ||
| PCT/US1998/012800 WO1999001163A1 (en) | 1997-07-03 | 1998-06-24 | Cloning using donor nuclei from non-serum starved, differentiated cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001509361A JP2001509361A (ja) | 2001-07-24 |
| JP2001509361A5 true JP2001509361A5 (enExample) | 2006-01-05 |
Family
ID=25392916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000500926A Pending JP2001509361A (ja) | 1997-07-03 | 1998-06-24 | 分化した無血清飢餓細胞からの供与核を用いるクローニング |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1017422A4 (enExample) |
| JP (1) | JP2001509361A (enExample) |
| CN (2) | CN101003800A (enExample) |
| AU (1) | AU8154398A (enExample) |
| BR (1) | BR9811657A (enExample) |
| CA (1) | CA2294916A1 (enExample) |
| IL (1) | IL133786A0 (enExample) |
| NZ (1) | NZ502129A (enExample) |
| WO (1) | WO1999001163A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6235969B1 (en) * | 1997-01-10 | 2001-05-22 | University Of Massachusetts | Cloning pigs using donor nuclei from non-quiescent differentiated cells |
| AU739902B2 (en) * | 1998-01-16 | 2001-10-25 | Agrobiogen Gmbh | Efficient nuclear transfer using fetal fibroblasts |
| US6331659B1 (en) | 1998-01-21 | 2001-12-18 | University Of Hawaii | Cumulus cells as nuclear donors |
| JP2002511234A (ja) * | 1998-03-16 | 2002-04-16 | リレグ ピーティーワイ リミテッド | ブタの核移植 |
| AUPP294898A0 (en) * | 1998-04-15 | 1998-05-07 | Monash University | Method of nuclear transfer |
| WO2000025578A2 (en) * | 1999-04-26 | 2000-05-11 | Trustees Of Tufts College | Methods for cloning animals |
| EP1818397A1 (en) * | 1998-11-02 | 2007-08-15 | Trustees Of Tufts College | Methods for cloning animals |
| EP1375654A3 (en) * | 1998-11-02 | 2008-01-16 | GTC Biotherapeutics, Inc. | Transgenic and cloned mammals |
| US6781030B1 (en) | 1998-11-02 | 2004-08-24 | Trustee Of Tufts College, Ballou Hall | Methods for cloning mammals using telophase oocytes |
| AU780754B2 (en) | 1999-03-04 | 2005-04-14 | Revivicor Inc | Genetic modification of somatic cells and uses thereof |
| US6590139B1 (en) * | 1999-06-30 | 2003-07-08 | Woo-Suk Hwang | Method for producing cloned cows |
| JP2003503044A (ja) * | 1999-06-30 | 2003-01-28 | ワン，ウー−サク | 種間核移植技術を用いたヒトクローン胚の作製方法 |
| WO2001000794A1 (en) * | 1999-06-30 | 2001-01-04 | Hwang, Woo-Suk | Method for producing cloned tigers by employing inter-species nuclear transplantation technique |
| BR0014864A (pt) * | 1999-10-15 | 2002-11-19 | Advanced Cell Tech Inc | Métodos de produzir células progenitoras diferenciadas e células tronco embriÈnicas defeituosas em linhagem |
| AU2000250770A1 (en) * | 2000-06-08 | 2001-12-17 | Trostner, Jens | Method for the genetic reconstruction of human organs |
| CA2634294A1 (en) | 2000-08-03 | 2002-02-14 | Therapeutic Human Polyclonals, Inc. | Production of humanized antibodies in transgenic animals |
| FR2814642B1 (fr) | 2000-10-03 | 2005-07-01 | Ass Pour Le Dev De La Rech En | Souris transgenique pour la recombinaison ciblee mediee par la cre-er modifiee |
| US20020168763A1 (en) * | 2000-11-30 | 2002-11-14 | Yan Wen Liang | Isolated homozygous stem cells, differentiated cells derived therefrom, and materials and methods for making and using same |
| AU2002232858B2 (en) * | 2000-12-22 | 2007-01-11 | Sab, Llc | Methods for cloning mammals using reprogrammed donor chromatin or donor cells |
| EP1217071B1 (en) | 2000-12-22 | 2010-04-28 | Institut National De La Recherche Agronomique | Position-independent and tissue specific expression of a transgene in milk of transgenic animals |
| JP4381139B2 (ja) | 2001-08-13 | 2009-12-09 | エンブレクス，インコーポレイテッド | 鳥類の卵の処理方法 |
| AU2003230725A1 (en) * | 2002-04-01 | 2003-10-20 | Gtc Biotherapeutics, Inc. | A method for selecting cell lines to be used for nuclear transfer in mammalian species |
| US7612250B2 (en) | 2002-07-29 | 2009-11-03 | Trustees Of Tufts College | Nuclear transfer embryo formation method |
| RU2308281C1 (ru) * | 2006-04-05 | 2007-10-20 | ГУ Научно-исследовательский институт фармакологии Томского научного центра Сибирского отделения Российской академии медицинских наук (ГУ НИИ фармакологии ТНЦ СО РАМН) | Способ клонирования in vitro регионарных стволовых клеток поджелудочной железы |
| WO2008027986A2 (en) | 2006-09-01 | 2008-03-06 | Therapeutic Human Polyclonals, Inc. | Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals |
| EP2267153A1 (en) | 2009-05-26 | 2010-12-29 | Université Claude Bernard Lyon 1 | Identification of netrin-1 receptor unc5c gene mutation in solid cancers |
| WO2013010045A1 (en) | 2011-07-12 | 2013-01-17 | Biotime Inc. | Novel methods and formulations for orthopedic cell therapy |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0739412B1 (en) * | 1993-12-23 | 2002-02-27 | Infigen, Inc. | ungulate EMBRYONIC STEM CELLS AS NUCLEAR DONORS AND NUCLEAR TRANSFER TECHNIQUES TO PRODUCE CHIMERIC AND TRANSGENIC ANIMALS |
| GB9517780D0 (en) * | 1995-08-31 | 1995-11-01 | Roslin Inst Edinburgh | Biological manipulation |
| GB9517779D0 (en) | 1995-08-31 | 1995-11-01 | Roslin Inst Edinburgh | Biological manipulation |
| US5945577A (en) | 1997-01-10 | 1999-08-31 | University Of Massachusetts As Represented By Its Amherst Campus | Cloning using donor nuclei from proliferating somatic cells |
| AU739902B2 (en) * | 1998-01-16 | 2001-10-25 | Agrobiogen Gmbh | Efficient nuclear transfer using fetal fibroblasts |
-
1998
- 1998-06-24 IL IL13378698A patent/IL133786A0/xx unknown
- 1998-06-24 WO PCT/US1998/012800 patent/WO1999001163A1/en not_active Ceased
- 1998-06-24 AU AU81543/98A patent/AU8154398A/en not_active Abandoned
- 1998-06-24 CN CNA2007100081920A patent/CN101003800A/zh active Pending
- 1998-06-24 BR BR9811657-6A patent/BR9811657A/pt not_active Application Discontinuation
- 1998-06-24 JP JP2000500926A patent/JP2001509361A/ja active Pending
- 1998-06-24 EP EP19980931400 patent/EP1017422A4/en not_active Withdrawn
- 1998-06-24 NZ NZ502129A patent/NZ502129A/en unknown
- 1998-06-24 CA CA002294916A patent/CA2294916A1/en not_active Abandoned
- 1998-06-24 CN CN98807691A patent/CN1265599A/zh active Pending
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