JP2000516257A5 - - Google Patents
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- Publication number
- JP2000516257A5 JP2000516257A5 JP1998533609A JP53360998A JP2000516257A5 JP 2000516257 A5 JP2000516257 A5 JP 2000516257A5 JP 1998533609 A JP1998533609 A JP 1998533609A JP 53360998 A JP53360998 A JP 53360998A JP 2000516257 A5 JP2000516257 A5 JP 2000516257A5
- Authority
- JP
- Japan
- Prior art keywords
- page
- line
- formula
- aspirin
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 description 7
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 4
- 102000003141 Tachykinin Human genes 0.000 description 4
- 229960001138 acetylsalicylic acid Drugs 0.000 description 4
- 239000005557 antagonist Substances 0.000 description 4
- 108060008037 tachykinin Proteins 0.000 description 4
- 239000002253 acid Substances 0.000 description 3
- 239000000730 antalgic agent Substances 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- QDZOEBFLNHCSSF-PFFBOGFISA-N (2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2R)-2-amino-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pentanediamide Chemical compound C([C@@H](C(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O)NC(=O)[C@@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](N)CCCNC(N)=N)C1=CC=CC=C1 QDZOEBFLNHCSSF-PFFBOGFISA-N 0.000 description 2
- 102100024304 Protachykinin-1 Human genes 0.000 description 2
- 101800003906 Substance P Proteins 0.000 description 2
- 229940035676 analgesics Drugs 0.000 description 2
- 239000012458 free base Substances 0.000 description 2
- 239000004530 micro-emulsion Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9700597.9A GB9700597D0 (en) | 1997-01-14 | 1997-01-14 | Organic compounds |
| GB9700597.9 | 1997-01-14 | ||
| PCT/EP1997/007307 WO1998031704A2 (en) | 1997-01-14 | 1997-12-29 | Tachykinin antagonists |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005344056A Division JP3817256B2 (ja) | 1997-01-14 | 2005-11-29 | タキキニンアンタゴニスト |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2000516257A JP2000516257A (ja) | 2000-12-05 |
| JP2000516257A5 true JP2000516257A5 (https=) | 2009-05-07 |
| JP4306804B2 JP4306804B2 (ja) | 2009-08-05 |
Family
ID=10805904
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP53360998A Expired - Fee Related JP4306804B2 (ja) | 1997-01-14 | 1997-12-29 | タキキニンアンタゴニスト |
| JP2005344056A Expired - Fee Related JP3817256B2 (ja) | 1997-01-14 | 2005-11-29 | タキキニンアンタゴニスト |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005344056A Expired - Fee Related JP3817256B2 (ja) | 1997-01-14 | 2005-11-29 | タキキニンアンタゴニスト |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6107293A (https=) |
| EP (1) | EP0964867B1 (https=) |
| JP (2) | JP4306804B2 (https=) |
| AR (1) | AR011521A1 (https=) |
| AT (1) | ATE290546T1 (https=) |
| AU (1) | AU5764298A (https=) |
| CA (1) | CA2278057C (https=) |
| CO (1) | CO4950614A1 (https=) |
| DE (1) | DE69732715T2 (https=) |
| ES (1) | ES2239368T3 (https=) |
| GB (1) | GB9700597D0 (https=) |
| PT (1) | PT964867E (https=) |
| WO (1) | WO1998031704A2 (https=) |
| ZA (1) | ZA98256B (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6426331B1 (en) | 1998-07-08 | 2002-07-30 | Tularik Inc. | Inhibitors of STAT function |
| GB9815696D0 (en) * | 1998-07-20 | 1998-09-16 | Pfizer Ltd | Heterocyclics |
| EP1158996A4 (en) | 1999-02-18 | 2005-01-12 | Kaken Pharma Co Ltd | NEW AMIDE SECRETAGOGUES OF GROWTH HORMONE DERIVATIVES |
| WO2001083517A1 (en) * | 2000-05-03 | 2001-11-08 | Tularik Inc. | Stat4 and stat6 binding dipeptide derivatives |
| US6884782B2 (en) | 2000-11-08 | 2005-04-26 | Amgen Inc. | STAT modulators |
| US20070219214A1 (en) * | 2006-02-01 | 2007-09-20 | Solvay Pharmaceuticals Gmbh | Dual NK2/NK3-antagonists, pharmaceutical compositions comprising them, and processes for their preparation |
| US8426386B2 (en) | 2006-10-16 | 2013-04-23 | Lion Corporation | NK1 receptor antagonist composition |
| WO2013004766A1 (en) | 2011-07-04 | 2013-01-10 | Ferrari Giulio | Nk-1 receptor antagonists for treating corneal neovascularisation |
| CN111918647A (zh) | 2018-02-26 | 2020-11-10 | 圣拉斐尔医院有限公司 | 用于治疗眼痛的nk-1拮抗剂 |
| WO2021180885A1 (en) | 2020-03-11 | 2021-09-16 | Ospedale San Raffaele S.R.L. | Treatment of stem cell deficiency |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ210669A (en) * | 1983-12-27 | 1988-05-30 | Syntex Inc | Benzoxazin-4-one derivatives and pharmaceutical compositions |
| GB8929070D0 (en) * | 1989-12-22 | 1990-02-28 | Fujisawa Pharmaceutical Co | Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same |
| FR2719312B1 (fr) * | 1994-04-28 | 1996-06-14 | Adir | Nouveau pseudopeptides dérivés de neurokinines, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
-
1997
- 1997-01-14 GB GBGB9700597.9A patent/GB9700597D0/en active Pending
- 1997-12-29 PT PT97953927T patent/PT964867E/pt unknown
- 1997-12-29 CA CA002278057A patent/CA2278057C/en not_active Expired - Fee Related
- 1997-12-29 US US09/341,626 patent/US6107293A/en not_active Expired - Lifetime
- 1997-12-29 AU AU57642/98A patent/AU5764298A/en not_active Abandoned
- 1997-12-29 WO PCT/EP1997/007307 patent/WO1998031704A2/en not_active Ceased
- 1997-12-29 JP JP53360998A patent/JP4306804B2/ja not_active Expired - Fee Related
- 1997-12-29 AT AT97953927T patent/ATE290546T1/de not_active IP Right Cessation
- 1997-12-29 DE DE69732715T patent/DE69732715T2/de not_active Expired - Lifetime
- 1997-12-29 ES ES97953927T patent/ES2239368T3/es not_active Expired - Lifetime
- 1997-12-29 EP EP97953927A patent/EP0964867B1/en not_active Expired - Lifetime
-
1998
- 1998-01-09 AR ARP980100097A patent/AR011521A1/es active IP Right Grant
- 1998-01-13 CO CO98001002A patent/CO4950614A1/es unknown
- 1998-01-13 ZA ZA98256A patent/ZA98256B/xx unknown
-
2005
- 2005-11-29 JP JP2005344056A patent/JP3817256B2/ja not_active Expired - Fee Related
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