BR0014864A - Métodos de produzir células progenitoras diferenciadas e células tronco embriÈnicas defeituosas em linhagem - Google Patents
Métodos de produzir células progenitoras diferenciadas e células tronco embriÈnicas defeituosas em linhagemInfo
- Publication number
- BR0014864A BR0014864A BR0014864-4A BR0014864A BR0014864A BR 0014864 A BR0014864 A BR 0014864A BR 0014864 A BR0014864 A BR 0014864A BR 0014864 A BR0014864 A BR 0014864A
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- Prior art keywords
- cells
- progenitor cells
- differentiated progenitor
- methods
- embryonic stem
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/00—Drugs for disorders of the respiratory system
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/18—Antivirals for RNA viruses for HIV
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
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- Neurology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Developmental Biology & Embryology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychology (AREA)
- Virology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
Abstract
"MéTODOS DE PRODUZIR CéLULAS PROGENITORAS DIFERENCIADAS E CéLULAS TRONCO EMBRIÈNICAS DEFEITUOSAS EM LINHAGEM". Um método aperfeiçoado de produzir células progenitoras aperfeiçoadas compreendendo obtendo células de massa de célula interna de um blastócisto e induzindo diferenciação das células de massa de célula interna para produzir células progenitoras diferenciadas. As células progenitoras diferenciadas podem ser transfectadas tais que exista além disso, anulação ou alteração de um gene desejado. As células progenitoras diferenciadas são úteis em terapia de célula e como uma fonte I de células para a produção de tecidos e orgãos para transplantação. Também fornecido é um método para produzir uma célula de tronco embriónica humana defeituosa em linhagem.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15955099P | 1999-10-15 | 1999-10-15 | |
PCT/US2000/028285 WO2001029206A1 (en) | 1999-10-15 | 2000-10-13 | Methods of producing differentiated progenitor cells and lineage-defective embryonic stem cells |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0014864A true BR0014864A (pt) | 2002-11-19 |
Family
ID=22573023
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0014864-4A BR0014864A (pt) | 1999-10-15 | 2000-10-13 | Métodos de produzir células progenitoras diferenciadas e células tronco embriÈnicas defeituosas em linhagem |
Country Status (11)
Country | Link |
---|---|
US (3) | US20050265976A1 (pt) |
EP (1) | EP1226239A4 (pt) |
JP (1) | JP2003512052A (pt) |
CN (1) | CN1413250A (pt) |
AU (1) | AU782385B2 (pt) |
BR (1) | BR0014864A (pt) |
CA (1) | CA2388497A1 (pt) |
IL (2) | IL149043A0 (pt) |
MX (1) | MXPA02003733A (pt) |
NZ (1) | NZ518191A (pt) |
WO (1) | WO2001029206A1 (pt) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2007019398A1 (en) | 2005-08-03 | 2007-02-15 | Advanced Cell Technology, Inc. | Improved methods of reprogramming animal somatic cells |
US10638734B2 (en) | 2004-01-05 | 2020-05-05 | Abt Holding Company | Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof |
US7015037B1 (en) | 1999-08-05 | 2006-03-21 | Regents Of The University Of Minnesota | Multiponent adult stem cells and methods for isolation |
US8252280B1 (en) | 1999-08-05 | 2012-08-28 | Regents Of The University Of Minnesota | MAPC generation of muscle |
BR0011905A (pt) * | 1999-09-07 | 2003-07-08 | Advanced Cell Tech Inc | Processo para gerar células e tecidos imunocompatìveis usando-se técnicas de transferência nuclear |
US20020142397A1 (en) | 2000-12-22 | 2002-10-03 | Philippe Collas | Methods for altering cell fate |
IL156746A0 (en) | 2001-01-02 | 2004-02-08 | Stemron Inc | A method for producing a population of homozygous stem cells having a pre-selected immunotype and/or genotype, cells suitable for transplant derived therefrom and materials and method using same |
JP2004529621A (ja) | 2001-02-14 | 2004-09-30 | ティー ファークト,レオ | 多能性成体幹細胞、その起源、それを得る方法および維持する方法、それを分化させる方法、その使用法、ならびにそれ由来の細胞 |
GB2392674B (en) * | 2001-07-06 | 2005-08-10 | Geron Corp | Mesenchymal cells and osteoblasts from human embryonic stem cell |
AU2002246132A1 (en) * | 2002-03-13 | 2003-09-22 | Fundacion Ivi Para El Estudio De La Reproduccion Humana (Fivier) | Method of producing cell lines |
US8034616B2 (en) | 2002-12-27 | 2011-10-11 | Mitsubishi Heavy Industries, Ltd. | Method and apparatus for cultivating multipotent stem cells |
JP5728676B2 (ja) * | 2004-11-04 | 2015-06-03 | オカタ セラピューティクス, インコーポレイテッド | 胚性幹細胞の誘導 |
US7893315B2 (en) | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
EP1878789A4 (en) * | 2005-04-14 | 2008-08-27 | Japan As Represented By Genera | STEM CELL DERIVED FROM FAT AND USE THEREOF |
CN102660495A (zh) | 2006-04-14 | 2012-09-12 | 先进细胞技术公司 | 血管瘤集落形成细胞 |
KR20150142061A (ko) | 2006-05-03 | 2015-12-21 | 오카타 세라퓨틱스, 인크. | 배아 줄기 세포 및 배-유도 세포의 유도 |
WO2008063675A2 (en) | 2006-11-24 | 2008-05-29 | Regents Of The University Of Minnesota | Endodermal progenitor cells |
AU2008218998A1 (en) * | 2007-02-23 | 2008-08-28 | Advanced Cell Technology, Inc. | Highly efficient methods for reprogramming differentiated cells and for generating animals and embryonic stem cells from reprogrammed cells |
CN102083960B (zh) | 2008-05-06 | 2014-12-03 | 先进细胞技术公司 | 用于制备衍生自多能干细胞的去核类红细胞的方法 |
EP2712921B1 (en) | 2008-05-06 | 2018-07-11 | Astellas Institute for Regenerative Medicine | Hemangio colony forming cells and non-engrafting hemangio cells |
US10386360B2 (en) | 2009-03-13 | 2019-08-20 | University Of Central Florida Research Foundation, Inc. | Bio-microelectromechanical system transducer and associated methods |
US8835168B2 (en) | 2009-04-23 | 2014-09-16 | University Of Central Florida Research Foundation, Inc. | Synthetic mammalian neuromuscular junction and method of making |
US8815584B1 (en) | 2009-04-23 | 2014-08-26 | University Of Central Florida Research Foundation, Inc. | Method of co-culturing mammalian muscle cells and motoneurons |
US9404140B1 (en) | 2009-11-03 | 2016-08-02 | The University Of Central Florida Research Foundation, Inc. | Patterned cardiomyocyte culture on microelectrode array |
JP2010193910A (ja) * | 2010-06-14 | 2010-09-09 | Mitsubishi Heavy Ind Ltd | 多能性幹細胞の培養方法、多能性幹細胞の培養システム、及び多能性幹細胞培養装置 |
WO2012022786A1 (de) | 2010-08-20 | 2012-02-23 | Hirschmann Automation And Control Gmbh | Erweiterung für das simple network management protocol (snmp) um informationen über den status von set-pdus zu ermitteln |
EP3636286A1 (en) * | 2011-05-18 | 2020-04-15 | The Regents of The University of California | Compositions and methods for treating retinal diseases |
WO2013010045A1 (en) | 2011-07-12 | 2013-01-17 | Biotime Inc. | Novel methods and formulations for orthopedic cell therapy |
JP6584956B2 (ja) | 2012-12-21 | 2019-10-02 | アステラス インスティテュート フォー リジェネレイティブ メディシン | 多能性幹細胞から血小板を生産するための方法およびその組成物 |
WO2014120952A1 (en) * | 2013-01-30 | 2014-08-07 | University Of Central Florida Research Foundation, Inc. | Devices and systems for mimicking heart function |
US10935541B2 (en) | 2014-08-07 | 2021-03-02 | University Of Central Florida Research Foundation, Inc. | Devices and methods comprising neuromuscular junctions |
US20180258400A1 (en) * | 2015-09-15 | 2018-09-13 | Agency For Science, Technology And Research (A*Star) | Derivation of liver organoids from human pluripotent stem cells |
BR112018073511A2 (pt) | 2016-05-16 | 2019-03-26 | Intarcia Therapeutics, Inc. | polipeptídeos seletivos do receptor de glucagon e métodos de uso dos mesmos |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH08502652A (ja) | 1992-10-28 | 1996-03-26 | ニューロスフィアーズ リミテッド | 生物学的因子と神経幹細胞 |
US5523226A (en) * | 1993-05-14 | 1996-06-04 | Biotechnology Research And Development Corp. | Transgenic swine compositions and methods |
US5532156A (en) * | 1993-10-08 | 1996-07-02 | The United States Of America As Represented By The Secretary Of Agriculture | Hepatocyte cell line derived from the epiblast of pig blastocysts |
US5843780A (en) * | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
EP0934403A4 (en) * | 1996-08-19 | 2001-03-14 | Univ Massachusetts | ROWS OF EMBRYONIC OR STRAIN-LIKE CELLS PRODUCED BY CROSS NUCLEAR TRANSPLANTATION OF SPECIES |
US5945577A (en) * | 1997-01-10 | 1999-08-31 | University Of Massachusetts As Represented By Its Amherst Campus | Cloning using donor nuclei from proliferating somatic cells |
CA2294916A1 (en) * | 1997-07-03 | 1999-01-14 | University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth As Represented By Its Amherst Campus | Cloning using donor nuclei from non-serum starved, differentiated cells |
KR100458403B1 (ko) * | 1997-09-29 | 2004-11-26 | 포인트 써러퓨틱스, 인크. | 생체외 조혈세포의 자극방법 |
CN1299408A (zh) * | 1998-03-02 | 2001-06-13 | 马萨诸塞大学 | 通过异种间的核移植产生的胚细胞或干细胞样细胞系 |
MXPA02002744A (es) * | 1999-09-14 | 2003-07-21 | Univ Massachusetts | Lineas de celulas embrionarias o tipo celulas madre y metodos para mejorar el desarrollo embrionario. |
US6576464B2 (en) * | 2000-11-27 | 2003-06-10 | Geron Corporation | Methods for providing differentiated stem cells |
AU2003302701A1 (en) * | 2002-11-29 | 2004-06-23 | Technion Research And Development Foundation Ltd. | Method of dynamically culturing embryonic stem cells |
-
2000
- 2000-10-13 BR BR0014864-4A patent/BR0014864A/pt not_active Application Discontinuation
- 2000-10-13 WO PCT/US2000/028285 patent/WO2001029206A1/en active IP Right Grant
- 2000-10-13 NZ NZ518191A patent/NZ518191A/en not_active IP Right Cessation
- 2000-10-13 JP JP2001532190A patent/JP2003512052A/ja active Pending
- 2000-10-13 AU AU12000/01A patent/AU782385B2/en not_active Ceased
- 2000-10-13 CN CN00817477A patent/CN1413250A/zh active Pending
- 2000-10-13 CA CA002388497A patent/CA2388497A1/en not_active Abandoned
- 2000-10-13 EP EP00973497A patent/EP1226239A4/en not_active Ceased
- 2000-10-13 MX MXPA02003733A patent/MXPA02003733A/es unknown
- 2000-10-13 IL IL14904300A patent/IL149043A0/xx unknown
-
2002
- 2002-04-09 IL IL149043A patent/IL149043A/en unknown
-
2004
- 2004-12-29 US US11/025,893 patent/US20050265976A1/en not_active Abandoned
-
2008
- 2008-05-16 US US12/152,779 patent/US8753884B2/en not_active Expired - Fee Related
-
2014
- 2014-05-07 US US14/272,365 patent/US20140248700A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN1413250A (zh) | 2003-04-23 |
US20140248700A1 (en) | 2014-09-04 |
IL149043A0 (en) | 2002-11-10 |
IL149043A (en) | 2010-11-30 |
CA2388497A1 (en) | 2001-04-26 |
US20050265976A1 (en) | 2005-12-01 |
NZ518191A (en) | 2004-01-30 |
US8753884B2 (en) | 2014-06-17 |
EP1226239A4 (en) | 2003-02-12 |
JP2003512052A (ja) | 2003-04-02 |
AU782385B2 (en) | 2005-07-21 |
EP1226239A1 (en) | 2002-07-31 |
WO2001029206A1 (en) | 2001-04-26 |
US20090104697A1 (en) | 2009-04-23 |
MXPA02003733A (es) | 2003-10-14 |
AU1200001A (en) | 2001-04-30 |
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