ITMI971628A0 - - Google Patents
Info
- Publication number
- ITMI971628A0 ITMI971628A0 ITMI971628A ITMI971628A ITMI971628A0 IT MI971628 A0 ITMI971628 A0 IT MI971628A0 IT MI971628 A ITMI971628 A IT MI971628A IT MI971628 A ITMI971628 A IT MI971628A IT MI971628 A0 ITMI971628 A0 IT MI971628A0
- Authority
- IT
- Italy
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- C07F9/5728—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/5765—Six-membered rings condensed with carbocyclic rings or carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/446,617 US6410782B1 (en) | 1997-07-09 | 1997-07-08 | Diphosphonic acid salts for the treatment of osteoporosis |
| IT97MI001628A IT1293305B1 (it) | 1997-07-09 | 1997-07-09 | Sali di acidi difosfonici e loro impiego farmacologico nel trattamento dell'osteoporosi |
| AU88067/98A AU8806798A (en) | 1997-07-09 | 1998-07-08 | Diphosphonic acid salts for the treatment of osteoporosis |
| PT98939625T PT994884E (pt) | 1997-07-09 | 1998-07-08 | Sais de acido difosfonico para o tratamento da osteoporose |
| IL13317298A IL133172A (en) | 1997-07-09 | 1998-07-08 | Diphosphonic acid salts for the treatment of osteoporosis |
| CNB988069326A CN1161363C (zh) | 1997-07-09 | 1998-07-08 | 用于治疗骨质疏松症的双膦酸盐 |
| AT98939625T ATE251631T1 (de) | 1997-07-09 | 1998-07-08 | Dipohosphonsäuresalze für die behandlung von osteoporose |
| HU0004679A HUP0004679A3 (en) | 1997-07-09 | 1998-07-08 | Diphosphonic acid-aminoalcohol salts and medicines containing the same |
| ES98939625T ES2207853T3 (es) | 1997-07-09 | 1998-07-08 | Sales de acido difosfonico para el tratamiento de la osteoporosis. |
| DK98939625T DK0994884T3 (da) | 1997-07-09 | 1998-07-08 | Diphosphonsyresalte til behandling af osteoporose |
| EP98939625A EP0994884B1 (en) | 1997-07-09 | 1998-07-08 | Diphosphonic acid salts for the treatment of osteoporosis |
| PCT/EP1998/004238 WO1999002539A1 (en) | 1997-07-09 | 1998-07-08 | Diphosphonic acid salts for the treatment of osteoporosis |
| KR10-2000-7000135A KR100396036B1 (ko) | 1997-07-09 | 1998-07-08 | 골다공증 치료를 위한 디포스폰산 염 |
| DE69818823T DE69818823T2 (de) | 1997-07-09 | 1998-07-08 | Dipohosphonsäuresalze für die behandlung von osteoporose |
| JP2000502060A JP3681637B2 (ja) | 1997-07-09 | 1998-07-08 | 骨粗鬆症の治療用のジホスホン酸塩 |
| CA002303210A CA2303210A1 (en) | 1997-07-09 | 1998-07-08 | Salts of diphosphonic acids and amino-alcohols for the treatment of osteoporosis |
| BR9810561-2A BR9810561A (pt) | 1997-07-09 | 1998-07-08 | Difosfonatos ou sais de ácidos difosfÈnicos e derivados de amino-álcoois aromáticos, processo para preparação de difosfonatos, uso de difosfonatos ou seus sais, e, composições farmacêuticas para o tratamento de osteoporose |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT97MI001628A IT1293305B1 (it) | 1997-07-09 | 1997-07-09 | Sali di acidi difosfonici e loro impiego farmacologico nel trattamento dell'osteoporosi |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI971628A0 true ITMI971628A0 (US06559137-20030506-C00166.png) | 1997-07-09 |
| ITMI971628A1 ITMI971628A1 (it) | 1999-01-09 |
| IT1293305B1 IT1293305B1 (it) | 1999-02-16 |
Family
ID=11377528
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT97MI001628A IT1293305B1 (it) | 1997-07-09 | 1997-07-09 | Sali di acidi difosfonici e loro impiego farmacologico nel trattamento dell'osteoporosi |
Country Status (17)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100317935B1 (ko) * | 1999-10-20 | 2001-12-22 | 유승필 | 대사성 골질환 치료용 약제조성물 및 이의 제조방법 |
| EA200601630A1 (ru) * | 2004-03-04 | 2007-02-27 | Макото Юаса | Ниосома, имеющая внедрённый в неё маталлопорфириновый комплекс, способ её получения и лекарственное средство с её использованием |
| US7645459B2 (en) | 2004-05-24 | 2010-01-12 | The Procter & Gamble Company | Dosage forms of bisphosphonates |
| US20080286359A1 (en) | 2004-05-24 | 2008-11-20 | Richard John Dansereau | Low Dosage Forms Of Risedronate Or Its Salts |
| US7645460B2 (en) | 2004-05-24 | 2010-01-12 | The Procter & Gamble Company | Dosage forms of risedronate |
| US20080287400A1 (en) | 2004-05-24 | 2008-11-20 | Richard John Dansereau | Low Dosage Forms Of Risedronate Or Its Salts |
| FR2926081B1 (fr) * | 2008-01-03 | 2010-02-19 | Univ Nantes | Derives d'acide hydroxy-bisphosphonique comme vecteur ciblant le tissu osseux |
| EP2266578A4 (de) * | 2008-03-18 | 2011-08-17 | Dikovskiy Aleksander Vladimirovich | Pharmazeutische zusammensetzung zur prävention und behandlung von knochenresorption unterschiedlicher ätiologie |
| KR20110079813A (ko) * | 2008-09-22 | 2011-07-08 | 아이시스 이노베이션 리미티드 | 이미다조〔1,2－α〕피리디닐 비스포스포네이트 |
| US8882740B2 (en) * | 2009-12-23 | 2014-11-11 | Stryker Trauma Gmbh | Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone |
| EP3084483A1 (en) * | 2013-12-19 | 2016-10-26 | 3M Innovative Properties Company | Articles comprising self-assembled layers comprising nanoparticles with a phosphorous surface treatment |
| CN106361701B (zh) * | 2016-08-31 | 2019-08-27 | 上海交通大学 | 一种脂质体药物载体及其制备方法和应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3751372A (en) | 1971-06-18 | 1973-08-07 | Hercules Inc | Scale and corrosion control in circulating water using polyphosphates and organophonic acids |
| GB1508772A (en) | 1975-04-04 | 1978-04-26 | Shell Int Research | Biologically active compositions |
| DD150744A1 (de) | 1980-04-02 | 1981-09-16 | Sigurd Wobst | Verfahren zur kontinuierlichen herstellung von cycloalkylhydroperoxiden |
| IT1201087B (it) | 1982-04-15 | 1989-01-27 | Gentili Ist Spa | Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche |
| DE3434667A1 (de) * | 1984-09-21 | 1986-04-03 | Henkel KGaA, 4000 Düsseldorf | 4-dimethylamino-1-hydroxybutan-1,1-diphosphonsaeure, deren wasserloesliche salze, verfahren zu ihrer herstellung sowie ihre verwendung |
| IT1187828B (it) * | 1985-05-24 | 1987-12-23 | Gentili Ist Spa | Composizione farmaceutica a base di difosfonati per il trattamento dell aretrosi |
| JPS63165457A (ja) | 1986-12-27 | 1988-07-08 | Lion Corp | 導電性樹脂組成物 |
| JPS63286478A (ja) | 1987-05-19 | 1988-11-24 | Lion Corp | 導電性塗料組成物 |
| DD273650A1 (de) | 1988-07-01 | 1989-11-22 | Robotron Elektronik | Verfahren zur chemischen anschlagvernicklung von kupferstrukturen auf dielektrika |
| SK10193A3 (en) | 1990-07-13 | 1993-10-06 | Procter & Gamble | Anticalculus antiplaque compositions using azacycloalkane diphosphonates |
| EP0541037A3 (en) * | 1991-11-06 | 1997-02-26 | Takeda Chemical Industries Ltd | Squalene synthetase inhibitory composition and use thereof |
| CA2077312C (en) * | 1992-09-01 | 2000-02-08 | Ronald L. Oleka | Condensate polisher regenerant system |
| JPH06100576A (ja) * | 1992-09-21 | 1994-04-12 | Kirin Brewery Co Ltd | 骨粗鬆症治療剤または予防剤 |
| JP3238304B2 (ja) * | 1995-08-11 | 2001-12-10 | 三菱重工業株式会社 | スケール溶解液 |
| JP3445426B2 (ja) | 1995-12-26 | 2003-09-08 | 花王株式会社 | 高吸水性樹脂組成物 |
-
1997
- 1997-07-08 US US09/446,617 patent/US6410782B1/en not_active Expired - Fee Related
- 1997-07-09 IT IT97MI001628A patent/IT1293305B1/it active IP Right Grant
-
1998
- 1998-07-08 KR KR10-2000-7000135A patent/KR100396036B1/ko not_active IP Right Cessation
- 1998-07-08 DE DE69818823T patent/DE69818823T2/de not_active Expired - Fee Related
- 1998-07-08 IL IL13317298A patent/IL133172A/xx not_active IP Right Cessation
- 1998-07-08 DK DK98939625T patent/DK0994884T3/da active
- 1998-07-08 CN CNB988069326A patent/CN1161363C/zh not_active Expired - Fee Related
- 1998-07-08 JP JP2000502060A patent/JP3681637B2/ja not_active Expired - Fee Related
- 1998-07-08 PT PT98939625T patent/PT994884E/pt unknown
- 1998-07-08 BR BR9810561-2A patent/BR9810561A/pt not_active Application Discontinuation
- 1998-07-08 EP EP98939625A patent/EP0994884B1/en not_active Expired - Lifetime
- 1998-07-08 ES ES98939625T patent/ES2207853T3/es not_active Expired - Lifetime
- 1998-07-08 AU AU88067/98A patent/AU8806798A/en not_active Abandoned
- 1998-07-08 HU HU0004679A patent/HUP0004679A3/hu unknown
- 1998-07-08 CA CA002303210A patent/CA2303210A1/en not_active Abandoned
- 1998-07-08 AT AT98939625T patent/ATE251631T1/de not_active IP Right Cessation
- 1998-07-08 WO PCT/EP1998/004238 patent/WO1999002539A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001509510A (ja) | 2001-07-24 |
| KR100396036B1 (ko) | 2003-08-27 |
| CN1261892A (zh) | 2000-08-02 |
| EP0994884A1 (en) | 2000-04-26 |
| HUP0004679A2 (hu) | 2001-08-28 |
| BR9810561A (pt) | 2000-08-15 |
| PT994884E (pt) | 2004-02-27 |
| CA2303210A1 (en) | 1999-01-21 |
| WO1999002539A1 (en) | 1999-01-21 |
| AU8806798A (en) | 1999-02-08 |
| EP0994884B1 (en) | 2003-10-08 |
| DK0994884T3 (da) | 2004-02-16 |
| JP3681637B2 (ja) | 2005-08-10 |
| HUP0004679A3 (en) | 2002-04-29 |
| US6410782B1 (en) | 2002-06-25 |
| DE69818823T2 (de) | 2004-05-06 |
| IL133172A (en) | 2005-03-20 |
| IL133172A0 (en) | 2001-03-19 |
| CN1161363C (zh) | 2004-08-11 |
| ES2207853T3 (es) | 2004-06-01 |
| IT1293305B1 (it) | 1999-02-16 |
| KR20010021577A (ko) | 2001-03-15 |
| ATE251631T1 (de) | 2003-10-15 |
| DE69818823D1 (de) | 2003-11-13 |
| ITMI971628A1 (it) | 1999-01-09 |
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| 0001 | Granted |