ITPD20050207A1 - Nuove composizioni farmaceutiche contenenti acido ialuronico e collagenas nel trattamento topico di ferite, ustioni ed ulcere - Google Patents

Nuove composizioni farmaceutiche contenenti acido ialuronico e collagenas nel trattamento topico di ferite, ustioni ed ulcere

Info

Publication number
ITPD20050207A1
ITPD20050207A1 IT000207A ITPD20050207A ITPD20050207A1 IT PD20050207 A1 ITPD20050207 A1 IT PD20050207A1 IT 000207 A IT000207 A IT 000207A IT PD20050207 A ITPD20050207 A IT PD20050207A IT PD20050207 A1 ITPD20050207 A1 IT PD20050207A1
Authority
IT
Italy
Prior art keywords
ulcers
wounds
burns
hyaluronic acid
compositions containing
Prior art date
Application number
IT000207A
Other languages
English (en)
Inventor
Lanfranco Callegaro
Salvatore Caruso
Giovanni Gennari
Antonio Giannelli
Susanna Vaccari
Original Assignee
Fidia Farmaceutici
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Farmaceutici filed Critical Fidia Farmaceutici
Priority to IT000207A priority Critical patent/ITPD20050207A1/it
Priority to PT06754678T priority patent/PT1901755E/pt
Priority to JP2008519863A priority patent/JP5322637B2/ja
Priority to EP06754678A priority patent/EP1901755B1/en
Priority to PCT/EP2006/006616 priority patent/WO2007006484A1/en
Priority to DK06754678.8T priority patent/DK1901755T3/da
Priority to ES06754678T priority patent/ES2352350T3/es
Priority to BRPI0612736-3A priority patent/BRPI0612736A2/pt
Priority to CA2613976A priority patent/CA2613976C/en
Priority to US11/921,835 priority patent/US8900576B2/en
Priority to AT06754678T priority patent/ATE480244T1/de
Priority to AU2006268950A priority patent/AU2006268950B2/en
Priority to DE602006016799T priority patent/DE602006016799D1/de
Priority to PL06754678T priority patent/PL1901755T3/pl
Priority to HK08108480.2A priority patent/HK1116683B/en
Priority to SI200630841T priority patent/SI1901755T1/sl
Publication of ITPD20050207A1 publication Critical patent/ITPD20050207A1/it
Priority to US14/481,615 priority patent/US9603910B2/en
Priority to US15/423,208 priority patent/US11040089B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886Metalloendopeptidases (3.4.24), e.g. collagenase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24Metalloendopeptidases (3.4.24)
    • C12Y304/24003Microbial collagenase (3.4.24.3)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IT000207A 2005-07-07 2005-07-07 Nuove composizioni farmaceutiche contenenti acido ialuronico e collagenas nel trattamento topico di ferite, ustioni ed ulcere ITPD20050207A1 (it)

Priority Applications (18)

Application Number Priority Date Filing Date Title
IT000207A ITPD20050207A1 (it) 2005-07-07 2005-07-07 Nuove composizioni farmaceutiche contenenti acido ialuronico e collagenas nel trattamento topico di ferite, ustioni ed ulcere
US11/921,835 US8900576B2 (en) 2005-07-07 2006-07-05 Pharmaceutical compositions containing hyaluronic acid and collagenase for the topical treatment of wounds, burns and ulcers
AT06754678T ATE480244T1 (de) 2005-07-07 2006-07-05 Neue, hyaluronsäure oder hyaluronsaure derivate und collagenase enthaltende pharmazeutische zusammensetzungen zur topischen behandlung von wunden, verbrennungen und geschwüren
EP06754678A EP1901755B1 (en) 2005-07-07 2006-07-05 New pharmaceutical compositions containing hyaluronic acid or its derivatives and collagenase for the topical treatment of wounds, burns and ulcers
PCT/EP2006/006616 WO2007006484A1 (en) 2005-07-07 2006-07-05 New pharmaceutical compositions containing hyaluronic acid and collagenase for the topical treatment of wounds, burns and ulcers
DK06754678.8T DK1901755T3 (da) 2005-07-07 2006-07-05 Nye farmaceutiske sammensætninger indeholdende hyaluronsyre eller dens derivater og collagenase til topisk behandling af sår, forbrændinger og ulcera
ES06754678T ES2352350T3 (es) 2005-07-07 2006-07-05 Nuevas composiciones farmacéuticas que contienen ácido hialurónico o sus derivados y colagenasa para el tratamiento de heridas, quemaduras y úlceras.
BRPI0612736-3A BRPI0612736A2 (pt) 2005-07-07 2006-07-05 medicamento, composições farmacêuticas lipofìlicas, usos de medicamentos e de composições farmacêuticas lipofìlicas, e, processo para a preparação de um lipogel
CA2613976A CA2613976C (en) 2005-07-07 2006-07-05 New pharmaceutical compositions containing hyaluronic acid and collagenase for the topical treatment of wounds, burns and ulcers
PT06754678T PT1901755E (pt) 2005-07-07 2006-07-05 Novas composições farmacêuticas contendo ácido hialurónico e colagenase para o tratamento tópico de feridas, queimaduras e úlceras
JP2008519863A JP5322637B2 (ja) 2005-07-07 2006-07-05 創傷、火傷及び潰瘍の局所的治療のためのヒアルロン酸及びコラーゲナーゼを含有する新規医薬組成物
AU2006268950A AU2006268950B2 (en) 2005-07-07 2006-07-05 New pharmaceutical compositions containing hyaluronic acid and collagenase for the topical treatment of wounds, burns and ulcers
DE602006016799T DE602006016799D1 (de) 2005-07-07 2006-07-05 NEUE, HYALURONSÄURE ODER HYALURONSàURE DERIVATE UND COLLAGENASE ENTHALTENDE PHARMAZEUTISCHE ZUSAMMENSETZUNGEN ZUR TOPISCHEN BEHANDLUNG VON WUNDEN, VERBRENNUNGEN UND GESCHWÜREN
PL06754678T PL1901755T3 (pl) 2005-07-07 2006-07-05 Nowe kompozycje farmaceutyczne zawierające kwas hialuronowy lub jego pochodne i kolagenazę do miejscowego leczenia ran, oparzeń i owrzodzeń
HK08108480.2A HK1116683B (en) 2005-07-07 2006-07-05 New pharmaceutical compositions containing hyaluronic acid or its derivatives and collagenase for the topical treatment of wounds, burns and ulcers
SI200630841T SI1901755T1 (sl) 2005-07-07 2006-07-05 Novi farmacevtski sestavki, ki vsebujejo hialuronsko kislino ali njene derivate in kolagenazo, za topično zdravljenje ran, opeklin in ulkusov
US14/481,615 US9603910B2 (en) 2005-07-07 2014-09-09 Pharmaceutical compositions containing hyaluronic acid and collagenase for the topical treatment of wounds, burns and ulcers
US15/423,208 US11040089B2 (en) 2005-07-07 2017-02-02 Pharmaceutical compositions containing hyaluronic acid and collagenase for the topical treatment of wounds, burns and ulcers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000207A ITPD20050207A1 (it) 2005-07-07 2005-07-07 Nuove composizioni farmaceutiche contenenti acido ialuronico e collagenas nel trattamento topico di ferite, ustioni ed ulcere

Publications (1)

Publication Number Publication Date
ITPD20050207A1 true ITPD20050207A1 (it) 2007-01-08

Family

ID=37023161

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000207A ITPD20050207A1 (it) 2005-07-07 2005-07-07 Nuove composizioni farmaceutiche contenenti acido ialuronico e collagenas nel trattamento topico di ferite, ustioni ed ulcere

Country Status (15)

Country Link
US (3) US8900576B2 (it)
EP (1) EP1901755B1 (it)
JP (1) JP5322637B2 (it)
AT (1) ATE480244T1 (it)
AU (1) AU2006268950B2 (it)
BR (1) BRPI0612736A2 (it)
CA (1) CA2613976C (it)
DE (1) DE602006016799D1 (it)
DK (1) DK1901755T3 (it)
ES (1) ES2352350T3 (it)
IT (1) ITPD20050207A1 (it)
PL (1) PL1901755T3 (it)
PT (1) PT1901755E (it)
SI (1) SI1901755T1 (it)
WO (1) WO2007006484A1 (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102711808B (zh) 2009-12-08 2015-08-19 史密夫和内修整形外科股份公司 具有增强的酶活性的酶学伤口清创组合物
EP2570124B1 (en) * 2010-05-14 2016-11-02 Sanidad Y Residencias 21, S.A. Oleuropein compositions for healing wounds and ulcers in elderly people and/or diabetics
KR101831918B1 (ko) 2010-06-11 2018-02-27 한국원자력의학원 히알루론산의 탈아세틸화 가수분해효소, 및 이에 의해 탈아세틸화된 히알루론산 및 이의 유도체
ES2385239B1 (es) * 2010-09-30 2013-06-19 Proteos Biotech S.L.U. Uso de colagenasa g recombinante, colagenasa h recombinante y pz-peptidasa recombinante para el tratamiento de enfermedades que cursan con alteraciones del colágeno.
DK2734216T3 (en) 2011-07-20 2018-11-19 Mediwound Ltd PROTEOLYTIC EXTRACT FROM BROMELAIN FOR TREATMENT OF CONNECTIVE TISSUE DISEASES
NZ627372A (en) 2012-01-12 2016-04-29 Auxilium Int Holdings Inc Clostridium histolyticum enzymes and methods for the use thereof
CN102552479B (zh) * 2012-01-19 2013-12-04 孙万奎 一种用于治疗糖尿病足的中药组合物
ES2424294B1 (es) * 2012-03-22 2014-07-21 Lipotec, S.A. Exopolisacárido para el tratamiento y/o cuidado de la piel, mucosas, cabello y/o uñas
ITPD20120118A1 (it) 2012-04-18 2013-10-19 Fidia Farmaceutici "nuovo processo di produzione e purificazione dell'enzima collagenasi da vibrio alginolyticus"
ITPD20120173A1 (it) * 2012-05-31 2013-12-01 Fidia Farmaceutici "nuovo sistema di rilascio di proteine idrofobiche"
ITPD20120360A1 (it) * 2012-11-30 2014-05-31 Fidia Farmaceutici "nuovi geli viscoelastici in chirurgia oftalmica"
US20140328826A1 (en) * 2013-05-01 2014-11-06 COLE Research & Design, Inc. Product and method for treating keloid scars, hypertrophic scars and burn scars with contracture
US10117892B2 (en) * 2013-08-29 2018-11-06 Allergan, Inc. Devices and methods for reducing the appearance of cellulite
EP3324925B1 (en) * 2015-07-23 2022-12-14 Mary Kay, Inc. Topical skin formulations
KR20250021648A (ko) 2017-03-01 2025-02-13 엔도 오퍼레이션즈 리미티드 셀룰라이트를 평가하고 치료하기 위한 장치 및 방법
CN110741085B (zh) 2017-03-28 2025-03-04 恩多风投有限公司 生产胶原酶的改进方法
WO2019046678A1 (en) * 2017-09-01 2019-03-07 Excel Med, Llc PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF CHOLOIDS AND USES THEREOF
CN113759122A (zh) * 2020-06-05 2021-12-07 张曼 尿液蛋白质z及其多肽片段在烧伤中的应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4174389A (en) * 1977-05-13 1979-11-13 Cope Louise A Ophthalmic use of collagenase
IT1212892B (it) * 1983-10-11 1989-11-30 Della Valle Francesco Acido ialuronico ottenuto per mezzodi filtrazione molecolare sprovvisto di attivita' infiammatoria e sua utilizzazione terapeutica
CA1227132A (fr) * 1983-01-05 1987-09-22 Robert J. Weill Preparation a activite collagenolytique ayant une activite elevee et compositions pharmaceutiques la contenant
DE3504905A1 (de) 1985-02-13 1986-08-14 J. Kühn GmbH & Co Präzisionswerkzeug KG, 4270 Dorsten Werkzeughalter o.dgl.
US4851521A (en) * 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
JP3449738B2 (ja) * 1991-07-10 2003-09-22 武田薬品工業株式会社 水溶性組成物
US5393792A (en) * 1991-11-20 1995-02-28 Advance Biofactures Of Curacao, N.V. High dosage topical forms of collagenase
IL100112A (en) * 1991-11-21 1996-01-31 Yeda Res & Dev Microdelivery device for enhanced drug administration to the eye
DE4200080A1 (de) * 1992-01-03 1993-09-30 Reinmueller Johannes Pharmazeutische Zusammensetzung zur Wund-, Narben- und Keloidbehandlung
WO1994024273A1 (en) 1993-04-16 1994-10-27 Baxter International Inc. Stable collagenase compositions and methods for their preparation
EP0637450A3 (en) * 1993-08-04 1995-04-05 Collagen Corp Method and composition for resuscitation of hereditary tissue.
US5589171A (en) * 1994-08-22 1996-12-31 Advance Biofactures Of Curacao Treatment of Dupuytren's disease with collagenase
US5718897A (en) 1995-06-07 1998-02-17 Trustees Of Tufts College Enhancing keratinocyte migration and proliferation
DE19641672A1 (de) * 1996-10-10 1998-04-16 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen auf der Basis von ethylenoxidfreien und propylenoxidfreien Emulgatoren zur Herstellung von Mikroemulsionsgelen
US6120751A (en) * 1997-03-21 2000-09-19 Imarx Pharmaceutical Corp. Charged lipids and uses for the same
US6086872A (en) * 1997-03-27 2000-07-11 Advance Biofactures Of Curacao, Nv Amelioration of dupuytren's disease
IT1302534B1 (it) * 1998-12-21 2000-09-05 Fidia Advanced Biopolymers Srl Composizioni iniettabili, biocompatibili e biodegradabili comprendentialmeno un derivato dell'acido ialuronico, cellule condrogeniche, per
IT1306679B1 (it) * 1999-06-29 2001-10-02 Fidia Advanced Biopolymers Srl Uso dei derivati dell'acido ialuronico per la preparazione dicomposizoni farmaceutiche e biomateriali per la prevenzione della
JP2002020279A (ja) * 2000-06-30 2002-01-23 Taisho Pharmaceut Co Ltd 点眼液
DE10246340A1 (de) * 2002-10-04 2004-04-29 Wohlrab, David, Dr. Kombinationspräparat aus Hyaluronsäure und mindestens einem Lokalanästhetikum und dessen Verwendung
EP1433845A1 (en) * 2002-12-23 2004-06-30 Georg-August-Universität Clostridium tetani collagenase and uses thereof

Also Published As

Publication number Publication date
JP5322637B2 (ja) 2013-10-23
EP1901755B1 (en) 2010-09-08
SI1901755T1 (sl) 2011-01-31
US20140377249A1 (en) 2014-12-25
US9603910B2 (en) 2017-03-28
HK1116683A1 (en) 2009-01-02
EP1901755A1 (en) 2008-03-26
PL1901755T3 (pl) 2011-03-31
US20080206228A1 (en) 2008-08-28
ATE480244T1 (de) 2010-09-15
US20170209552A1 (en) 2017-07-27
CA2613976A1 (en) 2007-01-18
US11040089B2 (en) 2021-06-22
CA2613976C (en) 2013-11-19
JP2009500367A (ja) 2009-01-08
AU2006268950B2 (en) 2011-01-06
WO2007006484A1 (en) 2007-01-18
DK1901755T3 (da) 2011-01-10
US8900576B2 (en) 2014-12-02
DE602006016799D1 (de) 2010-10-21
BRPI0612736A2 (pt) 2012-10-02
ES2352350T3 (es) 2011-02-17
AU2006268950A1 (en) 2007-01-18
PT1901755E (pt) 2010-12-16

Similar Documents

Publication Publication Date Title
PL1901755T3 (pl) Nowe kompozycje farmaceutyczne zawierające kwas hialuronowy lub jego pochodne i kolagenazę do miejscowego leczenia ran, oparzeń i owrzodzeń
CA2931174C (en) No-emitting medical dressing comprising an no-generating module and a radiation-emitting module
UY27486A1 (es) Queratinocitos utilizables como sustancia biológicamente activa en el tratamiento de heridas
IL154888A (en) Aqueous Pharmaceutical Gel Preparation Containing At least One Vitamin D or One Vitamin D Analog At least One Corticosteroid
IL222773B (en) Biaryl compounds, pharmaceutical compositions comprising the same, use of such compounds in the manufacture of medicaments and in vitro methods and devices using such compounds
DE602006014990D1 (de) Intranasale verabreichung von schnell wirkendem insulin
BRPI0507198A (pt) derivados de bisariluréia
CY1108992T1 (el) Η χρηση του υαλουρονικου οξεος για την παρασκευη συνθεσεων για τη θεραπευτικη αντιμετωπιση υποτροπιαζουσων αφθων της στοματικης κοιλοτητας
CY1109351T1 (el) Φαρμακευτικες συνθεσεις που περιεχουν διαμινοοξειδαση
DE502007003850D1 (de) Gel zur Behandlung von Wunden
AR049518A1 (es) Composicion farmaceutica que comprende un agente siliconado y dos principios activos solubilizados
WO2006037606A3 (en) Wound dressing compositions, especially for delivery of protease inhibitors
AU2002214389A1 (en) Pharmaceutical composition containing honey for the treatment of wounds
BRPI0408299A (pt) inibidores de catepsina s
PA8525801A1 (es) Compuestos de pirazol, composiciones farmacéuticas, y métodos para modular y/o inhibir la actividad de erab/hadh2
ATE252383T1 (de) Verwendung von 2-methyl-thiazolidin-2,4- dicarbonsäure und / oder ihrer physiologisch verträglichen salze zur herstellung eines medikaments zur behandlung von krebserkrankungen
ECSP056186A (es) Composición farmacéutica en forma de hidrogel para administración transdérmica de sustancias activas
FR2887150B1 (fr) Composition pharmaceutique comprenant un elastomere organopolysiloxane et un principe actif solubilise
DE60135454D1 (de) Pharmazeutische gel-zusammensetzung
ATE502643T1 (de) Natürliche zusammensetzung
SE0301885D0 (sv) New use IV
AU2006272424A8 (en) Homogemcitabines
ITMI20052515A1 (it) Formulazione farmaceutica per il trattamento della osteoartrite
AR015362A1 (es) Uso de una composicion topicamente activa para la manufactura de un medicamento util para el tratamiento de acne vulgaris y/o para producir efectos anti-envejecimiento
WO2006075932A3 (en) Remedy to accelerate healing of wound and burn