IL133786A0 - Cloning using donor nuclei from non-serum starved, differentiated cells - Google Patents

Cloning using donor nuclei from non-serum starved, differentiated cells

Info

Publication number
IL133786A0
IL133786A0 IL13378698A IL13378698A IL133786A0 IL 133786 A0 IL133786 A0 IL 133786A0 IL 13378698 A IL13378698 A IL 13378698A IL 13378698 A IL13378698 A IL 13378698A IL 133786 A0 IL133786 A0 IL 133786A0
Authority
IL
Israel
Prior art keywords
cloning
differentiated cells
serum starved
donor nuclei
nuclei
Prior art date
Application number
IL13378698A
Other languages
English (en)
Original Assignee
Univ Massachusetts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Massachusetts filed Critical Univ Massachusetts
Publication of IL133786A0 publication Critical patent/IL133786A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8771—Bovine embryos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/02—Cells from transgenic animals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/04—Cells produced using nuclear transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Psychology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
IL13378698A 1997-07-03 1998-06-24 Cloning using donor nuclei from non-serum starved, differentiated cells IL133786A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88828397A 1997-07-03 1997-07-03
PCT/US1998/012800 WO1999001163A1 (en) 1997-07-03 1998-06-24 Cloning using donor nuclei from non-serum starved, differentiated cells

Publications (1)

Publication Number Publication Date
IL133786A0 true IL133786A0 (en) 2001-04-30

Family

ID=25392916

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13378698A IL133786A0 (en) 1997-07-03 1998-06-24 Cloning using donor nuclei from non-serum starved, differentiated cells

Country Status (9)

Country Link
EP (1) EP1017422A4 (enExample)
JP (1) JP2001509361A (enExample)
CN (2) CN1265599A (enExample)
AU (1) AU8154398A (enExample)
BR (1) BR9811657A (enExample)
CA (1) CA2294916A1 (enExample)
IL (1) IL133786A0 (enExample)
NZ (1) NZ502129A (enExample)
WO (1) WO1999001163A1 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6235969B1 (en) * 1997-01-10 2001-05-22 University Of Massachusetts Cloning pigs using donor nuclei from non-quiescent differentiated cells
AU739902B2 (en) * 1998-01-16 2001-10-25 Agrobiogen Gmbh Efficient nuclear transfer using fetal fibroblasts
US6331659B1 (en) 1998-01-21 2001-12-18 University Of Hawaii Cumulus cells as nuclear donors
JP2002511234A (ja) * 1998-03-16 2002-04-16 リレグ ピーティーワイ リミテッド ブタの核移植
AUPP294898A0 (en) * 1998-04-15 1998-05-07 Monash University Method of nuclear transfer
US6781030B1 (en) 1998-11-02 2004-08-24 Trustee Of Tufts College, Ballou Hall Methods for cloning mammals using telophase oocytes
EP1818397A1 (en) * 1998-11-02 2007-08-15 Trustees Of Tufts College Methods for cloning animals
WO2000025578A2 (en) * 1999-04-26 2000-05-11 Trustees Of Tufts College Methods for cloning animals
EP1375654A3 (en) * 1998-11-02 2008-01-16 GTC Biotherapeutics, Inc. Transgenic and cloned mammals
DE60043578D1 (de) 1999-03-04 2010-02-04 Revivicor Inc Genetische veränderung von somatischen zellen und deren verwendungen
EP1117763A4 (en) * 1999-06-30 2004-12-01 Hwang Woo Suk PROCESS FOR PRODUCING CLONED TIGERS USING INTER-SPECIES CORE TRANSPLANTATION TECHNIQUE
WO2001000793A1 (en) * 1999-06-30 2001-01-04 Hwang, Woo-Suk Method for producing human cloned embryos by employing inter-species nuclear transplantation technique
WO2001000795A1 (en) * 1999-06-30 2001-01-04 Hwang, Woo-Suk A method for producing cloned cows
CA2388497A1 (en) * 1999-10-15 2001-04-26 Advanced Cell Technology, Inc. Method of producing differentiated progenitor cells by culturing morula or inner cell mass cells
GB2380202A (en) * 2000-06-08 2003-04-02 Trostner Jens Method for the genetic reconstruction of human organs
CA2422155A1 (en) 2000-08-03 2002-02-14 Wim Van Schooten Production of humanized antibodies in transgenic animals
FR2814642B1 (fr) 2000-10-03 2005-07-01 Ass Pour Le Dev De La Rech En Souris transgenique pour la recombinaison ciblee mediee par la cre-er modifiee
JP2004532648A (ja) * 2000-11-30 2004-10-28 ステムロン インコーポレイテッド 単離されたホモ接合性幹細胞、これ由来の分化細胞、ならびにこれを作製及び使用するための材料及び方法
KR100832943B1 (ko) * 2000-12-22 2008-05-27 기린 파마 가부시끼가이샤 재구성된 공여체 염색질 또는 공여체 세포를 이용한 포유류의 클로닝방법
ATE466089T1 (de) 2000-12-22 2010-05-15 Agronomique Inst Nat Rech Positionsunabhängige und gewebespezifische expression eines transgens in der milch eines transgen-tieres
EP1425386A4 (en) 2001-08-13 2007-05-02 Embrex Inc PROCESS FOR INJECTING BIRD EGGS
NZ535367A (en) * 2002-04-01 2008-01-31 Gtc Biotherapeutics Inc A method for selecting cell lines to be used for nuclear transfer in mammalian species
US7612250B2 (en) 2002-07-29 2009-11-03 Trustees Of Tufts College Nuclear transfer embryo formation method
RU2308281C1 (ru) * 2006-04-05 2007-10-20 ГУ Научно-исследовательский институт фармакологии Томского научного центра Сибирского отделения Российской академии медицинских наук (ГУ НИИ фармакологии ТНЦ СО РАМН) Способ клонирования in vitro регионарных стволовых клеток поджелудочной железы
WO2008027986A2 (en) 2006-09-01 2008-03-06 Therapeutic Human Polyclonals, Inc. Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals
EP2267153A1 (en) 2009-05-26 2010-12-29 Université Claude Bernard Lyon 1 Identification of netrin-1 receptor unc5c gene mutation in solid cancers
WO2013010045A1 (en) 2011-07-12 2013-01-17 Biotime Inc. Novel methods and formulations for orthopedic cell therapy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0739412B1 (en) * 1993-12-23 2002-02-27 Infigen, Inc. ungulate EMBRYONIC STEM CELLS AS NUCLEAR DONORS AND NUCLEAR TRANSFER TECHNIQUES TO PRODUCE CHIMERIC AND TRANSGENIC ANIMALS
GB9517779D0 (en) 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
GB9517780D0 (en) * 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
US5945577A (en) 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
AU739902B2 (en) * 1998-01-16 2001-10-25 Agrobiogen Gmbh Efficient nuclear transfer using fetal fibroblasts

Also Published As

Publication number Publication date
BR9811657A (pt) 2000-09-05
EP1017422A4 (en) 2002-10-29
WO1999001163A1 (en) 1999-01-14
EP1017422A1 (en) 2000-07-12
NZ502129A (en) 2005-02-25
AU8154398A (en) 1999-01-25
JP2001509361A (ja) 2001-07-24
CN1265599A (zh) 2000-09-06
CN101003800A (zh) 2007-07-25
CA2294916A1 (en) 1999-01-14

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