JP2000512651A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2000512651A5 JP2000512651A5 JP1998502316A JP50231698A JP2000512651A5 JP 2000512651 A5 JP2000512651 A5 JP 2000512651A5 JP 1998502316 A JP1998502316 A JP 1998502316A JP 50231698 A JP50231698 A JP 50231698A JP 2000512651 A5 JP2000512651 A5 JP 2000512651A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19624704.7 | 1996-06-20 | ||
| DE19624704A DE19624704A1 (de) | 1996-06-20 | 1996-06-20 | Neue Pyridylalkansäureamide |
| PCT/EP1997/003243 WO1997048695A1 (en) | 1996-06-20 | 1997-06-20 | New pyridyl alkane acid amides as cytostatics and immunosuppressives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2000512651A JP2000512651A (ja) | 2000-09-26 |
| JP2000512651A5 true JP2000512651A5 (cg-RX-API-DMAC7.html) | 2005-02-10 |
| JP4225571B2 JP4225571B2 (ja) | 2009-02-18 |
Family
ID=7797525
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50231698A Expired - Fee Related JP4225571B2 (ja) | 1996-06-20 | 1997-06-20 | 細胞増殖抑制剤および免疫抑制剤としての新規なピリジルアルカン酸アミド類 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US6444823B1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP0934309B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4225571B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE223912T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU3342097A (cg-RX-API-DMAC7.html) |
| DE (2) | DE19624704A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK0934309T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2178779T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT934309E (cg-RX-API-DMAC7.html) |
| WO (1) | WO1997048695A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA975439B (cg-RX-API-DMAC7.html) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19624659A1 (de) | 1996-06-20 | 1998-01-08 | Klinge Co Chem Pharm Fab | Neue Pyridylalken- und Pyridylalkinsäureamide |
| DE19624704A1 (de) * | 1996-06-20 | 1998-01-08 | Klinge Co Chem Pharm Fab | Neue Pyridylalkansäureamide |
| US6451816B1 (en) | 1997-06-20 | 2002-09-17 | Klinge Pharma Gmbh | Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression |
| DE19756212A1 (de) * | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue, mit einem cyclischen Imid substituierte Pyridylalkan-, alken- und -alkincarbonsäureamide |
| DE19756235A1 (de) * | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue piperidinylsubstituierte Pyridylalkan- alken- und -alkincarbonsäureamide |
| US6903118B1 (en) | 1997-12-17 | 2005-06-07 | Klinge Pharma Gmbh | Piperazinyl-substituted pyridylalkane, alkene and alkine carboxamides |
| DE19756261A1 (de) | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue arylsubstituierte Pyridylalkan-, alken- und alkincarbonsäureamide |
| DE19818044A1 (de) * | 1998-04-22 | 1999-10-28 | Klinge Co Chem Pharm Fab | Verwendung von Vitamin-PP-Verbindungen |
| EP1031564A1 (en) * | 1999-02-26 | 2000-08-30 | Klinge Pharma GmbH | Inhibitors of cellular nicotinamide mononucleotide formation and their use in cancer therapy |
| DE19908483A1 (de) * | 1999-02-26 | 2000-10-05 | Klinge Co Chem Pharm Fab | Inhibitoren der zellulären Niacinamidmononucleotid-Bildung |
| US6172040B1 (en) * | 1999-05-28 | 2001-01-09 | A. Satyanarayan Naidu | Immobilized lactoferrin antimicrobial agents and the use thereof |
| BR0114323A (pt) | 2000-09-29 | 2003-07-01 | Glaxo Group Ltd | Composto ou um seu sal ou solvato farmaceuticamente aceitável, composição farmacêutica, uso do composto ou de um seu sal ou solvato farmaceuticamente aceitável, método de tratamento ou profilaxia de doenças inflamatórias, e, processo para preparar o composto |
| EP1348434A1 (en) * | 2002-03-27 | 2003-10-01 | Fujisawa Deutschland GmbH | Use of pyridyl amides as inhibitors of angiogenesis |
| CA2571710A1 (en) | 2004-06-24 | 2006-11-02 | Nicholas Valiante | Small molecule immunopotentiators and assays for their detection |
| AU2006224295A1 (en) | 2005-03-17 | 2006-09-21 | Pfizer, Inc. | N- (N-sulfonylaminomethyl) cyclopropanecarboxamide derivatives useful for the treatment of pain |
| US8067415B2 (en) | 2005-11-01 | 2011-11-29 | Millennium Pharmaceuticals, Inc. | Compounds useful as antagonists of CCR2 |
| WO2007053498A1 (en) | 2005-11-01 | 2007-05-10 | Millennium Pharmaceuticals, Inc. | Compounds useful as antagonists of ccr2 |
| EP1978963A2 (en) * | 2006-01-17 | 2008-10-15 | Merck & Co., Inc. | 2,5 diaza-bicycloý2.2.1¨heptane derivatives as calcium channel blockers |
| EP2098231A1 (en) | 2008-03-05 | 2009-09-09 | Topotarget Switzerland SA | Use of NAD formation inhibitors for the treatment of ischemia-reperfusion injury |
| WO2010023307A1 (en) | 2008-08-29 | 2010-03-04 | Topotarget A/S | Novel urea and thiourea derivatives |
| WO2010114907A1 (en) * | 2009-03-31 | 2010-10-07 | Vanderbilt University | Sulfonyl-azetidin-3-yl-methylamine amide analogs as glyt1 inhibitors, methods for making same, and use of same in treating psychiatric disorders |
| CA2768338A1 (en) | 2009-07-17 | 2011-01-20 | Topotarget A/S | Method for predicting the utility of administering nicotinic acid or a precursor or prodrug thereof to reduce the severity of side-effects of cancer treatment with nicotinamide phosphoribosyltransferase inhibitors |
| PH12013500412A1 (en) | 2010-09-03 | 2013-04-22 | Forma Tm Llc | Novel compounds and compositions for the inhibition of nampt |
| TW201216963A (en) | 2010-09-03 | 2012-05-01 | Forma Therapeutics Inc | Novel compounds and compositions for the inhibition of NAMPT |
| RU2016116533A (ru) | 2010-09-03 | 2018-11-30 | ФОРМА ТиЭм, ЭлЭлСИ | Новые соединения и композиции для ингибирования nampt |
| RU2616612C2 (ru) | 2011-05-04 | 2017-04-18 | ФОРМА ТиЭм, ЭлЭлСИ | Новые соединения и композиции для ингибирования nampt |
| RU2617643C2 (ru) | 2011-05-09 | 2017-04-25 | ФОРМА ТиЭм, ЭлЭлСИ | Новые соединения и композиции для ингибирования nampt |
| CN109776494B (zh) * | 2018-12-25 | 2021-06-18 | 中国人民解放军第二军医大学 | 一种多靶点抗肿瘤活性的烟酰胺磷酸核糖转移酶氮芥类抑制剂及其制备与应用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4283541A (en) | 1980-05-27 | 1981-08-11 | Usv Pharmaceutical Corporation | Pyridylacyl-hydroxamates |
| NL8005133A (nl) * | 1980-09-12 | 1982-04-01 | Duphar Int Res | Fenylpiperazinederivaten met antiagressieve werking. |
| JPS57136518A (en) * | 1981-02-18 | 1982-08-23 | Eisai Co Ltd | Immunoregulator |
| US5326772A (en) * | 1984-09-28 | 1994-07-05 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Diaryl compounds for their use |
| US4778796A (en) | 1985-07-19 | 1988-10-18 | Dainippon Pharmaceutical Co., Ltd. | ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same |
| DE3641822A1 (de) * | 1986-12-06 | 1988-06-16 | Goedecke Ag | Verwendung von dihydrophenylaminosaeurederivaten und diese enthaltende arzneimittel zur immunmodulation und cytostase |
| JPS63179869A (ja) * | 1987-01-20 | 1988-07-23 | Dainippon Pharmaceut Co Ltd | ピペリジン誘導体 |
| JP2832979B2 (ja) * | 1988-02-15 | 1998-12-09 | 武田薬品工業株式会社 | 不飽和カルボン酸アミド誘導体 |
| WO1989007443A1 (fr) | 1988-02-19 | 1989-08-24 | Byk Gulden Lomberg Chemische Fabrik Gmbh | R-(-)-niguldipine optiquement pure et ses derives pour traiter des affections tumorales |
| EP0343307A1 (en) * | 1988-05-26 | 1989-11-29 | Fabrica Espanola De Productos Quimicos Y Farmaceuticos, S.A. | 4-Piperidinealkanamine derivatives |
| IE903196A1 (en) * | 1989-09-05 | 1991-03-13 | Searle & Co | Substituted n-benzylpiperidine amides |
| IE903957A1 (en) * | 1989-11-06 | 1991-05-08 | Sanofi Sa | Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present |
| AU7652391A (en) * | 1990-04-10 | 1991-10-30 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Novel pyridine esters |
| CA2080127A1 (en) * | 1990-04-10 | 1991-10-11 | Peter Zimmermann | Pyridines as medicaments |
| US5260323A (en) * | 1990-06-28 | 1993-11-09 | Hoechst Aktiengesellschaft | 2,4- and 2,5-substituted pyridine-N-oxides, processes for their preparation and their use |
| DE4020570A1 (de) * | 1990-06-28 | 1992-01-02 | Hoechst Ag | 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung |
| US5244908A (en) * | 1990-07-30 | 1993-09-14 | Takeda Chemical Industries, Ltd. | Imidazopyridine derivatives and their pharmaceutical use |
| US5229400A (en) * | 1990-10-05 | 1993-07-20 | Ajinomoto Co., Inc. | Piperidine compounds and their use as antiarrhythmic agents |
| FR2676053B1 (fr) * | 1991-05-03 | 1993-08-27 | Sanofi Elf | Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| DE69209576D1 (de) * | 1991-05-10 | 1996-05-09 | Takeda Chemical Industries Ltd | Pyridinderivate, deren Herstellung und Anwendung |
| US5208247A (en) | 1991-08-01 | 1993-05-04 | American Cyanamid Company | Pyridinium compounds which are useful as antagonists of platelet activating factor |
| EP0548883A1 (de) * | 1991-12-24 | 1993-06-30 | Hoechst Aktiengesellschaft | Substituierte Pyridin-N-oxide, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
| US5622976A (en) | 1991-12-31 | 1997-04-22 | Fujisawa Pharmaceutical Co., Ltd. | Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity |
| GB9200535D0 (en) | 1992-01-10 | 1992-02-26 | Fujisawa Pharmaceutical Co | New compound |
| ZA947969B (en) | 1993-10-15 | 1996-07-12 | Schering Corp | Tricyclic sulfonamide compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| IL111235A (en) | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
| AU698313B2 (en) | 1994-03-14 | 1998-10-29 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Use of lipoxygenase inhibitors as anti-cancer therapeutic and intervention agents |
| FR2738245B1 (fr) * | 1995-08-28 | 1997-11-21 | Sanofi Sa | Nouveaux derives de piperidine, procede pour leur obtention et compositions pharmaceutiques les contenant |
| DE19624704A1 (de) * | 1996-06-20 | 1998-01-08 | Klinge Co Chem Pharm Fab | Neue Pyridylalkansäureamide |
| US6451816B1 (en) * | 1997-06-20 | 2002-09-17 | Klinge Pharma Gmbh | Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression |
-
1996
- 1996-06-20 DE DE19624704A patent/DE19624704A1/de not_active Ceased
-
1997
- 1997-06-19 ZA ZA9705439A patent/ZA975439B/xx unknown
- 1997-06-20 JP JP50231698A patent/JP4225571B2/ja not_active Expired - Fee Related
- 1997-06-20 DK DK97929240T patent/DK0934309T3/da active
- 1997-06-20 PT PT97929240T patent/PT934309E/pt unknown
- 1997-06-20 ES ES97929240T patent/ES2178779T3/es not_active Expired - Lifetime
- 1997-06-20 WO PCT/EP1997/003243 patent/WO1997048695A1/en not_active Ceased
- 1997-06-20 AU AU33420/97A patent/AU3342097A/en not_active Abandoned
- 1997-06-20 EP EP97929240A patent/EP0934309B1/en not_active Expired - Lifetime
- 1997-06-20 DE DE69715439T patent/DE69715439T2/de not_active Expired - Lifetime
- 1997-06-20 AT AT97929240T patent/ATE223912T1/de active
-
1998
- 1998-12-18 US US09/216,075 patent/US6444823B1/en not_active Expired - Fee Related
-
2002
- 2002-07-30 US US10/208,656 patent/US20040009967A1/en not_active Abandoned
-
2003
- 2003-10-10 US US10/683,509 patent/US7276524B2/en not_active Expired - Fee Related