JP2001502163A - 血小板活性化因子アセチルヒドロラーゼ - Google Patents

血小板活性化因子アセチルヒドロラーゼ

Info

Publication number
JP2001502163A
JP2001502163A JP10509976A JP50997698A JP2001502163A JP 2001502163 A JP2001502163 A JP 2001502163A JP 10509976 A JP10509976 A JP 10509976A JP 50997698 A JP50997698 A JP 50997698A JP 2001502163 A JP2001502163 A JP 2001502163A
Authority
JP
Japan
Prior art keywords
paf
activity
fragment
rph
buffer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10509976A
Other languages
English (en)
Japanese (ja)
Inventor
コーセンズ,ローレンス,エス.
エバーハード,クリスティン,ディー.
グレイ,パトリック
トロン,ハイ,レ
トエルカー,ラリー,ダブリュ.
ワイルダー,シェリル,エル.
Original Assignee
アイコス コーポレイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アイコス コーポレイション filed Critical アイコス コーポレイション
Publication of JP2001502163A publication Critical patent/JP2001502163A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/01Carboxylic ester hydrolases (3.1.1)
    • C12Y301/010471-Alkyl-2-acetylglycerophosphocholine esterase (3.1.1.47), i.e. platelet-activating factor acetylhydrolase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP10509976A 1997-08-13 1997-08-13 血小板活性化因子アセチルヒドロラーゼ Pending JP2001502163A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1997/014212 WO1999009147A1 (en) 1997-08-13 1997-08-13 Truncated platelet-activating factor acetylhydrolase

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008173182A Division JP2009005705A (ja) 2008-07-02 2008-07-02 血小板活性化因子アセチルヒドロラーゼ

Publications (1)

Publication Number Publication Date
JP2001502163A true JP2001502163A (ja) 2001-02-20

Family

ID=22261441

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10509976A Pending JP2001502163A (ja) 1997-08-13 1997-08-13 血小板活性化因子アセチルヒドロラーゼ

Country Status (12)

Country Link
EP (1) EP0948605A1 (hu)
JP (1) JP2001502163A (hu)
AU (1) AU751594B2 (hu)
BR (1) BR9711882A (hu)
CA (1) CA2267994C (hu)
CZ (1) CZ297603B6 (hu)
HU (1) HUP9903959A3 (hu)
IL (3) IL129262A0 (hu)
NO (1) NO326968B1 (hu)
PL (1) PL190532B1 (hu)
SK (1) SK286518B6 (hu)
WO (1) WO1999009147A1 (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69423436T2 (de) 1993-06-25 2000-09-07 Smithkline Beecham P.L.C., Brentford An lipoprotein gebundene phospholipase a2, inhibitoren davon und deren verwendung für diagnose und therapie
AU2953201A (en) * 2000-01-20 2001-07-31 Genome Therapeutics Corporation Rapid determination of gene structure using cdna sequence
CN103891709A (zh) * 2012-12-24 2014-07-02 深圳先进技术研究院 细胞冻存液及细胞冻存方法
CN112575057B (zh) * 2020-12-11 2021-07-30 深圳上泰生物工程有限公司 一种组合物及其在检测脂蛋白相关磷脂酶a2活性中的应用
WO2022120784A1 (zh) * 2020-12-11 2022-06-16 深圳上泰生物工程有限公司 一种组合物及其在检测脂蛋白相关磷脂酶a2活性中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69423436T2 (de) * 1993-06-25 2000-09-07 Smithkline Beecham P.L.C., Brentford An lipoprotein gebundene phospholipase a2, inhibitoren davon und deren verwendung für diagnose und therapie
ATE201905T1 (de) * 1993-10-06 2001-06-15 Icos Corp Acethylhydrolase des plättchen aktivierenden faktors
EP0853673A1 (en) * 1995-09-29 1998-07-22 Smithkline Beecham Plc COMPOUND HAVING SEQUENCE HOMOLOGY WITH LIPOPROTEIN ASSOCIATED PHOSPHOLIPASE A2 (Lp-PLA2)/PAF ACETYL HYDROLASE
WO1997012963A2 (en) * 1995-09-29 1997-04-10 Smithkline Beecham Plc A paf-acetylhydrolase and use in therapy

Also Published As

Publication number Publication date
IL173867A0 (en) 2006-07-05
CZ297603B6 (cs) 2007-02-07
IL129262A0 (en) 2000-02-17
NO991717D0 (no) 1999-04-12
PL190532B1 (pl) 2005-12-30
CA2267994A1 (en) 1999-02-25
EP0948605A1 (en) 1999-10-13
CZ124199A3 (cs) 2000-06-14
HUP9903959A3 (en) 2002-01-28
BR9711882A (pt) 1999-09-21
AU3978297A (en) 1999-03-08
PL332833A1 (en) 1999-10-11
SK286518B6 (sk) 2008-12-05
NO326968B1 (no) 2009-03-23
NO991717L (no) 1999-06-11
IL129262A (en) 2006-06-11
AU751594B2 (en) 2002-08-22
CA2267994C (en) 2005-04-12
SK47399A3 (en) 2000-11-07
HUP9903959A2 (hu) 2000-03-28
WO1999009147A1 (en) 1999-02-25

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