JP2001501104A - その表面を、酸化窒素放出ニトロシル含有有機金属化合物でコートされたポリマーによる、外来物に曝された血液血小板凝固の阻害およびこのようにコートされた外来物 - Google Patents

その表面を、酸化窒素放出ニトロシル含有有機金属化合物でコートされたポリマーによる、外来物に曝された血液血小板凝固の阻害およびこのようにコートされた外来物

Info

Publication number
JP2001501104A
JP2001501104A JP10511854A JP51185498A JP2001501104A JP 2001501104 A JP2001501104 A JP 2001501104A JP 10511854 A JP10511854 A JP 10511854A JP 51185498 A JP51185498 A JP 51185498A JP 2001501104 A JP2001501104 A JP 2001501104A
Authority
JP
Japan
Prior art keywords
blood
coating
nitrosyl
polymer
coated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP10511854A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001501104A5 (enExample
Inventor
ハーゾグ，ウィリアム・アール・ジュニア
ポウ，ソビティジ
ローゼン，ジェラルド・エム
ザオ，イ―ジュ
Original Assignee
ノボ・バスク・インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ノボ・バスク・インコーポレイテッド filed Critical ノボ・バスク・インコーポレイテッド
Publication of JP2001501104A publication Critical patent/JP2001501104A/ja
Publication of JP2001501104A5 publication Critical patent/JP2001501104A5/ja
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/02—Use of inorganic materials
    • A61L33/027—Other specific inorganic materials not covered by A61L33/022 or A61L33/025
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/924—Material characteristic
    • Y10S623/926—Synthetic

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • External Artificial Organs (AREA)
JP10511854A 1996-08-27 1997-08-27 その表面を、酸化窒素放出ニトロシル含有有機金属化合物でコートされたポリマーによる、外来物に曝された血液血小板凝固の阻害およびこのようにコートされた外来物 Ceased JP2001501104A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/703,646 US5797887A (en) 1996-08-27 1996-08-27 Medical device with a surface adapted for exposure to a blood stream which is coated with a polymer containing a nitrosyl-containing organo-metallic compound which releases nitric oxide from the coating to mediate platelet aggregation
US08/703,646 1996-08-27
PCT/US1997/015022 WO1998008482A2 (en) 1996-08-27 1997-08-27 Polymeric coating for a surface exposed to blood

Publications (2)

Publication Number Publication Date
JP2001501104A true JP2001501104A (ja) 2001-01-30
JP2001501104A5 JP2001501104A5 (enExample) 2005-07-14

Family

ID=24826237

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10511854A Ceased JP2001501104A (ja) 1996-08-27 1997-08-27 その表面を、酸化窒素放出ニトロシル含有有機金属化合物でコートされたポリマーによる、外来物に曝された血液血小板凝固の阻害およびこのようにコートされた外来物

Country Status (8)

Country Link
US (2) US5797887A (enExample)
EP (1) EP0975274A4 (enExample)
JP (1) JP2001501104A (enExample)
AU (1) AU733616B2 (enExample)
CA (1) CA2264564A1 (enExample)
IL (1) IL128739A (enExample)
NZ (1) NZ334392A (enExample)
WO (1) WO1998008482A2 (enExample)

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CA2264564A1 (en) 1998-03-05
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IL128739A0 (en) 2000-01-31
NZ334392A (en) 2000-11-24
EP0975274A4 (en) 2004-05-19
IL128739A (en) 2004-06-01
AU4163297A (en) 1998-03-19
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US5797887A (en) 1998-08-25
US6656217B1 (en) 2003-12-02

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