JP2000512652A5 - - Google Patents

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Publication number: JP2000512652A5
Authority: JP; Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

JP1998502317A

Other languages

English (en)

Other versions

JP2000512652A (ja

Filing date

1997-06-20

Publication date

2005-02-10

1996-06-20 Priority claimed from DE19624668A external-priority patent/DE19624668A1/de

1997-06-20 Application filed filed Critical

2000-09-26 Publication of JP2000512652A publication Critical patent/JP2000512652A/ja

2005-02-10 Publication of JP2000512652A5 publication Critical patent/JP2000512652A5/ja

Status Withdrawn legal-status Critical Current

Description

JP10502317A 1996-06-20 1997-06-20 腫瘍の治療または免疫抑制におけるピリジルアルカン、ピリジルアルケンおよび／またはピリジルアルキン酸アミド類の用途 Withdrawn JP2000512652A (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE19624668A DE19624668A1 (de)	1996-06-20	1996-06-20	Verwendung von Pyridylalkan-, Pyridylalken- bzw. Pyridylalkinsäureamiden
DE19624668.7		1996-06-20
PCT/EP1997/003244 WO1997048397A1 (en)	1996-06-20	1997-06-20	Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression

Publications (2)

Publication Number	Publication Date
JP2000512652A JP2000512652A (ja)	2000-09-26
JP2000512652A5 true JP2000512652A5 (ja)	2005-02-10

Family

ID=7797502

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP10502317A Withdrawn JP2000512652A (ja)	1996-06-20	1997-06-20	腫瘍の治療または免疫抑制におけるピリジルアルカン、ピリジルアルケンおよび／またはピリジルアルキン酸アミド類の用途

Country Status (10)

Country	Link
EP (1)	EP0912176B1 (ja)
JP (1)	JP2000512652A (ja)
AT (1)	ATE224713T1 (ja)
AU (1)	AU3262497A (ja)
DE (2)	DE19624668A1 (ja)
DK (1)	DK0912176T3 (ja)
ES (1)	ES2181006T3 (ja)
PT (1)	PT912176E (ja)
WO (1)	WO1997048397A1 (ja)
ZA (1)	ZA975443B (ja)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19624659A1 (de)	1996-06-20	1998-01-08	Klinge Co Chem Pharm Fab	Neue Pyridylalken- und Pyridylalkinsäureamide
US6451816B1 (en)	1997-06-20	2002-09-17	Klinge Pharma Gmbh	Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression
JPH10338658A (ja) *	1997-04-08	1998-12-22	Hoechst Marion Roussel Kk	レチノイド作用調節剤
DE19756261A1 (de)	1997-12-17	1999-07-01	Klinge Co Chem Pharm Fab	Neue arylsubstituierte Pyridylalkan-, alken- und alkincarbonsäureamide
US6903118B1 (en)	1997-12-17	2005-06-07	Klinge Pharma Gmbh	Piperazinyl-substituted pyridylalkane, alkene and alkine carboxamides
DE19756212A1 (de)	1997-12-17	1999-07-01	Klinge Co Chem Pharm Fab	Neue, mit einem cyclischen Imid substituierte Pyridylalkan-, alken- und -alkincarbonsäureamide
DE19756235A1 (de)	1997-12-17	1999-07-01	Klinge Co Chem Pharm Fab	Neue piperidinylsubstituierte Pyridylalkan- alken- und -alkincarbonsäureamide
DE19818044A1 (de) *	1998-04-22	1999-10-28	Klinge Co Chem Pharm Fab	Verwendung von Vitamin-PP-Verbindungen
JP2002522499A (ja) *	1998-08-12	2002-07-23	スミスクライン・ビーチャム・コーポレイション	カルシウム分解化合物
DE19908483A1 (de) *	1999-02-26	2000-10-05	Klinge Co Chem Pharm Fab	Inhibitoren der zellulären Niacinamidmononucleotid-Bildung
EP1031564A1 (en) *	1999-02-26	2000-08-30	Klinge Pharma GmbH	Inhibitors of cellular nicotinamide mononucleotide formation and their use in cancer therapy
ES2228932T3 (es)	2000-08-11	2005-04-16	Wyeth	Procedimiento de tratamiento del carcinoma positivo de estrogenos.
CA2423251A1 (en)	2000-09-29	2002-04-04	Glaxo Group Limited	Morpholin-acetamide derivatives for the treatment of inflammatory diseases
EP1348434A1 (en) *	2002-03-27	2003-10-01	Fujisawa Deutschland GmbH	Use of pyridyl amides as inhibitors of angiogenesis
GB0207445D0 (en) *	2002-03-28	2002-05-08	Glaxo Group Ltd	Novel compounds
US7977049B2 (en)	2002-08-09	2011-07-12	President And Fellows Of Harvard College	Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms
KR100927915B1 (ko) *	2005-03-17	2009-11-19	화이자 인코포레이티드	통증 치료에 유용한 ｎ-(ｎ-설폰일아미노메틸)사이클로프로판카복사마이드 유도체
PE20071159A1 (es)	2005-10-31	2007-11-30	Schering Corp	Derivados de tropano 3-monosustituido como ligandos de receptores de nociceptina
US8067415B2 (en)	2005-11-01	2011-11-29	Millennium Pharmaceuticals, Inc.	Compounds useful as antagonists of CCR2
WO2007053498A1 (en)	2005-11-01	2007-05-10	Millennium Pharmaceuticals, Inc.	Compounds useful as antagonists of ccr2
HUP0600809A3 (en) *	2006-10-27	2008-09-29	Richter Gedeon Nyrt	New phenylsulfamoyl-benzamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them
EP2098231A1 (en)	2008-03-05	2009-09-09	Topotarget Switzerland SA	Use of NAD formation inhibitors for the treatment of ischemia-reperfusion injury
AU2009264273B2 (en)	2008-06-24	2015-01-22	Onxeo Dk, Branch Of Onxeo S.A., France	Squaric acid derivatives as inhibitors of the nicotinamide
JP5688367B2 (ja)	2008-08-29	2015-03-25	トポターゲット・アクティーゼルスカブＴｏｐｏＴａｒｇｅｔＡ／Ｓ	新規なウレアおよびチオウレア誘導体
US20120270900A1 (en)	2009-07-17	2012-10-25	Topo Target A/S	Novel method of treatment
WO2011121055A1 (en)	2010-03-31	2011-10-06	Topotarget A/S	Pyridinyl derivatives comprising a cyanoguanidine or squaric acid moiety
TW201217359A (en)	2010-09-03	2012-05-01	Forma Therapeutics Inc	Novel compounds and compositions for the inhibition of NAMPT
EP2611804A1 (en)	2010-09-03	2013-07-10	Forma TM, LLC.	Novel compounds and compositions for the inhibition of nampt
MX342838B (es)	2010-09-03	2016-10-14	Forma Tm Llc *	Compuestos y composiciones de guanidina para la inhibicion de nampt.
PL2621903T3 (pl) *	2010-09-29	2017-08-31	Intervet International B.V.	Związki n-heteroarylu
JP2013545750A (ja)	2010-11-15	2013-12-26	アッヴィ・インコーポレイテッド	Ｎａｍｐｔ阻害剤
SG10202010119TA (en)	2010-11-15	2020-11-27	Abbvie Inc	NAMPT And Rock Inhibitors
BR112013028281A2 (pt)	2011-05-04	2017-01-10	Forma Tm Llc	compostos e composições para inibição de nampt
MX347459B (es)	2011-05-09	2017-04-26	Forma Tm Llc	Nuevos compuestos y composiciones para la inhibición de nampt.
WO2013170118A1 (en)	2012-05-11	2013-11-14	Abbvie Inc.	Thiazolecarboxamide derivatives for use as nampt inhibitors
US8975398B2 (en)	2012-05-11	2015-03-10	Abbvie Inc.	NAMPT inhibitors
EP2852585A1 (en)	2012-05-11	2015-04-01	AbbVie Inc.	Nampt inhibitors
TW201350481A (zh)	2012-05-11	2013-12-16	Abbvie Inc	Ｎａｍｐｔ抑制劑
EP2925750A1 (en)	2012-11-29	2015-10-07	Karyopharm Therapeutics, Inc.	Substituted 2,3-dihydrobenzofuranyl compounds and uses thereof
KR102325247B1 (ko)	2013-07-03	2021-11-11	카리오팜 쎄라퓨틱스, 인코포레이티드	치환된 벤조퓨라닐 및 벤즈옥사졸릴 화합물 및 이의 용도
US9994558B2 (en)	2013-09-20	2018-06-12	Karyopharm Therapeutics Inc.	Multicyclic compounds and methods of using same
MX2018001979A (es)	2015-08-18	2019-04-25	Karyopharm Therapeutics Inc	(s,e) -3- (6-aminopiridin-3-il) -n- ( (5- (4- (3-fluoruro-3 metilpirrolidin-1-carbonil) fenil) -7- (4 fluorofenil) benzofuran-2-il)metil)acrilamida para el tratamiento del cancer.
WO2017117447A1 (en)	2015-12-31	2017-07-06	Karyopharm Therapeutics Inc.	Multicyclic compounds and uses thereof
AU2017345262A1 (en)	2016-10-18	2019-06-06	Seagen Inc.	Targeted delivery of nicotinamide adenine dinucleotide salvage pathway inhibitors
WO2018086703A1 (en)	2016-11-11	2018-05-17	Bayer Pharma Aktiengesellschaft	Dihydropyridazinones substituted with phenylureas
MA51189A (fr)	2017-04-27	2020-03-04	Seattle Genetics Inc	Conjugués d'inhibiteur de la voie de récupération du nicotinamide adénine dinucléotide quaternarisé
US20200360531A1 (en)	2018-01-31	2020-11-19	Bayer Aktiengesellschaft	Antibody drug conjugates (adcs) with nampt inhibitors
WO2021013693A1 (en)	2019-07-23	2021-01-28	Bayer Pharma Aktiengesellschaft	Antibody drug conjugates (adcs) with nampt inhibitors
CA3157315A1 (en)	2019-11-06	2021-05-14	Yushma Bhurruth-Alcor	Cancer treatments targeting cancer stem cells
JP2024518089A (ja)	2021-05-13	2024-04-24	リメディープラン，インコーポレーテッド	Ｎａｍｐｔ阻害剤とその使用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4778796A (en) *	1985-07-19	1988-10-18	Dainippon Pharmaceutical Co., Ltd.	ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same
JP2832979B2 (ja) *	1988-02-15	1998-12-09	武田薬品工業株式会社	不飽和カルボン酸アミド誘導体
EP0343307A1 (en) *	1988-05-26	1989-11-29	Fabrica Espanola De Productos Quimicos Y Farmaceuticos, S.A.	4-Piperidinealkanamine derivatives
CA2080127A1 (en) *	1990-04-10	1991-10-11	Peter Zimmermann	Pyridines as medicaments
AU7652391A (en) *	1990-04-10	1991-10-30	Byk Gulden Lomberg Chemische Fabrik Gmbh	Novel pyridine esters

1996
- 1996-06-20 DE DE19624668A patent/DE19624668A1/de not_active Ceased
1997
- 1997-06-19 ZA ZA9705443A patent/ZA975443B/xx unknown
- 1997-06-20 EP EP97928260A patent/EP0912176B1/en not_active Expired - Lifetime
- 1997-06-20 PT PT97928260T patent/PT912176E/pt unknown
- 1997-06-20 DE DE69715861T patent/DE69715861T2/de not_active Expired - Lifetime
- 1997-06-20 DK DK97928260T patent/DK0912176T3/da active
- 1997-06-20 AU AU32624/97A patent/AU3262497A/en not_active Abandoned
- 1997-06-20 AT AT97928260T patent/ATE224713T1/de active
- 1997-06-20 JP JP10502317A patent/JP2000512652A/ja not_active Withdrawn
- 1997-06-20 ES ES97928260T patent/ES2181006T3/es not_active Expired - Lifetime
- 1997-06-20 WO PCT/EP1997/003244 patent/WO1997048397A1/en active IP Right Grant

Publication	Publication Date	Title
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JP2000501771A5 (ja)	2004-08-19
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