|
CA1223831A
(en)
|
1982-06-23 |
1987-07-07 |
Dean Engelhardt |
Modified nucleotides, methods of preparing and utilizing and compositions containing the same
|
|
US6008202A
(en)
*
|
1995-01-23 |
1999-12-28 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
|
US5795587A
(en)
*
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
|
US6056973A
(en)
*
|
1996-10-11 |
2000-05-02 |
Sequus Pharmaceuticals, Inc. |
Therapeutic liposome composition and method of preparation
|
|
US20070036722A1
(en)
*
|
1996-10-28 |
2007-02-15 |
Pal Rongved |
Separation processes
|
|
US6331289B1
(en)
|
1996-10-28 |
2001-12-18 |
Nycomed Imaging As |
Targeted diagnostic/therapeutic agents having more than one different vectors
|
|
US6210707B1
(en)
*
|
1996-11-12 |
2001-04-03 |
The Regents Of The University Of California |
Methods of forming protein-linked lipidic microparticles, and compositions thereof
|
|
JP2001510457A
(ja)
*
|
1996-11-12 |
2001-07-31 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
インビボ送達に有効な、脂質―核酸複合体の安定な製剤の調製
|
|
DE19745950A1
(de)
*
|
1997-10-17 |
1999-04-22 |
Dds Drug Delivery Service Ges |
Arzneistoffträgerpartikel für die gewebespezifische Arzneistoffapplikation
|
|
US6426086B1
(en)
*
|
1998-02-03 |
2002-07-30 |
The Regents Of The University Of California |
pH-sensitive, serum-stable liposomes
|
|
US6372720B1
(en)
|
1998-02-05 |
2002-04-16 |
Kenneth J. Longmuir |
Liposome fusion and delivery vehicle
|
|
US7087770B2
(en)
|
1998-05-16 |
2006-08-08 |
Mirus Bio Corporation |
Compound containing a labile disulfide bond
|
|
US6936729B2
(en)
*
|
1998-05-16 |
2005-08-30 |
Mirus Bio Corporation |
Compound containing a labile disulfide bond
|
|
BR9914601A
(pt)
|
1998-09-16 |
2001-10-23 |
Alza Corp |
Inibidor de topoisomerase capturado por lipossoma
|
|
CA2353593A1
(en)
*
|
1998-12-18 |
2000-06-22 |
Hadasit Medical Research Services & Development Ltd. |
Method of administering a compound to multi-drug resistant cells
|
|
US6379698B1
(en)
*
|
1999-04-06 |
2002-04-30 |
Isis Pharmaceuticals, Inc. |
Fusogenic lipids and vesicles
|
|
US6613352B2
(en)
|
1999-04-13 |
2003-09-02 |
Universite De Montreal |
Low-rigidity liposomal formulation
|
|
WO2000062813A2
(en)
*
|
1999-04-20 |
2000-10-26 |
The University Of British Columbia |
Cationic peg-lipids and methods of use
|
|
US6852334B1
(en)
|
1999-04-20 |
2005-02-08 |
The University Of British Columbia |
Cationic peg-lipids and methods of use
|
|
CA2368793A1
(en)
*
|
1999-04-23 |
2000-11-02 |
Alza Corporation |
Releasable linkage and compositions containing same
|
|
US7303760B2
(en)
*
|
1999-04-23 |
2007-12-04 |
Alza Corporation |
Method for treating multi-drug resistant tumors
|
|
KR100669053B1
(ko)
*
|
1999-04-23 |
2007-01-15 |
알자 코포레이션 |
리포좀에 사용하기 위한 절단가능 결합을 갖는 콘쥬게이트
|
|
US7238368B2
(en)
*
|
1999-04-23 |
2007-07-03 |
Alza Corporation |
Releasable linkage and compositions containing same
|
|
AUPQ014799A0
(en)
*
|
1999-05-04 |
1999-05-27 |
Access Pharmaceuticals Australia Pty Limited |
Amplification of folate-mediated targeting to tumor cells using polymers
|
|
AUPQ014699A0
(en)
*
|
1999-05-04 |
1999-05-27 |
Access Pharmaceuticals Australia Pty Limited |
Amplification of folate-mediated targeting to tumor cells using nanoparticles
|
|
EP1180242A1
(de)
*
|
1999-05-27 |
2002-02-20 |
Zeptosens AG |
Polymer-enthaltendes vesikel und darauf basierte sensor-nachweisverfahren
|
|
KR100758158B1
(ko)
|
1999-07-14 |
2007-09-12 |
알자 코포레이션 |
중성 지질중합체 및 그를 함유하는 리포솜 조성물
|
|
US20040197390A1
(en)
*
|
2001-05-29 |
2004-10-07 |
Shi-Kun Huang |
Neutral-cationic lipid for systemic delivery of factor VIII gene
|
|
WO2001026625A2
(en)
|
1999-10-08 |
2001-04-19 |
Alza Corp |
Neutral-cationic lipid for nucleic acid and drug delivery
|
|
US7067111B1
(en)
|
1999-10-25 |
2006-06-27 |
Board Of Regents, University Of Texas System |
Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
|
|
US6916488B1
(en)
*
|
1999-11-05 |
2005-07-12 |
Biocure, Inc. |
Amphiphilic polymeric vesicles
|
|
ES2320193T3
(es)
*
|
1999-11-24 |
2009-05-20 |
Transave, Inc. |
Sistema de suministro liposomico dirigido modular.
|
|
US20030147944A1
(en)
*
|
1999-12-10 |
2003-08-07 |
Mayer Lawrence D |
Lipid carrier compositions with protected surface reactive functions
|
|
PT1274399E
(pt)
*
|
2000-01-28 |
2005-07-29 |
Alza Corp |
Liposomas que contem um componente envolvente numa solucao supersaturada
|
|
US7189705B2
(en)
|
2000-04-20 |
2007-03-13 |
The University Of British Columbia |
Methods of enhancing SPLP-mediated transfection using endosomal membrane destabilizers
|
|
JP2004508012A
(ja)
*
|
2000-04-20 |
2004-03-18 |
ザ ユニバーシティ オブ ブリティッシュ コロンビア |
エンドソーム膜不安定剤を用いたsplp媒介性トランスフェクションの強化方法
|
|
US10293056B1
(en)
*
|
2000-05-24 |
2019-05-21 |
Board Of Regents, The University Of Texas System |
Methods and compositions for non-viral gene therapy for treatment of hyperproliferative diseases
|
|
ES2518926T3
(es)
|
2000-06-02 |
2014-11-05 |
Board Of Regents, The University Of Texas System |
Conjugados de etilendicisteína y un análogo de glucosa
|
|
US6998115B2
(en)
|
2000-10-10 |
2006-02-14 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
|
USRE43612E1
(en)
|
2000-10-10 |
2012-08-28 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
|
JP2004512345A
(ja)
*
|
2000-11-02 |
2004-04-22 |
スミスクライン・ビーチャム・コーポレイション |
受容体アンタゴニスト−脂質コンジュゲートおよびそれを含有するデリバリービヒクル
|
|
US6613280B2
(en)
|
2001-03-20 |
2003-09-02 |
Therox, Inc. |
Disposable cartridge for producing gas-enriched fluids
|
|
US20030003114A1
(en)
*
|
2001-03-22 |
2003-01-02 |
Pan Xing Qing |
Enzyme-based anti-cancer compositions and methods
|
|
US7108863B2
(en)
*
|
2001-03-26 |
2006-09-19 |
Alza Corporation |
Liposome composition for improved intracellular delivery of a therapeutic agent
|
|
JP2004535388A
(ja)
*
|
2001-04-30 |
2004-11-25 |
ターゲティッド ジェネティクス コーポレイション |
脂質含有薬物送達複合体およびそれらの生成方法
|
|
US20050176025A1
(en)
*
|
2001-05-18 |
2005-08-11 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of B-cell CLL/Lymphoma-2 (BCL-2) gene expression using short interfering nucleic acid (siNA)
|
|
US20050288242A1
(en)
*
|
2001-05-18 |
2005-12-29 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of RAS gene expression using short interfering nucleic acid (siNA)
|
|
US20050158735A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of proliferating cell nuclear antigen (PCNA) gene expression using short interfering nucleic acid (siNA)
|
|
US20050159382A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA)
|
|
EP1572067A4
(en)
*
|
2001-05-18 |
2009-05-13 |
Sirna Therapeutics Inc |
CONJUGATES AND COMPOSITIONS FOR CELLULAR RELEASE
|
|
US20050233997A1
(en)
*
|
2001-05-18 |
2005-10-20 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of matrix metalloproteinase 13 (MMP13) gene expression using short interfering nucleic acid (siNA)
|
|
US20050196765A1
(en)
*
|
2001-05-18 |
2005-09-08 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of checkpoint Kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA)
|
|
US20050203040A1
(en)
*
|
2001-05-18 |
2005-09-15 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA)
|
|
US20050196767A1
(en)
*
|
2001-05-18 |
2005-09-08 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of GRB2 associated binding protein (GAB2) gene expression using short interfering nucleic acis (siNA)
|
|
US20050124566A1
(en)
*
|
2001-05-18 |
2005-06-09 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of myostatin gene expression using short interfering nucleic acid (siNA)
|
|
AU2002329176A1
(en)
|
2001-05-25 |
2002-12-23 |
The Trustees Of The University Of Pennsylvania |
Targeted particles and methods of using the same
|
|
US6939564B2
(en)
*
|
2001-06-08 |
2005-09-06 |
Labopharm, Inc. |
Water-soluble stabilized self-assembled polyelectrolytes
|
|
EP1575976A4
(en)
|
2001-11-02 |
2006-08-23 |
Insert Therapeutics Inc |
METHODS AND COMPOSITIONS FOR THE THERAPEUTIC USE OF RNA INTERFERENCE
|
|
GB0129121D0
(en)
*
|
2001-12-05 |
2002-01-23 |
Ic Vec Ltd |
Compound
|
|
US9657294B2
(en)
|
2002-02-20 |
2017-05-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
|
US9181551B2
(en)
|
2002-02-20 |
2015-11-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
|
CA2503094A1
(en)
*
|
2002-02-27 |
2003-09-04 |
The Ohio State University Research Foundation |
Therapeutic methods for acute myeloid leukemia
|
|
US7018655B2
(en)
*
|
2002-03-18 |
2006-03-28 |
Labopharm, Inc. |
Amphiphilic diblock, triblock and star-block copolymers and their pharmaceutical compositions
|
|
WO2003083443A2
(en)
*
|
2002-03-29 |
2003-10-09 |
University Of Florida |
Lipid mediated screening of drug candidates for identification of active compounds
|
|
AU2003278691A1
(en)
*
|
2002-04-23 |
2004-02-02 |
The Research Foundation Of State University Of New York |
Polymer surfactants for gene therapy applications
|
|
US20040022842A1
(en)
*
|
2002-06-03 |
2004-02-05 |
Mebiopharm Co., Ltd. |
Liposome preparations containing oxaliplatin
|
|
JP3415131B1
(ja)
*
|
2002-06-03 |
2003-06-09 |
メビオファーム株式会社 |
リポソーム製剤
|
|
US20040093198A1
(en)
*
|
2002-11-08 |
2004-05-13 |
Carbon Design Systems |
Hardware simulation with access restrictions
|
|
EP1581582B2
(en)
|
2003-01-06 |
2017-06-07 |
Nektar Therapeutics |
Thiol-selective water-soluble polmer derivatives
|
|
EP1591450A4
(en)
*
|
2003-01-10 |
2006-05-17 |
Yamanouchi Pharma Co Ltd |
CONJUGATE FOR RETENTION IN THE BLOOD AND CANCER-SPECIFIC ACTIVE EXTRACTION
|
|
EP1596829A2
(en)
*
|
2003-02-28 |
2005-11-23 |
Alza Corporation |
Liposome composition for reduction of liposome-induced complement activation
|
|
CA2520864A1
(en)
|
2003-03-31 |
2004-10-21 |
Alza Corporation |
Lipid particles having asymmetric lipid coating and method of preparing same
|
|
KR20060015265A
(ko)
*
|
2003-05-30 |
2006-02-16 |
알자 코포레이션 |
제제의 폐 투여 방법
|
|
US11324698B2
(en)
|
2003-08-28 |
2022-05-10 |
Vgsk Technologies, Inc. |
Sterically stabilized carrier for aerosol therapeutics, compositions and methods for treating the respiratory tract of a mammal
|
|
US8846079B1
(en)
*
|
2004-12-01 |
2014-09-30 |
Vgsk Technologies, Inc. |
Sterically stabilized carrier for aerosol therapeutics, compositions and methods for treating the respiratory tract of a mammal
|
|
CA2560901C
(en)
*
|
2003-08-29 |
2012-08-21 |
The University Of Newcastle Research Associates Limited |
Stimulant sensitive flocculation and consolidation
|
|
US7943179B2
(en)
|
2003-09-23 |
2011-05-17 |
Massachusetts Institute Of Technology |
pH triggerable polymeric particles
|
|
JP2007533647A
(ja)
*
|
2003-10-24 |
2007-11-22 |
アルザ・コーポレーシヨン |
脂質粒子の調製
|
|
US9050378B2
(en)
*
|
2003-12-10 |
2015-06-09 |
Board Of Regents, The University Of Texas System |
N2S2 chelate-targeting ligand conjugates
|
|
EP1706149A2
(en)
*
|
2004-01-15 |
2006-10-04 |
Alza Corporation |
Liposome composition for delivery of therapeutic agents
|
|
US8017151B2
(en)
*
|
2004-09-07 |
2011-09-13 |
Board Of Regents Of The University Of Nebraska By And Behalf Of The University Of Nebraska Medical Center |
Amphiphilic polymer-protein conjugates and methods of use thereof
|
|
US8168222B2
(en)
|
2004-09-07 |
2012-05-01 |
Board Of Regents Of The University Of Nebraska |
Amphiphilic polymer-protein conjugates and methods of use thereof
|
|
ATE401057T1
(de)
*
|
2004-10-08 |
2008-08-15 |
Alza Corp |
Verfahren zur einführung eines lipid-verknüpften teils in eine vorgeformte lipidanordnung mit mikrowellen
|
|
CN101238142B
(zh)
*
|
2005-02-18 |
2012-11-14 |
国立大学法人德岛大学 |
含聚氧化烯链的脂质衍生物及含有该衍生物的脂质膜结构体
|
|
JP2006248978A
(ja)
*
|
2005-03-10 |
2006-09-21 |
Mebiopharm Co Ltd |
新規なリポソーム製剤
|
|
KR20080042045A
(ko)
*
|
2005-05-23 |
2008-05-14 |
에스디지,인코포레이티드 |
포유동물로의 인터페론 전달용 지질 구조물
|
|
EP1891141B1
(en)
|
2005-05-31 |
2016-11-16 |
Ecole Polytechnique Fédérale de Lausanne (EPFL) |
Triblock copolymers for cytoplasmic delivery of gene-based drugs
|
|
HUE029994T2
(en)
|
2005-12-08 |
2017-04-28 |
Insmed Inc |
Lipid-based compositions of antiinfectives for treating pulmonary infections
|
|
WO2007092944A2
(en)
*
|
2006-02-08 |
2007-08-16 |
Introgen Therapeutics, Inc. |
Compositions and methods involving gene therapy and proteasome modulation
|
|
US8758723B2
(en)
|
2006-04-19 |
2014-06-24 |
The Board Of Regents Of The University Of Texas System |
Compositions and methods for cellular imaging and therapy
|
|
WO2007143659A2
(en)
|
2006-06-05 |
2007-12-13 |
Massachusetts Institute Of Technology |
Crosslinked, degradable polymers and uses thereof
|
|
US20080031883A1
(en)
*
|
2006-07-13 |
2008-02-07 |
Torchilin Vladimir P |
Condition-dependent, multiple target delivery system
|
|
US8343539B2
(en)
*
|
2006-07-14 |
2013-01-01 |
Regents Of The University Of Minnesota |
Compounds that bind α5β1 integrin and methods of use
|
|
CA2658768C
(en)
|
2006-07-21 |
2016-05-17 |
Massachusetts Institute Of Technology |
End-modified poly(beta-amino esters) and uses thereof
|
|
US20080213349A1
(en)
*
|
2006-09-11 |
2008-09-04 |
Deepak Ramesh Thakker |
Liposome Complexes Containing Pharmaceutical Agents and Methods
|
|
MX2009003092A
(es)
*
|
2006-09-22 |
2009-05-08 |
Labopharm Inc |
Composiciones y metodos para suministro de farmaco dirigido a ph.
|
|
US10925977B2
(en)
*
|
2006-10-05 |
2021-02-23 |
Ceil>Point, LLC |
Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
|
|
US9119783B2
(en)
|
2007-05-07 |
2015-09-01 |
Insmed Incorporated |
Method of treating pulmonary disorders with liposomal amikacin formulations
|
|
WO2009006311A2
(en)
*
|
2007-06-29 |
2009-01-08 |
Wisconsin Alumni Research Foundation |
Structuring effect of cholesterol in peg-phospholipid micelles, drug delivery of amphotericin b, and combination antifungals
|
|
US20110105995A1
(en)
*
|
2008-01-16 |
2011-05-05 |
Zhu Ting F |
Uniform-sized, multi-drug carrying, and photosensitive liposomes for advanced drug delivery
|
|
WO2009154688A1
(en)
*
|
2008-05-28 |
2009-12-23 |
President And Fellows Of Harvard College |
A pre-fabricated electron microscopy grid for monolayer purification and methods and kits therefor
|
|
US8173621B2
(en)
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
|
JP5642673B2
(ja)
|
2008-07-10 |
2014-12-17 |
セリナ・セラピユーテイツクス・インコーポレーテツド |
不活性末端基を有するポリオキサゾリン類、保護された開始基から調製されるポリオキサゾリン類及び関連化合物
|
|
ES2646630T3
(es)
|
2008-11-07 |
2017-12-14 |
Massachusetts Institute Of Technology |
Lipidoides aminoalcohólicos y usos de los mismos
|
|
JP5814793B2
(ja)
|
2008-11-25 |
2015-11-17 |
エコール ポリテクニク フェデラル ド ローザンヌ(エーペーエフエル) |
ブロックコポリマーおよびその使用
|
|
KR20110098849A
(ko)
|
2008-12-23 |
2011-09-01 |
파마셋 인코포레이티드 |
뉴클레오시드 유사체
|
|
PT2376088T
(pt)
|
2008-12-23 |
2017-05-02 |
Gilead Pharmasset Llc |
Fosforamidatos de nucleósidos de 2-amino-purina 6-osubstituída
|
|
SG194404A1
(en)
|
2008-12-23 |
2013-11-29 |
Gilead Pharmasset Llc |
Synthesis of purine nucleosides
|
|
EP2230515B1
(en)
*
|
2009-03-16 |
2014-12-17 |
Agilent Technologies, Inc. |
Passivation of surfaces after ligand coupling
|
|
KR20180094137A
(ko)
*
|
2009-05-05 |
2018-08-22 |
알닐람 파마슈티칼스 인코포레이티드 |
지질 조성물
|
|
TWI598358B
(zh)
|
2009-05-20 |
2017-09-11 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
|
US9937128B2
(en)
*
|
2009-08-03 |
2018-04-10 |
The University Of North Carolina At Chapel Hill |
Liposomes comprising a calcium phosphate-containing precipitate
|
|
JP4912510B2
(ja)
|
2009-08-31 |
2012-04-11 |
ナノキャリア株式会社 |
粒子組成物及びこれを有する医薬組成物
|
|
HUE042177T2
(hu)
|
2009-12-01 |
2019-06-28 |
Translate Bio Inc |
Szteroidszármazék mRNS szállítására humán genetikai betegségekben
|
|
JP4829351B2
(ja)
|
2010-02-05 |
2011-12-07 |
ナノキャリア株式会社 |
易崩壊型ポリマーミセル組成物
|
|
PT2609923T
(pt)
|
2010-03-31 |
2017-08-30 |
Gilead Pharmasset Llc |
Processo para a cristalização de 2-(((s)- (perfluorofenoxi)(fenoxi)fosforil)amino)propanoato de (s)-isopropilo
|
|
PL3290428T3
(pl)
|
2010-03-31 |
2022-02-07 |
Gilead Pharmasset Llc |
Tabletka zawierająca krystaliczny (S)-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-diokso-3,4-dihydropirymidyn-1(2H)-ylo)-4-fluoro-3-hydroksy-4-metylotetrahydrofuran-2-ylo)metoksy)(fenoksy)fosforylo)amino)propanian izopropylu
|
|
UY33312A
(es)
|
2010-03-31 |
2011-10-31 |
Pharmasset Inc |
Fosforamidato de nucleosido de purina
|
|
CN105153307A
(zh)
|
2010-05-04 |
2015-12-16 |
梅里麦克制药股份有限公司 |
抗表皮生长因子受体(egfr)的抗体及其用途
|
|
JP2013529638A
(ja)
*
|
2010-06-19 |
2013-07-22 |
ウェスタン ユニバーシティ オブ ヘルス サイエンス |
Peg化リポソーム封入糖ペプチド抗生物質の新規製剤
|
|
EP2609135A4
(en)
|
2010-08-26 |
2015-05-20 |
Massachusetts Inst Technology |
POLY (BETA AMINO ALCOHOLS), THEIR PREPARATION AND USES THEREOF
|
|
WO2012058210A1
(en)
|
2010-10-29 |
2012-05-03 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (siNA)
|
|
AU2011336632B2
(en)
|
2010-11-30 |
2015-09-03 |
Gilead Pharmasset Llc |
Compounds
|
|
US9238716B2
(en)
|
2011-03-28 |
2016-01-19 |
Massachusetts Institute Of Technology |
Conjugated lipomers and uses thereof
|
|
ES2762224T3
(es)
*
|
2011-05-12 |
2020-05-22 |
Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd |
Liposomas que comprenden lípidos conjugados con polímero y usos relacionados
|
|
US8691231B2
(en)
|
2011-06-03 |
2014-04-08 |
Merrimack Pharmaceuticals, Inc. |
Methods of treatment of tumors expressing predominantly high affinity EGFR ligands or tumors expressing predominantly low affinity EGFR ligands with monoclonal and oligoclonal anti-EGFR antibodies
|
|
PL3586861T3
(pl)
|
2011-06-08 |
2022-05-23 |
Translate Bio, Inc. |
Kompozycje nanocząstek lipidowych i sposoby dostarczania mrna
|
|
US8883989B2
(en)
|
2011-10-18 |
2014-11-11 |
Regents Of The University Of Minnesota |
Fractalkine binding polynucleotides and methods of use
|
|
KR102451116B1
(ko)
|
2011-10-27 |
2022-10-06 |
메사추세츠 인스티튜트 오브 테크놀로지 |
약물 캡슐화 마이크로스피어를 형성할 수 있는, n-말단 상에 관능화된 아미노산 유도체
|
|
EP3536787A1
(en)
|
2012-06-08 |
2019-09-11 |
Translate Bio, Inc. |
Nuclease resistant polynucleotides and uses thereof
|
|
WO2014015027A1
(en)
|
2012-07-18 |
2014-01-23 |
Onyx Therapeutics, Inc. |
Liposomal compositions of epoxyketone-based proteasome inhibitors
|
|
CN102920658B
(zh)
*
|
2012-11-02 |
2015-01-21 |
艾韦特(溧阳)医药科技有限公司 |
与glp-1类似物和聚乙二醇结合的脂质体及其制备方法
|
|
RU2018135921A
(ru)
|
2012-11-29 |
2019-02-05 |
Инсмед Инкорпорейтед |
Стабилизированные составы ванкомицина
|
|
CN105188675A
(zh)
*
|
2013-03-13 |
2015-12-23 |
马林克罗特有限公司 |
经修饰多西他赛脂质体制剂
|
|
PL3467108T3
(pl)
|
2013-03-14 |
2024-09-30 |
Translate Bio, Inc. |
Sposoby oczyszczania informacyjnego rna
|
|
KR20210122917A
(ko)
|
2013-03-14 |
2021-10-12 |
샤이어 휴먼 지네틱 테라피즈 인크. |
Cftr mrna 조성물 및 관련 방법 및 사용
|
|
US10711106B2
(en)
|
2013-07-25 |
2020-07-14 |
The University Of Chicago |
High aspect ratio nanofibril materials
|
|
ES2707966T3
(es)
|
2013-10-22 |
2019-04-08 |
Translate Bio Inc |
Terapia de ARNm para la deficiencia en síntesis de argininosuccinato
|
|
EA034103B1
(ru)
|
2013-10-22 |
2019-12-27 |
Транслейт Био, Инк. |
СПОСОБ ЛЕЧЕНИЯ ФЕНИЛКЕТОНУРИИ С ПРИМЕНЕНИЕМ мРНК
|
|
MX2016005238A
(es)
|
2013-10-22 |
2016-08-12 |
Shire Human Genetic Therapies |
Formulaciones de lipidos para la administracion de acido ribonucleico mensajero.
|
|
AU2014348683B2
(en)
|
2013-11-18 |
2020-11-05 |
Rubius Therapeutics, Inc. |
Synthetic membrane-receiver complexes
|
|
ES2939542T3
(es)
|
2014-01-31 |
2023-04-24 |
Factor Bioscience Inc |
Métodos y productos para la producción y la administración de ácido nucleico
|
|
WO2015148971A2
(en)
|
2014-03-27 |
2015-10-01 |
Research Foundation Of The City University Of New York |
Method for detecting or treating triple negative breast cancer
|
|
ES2865825T3
(es)
|
2014-04-01 |
2021-10-18 |
Rubius Therapeutics Inc |
Procedimientos y composiciones para inmunomodulación
|
|
PT3134506T
(pt)
|
2014-04-25 |
2019-10-31 |
Translate Bio Inc |
Métodos de purificação de rna mensageiro
|
|
SMT202000516T1
(it)
|
2014-05-15 |
2020-11-10 |
Insmed Inc |
Metodi per trattamento di infezioni micobatteriche polmonati non tubercolari
|
|
JP6557722B2
(ja)
|
2014-05-30 |
2019-08-07 |
シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド |
核酸の送達のための生分解性脂質
|
|
EP3160959B1
(en)
|
2014-06-24 |
2023-08-30 |
Translate Bio, Inc. |
Stereochemically enriched compositions for delivery of nucleic acids
|
|
US9840479B2
(en)
|
2014-07-02 |
2017-12-12 |
Massachusetts Institute Of Technology |
Polyamine-fatty acid derived lipidoids and uses thereof
|
|
CN104546722B
(zh)
*
|
2015-02-10 |
2017-05-24 |
中国医学科学院医药生物技术研究所 |
米铂脂质体和制法
|
|
JP7199809B2
(ja)
|
2015-02-13 |
2023-01-06 |
ファクター バイオサイエンス インコーポレイテッド |
核酸製品及びその投与方法
|
|
ES2949540T3
(es)
|
2015-06-19 |
2023-09-29 |
Massachusetts Inst Technology |
2,5-piperazinadionas sustituidas con alquenilo y su uso en composiciones para suministrar un agente a un sujeto o una célula
|
|
CN114533898B
(zh)
*
|
2015-07-09 |
2025-07-01 |
加利福尼亚大学董事会 |
融合脂质体包被的多孔硅纳米颗粒
|
|
EP3349729A4
(en)
|
2015-09-14 |
2019-06-26 |
VGSK Technologies, Inc. |
STERILE-STABILIZED CARRIER FOR SUBCUTANEOUS, SUB-LINGUAL AND ORAL THERAPEUTICS, COMPOSITIONS AND METHOD FOR TREATING ANIMALS
|
|
US10583083B1
(en)
|
2016-08-10 |
2020-03-10 |
Verily Life Sciences Llc |
ROS-responsive multilamellar liposomal vesicles for targeting inflammatory macrophages
|
|
US10517823B1
(en)
*
|
2016-08-10 |
2019-12-31 |
Verily Life Sciences Llc |
ROS—responsive liposomes for specific targeting
|
|
US10576167B2
(en)
|
2016-08-17 |
2020-03-03 |
Factor Bioscience Inc. |
Nucleic acid products and methods of administration thereof
|
|
EP3538546B1
(en)
|
2016-11-14 |
2025-01-08 |
Novartis AG |
Compositions, methods, and therapeutic uses related to fusogenic protein minion
|
|
EA201991747A1
(ru)
|
2017-02-27 |
2020-06-04 |
Транслейт Био, Инк. |
НОВАЯ КОДОН-ОПТИМИЗИРОВАННАЯ мРНК CFTR
|
|
US11260132B2
(en)
|
2017-03-16 |
2022-03-01 |
Children's Medical Center Corporation |
Engineered liposomes as cancer-targeted therapeutics
|
|
JP2020517750A
(ja)
*
|
2017-04-19 |
2020-06-18 |
エイピーエイ− アドバンスト・テクノロジーズ・リミテッドApa− Advanced Technologies Ltd. |
癌処置のための融合性リポソーム、組成物、キットおよびその使用
|
|
MX2019013752A
(es)
|
2017-05-16 |
2020-07-20 |
Translate Bio Inc |
Tratamiento de la fibrosis quística mediante el suministro de arnm que codifica cftr optimizado en codones.
|
|
US11464860B2
(en)
|
2017-10-27 |
2022-10-11 |
Massachusetts Institute Of Technology |
Poly (beta-amino esters) and uses thereof
|
|
EP3773505B1
(en)
|
2018-03-30 |
2026-04-29 |
Insmed Incorporated |
Methods for continuous manufacture of liposomal drug products
|
|
WO2019213398A1
(en)
|
2018-05-02 |
2019-11-07 |
Insmed Incorporated |
Methods for the manufacture of liposomal drug formulations
|
|
CA3108544A1
(en)
|
2018-08-24 |
2020-02-27 |
Translate Bio, Inc. |
Methods for purification of messenger rna
|
|
WO2020084623A2
(en)
*
|
2018-10-24 |
2020-04-30 |
Apa- Advanced Technologies Ltd. |
Fusogenic liposomes for selective imaging of tumor cells
|
|
CA3117781A1
(en)
|
2018-10-26 |
2020-04-30 |
Massachusetts Institute Of Technology |
Polymer-lipids and compositions
|
|
MX2021005969A
(es)
|
2018-11-21 |
2021-09-14 |
Translate Bio Inc |
Tratamiento de la fibrosis quística mediante el suministro de arnm que codifica cftr nebulizado.
|
|
US12433847B2
(en)
|
2021-03-09 |
2025-10-07 |
Massachusetts Institute Of Technology |
Branched poly(-amino esters) for the delivery of nucleic acids
|
|
WO2022235907A1
(en)
|
2021-05-05 |
2022-11-10 |
Vgsk Technologies, Inc. |
Liposome-encapsulated corticosteriods inhibit sars-cov-2 replication and reduces lung inflammation
|
|
JPWO2023210671A1
(https=)
*
|
2022-04-26 |
2023-11-02 |
|
|