BR0014864A - Métodos de produzir células progenitoras diferenciadas e células tronco embriÈnicas defeituosas em linhagem - Google Patents
Métodos de produzir células progenitoras diferenciadas e células tronco embriÈnicas defeituosas em linhagemInfo
- Publication number
- BR0014864A BR0014864A BR0014864-4A BR0014864A BR0014864A BR 0014864 A BR0014864 A BR 0014864A BR 0014864 A BR0014864 A BR 0014864A BR 0014864 A BR0014864 A BR 0014864A
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- Prior art keywords
- cells
- progenitor cells
- differentiated progenitor
- methods
- embryonic stem
- Prior art date
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Neurosurgery (AREA)
- Developmental Biology & Embryology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Virology (AREA)
- Psychology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
Abstract
"MéTODOS DE PRODUZIR CéLULAS PROGENITORAS DIFERENCIADAS E CéLULAS TRONCO EMBRIÈNICAS DEFEITUOSAS EM LINHAGEM". Um método aperfeiçoado de produzir células progenitoras aperfeiçoadas compreendendo obtendo células de massa de célula interna de um blastócisto e induzindo diferenciação das células de massa de célula interna para produzir células progenitoras diferenciadas. As células progenitoras diferenciadas podem ser transfectadas tais que exista além disso, anulação ou alteração de um gene desejado. As células progenitoras diferenciadas são úteis em terapia de célula e como uma fonte I de células para a produção de tecidos e orgãos para transplantação. Também fornecido é um método para produzir uma célula de tronco embriónica humana defeituosa em linhagem.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15955099P | 1999-10-15 | 1999-10-15 | |
PCT/US2000/028285 WO2001029206A1 (en) | 1999-10-15 | 2000-10-13 | Methods of producing differentiated progenitor cells and lineage-defective embryonic stem cells |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0014864A true BR0014864A (pt) | 2002-11-19 |
Family
ID=22573023
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0014864-4A BR0014864A (pt) | 1999-10-15 | 2000-10-13 | Métodos de produzir células progenitoras diferenciadas e células tronco embriÈnicas defeituosas em linhagem |
Country Status (11)
Country | Link |
---|---|
US (3) | US20050265976A1 (pt) |
EP (1) | EP1226239A4 (pt) |
JP (1) | JP2003512052A (pt) |
CN (1) | CN1413250A (pt) |
AU (1) | AU782385B2 (pt) |
BR (1) | BR0014864A (pt) |
CA (1) | CA2388497A1 (pt) |
IL (2) | IL149043A0 (pt) |
MX (1) | MXPA02003733A (pt) |
NZ (1) | NZ518191A (pt) |
WO (1) | WO2001029206A1 (pt) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
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US10638734B2 (en) | 2004-01-05 | 2020-05-05 | Abt Holding Company | Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof |
US8252280B1 (en) | 1999-08-05 | 2012-08-28 | Regents Of The University Of Minnesota | MAPC generation of muscle |
US7015037B1 (en) | 1999-08-05 | 2006-03-21 | Regents Of The University Of Minnesota | Multiponent adult stem cells and methods for isolation |
EP1214403A4 (en) * | 1999-09-07 | 2005-03-09 | Advanced Cell Tech Inc | METHOD OF GENERATING IMMUNOCOMPATIBLE CELLS AND TISSUE USING NUCLEAR TRANSFER TECHNIQUES |
US20020142397A1 (en) | 2000-12-22 | 2002-10-03 | Philippe Collas | Methods for altering cell fate |
CA2433419A1 (en) | 2001-01-02 | 2002-07-25 | Stemron, Inc. | A method for producing a population of homozygous stem cells having a pre-selected immunotype and/or genotype, cells suitable for transplant derived therefrom, and materials and methods using same |
EP1367899A4 (en) | 2001-02-14 | 2004-07-28 | Leo T Furcht | TOTIPOTENT ADULT STEM CELLS, SOURCES OF SUCH CELLS, METHODS FOR OBTAINING AND MAINTAINING SAME, METHODS FOR DIFFERENTIATING THESE CELLS, METHODS OF USING SAME, AND CELLS DERIVED FROM THE ABOVE-MENTIONED CELLS |
CA2453068C (en) * | 2001-07-06 | 2018-02-20 | Geron Corporation | Mesenchymal cells and osteoblasts from human embryonic stem cell |
AU2002246132A1 (en) * | 2002-03-13 | 2003-09-22 | Fundacion Ivi Para El Estudio De La Reproduccion Humana (Fivier) | Method of producing cell lines |
WO2004061092A1 (ja) | 2002-12-27 | 2004-07-22 | Mitsubishi Heavy Industries, Ltd. | 多能性幹細胞の培養方法とそのための培養装置 |
US7838727B2 (en) | 2004-11-04 | 2010-11-23 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells |
US7893315B2 (en) | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
WO2006112390A1 (ja) * | 2005-04-14 | 2006-10-26 | Japan As Represented By General Director Of Agency Of National Cardiovascular Center | 脂肪由来前駆細胞およびその利用 |
CA2659945C (en) | 2005-08-03 | 2014-12-16 | Advanced Cell Technology, Inc. | Improved methods of reprogramming animal somatic cells |
KR20170102040A (ko) | 2006-04-14 | 2017-09-06 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 혈관 콜로니 형성 세포 |
KR20150142061A (ko) | 2006-05-03 | 2015-12-21 | 오카타 세라퓨틱스, 인크. | 배아 줄기 세포 및 배-유도 세포의 유도 |
EP2087101A2 (en) | 2006-11-24 | 2009-08-12 | Regents of the University of Minnesota | Endodermal progenitor cells |
EP3190178A1 (en) | 2007-02-23 | 2017-07-12 | Astellas Institute for Regenerative Medicine | Highly efficient methods for reprogramming differentiated cells and for generating animals and embryonic stem cells from reprogrammed cells |
CN102083963A (zh) | 2008-05-06 | 2011-06-01 | 先进细胞技术公司 | 血管瘤集落形成细胞和非移植血管瘤细胞 |
CN104328087A (zh) | 2008-05-06 | 2015-02-04 | 先进细胞技术公司 | 用于制备衍生自多能干细胞的去核类红细胞的方法 |
US10386360B2 (en) | 2009-03-13 | 2019-08-20 | University Of Central Florida Research Foundation, Inc. | Bio-microelectromechanical system transducer and associated methods |
US8815584B1 (en) | 2009-04-23 | 2014-08-26 | University Of Central Florida Research Foundation, Inc. | Method of co-culturing mammalian muscle cells and motoneurons |
US9404140B1 (en) | 2009-11-03 | 2016-08-02 | The University Of Central Florida Research Foundation, Inc. | Patterned cardiomyocyte culture on microelectrode array |
EP2585171B1 (en) | 2010-04-23 | 2018-12-26 | University Of Central Florida Research Foundation, Inc. | Formation of neuromuscular junctions in a defined system |
JP2010193910A (ja) * | 2010-06-14 | 2010-09-09 | Mitsubishi Heavy Ind Ltd | 多能性幹細胞の培養方法、多能性幹細胞の培養システム、及び多能性幹細胞培養装置 |
EP2606608B1 (de) | 2010-08-20 | 2019-12-18 | Hirschmann Automation and Control GmbH | Erweiterung für das simple network management protocol (snmp) um informationen über den status von set-pdus zu ermitteln |
CN105349492B (zh) * | 2011-05-18 | 2019-04-16 | 加利福尼亚大学董事会 | 用于治疗视网膜疾病的组合物及方法 |
WO2013010045A1 (en) | 2011-07-12 | 2013-01-17 | Biotime Inc. | Novel methods and formulations for orthopedic cell therapy |
WO2014100779A1 (en) | 2012-12-21 | 2014-06-26 | Advanced Cell Technology, Inc. | Methods ofr production of platelets from pluripotent stem cells and compositions thereof |
US20150369791A1 (en) * | 2013-01-30 | 2015-12-24 | University Of Central Florida Research Foundation, Inc. | Devices and systems for mimicking heart function |
US10935541B2 (en) | 2014-08-07 | 2021-03-02 | University Of Central Florida Research Foundation, Inc. | Devices and methods comprising neuromuscular junctions |
WO2017048193A1 (en) * | 2015-09-15 | 2017-03-23 | Agency For Science, Technology And Research (A*Star) | Derivation of liver organoids from human pluripotent stem cells |
MX2018014016A (es) | 2016-05-16 | 2019-08-01 | Intarcia Therapeutics Inc | Polipéptidos selectivos del receptor de glucagón y métodos para utilizarlos. |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
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EP1298202B1 (en) | 1992-10-28 | 2010-10-06 | NeuroSpheres Holdings Ltd. | Biological factors and neural stem cells |
US5523226A (en) * | 1993-05-14 | 1996-06-04 | Biotechnology Research And Development Corp. | Transgenic swine compositions and methods |
US5532156A (en) * | 1993-10-08 | 1996-07-02 | The United States Of America As Represented By The Secretary Of Agriculture | Hepatocyte cell line derived from the epiblast of pig blastocysts |
US5843780A (en) * | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
IL128348A (en) * | 1996-08-19 | 2008-08-07 | Univ Massachusetts | Method of producing embryonic or stem like cell lines by transplantation of cell nuclei from animal or mammal, such cells and uses thereof |
US5945577A (en) * | 1997-01-10 | 1999-08-31 | University Of Massachusetts As Represented By Its Amherst Campus | Cloning using donor nuclei from proliferating somatic cells |
CN101003800A (zh) * | 1997-07-03 | 2007-07-25 | 马萨诸塞大学 | 使用来自无血清饥饿的分化细胞的供体细胞核进行克隆 |
ES2285785T3 (es) * | 1997-09-29 | 2007-11-16 | Point Therapeutics, Inc. | Estimulacion de celulas hematopoyeticas in vitro. |
JP2002505100A (ja) * | 1998-03-02 | 2002-02-19 | ユニヴァーシティー オヴ マサチューセッツ アパブリック インスティテューション オヴ ハイアー エデュケイション オヴ ザ コモンウェルス オヴ マサチューセッツ リプレゼンティド バイイッツ アム | 種間核移植によって作製された胚性または幹細胞様細胞株 |
BR0013999A (pt) * | 1999-09-14 | 2002-05-21 | Univ Massachusetts Public Inst | Linhagens de célula embriÈnicas ou semelhantes a células tronco produzidas por transplante nuclear de espécies cruzadas e métodos para melhorar o desenvolvimento embriÈnico por alteração genética de células doadoras ou por condições de cultura de tecido |
US6576464B2 (en) * | 2000-11-27 | 2003-06-10 | Geron Corporation | Methods for providing differentiated stem cells |
US7947499B2 (en) * | 2002-11-29 | 2011-05-24 | Technion Research & Development Foundation Ltd. | Method of dynamically culturing embryonic stem cells |
-
2000
- 2000-10-13 AU AU12000/01A patent/AU782385B2/en not_active Ceased
- 2000-10-13 CA CA002388497A patent/CA2388497A1/en not_active Abandoned
- 2000-10-13 IL IL14904300A patent/IL149043A0/xx unknown
- 2000-10-13 NZ NZ518191A patent/NZ518191A/en not_active IP Right Cessation
- 2000-10-13 WO PCT/US2000/028285 patent/WO2001029206A1/en active IP Right Grant
- 2000-10-13 EP EP00973497A patent/EP1226239A4/en not_active Ceased
- 2000-10-13 MX MXPA02003733A patent/MXPA02003733A/es unknown
- 2000-10-13 BR BR0014864-4A patent/BR0014864A/pt not_active Application Discontinuation
- 2000-10-13 CN CN00817477A patent/CN1413250A/zh active Pending
- 2000-10-13 JP JP2001532190A patent/JP2003512052A/ja active Pending
-
2002
- 2002-04-09 IL IL149043A patent/IL149043A/en unknown
-
2004
- 2004-12-29 US US11/025,893 patent/US20050265976A1/en not_active Abandoned
-
2008
- 2008-05-16 US US12/152,779 patent/US8753884B2/en not_active Expired - Fee Related
-
2014
- 2014-05-07 US US14/272,365 patent/US20140248700A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN1413250A (zh) | 2003-04-23 |
US20090104697A1 (en) | 2009-04-23 |
NZ518191A (en) | 2004-01-30 |
AU1200001A (en) | 2001-04-30 |
WO2001029206A1 (en) | 2001-04-26 |
JP2003512052A (ja) | 2003-04-02 |
EP1226239A1 (en) | 2002-07-31 |
US8753884B2 (en) | 2014-06-17 |
MXPA02003733A (es) | 2003-10-14 |
IL149043A (en) | 2010-11-30 |
CA2388497A1 (en) | 2001-04-26 |
EP1226239A4 (en) | 2003-02-12 |
AU782385B2 (en) | 2005-07-21 |
US20140248700A1 (en) | 2014-09-04 |
IL149043A0 (en) | 2002-11-10 |
US20050265976A1 (en) | 2005-12-01 |
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