ITMI952772A0 - - Google Patents
Info
- Publication number
- ITMI952772A0 ITMI952772A0 ITMI952772A ITMI952772A ITMI952772A0 IT MI952772 A0 ITMI952772 A0 IT MI952772A0 IT MI952772 A ITMI952772 A IT MI952772A IT MI952772 A ITMI952772 A IT MI952772A IT MI952772 A0 ITMI952772 A0 IT MI952772A0
- Authority
- IT
- Italy
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Seasonings (AREA)
- Detergent Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT95MI002772A IT1277736B1 (it) | 1995-12-28 | 1995-12-28 | Derivati tiolici ad attivita' inibitrice delle metallopeptidasi |
DE69634387T DE69634387D1 (de) | 1995-12-28 | 1996-12-09 | Mercapto derivate mit metallopeptidase(ace/nep) inhibiernder wirkung |
AT96943903T ATE289597T1 (de) | 1995-12-28 | 1996-12-09 | Mercapto derivate mit metallopeptidase(ace/nep) inhibiernder wirkung |
PCT/EP1996/005496 WO1997024341A1 (en) | 1995-12-28 | 1996-12-09 | Thiol derivatives with metallopeptidase (ace/nep) inhibitory activity |
EP96943903A EP0883612B1 (en) | 1995-12-28 | 1996-12-09 | Thiol derivatives with metallopeptidase (ace/nep) inhibitory activity |
US09/091,415 US6166051A (en) | 1995-12-28 | 1996-12-09 | Thiol derivatives with metallopeptidase (ACE/NEP) inhibitory activity |
CA002241452A CA2241452A1 (en) | 1995-12-28 | 1996-12-09 | Thiol derivatives with metallopeptidase (ace/nep) inhibitory activity |
KR1019980704933A KR19990076808A (ko) | 1995-12-28 | 1996-12-09 | 메탈로펩티다아제(ace/nep) 억제 활성을 갖는티올 유도체 |
AU13691/97A AU706978B2 (en) | 1995-12-28 | 1996-12-09 | Thiol derivatives with metallopeptidase (ACE/NEP) inhibitory activity |
HU9903840A HUP9903840A3 (en) | 1995-12-28 | 1996-12-09 | N-mercaptoacyl alanine derivatives with metallopeptidase (ace/nep) inhibitory activity, process for their preparation and pharmaceutical compositions containing them |
CN96199355A CN1108295C (zh) | 1995-12-28 | 1996-12-09 | 具有金属肽酶(ace/nep)抑制活性的巯基衍生物 |
CZ19982047A CZ295804B6 (cs) | 1995-12-28 | 1996-12-09 | Thiolová sloučenina, způsob její přípravy a prostředek, který ji obsahuje |
EA199800546A EA002339B1 (ru) | 1995-12-28 | 1996-12-09 | Тиольные производные, обладающие ингибирующей активностью в отношении металлопептидаз (ace/nep) |
ZA9610819A ZA9610819B (en) | 1995-12-28 | 1996-12-20 | Thiol derivatives with metallopeptidase inhibitory activity |
MX9805168A MX9805168A (es) | 1995-12-28 | 1998-06-25 | Derivados de tiol con actividad inhibitoria de la metalopeptidasa (ace-nep). |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT95MI002772A IT1277736B1 (it) | 1995-12-28 | 1995-12-28 | Derivati tiolici ad attivita' inibitrice delle metallopeptidasi |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI952772A0 true ITMI952772A0 (it) | 1995-12-28 |
ITMI952772A1 ITMI952772A1 (it) | 1997-06-28 |
IT1277736B1 IT1277736B1 (it) | 1997-11-12 |
Family
ID=11372826
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT95MI002772A IT1277736B1 (it) | 1995-12-28 | 1995-12-28 | Derivati tiolici ad attivita' inibitrice delle metallopeptidasi |
Country Status (15)
Country | Link |
---|---|
US (1) | US6166051A (it) |
EP (1) | EP0883612B1 (it) |
KR (1) | KR19990076808A (it) |
CN (1) | CN1108295C (it) |
AT (1) | ATE289597T1 (it) |
AU (1) | AU706978B2 (it) |
CA (1) | CA2241452A1 (it) |
CZ (1) | CZ295804B6 (it) |
DE (1) | DE69634387D1 (it) |
EA (1) | EA002339B1 (it) |
HU (1) | HUP9903840A3 (it) |
IT (1) | IT1277736B1 (it) |
MX (1) | MX9805168A (it) |
WO (1) | WO1997024341A1 (it) |
ZA (1) | ZA9610819B (it) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2805259B1 (fr) * | 2000-02-17 | 2002-03-29 | Inst Nat Sante Rech Med | Nouveaux derives d'aminoacides n-mercaptoacyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US8307671B2 (en) * | 2008-09-22 | 2012-11-13 | Jungerhans Robert R J | Purification of gases in synthesis gas production process |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4199512A (en) * | 1976-05-10 | 1980-04-22 | E. R. Squibb & Sons, Inc. | Compounds for alleviating hypertension |
EP0566157A1 (en) * | 1986-06-20 | 1993-10-20 | Schering Corporation | Neutral metalloendopeptidase inhibitors in the treatment of hypertension |
FR2652087B1 (fr) * | 1989-09-15 | 1993-10-15 | Bioprojet Ste Civile | Derives d'amino-acides, leur procede de preparation et leurs applications therapeutiques. |
US5599951A (en) * | 1989-09-15 | 1997-02-04 | Societe Civile Bioprojet | Amino acid derivatives, the process for their preparation and their applications to therapy |
CA2038379C (en) * | 1990-03-22 | 2002-11-05 | Norma G. Delaney | Trifluoromethyl mercaptan and mercaptoacyl derivatives and method of using same |
US5223516A (en) * | 1990-03-22 | 1993-06-29 | E. R. Squibb & Sons, Inc. | 3,3,3-trifluoro-2-mercaptomethyl-N-tetrazolyl substituted propanamides and method of using same |
FR2679564A1 (fr) * | 1991-07-23 | 1993-01-29 | Inst Nat Sante Rech Med | Nouveaux acylmercaptoalcanoldipeptides, leur preparation et les compositions qui les contiennent. |
US5225401A (en) * | 1991-08-12 | 1993-07-06 | E. R. Squibb & Sons, Inc. | Treatment of congestive heart failure |
FR2682952B1 (fr) * | 1991-10-25 | 1993-12-03 | Institut Nal Sante Recherc Medic | Nouveaux n-(mercaptoacyl) amino-acides, leur preparation et les compositions pharmaceutiques qui les contiennent. |
WO1994017036A1 (en) * | 1993-01-22 | 1994-08-04 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | S-lipophilic aliphatic carbonyl [n-mercaptoacyl-(amino acid or peptide)] compounds as antihypertensive agents |
JPH0841015A (ja) * | 1994-07-27 | 1996-02-13 | Fujisawa Pharmaceut Co Ltd | 新規メルカプト−アミド誘導体 |
IT1273455B (it) * | 1995-01-27 | 1997-07-08 | Zambon Spa | Derivati tiolici ad attivita' inibitrice delle metallopeptidasi |
-
1995
- 1995-12-28 IT IT95MI002772A patent/IT1277736B1/it active IP Right Grant
-
1996
- 1996-12-09 EA EA199800546A patent/EA002339B1/ru not_active IP Right Cessation
- 1996-12-09 DE DE69634387T patent/DE69634387D1/de not_active Expired - Lifetime
- 1996-12-09 CN CN96199355A patent/CN1108295C/zh not_active Expired - Fee Related
- 1996-12-09 CA CA002241452A patent/CA2241452A1/en not_active Abandoned
- 1996-12-09 KR KR1019980704933A patent/KR19990076808A/ko active IP Right Grant
- 1996-12-09 AT AT96943903T patent/ATE289597T1/de not_active IP Right Cessation
- 1996-12-09 EP EP96943903A patent/EP0883612B1/en not_active Expired - Lifetime
- 1996-12-09 WO PCT/EP1996/005496 patent/WO1997024341A1/en active IP Right Grant
- 1996-12-09 CZ CZ19982047A patent/CZ295804B6/cs not_active IP Right Cessation
- 1996-12-09 AU AU13691/97A patent/AU706978B2/en not_active Ceased
- 1996-12-09 HU HU9903840A patent/HUP9903840A3/hu unknown
- 1996-12-09 US US09/091,415 patent/US6166051A/en not_active Expired - Fee Related
- 1996-12-20 ZA ZA9610819A patent/ZA9610819B/xx unknown
-
1998
- 1998-06-25 MX MX9805168A patent/MX9805168A/es not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HUP9903840A3 (en) | 2001-12-28 |
CZ295804B6 (cs) | 2005-11-16 |
EP0883612A1 (en) | 1998-12-16 |
EA002339B1 (ru) | 2002-04-25 |
CN1108295C (zh) | 2003-05-14 |
US6166051A (en) | 2000-12-26 |
CZ204798A3 (cs) | 1998-11-11 |
CA2241452A1 (en) | 1997-07-10 |
EA199800546A1 (ru) | 1999-02-25 |
HUP9903840A2 (hu) | 2000-03-28 |
ZA9610819B (en) | 1997-06-24 |
IT1277736B1 (it) | 1997-11-12 |
ATE289597T1 (de) | 2005-03-15 |
WO1997024341A1 (en) | 1997-07-10 |
AU706978B2 (en) | 1999-07-01 |
ITMI952772A1 (it) | 1997-06-28 |
KR19990076808A (ko) | 1999-10-15 |
MX9805168A (es) | 1998-10-31 |
AU1369197A (en) | 1997-07-28 |
DE69634387D1 (de) | 2005-03-31 |
CN1268945A (zh) | 2000-10-04 |
EP0883612B1 (en) | 2005-02-23 |
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Legal Events
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---|---|---|---|
0001 | Granted |