BR9707036A - Análogos de il-10 sintéticos. - Google Patents

Análogos de il-10 sintéticos.

Info

Publication number
BR9707036A
BR9707036A BR9707036-0A BR9707036A BR9707036A BR 9707036 A BR9707036 A BR 9707036A BR 9707036 A BR9707036 A BR 9707036A BR 9707036 A BR9707036 A BR 9707036A
Authority
BR
Brazil
Prior art keywords
amino acid
peptide
acid residue
terminal amino
above formula
Prior art date
Application number
BR9707036-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Christian Gronhoj Larsen
Original Assignee
Steeno Res Group As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Steeno Res Group As filed Critical Steeno Res Group As
Publication of BR9707036A publication Critical patent/BR9707036A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5428IL-10
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BR9707036-0A 1996-01-18 1997-01-16 Análogos de il-10 sintéticos. BR9707036A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/DK1996/000029 WO1997026278A1 (en) 1996-01-18 1996-01-18 Synthetic il-10 analogues
PCT/DK1997/000021 WO1997026279A1 (en) 1996-01-18 1997-01-16 Synthetic il-10 analogues

Publications (1)

Publication Number Publication Date
BR9707036A true BR9707036A (pt) 1999-08-31

Family

ID=8155499

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9707036-0A BR9707036A (pt) 1996-01-18 1997-01-16 Análogos de il-10 sintéticos.

Country Status (14)

Country Link
US (1) US6936586B1 (enExample)
EP (1) EP0879245A1 (enExample)
JP (1) JP2000503652A (enExample)
KR (1) KR19990077344A (enExample)
CN (1) CN1226899A (enExample)
AP (1) AP883A (enExample)
AR (1) AR006517A1 (enExample)
AU (2) AU4385696A (enExample)
BR (1) BR9707036A (enExample)
CA (1) CA2243275A1 (enExample)
PL (1) PL327928A1 (enExample)
RU (1) RU2194054C2 (enExample)
WO (2) WO1997026278A1 (enExample)
ZA (1) ZA9784B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997026278A1 (en) * 1996-01-18 1997-07-24 Steeno Research Group A/S Synthetic il-10 analogues
WO1998010792A1 (en) * 1996-09-11 1998-03-19 Prendergast Patrick T Immune direction therapy
WO1999018942A1 (en) * 1997-10-10 1999-04-22 Imperial College Innovations Ltd. Use of csaidtm compounds for the management of uterine contractions
DE19851675A1 (de) * 1998-11-10 2000-05-11 Bayer Ag Menschliche Interleukin-10 Mutantenproteine
JP2002532556A (ja) * 1998-12-22 2002-10-02 シェリング・コーポレーション C型肝炎ウイルス感染のインターロイキン−10での処置
AU2001245453B2 (en) * 2000-03-14 2005-08-25 National Jewish Medical And Research Center Method and composition for treating airway hyperresponsiveness
US20070160576A1 (en) * 2001-06-05 2007-07-12 Genentech, Inc. IL-17A/F heterologous polypeptides and therapeutic uses thereof
US6797722B2 (en) * 2002-05-03 2004-09-28 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole for the treatment of autoimmune diseases
RU2260598C2 (ru) * 2003-10-29 2005-09-20 Российский кардиологический научно-производственный комплекс Министерства здравоохранения РФ Пептид, обладающий способностью ингибировать миграцию моноцитарных клеток, стимулированную белком мср-1
GB0500643D0 (en) * 2005-01-13 2005-02-23 Renovo Ltd Medicaments
US8889632B2 (en) 2007-01-31 2014-11-18 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
CA2682174C (en) 2007-03-28 2021-04-06 President And Fellows Of Harvard College Stitched polypeptides
CN101980718A (zh) * 2008-02-08 2011-02-23 爱勒让治疗公司 治疗性的拟肽大环化合物
AU2014201269B2 (en) * 2008-02-08 2016-09-15 Aileron Therapeutics, Inc. Therapeutic peptidomimetic macrocycles
RU2639523C2 (ru) 2011-10-18 2017-12-21 Эйлерон Терапьютикс, Инк. Пептидомиметические макроциклы и их применение
EP2819688A4 (en) 2012-02-15 2015-10-28 Aileron Therapeutics Inc PEPTIDOMIMETIC MACROCYCLES CROSS-LINKED WITH TRIAZOLE AND THIOETHER
WO2013123266A1 (en) 2012-02-15 2013-08-22 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
WO2014138429A2 (en) 2013-03-06 2014-09-12 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and use thereof in regulating hif1alpha
BR112017005598A2 (pt) 2014-09-24 2017-12-12 Aileron Therapeutics Inc macrociclos peptidomiméticos e usos dos mesmos
US10253067B2 (en) 2015-03-20 2019-04-09 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
CN108368161A (zh) 2015-09-10 2018-08-03 艾瑞朗医疗公司 作为mcl-1调节剂的拟肽大环化合物
EP4252629A3 (en) 2016-12-07 2023-12-27 Biora Therapeutics, Inc. Gastrointestinal tract detection methods, devices and systems
WO2018183931A1 (en) 2017-03-30 2018-10-04 Progenity Inc. Treatment of a disease of the gastrointestinal tract with il-10 or an il-10 agonist
JP7482866B2 (ja) 2018-11-19 2024-05-14 ビオラ・セラピューティクス・インコーポレイテッド 生物学的治療薬による疾患処置方法およびデバイス
BR102019007044A2 (pt) * 2019-04-05 2021-12-28 Universidade Federal de Uberlândia Peptídeos sintéticos com afinidade ao receptor de interleucina-10, composição farmacêutica e uso dos mesmos como imunomuduladores no tratamento de doenças autoimunes, inflamatórias ou alérgicas
CN121197633A (zh) 2019-12-13 2025-12-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
IL94878A (en) * 1989-06-28 2003-01-12 Schering Corp Cytokine synthesis inhibitory factor, antagonists thereof and methods of using same
US5624823A (en) * 1991-11-22 1997-04-29 The General Hospital Corporation DNA encoding procine interleukin-10
CA2131524A1 (en) 1992-03-04 1993-09-16 Maria-Grazia Roncarolo Use of interleukin-10 to suppress graft-vs.-host disease
RU2051922C1 (ru) * 1992-06-19 1996-01-10 Людмила Яковлевна Соловьева СПОСОБ ВЫДЕЛЕНИЯ РЕКОМБИНАНТНОГО ИНТЕРЛЕЙКИНА - 1β ИЗ БИОМАССЫ МИКРООРГАНИЗМОВ
CA2085291A1 (en) 1992-07-30 1994-01-31 Martin L. Breitman Novel receptor tyrosine kinase
US5328989A (en) * 1993-03-05 1994-07-12 Schering-Plough Purification of human interleukin-10 from a cell culture medium
US5446128A (en) 1993-06-18 1995-08-29 The Board Of Trustees Of The University Of Illinois Alpha-helix mimetics and methods relating thereto
CA2168110A1 (en) 1993-07-26 1995-02-02 Chuan-Chu Chou Agonists and antagonists of human interleukin-10
EP1013764A1 (en) * 1994-07-05 2000-06-28 Steeno Research Group A/S Immunomodulators
US5654276A (en) * 1995-06-07 1997-08-05 Affymax Technologies N.V. Peptides and compounds that bind to the IL-5 receptor
WO1997026278A1 (en) * 1996-01-18 1997-07-24 Steeno Research Group A/S Synthetic il-10 analogues

Also Published As

Publication number Publication date
AP883A (en) 2000-10-25
AP9801295A0 (en) 1998-09-30
AR006517A1 (es) 1999-09-08
KR19990077344A (ko) 1999-10-25
US6936586B1 (en) 2005-08-30
AU4385696A (en) 1997-08-11
WO1997026278A1 (en) 1997-07-24
CA2243275A1 (en) 1997-07-24
AU718476B2 (en) 2000-04-13
PL327928A1 (en) 1999-01-04
EP0879245A1 (en) 1998-11-25
JP2000503652A (ja) 2000-03-28
RU2194054C2 (ru) 2002-12-10
AU1301197A (en) 1997-08-11
ZA9784B (en) 1997-07-17
CN1226899A (zh) 1999-08-25
WO1997026279A1 (en) 1997-07-24

Similar Documents

Publication Publication Date Title
BR9707036A (pt) Análogos de il-10 sintéticos.
Cox Endogenous opioid peptides: a guide to structures and terminology
EP0793675A4 (en) METHOD AND COMPOSITIONS FOR INHIBITING PHENOMENAL RELATIONSHIPS WITH MEMBRANE FUSIONS, INCLUDING THE TRANSMISSION OF HIV
NO20050998L (no) DNA som koder for et biologisk aktivt fragment av baktericid/premeabilitetsokende protein fremgangsmate for fremstilling av dette, samt farmasoytisk preparat inneholdende dette
Malpezzi et al. Characterization of peptides in sea anemone venom collected by a novel procedure
CA2050300A1 (en) Tnf-inhibiting proteins and the preparation thereof
EP0333356A3 (en) Hirudin peptides
YU71395A (sh) Acilovani analozi insulina
EP1440980A3 (en) Peptide analogs of human myelin basic protein
ATE108662T1 (de) Antimikrobielle peptide, zusammensetzungen, die diese enthalten, und verwendungen daraus.
AU6020099A (en) Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
RU2000109305A (ru) ЗАЖИВЛЕНИЕ ПЕРЕЛОМОВ С ПОМОЩЬЮ АНАЛОГОВ ПЕПТИДА, ПОДОБНОГО ПАРАТИРЕОИДНОМУ ГОРМОНУ (РТНrР)
DE69033038D1 (de) Zyklische Peptide mit aggregationshemmenden Eigenschaften
WO1994029450A3 (en) Novel, recombinantly produced spider silk analogs
AU9315398A (en) Chemokine peptides, variants, derivatives and analogs. their use in methods to inhibit or augment an inflammatory response
KR960703015A (ko) 후천성 면역결핍증 치료용 약물의 제조시 노나- 및 데카펩타이드의 용도(Use of nona-and decapeptides in the preparation of a durg for the treatment of AIDS)
KR880009045A (ko) 혈액 응고 방지성 펩티드
AU1633200A (en) Human parathyroid hormone modifications, preparation and use
WO1999006440A8 (en) Novel synthetic peptides with antimicrobial and endotoxin neutralizing properties for management of the sepsis syndrome
WO2001051673A8 (en) Methods and compositions for inhibition of membrane fusion-associated events, including hiv transmission
RU98115293A (ru) Синтетические аналоги il-10
BR0012418A (pt) Derivados de peptìdeo cìclicos como inibidores de integrina alfavbeta6
HUP0105094A2 (hu) IGF-I- és IGF-II-gátló növekedési hormont leadó hormon antagonista analógjai és alkalmazásuk
AU641215B2 (en) Stabilized sulfonate, sulfate, phosphonate and phosphate derivatives of hirudin
CA2196308A1 (en) Peptide, bronchodilator and blood flow ameliorant

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]