JP2000511782A5 - - Google Patents

Download PDF

Info

Publication number
JP2000511782A5
JP2000511782A5 JP1998545569A JP54556998A JP2000511782A5 JP 2000511782 A5 JP2000511782 A5 JP 2000511782A5 JP 1998545569 A JP1998545569 A JP 1998545569A JP 54556998 A JP54556998 A JP 54556998A JP 2000511782 A5 JP2000511782 A5 JP 2000511782A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998545569A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000511782A (ja
JP4099239B2 (ja
Filing date
Publication date
Priority claimed from SE9701127A external-priority patent/SE9701127D0/xx
Application filed filed Critical
Publication of JP2000511782A publication Critical patent/JP2000511782A/ja
Publication of JP2000511782A5 publication Critical patent/JP2000511782A5/ja
Application granted granted Critical
Publication of JP4099239B2 publication Critical patent/JP4099239B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP54556998A 1997-03-26 1998-03-26 GALα1、3GALエピトープを有する抗原性融合タンパク質 Expired - Fee Related JP4099239B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9701127-4 1997-03-26
SE9701127A SE9701127D0 (sv) 1997-03-26 1997-03-26 Antigenic fusionprotein carrying GALal, 3GAL epitopes
PCT/SE1998/000555 WO1998042750A1 (en) 1997-03-26 1998-03-26 ANTIGENIC FUSIONPROTEIN CARRYING GALα1,3GAL EPITOPES

Publications (3)

Publication Number Publication Date
JP2000511782A JP2000511782A (ja) 2000-09-12
JP2000511782A5 true JP2000511782A5 (https=) 2005-11-10
JP4099239B2 JP4099239B2 (ja) 2008-06-11

Family

ID=20406335

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54556998A Expired - Fee Related JP4099239B2 (ja) 1997-03-26 1998-03-26 GALα1、3GALエピトープを有する抗原性融合タンパク質

Country Status (12)

Country Link
US (3) US6943239B2 (https=)
EP (2) EP0923606B1 (https=)
JP (1) JP4099239B2 (https=)
AT (1) ATE315047T1 (https=)
AU (1) AU751760B2 (https=)
BR (1) BR9804826A (https=)
CA (1) CA2255765A1 (https=)
DE (1) DE69833106T2 (https=)
DK (1) DK0923606T3 (https=)
ES (1) ES2258297T3 (https=)
SE (1) SE9701127D0 (https=)
WO (1) WO1998042750A1 (https=)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4421894B2 (ja) * 2001-07-20 2010-02-24 アブソーバー アクチボラゲット 血液型抗原融合ポリペプチドおよびその使用方法
WO2003089450A2 (en) * 2002-04-22 2003-10-30 Recopharma Ab Fusion polypeptides and methods for inhibiting microbial adhesion
JP2005530493A (ja) * 2002-04-22 2005-10-13 レコファーマ アーベー ムチン融合ポリペプチドワクチン、組成物およびそれらの使用方法
JP5183010B2 (ja) * 2002-05-16 2013-04-17 グリコミメティクス, インコーポレイテッド セレクチンによって媒介される機能を阻害するための化合物および方法
CA2490703A1 (en) * 2002-07-03 2004-01-15 Glycomimetics, Inc. Compositions and methods for diagnosis and therapy of medical conditions involving angiogenesis
EP1534748A2 (en) * 2002-08-09 2005-06-01 Recopharma AB Fusion proteins and methods of producing same
US20050076759A1 (en) * 2003-10-08 2005-04-14 Brian Westfall Linear saw with stab-cut bevel capability
US20040219158A1 (en) * 2003-05-02 2004-11-04 Glycomimetics, Inc. Compositions and methods for diagnosis and therapy of medical conditions involving infection with pseudomonas bacteria
WO2005047320A2 (en) * 2003-11-12 2005-05-26 Wisconsin Alumni Research Foundation Equine p-selection glycoprotein ligand-1 and uses thereof
US20050187171A1 (en) * 2003-11-19 2005-08-25 Glycomimetics, Inc. Glycomimetic antagonists for both E-and P-selectins
WO2005051920A2 (en) * 2003-11-19 2005-06-09 Glycomimetics, Inc. Specific antagonist for both e- and p-selectins
WO2006001348A1 (ja) * 2004-06-23 2006-01-05 Japan Science And Technology Agency 浸潤抑制及び細胞殺傷剤
US8201377B2 (en) * 2004-11-05 2012-06-19 Faus Group, Inc. Flooring system having multiple alignment points
US20090036386A1 (en) * 2005-05-25 2009-02-05 Glycomimetics, Inc Heterobifunctional compounds for selectin inhibition
EP1928892B1 (en) * 2005-08-09 2011-10-12 GlycoMimetics, Inc. Glycomimetic inhibitors of the pa-il lectin, pa-iil lectin or both the lectins from pseudomonas
SI2264043T1 (en) 2005-09-02 2018-01-31 Glycomimetics, Inc. HETEROBIFUNCTIONAL PAN-SELECTINE INHIBITORS
US20070113297A1 (en) * 2005-09-13 2007-05-17 Yongguang Yang Methods and compositions for inhibition of immune responses
EP2264060B1 (en) * 2006-01-26 2014-04-23 Recopharma AB Compositions and methods for inhibiting viral adhesion
US20070178447A1 (en) * 2006-01-31 2007-08-02 Bethyl Laboratories, Inc. Method for decreasing interference in results of immunochemical methods
WO2007143052A1 (en) * 2006-06-01 2007-12-13 Glycomimetics, Inc. Galactosides and thiodigalactosides as inhibitors of pa-il lectin from pseudomonas
WO2008060378A2 (en) 2006-10-12 2008-05-22 Glycomimetics, Inc. Glycomimetic replacements for hexoses and n-acetyl hexosamines
US7998486B2 (en) 2006-10-25 2011-08-16 Newlink Genetics Corporation Enhanced immunogenicity of tumor associated antigens by addition of alphaGal epitopes
AU2008216794A1 (en) * 2007-02-09 2008-08-21 Glycomimetics, Inc. Methods of use of glycomimetics with replacements for hexoses and N-acetyl hexosamines
US8039442B2 (en) * 2007-07-18 2011-10-18 Glycomimetics, Inc. Compounds and methods for treatment of sickle cell disease or complications associated therewith
WO2009126556A1 (en) * 2008-04-08 2009-10-15 Glycomimetics, Inc. Pan-selectin inhibitor with enhanced pharmacokinetic activity
CN102088983B (zh) * 2008-06-13 2013-01-30 糖模拟物有限公司 利用选择的糖模拟化合物的血液癌症的治疗
WO2010126888A1 (en) 2009-05-01 2010-11-04 Glycomimetics, Inc. Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors
US9420770B2 (en) 2009-12-01 2016-08-23 Indiana University Research & Technology Corporation Methods of modulating thrombocytopenia and modified transgenic pigs
US8921328B2 (en) 2010-09-14 2014-12-30 Glycomimetics, Inc. E-selectin antagonists
JP2014501748A (ja) * 2010-12-21 2014-01-23 リコファーマ アーベー 涙代用物
PT2794626T (pt) 2011-12-22 2018-01-12 Glycomimetics Inc Compostos de antagonistas de e-selectina
CA2891514C (en) 2012-12-07 2020-08-25 Glycomimetics, Inc. Compounds, compositions and methods using e-selectin antagonists for mobilization of hematopoietic cells
ES2754549T3 (es) 2014-12-03 2020-04-20 Glycomimetics Inc Inhibidores heterobifuncionales de E-selectinas y receptores de quimioquinas CXCR4
JP2019502727A (ja) 2016-01-22 2019-01-31 グリコミメティクス, インコーポレイテッド Pa−ilおよび/またはpa−iilレクチンの糖模倣体阻害剤
WO2017151708A1 (en) 2016-03-02 2017-09-08 Glycomimetics, Inc. Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin
EP3497131B1 (en) 2016-08-08 2022-03-09 GlycoMimetics, Inc. Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4.
US11072625B2 (en) 2016-10-07 2021-07-27 Glycomimetics, Inc. Highly potent multimeric e-selectin antagonists
CA3054605A1 (en) 2017-03-15 2018-09-20 Glycomimetics, Inc. Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists
WO2019108750A1 (en) 2017-11-30 2019-06-06 Glycomimetics, Inc. Methods of mobilizing marrow infiltrating lymphocytes and uses thereof
CN111566117A (zh) 2017-12-29 2020-08-21 糖模拟物有限公司 E-选择蛋白和半乳凝素-3的异双功能抑制剂
WO2019173229A1 (en) 2018-03-05 2019-09-12 Glycomimetics, Inc. Methods for treating acute myeloid leukemia and related conditions
WO2019241386A1 (en) * 2018-06-12 2019-12-19 Rush University Medical Center Methods for enhanced endothelialization of implanted material
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69226871T3 (de) * 1991-06-27 2009-09-24 Bristol-Myers Squibb Co. CTL4A-Rezeptor, ihn enthaltenden Fusionsproteine und deren Verwendung
DE69333346T2 (de) * 1992-10-23 2004-10-07 Inst Genetics Llc Neuartiges p- selectin ligandenprotein
JP4038236B2 (ja) * 1993-03-16 2008-01-23 オースチン・リサーチ・インスティテュート 異種移植治療におけるブタGa1α(1,3)ガラクトシルトランスフェラーゼの使用
GB9517758D0 (en) * 1995-08-31 1995-11-01 Imutran Ltd Compositions and their uses

Similar Documents

Publication Publication Date Title
JP2000509637A5 (https=)
JP2000509635A5 (https=)
JP2000509912A5 (https=)
JP2000509942A5 (https=)
JP2000507042A5 (https=)
JP2000510751A5 (https=)
JP2002502276A5 (https=)
JP2002500533A5 (https=)
JP2001511276A5 (https=)
JP2001523135A5 (https=)
JP2000509587A5 (https=)
JP2000507369A5 (https=)
JP2000507433A5 (https=)
JP2000510793A5 (https=)
JP2000508022A5 (https=)
JP2002515071A5 (https=)
JP2000511782A5 (https=)
JP2000508680A5 (https=)
JP2000509804A5 (https=)
JP2001518853A5 (https=)
JP2000509853A5 (https=)
JP2000509755A5 (https=)
JP2000510247A5 (https=)
JP2000510969A5 (https=)
JP2000508102A5 (https=)