CA2264564A1 - Inhibition of blood platelet aggregation in blood exposed to a foreign body by a polymer coating on the surface thereof containing a nitric oxide-releasing nitrosyl-containing organometallic compound and foreign bodies thus coated - Google Patents
Inhibition of blood platelet aggregation in blood exposed to a foreign body by a polymer coating on the surface thereof containing a nitric oxide-releasing nitrosyl-containing organometallic compound and foreign bodies thus coated Download PDFInfo
- Publication number
- CA2264564A1 CA2264564A1 CA002264564A CA2264564A CA2264564A1 CA 2264564 A1 CA2264564 A1 CA 2264564A1 CA 002264564 A CA002264564 A CA 002264564A CA 2264564 A CA2264564 A CA 2264564A CA 2264564 A1 CA2264564 A1 CA 2264564A1
- Authority
- CA
- Canada
- Prior art keywords
- blood
- coating
- nitric oxide
- living
- polymer coating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/02—Use of inorganic materials
- A61L33/027—Other specific inorganic materials not covered by A61L33/022 or A61L33/025
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/085—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
- A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/924—Material characteristic
- Y10S623/926—Synthetic
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Inorganic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Materials For Medical Uses (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/703,646 US5797887A (en) | 1996-08-27 | 1996-08-27 | Medical device with a surface adapted for exposure to a blood stream which is coated with a polymer containing a nitrosyl-containing organo-metallic compound which releases nitric oxide from the coating to mediate platelet aggregation |
| US08/703,646 | 1996-08-27 | ||
| PCT/US1997/015022 WO1998008482A2 (en) | 1996-08-27 | 1997-08-27 | Polymeric coating for a surface exposed to blood |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2264564A1 true CA2264564A1 (en) | 1998-03-05 |
Family
ID=24826237
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002264564A Abandoned CA2264564A1 (en) | 1996-08-27 | 1997-08-27 | Inhibition of blood platelet aggregation in blood exposed to a foreign body by a polymer coating on the surface thereof containing a nitric oxide-releasing nitrosyl-containing organometallic compound and foreign bodies thus coated |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5797887A (enExample) |
| EP (1) | EP0975274A4 (enExample) |
| JP (1) | JP2001501104A (enExample) |
| AU (1) | AU733616B2 (enExample) |
| CA (1) | CA2264564A1 (enExample) |
| IL (1) | IL128739A (enExample) |
| NZ (1) | NZ334392A (enExample) |
| WO (1) | WO1998008482A2 (enExample) |
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| US5207706A (en) * | 1988-10-05 | 1993-05-04 | Menaker M D Gerald | Method and means for gold-coating implantable intravascular devices |
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| US5380758A (en) * | 1991-03-29 | 1995-01-10 | Brigham And Women's Hospital | S-nitrosothiols as smooth muscle relaxants and therapeutic uses thereof |
| ES2112332T3 (es) * | 1991-09-24 | 1998-04-01 | Us Health | Derivados de substitucion de oxigeno de productos de adicion de nucleofilo-oxido nitrico utilizados como promedicamentos donadores de oxido nitrico. |
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| US5405919A (en) * | 1992-08-24 | 1995-04-11 | The United States Of America As Represented By The Secretary Of Health And Human Services | Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biological disorders |
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1996
- 1996-08-27 US US08/703,646 patent/US5797887A/en not_active Expired - Fee Related
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1997
- 1997-08-27 WO PCT/US1997/015022 patent/WO1998008482A2/en not_active Ceased
- 1997-08-27 IL IL12873997A patent/IL128739A/en not_active IP Right Cessation
- 1997-08-27 CA CA002264564A patent/CA2264564A1/en not_active Abandoned
- 1997-08-27 EP EP97939571A patent/EP0975274A4/en not_active Withdrawn
- 1997-08-27 JP JP10511854A patent/JP2001501104A/ja not_active Ceased
- 1997-08-27 AU AU41632/97A patent/AU733616B2/en not_active Ceased
- 1997-08-27 NZ NZ334392A patent/NZ334392A/xx unknown
- 1997-08-27 US US09/254,002 patent/US6656217B1/en not_active Expired - Fee Related
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| AU4163297A (en) | 1998-03-19 |
| IL128739A0 (en) | 2000-01-31 |
| WO1998008482A3 (en) | 1998-04-23 |
| WO1998008482A2 (en) | 1998-03-05 |
| IL128739A (en) | 2004-06-01 |
| US6656217B1 (en) | 2003-12-02 |
| US5797887A (en) | 1998-08-25 |
| EP0975274A4 (en) | 2004-05-19 |
| EP0975274A2 (en) | 2000-02-02 |
| NZ334392A (en) | 2000-11-24 |
| AU733616B2 (en) | 2001-05-17 |
| JP2001501104A (ja) | 2001-01-30 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued |