BR9707036A - Análogos de il-10 sintéticos. - Google Patents

Análogos de il-10 sintéticos.

Info

Publication number
BR9707036A
BR9707036A BR9707036-0A BR9707036A BR9707036A BR 9707036 A BR9707036 A BR 9707036A BR 9707036 A BR9707036 A BR 9707036A BR 9707036 A BR9707036 A BR 9707036A
Authority
BR
Brazil
Prior art keywords
amino acid
peptide
acid residue
terminal amino
above formula
Prior art date
Application number
BR9707036-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Christian Gronhoj Larsen
Original Assignee
Steeno Res Group As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Steeno Res Group As filed Critical Steeno Res Group As
Publication of BR9707036A publication Critical patent/BR9707036A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5428IL-10
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BR9707036-0A 1996-01-18 1997-01-16 Análogos de il-10 sintéticos. BR9707036A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/DK1996/000029 WO1997026278A1 (en) 1996-01-18 1996-01-18 Synthetic il-10 analogues
PCT/DK1997/000021 WO1997026279A1 (en) 1996-01-18 1997-01-16 Synthetic il-10 analogues

Publications (1)

Publication Number Publication Date
BR9707036A true BR9707036A (pt) 1999-08-31

Family

ID=8155499

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9707036-0A BR9707036A (pt) 1996-01-18 1997-01-16 Análogos de il-10 sintéticos.

Country Status (14)

Country Link
US (1) US6936586B1 (enExample)
EP (1) EP0879245A1 (enExample)
JP (1) JP2000503652A (enExample)
KR (1) KR19990077344A (enExample)
CN (1) CN1226899A (enExample)
AP (1) AP883A (enExample)
AR (1) AR006517A1 (enExample)
AU (2) AU4385696A (enExample)
BR (1) BR9707036A (enExample)
CA (1) CA2243275A1 (enExample)
PL (1) PL327928A1 (enExample)
RU (1) RU2194054C2 (enExample)
WO (2) WO1997026278A1 (enExample)
ZA (1) ZA9784B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997026278A1 (en) * 1996-01-18 1997-07-24 Steeno Research Group A/S Synthetic il-10 analogues
WO1998010792A1 (en) * 1996-09-11 1998-03-19 Prendergast Patrick T Immune direction therapy
AU9449398A (en) * 1997-10-10 1999-05-03 Imperial College Innovations Ltd. Use of csaidtm compounds for the management of uterine contractions
DE19851675A1 (de) * 1998-11-10 2000-05-11 Bayer Ag Menschliche Interleukin-10 Mutantenproteine
US6685931B1 (en) 1998-12-22 2004-02-03 Schering Corporation Treatment of hepatitis C virus infections with interleukin-10
EP1265634A4 (en) * 2000-03-14 2005-12-28 Nat Jewish Med & Res Center METHOD AND COMPOSITION FOR TREATING RESPIRATORY HYPERSENSIBILITY
US20070160576A1 (en) * 2001-06-05 2007-07-12 Genentech, Inc. IL-17A/F heterologous polypeptides and therapeutic uses thereof
US6797722B2 (en) * 2002-05-03 2004-09-28 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole for the treatment of autoimmune diseases
RU2260598C2 (ru) * 2003-10-29 2005-09-20 Российский кардиологический научно-производственный комплекс Министерства здравоохранения РФ Пептид, обладающий способностью ингибировать миграцию моноцитарных клеток, стимулированную белком мср-1
GB0500643D0 (en) * 2005-01-13 2005-02-23 Renovo Ltd Medicaments
PL2118123T3 (pl) 2007-01-31 2016-06-30 Dana Farber Cancer Inst Inc Stabilizowane peptydy p53 i ich zastosowania
JP5631201B2 (ja) 2007-03-28 2014-11-26 プレジデント アンド フェローズ オブ ハーバード カレッジ ステッチングされたポリペプチド
AU2014201269B2 (en) * 2008-02-08 2016-09-15 Aileron Therapeutics, Inc. Therapeutic peptidomimetic macrocycles
CN104474529A (zh) 2008-02-08 2015-04-01 爱勒让治疗公司 治疗性的拟肽大环化合物
EP2768518A4 (en) 2011-10-18 2015-05-27 Aileron Therapeutics Inc PEPTIDOMIMETIC MACROCYCLES
CA2864120A1 (en) 2012-02-15 2013-08-22 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
RU2642299C2 (ru) 2012-02-15 2018-01-24 Эйлерон Терапьютикс, Инк. P53 пептидомиметические макроциклы
WO2014138429A2 (en) 2013-03-06 2014-09-12 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and use thereof in regulating hif1alpha
EP3197478A4 (en) 2014-09-24 2018-05-30 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
JP2018516844A (ja) 2015-03-20 2018-06-28 エルロン・セラピューティクス・インコーポレイテッドAileron Therapeutics,Inc. ペプチド模倣大環状分子およびその使用
EP3347372A4 (en) 2015-09-10 2019-09-04 Aileron Therapeutics, Inc. PEPTIDOMIMETIC MACROCYCLES AS MODULATORS OF MCL-1
EP3551034A1 (en) 2016-12-07 2019-10-16 Progenity, Inc. Gastrointestinal tract detection methods, devices and systems
CA3054156A1 (en) 2017-03-30 2018-10-04 Progenity Inc. Treatment of a disease of the gastrointestinal tract with il-10 or an il-10 agonist
WO2020106757A1 (en) 2018-11-19 2020-05-28 Progenity, Inc. Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
BR102019007044A2 (pt) * 2019-04-05 2021-12-28 Universidade Federal de Uberlândia Peptídeos sintéticos com afinidade ao receptor de interleucina-10, composição farmacêutica e uso dos mesmos como imunomuduladores no tratamento de doenças autoimunes, inflamatórias ou alérgicas
CN121197633A (zh) 2019-12-13 2025-12-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
IL94878A (en) * 1989-06-28 2003-01-12 Schering Corp Cytokine synthesis inhibitory factor, antagonists thereof and methods of using same
US5624823A (en) * 1991-11-22 1997-04-29 The General Hospital Corporation DNA encoding procine interleukin-10
CA2131524A1 (en) 1992-03-04 1993-09-16 Maria-Grazia Roncarolo Use of interleukin-10 to suppress graft-vs.-host disease
RU2051922C1 (ru) * 1992-06-19 1996-01-10 Людмила Яковлевна Соловьева СПОСОБ ВЫДЕЛЕНИЯ РЕКОМБИНАНТНОГО ИНТЕРЛЕЙКИНА - 1β ИЗ БИОМАССЫ МИКРООРГАНИЗМОВ
CA2085291A1 (en) 1992-07-30 1994-01-31 Martin L. Breitman Novel receptor tyrosine kinase
US5328989A (en) * 1993-03-05 1994-07-12 Schering-Plough Purification of human interleukin-10 from a cell culture medium
US5446128A (en) 1993-06-18 1995-08-29 The Board Of Trustees Of The University Of Illinois Alpha-helix mimetics and methods relating thereto
IL110413A0 (en) 1993-07-26 1994-10-21 Schering Corp Agonists and antagonists of human interleukin-10
US6159937A (en) * 1994-07-05 2000-12-12 Steeno Research Group A/S Immunomodulators
US5654276A (en) * 1995-06-07 1997-08-05 Affymax Technologies N.V. Peptides and compounds that bind to the IL-5 receptor
WO1997026278A1 (en) * 1996-01-18 1997-07-24 Steeno Research Group A/S Synthetic il-10 analogues

Also Published As

Publication number Publication date
EP0879245A1 (en) 1998-11-25
ZA9784B (en) 1997-07-17
CA2243275A1 (en) 1997-07-24
JP2000503652A (ja) 2000-03-28
KR19990077344A (ko) 1999-10-25
AU718476B2 (en) 2000-04-13
PL327928A1 (en) 1999-01-04
AU4385696A (en) 1997-08-11
AP883A (en) 2000-10-25
WO1997026278A1 (en) 1997-07-24
RU2194054C2 (ru) 2002-12-10
WO1997026279A1 (en) 1997-07-24
AP9801295A0 (en) 1998-09-30
AU1301197A (en) 1997-08-11
AR006517A1 (es) 1999-09-08
US6936586B1 (en) 2005-08-30
CN1226899A (zh) 1999-08-25

Similar Documents

Publication Publication Date Title
AR006517A1 (es) Polipeptido que alcanza un total de alrededor de 30 aminoacidos; sustancia, peptidomimetico y composicion farmaceutica resultantes; usos del polipeptidoy proceso para la sintesis del polipeptido.
Cox Endogenous opioid peptides: a guide to structures and terminology
EP0793675A4 (en) METHOD AND COMPOSITIONS FOR INHIBITING PHENOMENAL RELATIONSHIPS WITH MEMBRANE FUSIONS, INCLUDING THE TRANSMISSION OF HIV
NO20050998L (no) DNA som koder for et biologisk aktivt fragment av baktericid/premeabilitetsokende protein fremgangsmate for fremstilling av dette, samt farmasoytisk preparat inneholdende dette
Malpezzi et al. Characterization of peptides in sea anemone venom collected by a novel procedure
CA2050300A1 (en) Tnf-inhibiting proteins and the preparation thereof
EP0333356A3 (en) Hirudin peptides
KR900017607A (ko) 프로테이나아제 억제제, 이것의 제조방법 및 이들을 함유한 의약품
EP1548028A4 (en) SUBSTITUTED WT1 PEPTIDES
EP1440980A3 (en) Peptide analogs of human myelin basic protein
ATE108662T1 (de) Antimikrobielle peptide, zusammensetzungen, die diese enthalten, und verwendungen daraus.
ES2130118T3 (es) Peptidos ciclicos con actividad antiagregante.
AU6020099A (en) Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
RU2000109305A (ru) ЗАЖИВЛЕНИЕ ПЕРЕЛОМОВ С ПОМОЩЬЮ АНАЛОГОВ ПЕПТИДА, ПОДОБНОГО ПАРАТИРЕОИДНОМУ ГОРМОНУ (РТНrР)
AU9315398A (en) Chemokine peptides, variants, derivatives and analogs. their use in methods to inhibit or augment an inflammatory response
KR960703015A (ko) 후천성 면역결핍증 치료용 약물의 제조시 노나- 및 데카펩타이드의 용도(Use of nona-and decapeptides in the preparation of a durg for the treatment of AIDS)
KR880009045A (ko) 혈액 응고 방지성 펩티드
ATE458054T1 (de) Menschliches parathyroidhormon, modifikationen, herstellung und verwendung
WO1999006440A8 (en) Novel synthetic peptides with antimicrobial and endotoxin neutralizing properties for management of the sepsis syndrome
WO2001051673A8 (en) Methods and compositions for inhibition of membrane fusion-associated events, including hiv transmission
RU98115293A (ru) Синтетические аналоги il-10
BR0012418A (pt) Derivados de peptìdeo cìclicos como inibidores de integrina alfavbeta6
NZ503235A (en) Amino-terminally truncated RANTES as chemokine antagonists
HUP0105094A2 (hu) IGF-I- és IGF-II-gátló növekedési hormont leadó hormon antagonista analógjai és alkalmazásuk
AU641215B2 (en) Stabilized sulfonate, sulfate, phosphonate and phosphate derivatives of hirudin

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]