|
CA1223831A
(en)
|
1982-06-23 |
1987-07-07 |
Dean Engelhardt |
Modified nucleotides, methods of preparing and utilizing and compositions containing the same
|
|
US6008202A
(en)
*
|
1995-01-23 |
1999-12-28 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
|
US5795587A
(en)
*
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
|
US6056973A
(en)
*
|
1996-10-11 |
2000-05-02 |
Sequus Pharmaceuticals, Inc. |
Therapeutic liposome composition and method of preparation
|
|
US20070036722A1
(en)
*
|
1996-10-28 |
2007-02-15 |
Pal Rongved |
Separation processes
|
|
US6331289B1
(en)
|
1996-10-28 |
2001-12-18 |
Nycomed Imaging As |
Targeted diagnostic/therapeutic agents having more than one different vectors
|
|
US6210707B1
(en)
|
1996-11-12 |
2001-04-03 |
The Regents Of The University Of California |
Methods of forming protein-linked lipidic microparticles, and compositions thereof
|
|
JP2001510457A
(ja)
*
|
1996-11-12 |
2001-07-31 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
インビボ送達に有効な、脂質―核酸複合体の安定な製剤の調製
|
|
DE19745950A1
(de)
*
|
1997-10-17 |
1999-04-22 |
Dds Drug Delivery Service Ges |
Arzneistoffträgerpartikel für die gewebespezifische Arzneistoffapplikation
|
|
US6426086B1
(en)
*
|
1998-02-03 |
2002-07-30 |
The Regents Of The University Of California |
pH-sensitive, serum-stable liposomes
|
|
US6372720B1
(en)
|
1998-02-05 |
2002-04-16 |
Kenneth J. Longmuir |
Liposome fusion and delivery vehicle
|
|
US7087770B2
(en)
|
1998-05-16 |
2006-08-08 |
Mirus Bio Corporation |
Compound containing a labile disulfide bond
|
|
US6936729B2
(en)
*
|
1998-05-16 |
2005-08-30 |
Mirus Bio Corporation |
Compound containing a labile disulfide bond
|
|
DE69907243T2
(de)
|
1998-09-16 |
2004-02-19 |
Alza Corp., Mountain View |
In liposomen eingeschlossene topoisomerase inhibitoren
|
|
MXPA01006201A
(es)
*
|
1998-12-18 |
2003-06-06 |
Hadasit Med Res Service |
Metodo para administrar un compuesto a celulas resistentes a multiples medicamentos.
|
|
US6379698B1
(en)
*
|
1999-04-06 |
2002-04-30 |
Isis Pharmaceuticals, Inc. |
Fusogenic lipids and vesicles
|
|
US6613352B2
(en)
|
1999-04-13 |
2003-09-02 |
Universite De Montreal |
Low-rigidity liposomal formulation
|
|
JP5117648B2
(ja)
*
|
1999-04-20 |
2013-01-16 |
ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア |
カチオン性ｐｅｇ脂質および使用方法。
|
|
US6852334B1
(en)
*
|
1999-04-20 |
2005-02-08 |
The University Of British Columbia |
Cationic peg-lipids and methods of use
|
|
CN100512879C
(zh)
*
|
1999-04-23 |
2009-07-15 |
阿尔萨公司 |
用于脂质体中的有可裂解键的缀合物
|
|
US7303760B2
(en)
*
|
1999-04-23 |
2007-12-04 |
Alza Corporation |
Method for treating multi-drug resistant tumors
|
|
US7238368B2
(en)
*
|
1999-04-23 |
2007-07-03 |
Alza Corporation |
Releasable linkage and compositions containing same
|
|
IL146047A0
(en)
*
|
1999-04-23 |
2002-07-25 |
Alza Corp |
Releasable linkage and compositions containing same
|
|
AUPQ014699A0
(en)
*
|
1999-05-04 |
1999-05-27 |
Access Pharmaceuticals Australia Pty Limited |
Amplification of folate-mediated targeting to tumor cells using nanoparticles
|
|
AUPQ014799A0
(en)
*
|
1999-05-04 |
1999-05-27 |
Access Pharmaceuticals Australia Pty Limited |
Amplification of folate-mediated targeting to tumor cells using polymers
|
|
AU5395000A
(en)
*
|
1999-05-27 |
2000-12-18 |
Zeptosens Ag |
Vesicle containing polymers and sensor detection methods based thereon
|
|
ATE317869T1
(de)
*
|
1999-07-14 |
2006-03-15 |
Alza Corp |
Neutrales lipopolymer und liposomale zusammensetzungen daraus
|
|
US20040197390A1
(en)
*
|
2001-05-29 |
2004-10-07 |
Shi-Kun Huang |
Neutral-cationic lipid for systemic delivery of factor VIII gene
|
|
WO2001026625A2
(en)
*
|
1999-10-08 |
2001-04-19 |
Alza Corp |
Neutral-cationic lipid for nucleic acid and drug delivery
|
|
US7067111B1
(en)
*
|
1999-10-25 |
2006-06-27 |
Board Of Regents, University Of Texas System |
Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
|
|
US6916488B1
(en)
*
|
1999-11-05 |
2005-07-12 |
Biocure, Inc. |
Amphiphilic polymeric vesicles
|
|
AU1776801A
(en)
*
|
1999-11-24 |
2001-06-04 |
Liposome Company, Inc., The |
Modular targeted liposomal delivery system
|
|
CA2393595A1
(en)
*
|
1999-12-10 |
2001-06-14 |
Gigi Chiu |
Lipid carrier compositions with protected surface reactive functions
|
|
WO2001054666A1
(en)
*
|
2000-01-28 |
2001-08-02 |
Alza Corporation |
Liposomes containing an entrapped compound in supersaturated solution
|
|
WO2001080900A2
(en)
*
|
2000-04-20 |
2001-11-01 |
The University Of British Columbia |
Enhanced stabilised plasmid-lipid particle-mediated transfection using endosomal membrane
|
|
US7189705B2
(en)
|
2000-04-20 |
2007-03-13 |
The University Of British Columbia |
Methods of enhancing SPLP-mediated transfection using endosomal membrane destabilizers
|
|
US10293056B1
(en)
*
|
2000-05-24 |
2019-05-21 |
Board Of Regents, The University Of Texas System |
Methods and compositions for non-viral gene therapy for treatment of hyperproliferative diseases
|
|
JP5448284B2
(ja)
|
2000-06-02 |
2014-03-19 |
ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム |
エチレンジシステイン（ｅｃ）−薬物結合体
|
|
USRE43612E1
(en)
|
2000-10-10 |
2012-08-28 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
|
US6998115B2
(en)
|
2000-10-10 |
2006-02-14 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
|
WO2002036073A2
(en)
*
|
2000-11-02 |
2002-05-10 |
Smithkline Beecham Corporation |
Receptor antagonist-lipid conjugates and delivery vehicles containing same
|
|
US6613280B2
(en)
|
2001-03-20 |
2003-09-02 |
Therox, Inc. |
Disposable cartridge for producing gas-enriched fluids
|
|
WO2002076394A2
(en)
*
|
2001-03-22 |
2002-10-03 |
The Ohio State University Research Foundation |
Enzyme-based anti-cancer compositions and methods
|
|
MXPA03008864A
(es)
*
|
2001-03-26 |
2004-12-06 |
Johnson & Johnson |
Composicion de liposoma para el suministro intracelular mejorado en un agente terapeutico.
|
|
WO2002088318A2
(en)
*
|
2001-04-30 |
2002-11-07 |
Targeted Genetics Corporation |
Lipid-comprising drug delivery complexes and methods for their production
|
|
US20050159382A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA)
|
|
US20050196765A1
(en)
*
|
2001-05-18 |
2005-09-08 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of checkpoint Kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA)
|
|
US20050233997A1
(en)
*
|
2001-05-18 |
2005-10-20 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of matrix metalloproteinase 13 (MMP13) gene expression using short interfering nucleic acid (siNA)
|
|
US20050288242A1
(en)
*
|
2001-05-18 |
2005-12-29 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of RAS gene expression using short interfering nucleic acid (siNA)
|
|
US20050196767A1
(en)
*
|
2001-05-18 |
2005-09-08 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of GRB2 associated binding protein (GAB2) gene expression using short interfering nucleic acis (siNA)
|
|
US20050124566A1
(en)
*
|
2001-05-18 |
2005-06-09 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of myostatin gene expression using short interfering nucleic acid (siNA)
|
|
US20050203040A1
(en)
*
|
2001-05-18 |
2005-09-15 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA)
|
|
AU2002316135B9
(en)
*
|
2001-05-18 |
2009-05-28 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery
|
|
US20050176025A1
(en)
*
|
2001-05-18 |
2005-08-11 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of B-cell CLL/Lymphoma-2 (BCL-2) gene expression using short interfering nucleic acid (siNA)
|
|
US20050158735A1
(en)
*
|
2001-05-18 |
2005-07-21 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of proliferating cell nuclear antigen (PCNA) gene expression using short interfering nucleic acid (siNA)
|
|
WO2002100317A2
(en)
|
2001-05-25 |
2002-12-19 |
The Trustees Of The University Of Pennsylvania |
Targeted particles and methods of using the same
|
|
US6939564B2
(en)
*
|
2001-06-08 |
2005-09-06 |
Labopharm, Inc. |
Water-soluble stabilized self-assembled polyelectrolytes
|
|
AU2002368202B2
(en)
|
2001-11-02 |
2008-06-05 |
Insert Therapeutics, Inc |
Methods and compositions for therapeutic use of RNA interference
|
|
GB0129121D0
(en)
*
|
2001-12-05 |
2002-01-23 |
Ic Vec Ltd |
Compound
|
|
US9181551B2
(en)
|
2002-02-20 |
2015-11-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
|
US9657294B2
(en)
|
2002-02-20 |
2017-05-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
|
WO2003072091A1
(en)
*
|
2002-02-27 |
2003-09-04 |
The Ohio State University Research Foundation |
Therapeutic methods for acute myeloid leukemia
|
|
US7018655B2
(en)
*
|
2002-03-18 |
2006-03-28 |
Labopharm, Inc. |
Amphiphilic diblock, triblock and star-block copolymers and their pharmaceutical compositions
|
|
US20030198664A1
(en)
*
|
2002-03-29 |
2003-10-23 |
Sullivan Sean Michael |
Lipid mediated screening of drug candidates for identification of active compounds
|
|
US20060094673A1
(en)
*
|
2002-04-23 |
2006-05-04 |
Benjamin Chu |
Polymer surfactants for gene therapy applications
|
|
US20040022842A1
(en)
*
|
2002-06-03 |
2004-02-05 |
Mebiopharm Co., Ltd. |
Liposome preparations containing oxaliplatin
|
|
JP3415131B1
(ja)
*
|
2002-06-03 |
2003-06-09 |
メビオファーム株式会社 |
リポソーム製剤
|
|
US20040093198A1
(en)
*
|
2002-11-08 |
2004-05-13 |
Carbon Design Systems |
Hardware simulation with access restrictions
|
|
CA2509939C
(en)
|
2003-01-06 |
2013-05-21 |
Nektar Therapeutics Al, Corporation |
Thiol-selective water-soluble polymer derivatives
|
|
WO2004063216A1
(ja)
*
|
2003-01-10 |
2004-07-29 |
Yamanouchi Pharmaceutical Co., Ltd. |
血中滞留および癌組織特異的薬物送達のためのコンジュゲート
|
|
RU2005130172A
(ru)
*
|
2003-02-28 |
2006-03-20 |
Алза Корпорейшн (Us) Бus |
Липосомные композиции для уменьшения активизации комплемента, вызванной липосомами
|
|
WO2004089339A2
(en)
*
|
2003-03-31 |
2004-10-21 |
Alza Corporation |
Lipid particles having asymmetric lipid coating and method of preparing same
|
|
JP2007500239A
(ja)
*
|
2003-05-30 |
2007-01-11 |
アルザ・コーポレーシヨン |
薬剤の肺投与の方法
|
|
US11324698B2
(en)
|
2003-08-28 |
2022-05-10 |
Vgsk Technologies, Inc. |
Sterically stabilized carrier for aerosol therapeutics, compositions and methods for treating the respiratory tract of a mammal
|
|
US8846079B1
(en)
*
|
2004-12-01 |
2014-09-30 |
Vgsk Technologies, Inc. |
Sterically stabilized carrier for aerosol therapeutics, compositions and methods for treating the respiratory tract of a mammal
|
|
CA2560901C
(en)
*
|
2003-08-29 |
2012-08-21 |
The University Of Newcastle Research Associates Limited |
Stimulant sensitive flocculation and consolidation
|
|
US7943179B2
(en)
|
2003-09-23 |
2011-05-17 |
Massachusetts Institute Of Technology |
pH triggerable polymeric particles
|
|
EP1677765A1
(en)
*
|
2003-10-24 |
2006-07-12 |
Alza Corporation |
Preparation of lipid particles
|
|
US9050378B2
(en)
*
|
2003-12-10 |
2015-06-09 |
Board Of Regents, The University Of Texas System |
N2S2 chelate-targeting ligand conjugates
|
|
US20050191344A1
(en)
*
|
2004-01-15 |
2005-09-01 |
Samuel Zalipsky |
Liposome composition for delivery of therapeutic agents
|
|
US8168222B2
(en)
|
2004-09-07 |
2012-05-01 |
Board Of Regents Of The University Of Nebraska |
Amphiphilic polymer-protein conjugates and methods of use thereof
|
|
US8017151B2
(en)
*
|
2004-09-07 |
2011-09-13 |
Board Of Regents Of The University Of Nebraska By And Behalf Of The University Of Nebraska Medical Center |
Amphiphilic polymer-protein conjugates and methods of use thereof
|
|
WO2006042270A1
(en)
*
|
2004-10-08 |
2006-04-20 |
Alza Corporation |
Method of inserion of a lipid-linked moiety into a pre-formed lipid assembly using microwaves
|
|
CN103027893B
(zh)
*
|
2005-02-18 |
2014-11-12 |
国立大学法人德岛大学 |
含聚氧化烯链的脂质衍生物及含有该衍生物的脂质膜结构体
|
|
JP2006248978A
(ja)
*
|
2005-03-10 |
2006-09-21 |
Mebiopharm Co Ltd |
新規なリポソーム製剤
|
|
WO2006127360A2
(en)
*
|
2005-05-23 |
2006-11-30 |
Sdg, Inc. |
Lipid construct for delivery of interferon to a mammal
|
|
WO2007008300A2
(en)
|
2005-05-31 |
2007-01-18 |
ECOLE POLYTECHNIQUE FéDéRALE DE LAUSANNE |
Triblock copolymers for cytoplasmic delivery of gene-based drugs
|
|
ES2798263T3
(es)
|
2005-12-08 |
2020-12-10 |
Insmed Inc |
Composiciones a base de lípidos de antiinfecciosos para tratar infecciones pulmonares
|
|
WO2007092944A2
(en)
*
|
2006-02-08 |
2007-08-16 |
Introgen Therapeutics, Inc. |
Compositions and methods involving gene therapy and proteasome modulation
|
|
US8758723B2
(en)
|
2006-04-19 |
2014-06-24 |
The Board Of Regents Of The University Of Texas System |
Compositions and methods for cellular imaging and therapy
|
|
WO2007143659A2
(en)
|
2006-06-05 |
2007-12-13 |
Massachusetts Institute Of Technology |
Crosslinked, degradable polymers and uses thereof
|
|
US20080031883A1
(en)
*
|
2006-07-13 |
2008-02-07 |
Torchilin Vladimir P |
Condition-dependent, multiple target delivery system
|
|
US8343539B2
(en)
*
|
2006-07-14 |
2013-01-01 |
Regents Of The University Of Minnesota |
Compounds that bind α5β1 integrin and methods of use
|
|
CA2658768C
(en)
|
2006-07-21 |
2016-05-17 |
Massachusetts Institute Of Technology |
End-modified poly(beta-amino esters) and uses thereof
|
|
US20080213349A1
(en)
*
|
2006-09-11 |
2008-09-04 |
Deepak Ramesh Thakker |
Liposome Complexes Containing Pharmaceutical Agents and Methods
|
|
CA2699184A1
(en)
*
|
2006-09-22 |
2008-03-27 |
Labopharm Inc. |
Compositions and methods for ph targeted drug delivery
|
|
US10925977B2
(en)
*
|
2006-10-05 |
2021-02-23 |
Ceil>Point, LLC |
Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
|
|
US9119783B2
(en)
|
2007-05-07 |
2015-09-01 |
Insmed Incorporated |
Method of treating pulmonary disorders with liposomal amikacin formulations
|
|
WO2009006311A2
(en)
*
|
2007-06-29 |
2009-01-08 |
Wisconsin Alumni Research Foundation |
Structuring effect of cholesterol in peg-phospholipid micelles, drug delivery of amphotericin b, and combination antifungals
|
|
WO2009091531A2
(en)
*
|
2008-01-16 |
2009-07-23 |
The General Hospital Corporation |
Uniform-sized, multi-drug carrying and photosensitive liposomes for advance drug delivery
|
|
WO2009154688A1
(en)
*
|
2008-05-28 |
2009-12-23 |
President And Fellows Of Harvard College |
A pre-fabricated electron microscopy grid for monolayer purification and methods and kits therefor
|
|
US8173621B2
(en)
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
|
JP5642673B2
(ja)
|
2008-07-10 |
2014-12-17 |
セリナ・セラピユーテイツクス・インコーポレーテツド |
不活性末端基を有するポリオキサゾリン類、保護された開始基から調製されるポリオキサゾリン類及び関連化合物
|
|
WO2010053572A2
(en)
|
2008-11-07 |
2010-05-14 |
Massachusetts Institute Of Technology |
Aminoalcohol lipidoids and uses thereof
|
|
EP2356228B1
(en)
|
2008-11-25 |
2023-05-03 |
École Polytechnique Fédérale de Lausanne (EPFL) |
Block copolymers and uses thereof
|
|
US8551973B2
(en)
|
2008-12-23 |
2013-10-08 |
Gilead Pharmasset Llc |
Nucleoside analogs
|
|
EP2376515A1
(en)
|
2008-12-23 |
2011-10-19 |
Pharmasset, Inc. |
Synthesis of purine nucleosides
|
|
CA2748057C
(en)
|
2008-12-23 |
2018-07-03 |
Pharmasset, Inc. |
Nucleoside phosphoramidates
|
|
EP2230515B1
(en)
*
|
2009-03-16 |
2014-12-17 |
Agilent Technologies, Inc. |
Passivation of surfaces after ligand coupling
|
|
CA2760776C
(en)
|
2009-05-05 |
2019-07-09 |
Alnylam Pharmaceuticals, Inc. |
Lipid compositions for the delivery of therapeutic agents
|
|
TWI598358B
(zh)
|
2009-05-20 |
2017-09-11 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
|
US9937128B2
(en)
|
2009-08-03 |
2018-04-10 |
The University Of North Carolina At Chapel Hill |
Liposomes comprising a calcium phosphate-containing precipitate
|
|
EP3150194A1
(en)
|
2009-08-31 |
2017-04-05 |
NanoCarrier Co., Ltd. |
Particle composition and medicinal composition comprising same
|
|
ME03091B
(me)
|
2009-12-01 |
2019-01-20 |
Translate Bio Inc |
Isporuka irnk za povećanje ekspresije proteina i enzima u humanim genetskim oboljenjima
|
|
JP4829351B2
(ja)
|
2010-02-05 |
2011-12-07 |
ナノキャリア株式会社 |
易崩壊型ポリマーミセル組成物
|
|
PL3290428T3
(pl)
|
2010-03-31 |
2022-02-07 |
Gilead Pharmasset Llc |
Tabletka zawierająca krystaliczny (S)-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-diokso-3,4-dihydropirymidyn-1(2H)-ylo)-4-fluoro-3-hydroksy-4-metylotetrahydrofuran-2-ylo)metoksy)(fenoksy)fosforylo)amino)propanian izopropylu
|
|
UY33312A
(es)
|
2010-03-31 |
2011-10-31 |
Pharmasset Inc |
Fosforamidato de nucleosido de purina
|
|
CL2011000718A1
(es)
|
2010-03-31 |
2012-04-09 |
Gilead Pharmasset Llc |
Proceso para la preparacion de compuestos fosforados enantiomericos.
|
|
EP2566512A1
(en)
|
2010-05-04 |
2013-03-13 |
Merrimack Pharmaceuticals, Inc. |
Antibodies against epidermal growth factor receptor (egfr) and uses thereof
|
|
CN103153283B
(zh)
|
2010-06-19 |
2017-05-17 |
健康科学西部大学 |
Peg化脂质体包封的糖肽抗生素的新制剂
|
|
US9193827B2
(en)
|
2010-08-26 |
2015-11-24 |
Massachusetts Institute Of Technology |
Poly(beta-amino alcohols), their preparation, and uses thereof
|
|
DK2632472T3
(en)
|
2010-10-29 |
2018-03-19 |
Sirna Therapeutics Inc |
RNA INTERFERENCE-MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERRING NUCLEIC ACIDS (SINA)
|
|
PT3042910T
(pt)
|
2010-11-30 |
2019-04-16 |
Gilead Pharmasset Llc |
2'-espiro-nucleósidos para utilização na terapia da hepatite c
|
|
US9238716B2
(en)
|
2011-03-28 |
2016-01-19 |
Massachusetts Institute Of Technology |
Conjugated lipomers and uses thereof
|
|
ES2762224T3
(es)
*
|
2011-05-12 |
2020-05-22 |
Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd |
Liposomas que comprenden lípidos conjugados con polímero y usos relacionados
|
|
US8691231B2
(en)
|
2011-06-03 |
2014-04-08 |
Merrimack Pharmaceuticals, Inc. |
Methods of treatment of tumors expressing predominantly high affinity EGFR ligands or tumors expressing predominantly low affinity EGFR ligands with monoclonal and oligoclonal anti-EGFR antibodies
|
|
PT2717893T
(pt)
|
2011-06-08 |
2019-08-20 |
Translate Bio Inc |
Composições de nanopartículas lipídicas e métodos para transferência de arnm
|
|
US8883989B2
(en)
|
2011-10-18 |
2014-11-11 |
Regents Of The University Of Minnesota |
Fractalkine binding polynucleotides and methods of use
|
|
MX363734B
(es)
|
2011-10-27 |
2019-03-29 |
Massachusetts Inst Technology |
Derivados de aminoacidos funcionalizados en la terminal n capaces de formar microesferas encapsuladoras de farmaco.
|
|
US20150267192A1
(en)
|
2012-06-08 |
2015-09-24 |
Shire Human Genetic Therapies, Inc. |
Nuclease resistant polynucleotides and uses thereof
|
|
WO2014015016A1
(en)
|
2012-07-18 |
2014-01-23 |
Onyx Therapeutics, Inc. |
Liposomal compositions of epoxyketone-based proteasome inhibitors
|
|
CN102920658B
(zh)
*
|
2012-11-02 |
2015-01-21 |
艾韦特(溧阳)医药科技有限公司 |
与glp-1类似物和聚乙二醇结合的脂质体及其制备方法
|
|
WO2014085526A1
(en)
|
2012-11-29 |
2014-06-05 |
Insmed Incorporated |
Stabilized vancomycin formulations
|
|
US20140271822A1
(en)
*
|
2013-03-13 |
2014-09-18 |
Mallinckrodt Llc |
Modified docetaxel liposome formulations
|
|
KR20150128687A
(ko)
|
2013-03-14 |
2015-11-18 |
샤이어 휴먼 지네틱 테라피즈 인크. |
메신저 rna의 정제 방법
|
|
CA2904151C
(en)
|
2013-03-14 |
2023-09-12 |
Shire Human Genetic Therapies, Inc. |
Cftr mrna compositions and related methods and uses
|
|
US10711106B2
(en)
|
2013-07-25 |
2020-07-14 |
The University Of Chicago |
High aspect ratio nanofibril materials
|
|
BR112016009014B1
(pt)
|
2013-10-22 |
2024-02-06 |
Translate Bio, Inc |
USO DE COMPOSIÇÃO COMPREENDENDO mRNA PARA DEFICIÊNCIA DE ARGININOSSUCINATO SINTETASE
|
|
EA201992208A1
(ru)
|
2013-10-22 |
2020-07-31 |
Транслейт Био, Инк. |
ЛЕЧЕНИЕ ФЕНИЛКЕТОНУРИИ С ПРИМЕНЕНИЕМ мРНК
|
|
WO2015061467A1
(en)
|
2013-10-22 |
2015-04-30 |
Shire Human Genetic Therapies, Inc. |
Lipid formulations for delivery of messenger rna
|
|
EP3071515A2
(en)
|
2013-11-18 |
2016-09-28 |
Rubius Therapeutics, Inc. |
Synthetic membrane-receiver complexes
|
|
JP2017510542A
(ja)
|
2014-01-31 |
2017-04-13 |
ファクター バイオサイエンス インコーポレイテッド |
核酸生成及び送達のための方法及び製品
|
|
US20170173005A1
(en)
|
2014-03-27 |
2017-06-22 |
Research Foundation Of The City University Of New York |
Method for detecting or treating triple negative breast cancer
|
|
HUE054471T2
(hu)
|
2014-04-01 |
2021-09-28 |
Rubius Therapeutics Inc |
Immunmodulációs módszerek és készítmények
|
|
KR102739894B1
(ko)
|
2014-04-25 |
2024-12-05 |
샤이어 휴먼 지네틱 테라피즈 인크. |
메신저 rna 의 정제 방법
|
|
PL3142643T3
(pl)
|
2014-05-15 |
2019-12-31 |
Insmed Incorporated |
Sposoby leczenia zakażeń płuc prątkami niegruźliczymi
|
|
US10022455B2
(en)
|
2014-05-30 |
2018-07-17 |
Translate Bio, Inc. |
Biodegradable lipids for delivery of nucleic acids
|
|
AU2015279968B2
(en)
|
2014-06-24 |
2019-11-14 |
Translate Bio, Inc. |
Stereochemically enriched compositions for delivery of nucleic acids
|
|
WO2016004202A1
(en)
|
2014-07-02 |
2016-01-07 |
Massachusetts Institute Of Technology |
Polyamine-fatty acid derived lipidoids and uses thereof
|
|
CN104546722B
(zh)
*
|
2015-02-10 |
2017-05-24 |
中国医学科学院医药生物技术研究所 |
米铂脂质体和制法
|
|
EP3543339A1
(en)
|
2015-02-13 |
2019-09-25 |
Factor Bioscience Inc. |
Nucleic acid products and methods of administration thereof
|
|
CA2990172A1
(en)
|
2015-06-19 |
2016-12-22 |
Massachusetts Institute Of Technology |
Alkenyl substituted 2,5-piperazinediones and their use in compositions for delivering an agent to a subject or cell
|
|
CN107920964B
(zh)
|
2015-07-09 |
2022-02-25 |
加利福尼亚大学董事会 |
融合脂质体包被的多孔硅纳米颗粒
|
|
WO2017048860A1
(en)
|
2015-09-14 |
2017-03-23 |
Vgsk Technologies, Inc. |
A sterically stabilized carrier for subcutaneous, sublingual and oral therapeutics, compositions and methods for treating a mammal
|
|
US10583083B1
(en)
|
2016-08-10 |
2020-03-10 |
Verily Life Sciences Llc |
ROS-responsive multilamellar liposomal vesicles for targeting inflammatory macrophages
|
|
US10517823B1
(en)
*
|
2016-08-10 |
2019-12-31 |
Verily Life Sciences Llc |
ROS—responsive liposomes for specific targeting
|
|
CA3033788A1
(en)
|
2016-08-17 |
2018-02-22 |
Factor Bioscience Inc. |
Nucleic acid products and methods of administration thereof
|
|
EP3538546B1
(en)
|
2016-11-14 |
2025-01-08 |
Novartis AG |
Compositions, methods, and therapeutic uses related to fusogenic protein minion
|
|
MX2019010155A
(es)
|
2017-02-27 |
2020-12-10 |
Translate Bio Inc |
Arnm de cftr optimizado por codón novedoso.
|
|
EP3595636A4
(en)
|
2017-03-16 |
2021-01-13 |
Children's Medical Center Corporation |
ENGINEERED LIPOSOMES USED AS THERAPEUTIC AGENTS TARGETING CANCER
|
|
JP2020517750A
(ja)
*
|
2017-04-19 |
2020-06-18 |
エイピーエイ− アドバンスト・テクノロジーズ・リミテッドＡｐａ− Ａｄｖａｎｃｅｄ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｌｔｄ． |
癌処置のための融合性リポソーム、組成物、キットおよびその使用
|
|
WO2018213476A1
(en)
|
2017-05-16 |
2018-11-22 |
Translate Bio, Inc. |
Treatment of cystic fibrosis by delivery of codon-optimized mrna encoding cftr
|
|
WO2019084229A1
(en)
|
2017-10-27 |
2019-05-02 |
Massachusetts Institute Of Technology |
Poly (beta-amino esters) and uses thereof
|
|
EP3773505A4
(en)
|
2018-03-30 |
2021-12-22 |
Insmed Incorporated |
PROCESS FOR THE CONTINUOUS MANUFACTURING OF LIPOSOMAL MEDICINAL PRODUCTS
|
|
AU2019262117C1
(en)
|
2018-05-02 |
2024-12-05 |
Insmed Incorporated |
Methods for the manufacture of liposomal drug formulations
|
|
WO2020041793A1
(en)
|
2018-08-24 |
2020-02-27 |
Translate Bio, Inc. |
Methods for purification of messenger rna
|
|
WO2020084623A2
(en)
*
|
2018-10-24 |
2020-04-30 |
Apa- Advanced Technologies Ltd. |
Fusogenic liposomes for selective imaging of tumor cells
|
|
CA3117781A1
(en)
|
2018-10-26 |
2020-04-30 |
Massachusetts Institute Of Technology |
Polymer-lipids and compositions
|
|
MX2021005969A
(es)
|
2018-11-21 |
2021-09-14 |
Translate Bio Inc |
Tratamiento de la fibrosis quística mediante el suministro de arnm que codifica cftr nebulizado.
|
|
US12433847B2
(en)
|
2021-03-09 |
2025-10-07 |
Massachusetts Institute Of Technology |
Branched poly(-amino esters) for the delivery of nucleic acids
|
|
AU2022270670A1
(en)
|
2021-05-05 |
2023-11-30 |
Nejat Duzgunes |
Liposome-encapsulated corticosteriods inhibit sars-cov-2 replication and reduces lung inflammation
|
|
JPWO2023210671A1
(enExample)
*
|
2022-04-26 |
2023-11-02 |
|
|