ITMI20062102A1 - Nuovui sali di 3-benzil-2-metil-2,3,3a,4,5,6,7,7a-ottaidrobenzo-d-isossazol-4-one - Google Patents

Nuovui sali di 3-benzil-2-metil-2,3,3a,4,5,6,7,7a-ottaidrobenzo-d-isossazol-4-one

Info

Publication number
ITMI20062102A1
ITMI20062102A1 IT002102A ITMI20062102A ITMI20062102A1 IT MI20062102 A1 ITMI20062102 A1 IT MI20062102A1 IT 002102 A IT002102 A IT 002102A IT MI20062102 A ITMI20062102 A IT MI20062102A IT MI20062102 A1 ITMI20062102 A1 IT MI20062102A1
Authority
IT
Italy
Prior art keywords
benzyl
methyl
octoidrobenzo
isossazol
new salts
Prior art date
Application number
IT002102A
Other languages
English (en)
Italian (it)
Inventor
Laura Dini
Fabio Neggiani
Original Assignee
Abiogen Pharma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abiogen Pharma Spa filed Critical Abiogen Pharma Spa
Priority to IT002102A priority Critical patent/ITMI20062102A1/it
Priority to CA002667515A priority patent/CA2667515A1/en
Priority to MX2009004294A priority patent/MX2009004294A/es
Priority to AU2007315833A priority patent/AU2007315833A1/en
Priority to MX2009004293A priority patent/MX2009004293A/es
Priority to BRPI0718391-7A priority patent/BRPI0718391A2/pt
Priority to EP07825550A priority patent/EP2094675B1/en
Priority to RSP-2009/0389A priority patent/RS20090389A/sr
Priority to NZ577978A priority patent/NZ577978A/en
Priority to JP2009535824A priority patent/JP2010509309A/ja
Priority to PCT/IB2007/003292 priority patent/WO2008053326A1/en
Priority to CA002667513A priority patent/CA2667513A1/en
Priority to PCT/IB2007/003291 priority patent/WO2008053325A1/en
Priority to KR1020097011322A priority patent/KR20090082452A/ko
Priority to AT07825549T priority patent/ATE502021T1/de
Priority to EP07825549A priority patent/EP2094674B1/en
Priority to CNA2007800406598A priority patent/CN101535281A/zh
Priority to BRPI0718392-5A priority patent/BRPI0718392A2/pt
Priority to KR1020097011287A priority patent/KR20090077014A/ko
Priority to HR20090477A priority patent/HRP20090477A2/hr
Priority to AU2007315832A priority patent/AU2007315832A1/en
Priority to US12/513,352 priority patent/US20100069451A1/en
Priority to RSP-2009/0388A priority patent/RS20090388A/sr
Priority to US12/513,351 priority patent/US20100069450A1/en
Priority to RU2009120667/04A priority patent/RU2009120667A/ru
Priority to AT07825550T priority patent/ATE504578T1/de
Priority to RU2009120724/04A priority patent/RU2009120724A/ru
Priority to HR20090470A priority patent/HRP20090470A2/hr
Priority to JP2009535825A priority patent/JP2010509310A/ja
Priority to DE602007013278T priority patent/DE602007013278D1/de
Priority to DE602007013801T priority patent/DE602007013801D1/de
Priority to CNA2007800406691A priority patent/CN101535282A/zh
Priority to NZ577311A priority patent/NZ577311A/en
Publication of ITMI20062102A1 publication Critical patent/ITMI20062102A1/it
Priority to IL198444A priority patent/IL198444A0/en
Priority to IL198443A priority patent/IL198443A0/en
Priority to ZA200903618A priority patent/ZA200903618B/xx
Priority to NO20092114A priority patent/NO20092114L/no
Priority to NO20092115A priority patent/NO20092115L/no
Priority to ZA200903810A priority patent/ZA200903810B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT002102A 2006-11-02 2006-11-02 Nuovui sali di 3-benzil-2-metil-2,3,3a,4,5,6,7,7a-ottaidrobenzo-d-isossazol-4-one ITMI20062102A1 (it)

Priority Applications (39)

Application Number Priority Date Filing Date Title
IT002102A ITMI20062102A1 (it) 2006-11-02 2006-11-02 Nuovui sali di 3-benzil-2-metil-2,3,3a,4,5,6,7,7a-ottaidrobenzo-d-isossazol-4-one
AU2007315832A AU2007315832A1 (en) 2006-11-02 2007-10-31 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
HR20090477A HRP20090477A2 (hr) 2006-11-02 2007-10-31 SOL 3-BENZIL-2-METIL-2,3,3A,4,5,6,7,7A-OKTAHIDROBENZO[d]IZOKSAZOL-4-ONA
AU2007315833A AU2007315833A1 (en) 2006-11-02 2007-10-31 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
MX2009004293A MX2009004293A (es) 2006-11-02 2007-10-31 Una sal de 3-bencil-2-metil-2,3,3a,4,5,6,7,7a-octahidrobenzo[d]iso xasol-4-ona.
BRPI0718391-7A BRPI0718391A2 (pt) 2006-11-02 2007-10-31 SAL DO COMPOSTO DE 3-BENZIL-2-METIL-2,3,3a,4,5,6,7,7a-OCTAIDROBENZO [D] ISOXAZOL-4-ONA
EP07825550A EP2094675B1 (en) 2006-11-02 2007-10-31 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
RSP-2009/0389A RS20090389A (sr) 2006-11-02 2007-10-31 So 3-benzil-2-metil-2,3,3a,4,5,6,7,7a-oktahidrobenzo (d)izoksazol-4-ona
NZ577978A NZ577978A (en) 2006-11-02 2007-10-31 The fumarate salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
JP2009535824A JP2010509309A (ja) 2006-11-02 2007-10-31 ３−ベンジル−２−メチル−２，３，３ａ，４，５，６，７，７ａ−オクタヒドロベンゾ［ｄ］イソオキサゾール−４−オンの塩
PCT/IB2007/003292 WO2008053326A1 (en) 2006-11-02 2007-10-31 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
CA002667513A CA2667513A1 (en) 2006-11-02 2007-10-31 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
PCT/IB2007/003291 WO2008053325A1 (en) 2006-11-02 2007-10-31 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
KR1020097011322A KR20090082452A (ko) 2006-11-02 2007-10-31 3-벤질-2-메틸-2,3,3ａ,4,5,6,7,7ａ-옥타히드로벤조[ｄ]이속사졸-4-온의 염
AT07825549T ATE502021T1 (de) 2006-11-02 2007-10-31 Salz von 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a- octahydrobenzoädüisoxazol-4-on
EP07825549A EP2094674B1 (en) 2006-11-02 2007-10-31 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
CNA2007800406598A CN101535281A (zh) 2006-11-02 2007-10-31 3-苄基-2-甲基-2，3，3a，4，5，6，7，7a-八氢苯并[d]异噁唑-4-酮的盐
MX2009004294A MX2009004294A (es) 2006-11-02 2007-10-31 Una sal de 3-bencil-2-metil-2,3,3a,4,5,6,7,7a-octahidrobenzo[d]iso xasol-4-ona.
KR1020097011287A KR20090077014A (ko) 2006-11-02 2007-10-31 3-벤질-2-메틸-2,3,3ａ,4,5,6,7,7ａ-옥타히드로벤조[ｄ]이속사졸-4-온의 염
CA002667515A CA2667515A1 (en) 2006-11-02 2007-10-31 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
BRPI0718392-5A BRPI0718392A2 (pt) 2006-11-02 2007-10-31 SAL COMPOSTO DE 3-BENZIL-2-METIL-2,3,3a,4,5,6,7,7a-OCTAIDROBENZO [d] ISOXAZOL-4-ONA
RU2009120667/04A RU2009120667A (ru) 2006-11-02 2007-10-31 Соль 3-бензил-2-метил-2,3,3а,4,5,6,7,7а-октагидробензо[d]изоксазол-4-она
RSP-2009/0388A RS20090388A (sr) 2006-11-02 2007-10-31 So 3 - benzil - 2 - metil - 2,3,3a,4,5,6,7,7a - oktahidrobenzo(d)izoksazol-4-ona
US12/513,351 US20100069450A1 (en) 2006-11-02 2007-10-31 Salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7, 7a- octahydrobenzo[d]isoxazol-4-one
US12/513,352 US20100069451A1 (en) 2006-11-02 2007-10-31 Salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7, 7a- octahydrobenzo[d]isoxazol-4-one
AT07825550T ATE504578T1 (de) 2006-11-02 2007-10-31 Salz von 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a- octahydrobenzoädüisoxazol-4-on
RU2009120724/04A RU2009120724A (ru) 2006-11-02 2007-10-31 Соль 3-бензил-2-метил-2,3,3а,4,5,6,7,7а-октагидробензо[d]изоксазол-4-она
HR20090470A HRP20090470A2 (hr) 2006-11-02 2007-10-31 Sol 3-benzil-2-methil-2.3.3.a.4.5.6.7,7a-octahidrobenzo[d]isoksazol-4-ona
JP2009535825A JP2010509310A (ja) 2006-11-02 2007-10-31 ３−ベンジル−２−メチル−２，３，３ａ，４，５，６，７，７ａ−オクタヒドロベンゾ［ｄ］イソオキサゾール−４−オンの塩
DE602007013278T DE602007013278D1 (de) 2006-11-02 2007-10-31 Salz von 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzoädüisoxazol-4-on
DE602007013801T DE602007013801D1 (de) 2006-11-02 2007-10-31 Salz von 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzoädüisoxazol-4-on
CNA2007800406691A CN101535282A (zh) 2006-11-02 2007-10-31 3-苄基-2-甲基-2，3，3a，4，5，6，7，7a-八氢苯并[d]异噁唑-4-酮的盐
NZ577311A NZ577311A (en) 2006-11-02 2007-10-31 The oxalate salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
IL198444A IL198444A0 (en) 2006-11-02 2009-04-28 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-
IL198443A IL198443A0 (en) 2006-11-02 2009-04-28 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-
ZA200903618A ZA200903618B (en) 2006-11-02 2009-05-25 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
NO20092114A NO20092114L (no) 2006-11-02 2009-05-29 Salt av 3-benzyl-2-metyl-2,3,3a,4,5,6,7,7a-oktahydrobenzo[d]isoksazol-4-on
NO20092115A NO20092115L (no) 2006-11-02 2009-05-29 Salt av 3-benzyl-2-metyl-2,3,3a,4,5,6,7,7a-oktahydrobenzo[d]isoksazol-4-on
ZA200903810A ZA200903810B (en) 2006-11-02 2009-06-01 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002102A ITMI20062102A1 (it) 2006-11-02 2006-11-02 Nuovui sali di 3-benzil-2-metil-2,3,3a,4,5,6,7,7a-ottaidrobenzo-d-isossazol-4-one

Publications (1)

Publication Number Publication Date
ITMI20062102A1 true ITMI20062102A1 (it) 2008-05-03

Family

ID=39145485

Family Applications (1)

Application Number Title Priority Date Filing Date
IT002102A ITMI20062102A1 (it) 2006-11-02 2006-11-02 Nuovui sali di 3-benzil-2-metil-2,3,3a,4,5,6,7,7a-ottaidrobenzo-d-isossazol-4-one

Country Status (20)

Country Link
US (2) US20100069450A1 (enExample)
EP (2) EP2094674B1 (enExample)
JP (2) JP2010509309A (enExample)
KR (2) KR20090082452A (enExample)
CN (2) CN101535281A (enExample)
AT (2) ATE502021T1 (enExample)
AU (2) AU2007315832A1 (enExample)
BR (2) BRPI0718392A2 (enExample)
CA (2) CA2667515A1 (enExample)
DE (2) DE602007013278D1 (enExample)
HR (2) HRP20090477A2 (enExample)
IL (2) IL198443A0 (enExample)
IT (1) ITMI20062102A1 (enExample)
MX (2) MX2009004294A (enExample)
NO (2) NO20092115L (enExample)
NZ (2) NZ577978A (enExample)
RS (2) RS20090389A (enExample)
RU (2) RU2009120724A (enExample)
WO (2) WO2008053326A1 (enExample)
ZA (2) ZA200903618B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2112142A1 (en) * 2008-04-24 2009-10-28 Abiogen Pharma S.p.A. Process for preparing a crystalline form compound of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
ITMI20080768A1 (it) * 2008-04-24 2009-10-25 Abiogen Pharma Spa Procedimento per la preparazione di un composto in forma cristallina di 3-benzil-2-metil-2,3,3a,4,5,6,7,7a-ottaidro-benzo[d]isossazol-4-one
EP2218721A1 (en) * 2009-02-11 2010-08-18 LEK Pharmaceuticals d.d. Novel salts of sitagliptin
WO2011010332A1 (en) * 2009-07-23 2011-01-27 Abiogen Pharma S.P.A. Process for preparing rel-(3r*,3as*,7as*)-3-benzyl-2-methyl-2,3, 3a,4,5,6,7,7a- octahydrobenzo[d]isoxazoi-4-one or a salt thereof
US10131642B1 (en) * 2015-01-30 2018-11-20 Boehringer Ingelheim International Gmbh Aldosterone synthase inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4161595A (en) * 1978-10-02 1979-07-17 Bristol-Myers Company Levulinic acid salt
US4419358A (en) * 1981-11-12 1983-12-06 Mead Johnson & Company Isethionic acid salt of 9-cyclohexyl-2-propoxy-9H-purine-6-amine and compositions containing an effective bronchodilating concentration of it
GB2264299B (en) * 1992-02-19 1995-07-26 British Tech Group Iso-oxazolidine derivatives

Also Published As

Publication number Publication date
CN101535281A (zh) 2009-09-16
EP2094675A1 (en) 2009-09-02
RU2009120724A (ru) 2010-12-10
WO2008053325A1 (en) 2008-05-08
DE602007013801D1 (de) 2011-05-19
HRP20090477A2 (hr) 2009-11-30
CA2667513A1 (en) 2008-05-08
JP2010509309A (ja) 2010-03-25
ZA200903618B (en) 2010-07-28
DE602007013278D1 (de) 2011-04-28
EP2094675B1 (en) 2011-04-06
NZ577978A (en) 2010-10-29
CA2667515A1 (en) 2008-05-08
ATE504578T1 (de) 2011-04-15
AU2007315832A1 (en) 2008-05-08
BRPI0718391A2 (pt) 2013-11-26
AU2007315833A1 (en) 2008-05-08
US20100069450A1 (en) 2010-03-18
US20100069451A1 (en) 2010-03-18
MX2009004294A (es) 2009-05-08
RS20090388A (sr) 2010-12-31
KR20090077014A (ko) 2009-07-13
HRP20090470A2 (hr) 2009-11-30
JP2010509310A (ja) 2010-03-25
RS20090389A (sr) 2010-12-31
IL198444A0 (en) 2010-02-17
WO2008053326A1 (en) 2008-05-08
EP2094674B1 (en) 2011-03-16
NO20092114L (no) 2009-05-29
NO20092115L (no) 2009-05-29
IL198443A0 (en) 2010-02-17
RU2009120667A (ru) 2010-12-10
EP2094674A1 (en) 2009-09-02
CN101535282A (zh) 2009-09-16
ATE502021T1 (de) 2011-04-15
BRPI0718392A2 (pt) 2013-11-26
ZA200903810B (en) 2010-07-28
NZ577311A (en) 2010-10-29
MX2009004293A (es) 2009-05-08
KR20090082452A (ko) 2009-07-30

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