JP2000503652A - 合成ｉｌ―１０類似体 - Google Patents
合成ｉｌ―１０類似体Info
- Publication number
- JP2000503652A JP2000503652A JP9525609A JP52560997A JP2000503652A JP 2000503652 A JP2000503652 A JP 2000503652A JP 9525609 A JP9525609 A JP 9525609A JP 52560997 A JP52560997 A JP 52560997A JP 2000503652 A JP2000503652 A JP 2000503652A
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- amino acid
- peptide
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- Ceased
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5428—IL-10
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/DK1996/000029 WO1997026278A1 (en) | 1996-01-18 | 1996-01-18 | Synthetic il-10 analogues |
| WO96/00029 | 1996-01-18 | ||
| PCT/DK1997/000021 WO1997026279A1 (en) | 1996-01-18 | 1997-01-16 | Synthetic il-10 analogues |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2000503652A true JP2000503652A (ja) | 2000-03-28 |
| JP2000503652A5 JP2000503652A5 (enExample) | 2004-11-11 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9525609A Ceased JP2000503652A (ja) | 1996-01-18 | 1997-01-16 | 合成ｉｌ―１０類似体 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6936586B1 (enExample) |
| EP (1) | EP0879245A1 (enExample) |
| JP (1) | JP2000503652A (enExample) |
| KR (1) | KR19990077344A (enExample) |
| CN (1) | CN1226899A (enExample) |
| AP (1) | AP883A (enExample) |
| AR (1) | AR006517A1 (enExample) |
| AU (2) | AU4385696A (enExample) |
| BR (1) | BR9707036A (enExample) |
| CA (1) | CA2243275A1 (enExample) |
| PL (1) | PL327928A1 (enExample) |
| RU (1) | RU2194054C2 (enExample) |
| WO (2) | WO1997026278A1 (enExample) |
| ZA (1) | ZA9784B (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997026278A1 (en) * | 1996-01-18 | 1997-07-24 | Steeno Research Group A/S | Synthetic il-10 analogues |
| WO1998010792A1 (en) * | 1996-09-11 | 1998-03-19 | Prendergast Patrick T | Immune direction therapy |
| WO1999018942A1 (en) * | 1997-10-10 | 1999-04-22 | Imperial College Innovations Ltd. | Use of csaidtm compounds for the management of uterine contractions |
| DE19851675A1 (de) * | 1998-11-10 | 2000-05-11 | Bayer Ag | Menschliche Interleukin-10 Mutantenproteine |
| JP2002532556A (ja) * | 1998-12-22 | 2002-10-02 | シェリング・コーポレーション | Ｃ型肝炎ウイルス感染のインターロイキン−１０での処置 |
| AU2001245453B2 (en) * | 2000-03-14 | 2005-08-25 | National Jewish Medical And Research Center | Method and composition for treating airway hyperresponsiveness |
| US20070160576A1 (en) * | 2001-06-05 | 2007-07-12 | Genentech, Inc. | IL-17A/F heterologous polypeptides and therapeutic uses thereof |
| US6797722B2 (en) * | 2002-05-03 | 2004-09-28 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole for the treatment of autoimmune diseases |
| RU2260598C2 (ru) * | 2003-10-29 | 2005-09-20 | Российский кардиологический научно-производственный комплекс Министерства здравоохранения РФ | Пептид, обладающий способностью ингибировать миграцию моноцитарных клеток, стимулированную белком мср-1 |
| GB0500643D0 (en) * | 2005-01-13 | 2005-02-23 | Renovo Ltd | Medicaments |
| US8889632B2 (en) | 2007-01-31 | 2014-11-18 | Dana-Farber Cancer Institute, Inc. | Stabilized p53 peptides and uses thereof |
| CA2682174C (en) | 2007-03-28 | 2021-04-06 | President And Fellows Of Harvard College | Stitched polypeptides |
| CN101980718A (zh) * | 2008-02-08 | 2011-02-23 | 爱勒让治疗公司 | 治疗性的拟肽大环化合物 |
| AU2014201269B2 (en) * | 2008-02-08 | 2016-09-15 | Aileron Therapeutics, Inc. | Therapeutic peptidomimetic macrocycles |
| RU2639523C2 (ru) | 2011-10-18 | 2017-12-21 | Эйлерон Терапьютикс, Инк. | Пептидомиметические макроциклы и их применение |
| EP2819688A4 (en) | 2012-02-15 | 2015-10-28 | Aileron Therapeutics Inc | PEPTIDOMIMETIC MACROCYCLES CROSS-LINKED WITH TRIAZOLE AND THIOETHER |
| WO2013123266A1 (en) | 2012-02-15 | 2013-08-22 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| WO2014138429A2 (en) | 2013-03-06 | 2014-09-12 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and use thereof in regulating hif1alpha |
| BR112017005598A2 (pt) | 2014-09-24 | 2017-12-12 | Aileron Therapeutics Inc | macrociclos peptidomiméticos e usos dos mesmos |
| US10253067B2 (en) | 2015-03-20 | 2019-04-09 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| CN108368161A (zh) | 2015-09-10 | 2018-08-03 | 艾瑞朗医疗公司 | 作为mcl-1调节剂的拟肽大环化合物 |
| EP4252629A3 (en) | 2016-12-07 | 2023-12-27 | Biora Therapeutics, Inc. | Gastrointestinal tract detection methods, devices and systems |
| WO2018183931A1 (en) | 2017-03-30 | 2018-10-04 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with il-10 or an il-10 agonist |
| JP7482866B2 (ja) | 2018-11-19 | 2024-05-14 | ビオラ・セラピューティクス・インコーポレイテッド | 生物学的治療薬による疾患処置方法およびデバイス |
| BR102019007044A2 (pt) * | 2019-04-05 | 2021-12-28 | Universidade Federal de Uberlândia | Peptídeos sintéticos com afinidade ao receptor de interleucina-10, composição farmacêutica e uso dos mesmos como imunomuduladores no tratamento de doenças autoimunes, inflamatórias ou alérgicas |
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| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| IL94878A (en) * | 1989-06-28 | 2003-01-12 | Schering Corp | Cytokine synthesis inhibitory factor, antagonists thereof and methods of using same |
| US5624823A (en) * | 1991-11-22 | 1997-04-29 | The General Hospital Corporation | DNA encoding procine interleukin-10 |
| CA2131524A1 (en) | 1992-03-04 | 1993-09-16 | Maria-Grazia Roncarolo | Use of interleukin-10 to suppress graft-vs.-host disease |
| RU2051922C1 (ru) * | 1992-06-19 | 1996-01-10 | Людмила Яковлевна Соловьева | СПОСОБ ВЫДЕЛЕНИЯ РЕКОМБИНАНТНОГО ИНТЕРЛЕЙКИНА - 1β ИЗ БИОМАССЫ МИКРООРГАНИЗМОВ |
| CA2085291A1 (en) | 1992-07-30 | 1994-01-31 | Martin L. Breitman | Novel receptor tyrosine kinase |
| US5328989A (en) * | 1993-03-05 | 1994-07-12 | Schering-Plough | Purification of human interleukin-10 from a cell culture medium |
| US5446128A (en) | 1993-06-18 | 1995-08-29 | The Board Of Trustees Of The University Of Illinois | Alpha-helix mimetics and methods relating thereto |
| CA2168110A1 (en) | 1993-07-26 | 1995-02-02 | Chuan-Chu Chou | Agonists and antagonists of human interleukin-10 |
| EP1013764A1 (en) * | 1994-07-05 | 2000-06-28 | Steeno Research Group A/S | Immunomodulators |
| US5654276A (en) * | 1995-06-07 | 1997-08-05 | Affymax Technologies N.V. | Peptides and compounds that bind to the IL-5 receptor |
| WO1997026278A1 (en) * | 1996-01-18 | 1997-07-24 | Steeno Research Group A/S | Synthetic il-10 analogues |
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- 1997-01-16 CA CA002243275A patent/CA2243275A1/en not_active Abandoned
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| AP9801295A0 (en) | 1998-09-30 |
| AR006517A1 (es) | 1999-09-08 |
| KR19990077344A (ko) | 1999-10-25 |
| US6936586B1 (en) | 2005-08-30 |
| AU4385696A (en) | 1997-08-11 |
| WO1997026278A1 (en) | 1997-07-24 |
| CA2243275A1 (en) | 1997-07-24 |
| BR9707036A (pt) | 1999-08-31 |
| AU718476B2 (en) | 2000-04-13 |
| PL327928A1 (en) | 1999-01-04 |
| EP0879245A1 (en) | 1998-11-25 |
| RU2194054C2 (ru) | 2002-12-10 |
| AU1301197A (en) | 1997-08-11 |
| ZA9784B (en) | 1997-07-17 |
| CN1226899A (zh) | 1999-08-25 |
| WO1997026279A1 (en) | 1997-07-24 |
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